Carol A. Lange - Publications, H-index & Citations

In memoriam: Brian J. Harvey 纪念：Brian J. Harvey

IF3.3

2025-12-01

PREAI

Gillis, Noelle E.; Schmidt, Susan, I; Lange, Carol A.

JOURNAL OF PHYSIOLOGY-LONDON

IF4.4

2025-11-01

PREAI

Barton, Matthias; Lange, Carol A.; Levin, Ellis R.; Prossnitz, Eric R.; Rossi, Gian Paolo; Rapetti-mauss, Raphael

Regulation of Super Enhancers by Phosphorylated Progesterone Receptors Drives Breast Cancer Stem Cell Expansion 磷酸化孕酮受体对超增强子的调控驱动乳腺癌干细胞扩增

Stemness-targeted therapies to inhibit cancer cell plasticity in triple negative breast cancer 靶向干细胞特性的疗法以抑制三阴性乳腺癌的癌细胞可塑性

IF3.3

2025-04-21

PREAI

Gillis, Noelle E.; Lange, Carol A.

ANNALS OF ONCOLOGY

IF65.4

2024-09-01

PREAI

Takchi, A.; Haddad, T.; Zhang, M.; Jalalirad, M.; Suman, V.; Wang, L.; Lange, C.; Ingle, J.; Goetz, M. P.; DAssoro, A. B.

Progesterone Receptor Signaling Promotes Cancer Associated Fibroblast Mediated Tumorigenicity in ER plus Breast Cancer

Blockade of tumor cell-intrinsic PD-L1 signaling enhances AURKA-targeted therapy in triple negative breast cancer 阻断肿瘤细胞内在PD-L1信号增强三阴性乳腺癌的AURKA靶向治疗

IF3.3

2024-07-23

PREAI

Diep, Caroline H.; Spartz, Angela; Truong, Thu H.; Dwyer, Amy R.; El-Ashry, Dorraya; Lange, Carol A.

FRONTIERS IN ONCOLOGY

IF3.3

2024-05-30

OAAI

Takchi, Andrew; Zhang, Minzhi; Jalalirad, Mohammad; Ferre, Roberto Leon; Shrestha, Royal; Haddad, Tufia; Sarkaria, Jann; Tuma, Ann; Carter, Jodi; David, Hillman; Giridhar, Karthik; Wang, Liewei; Lange, Carol; Lendahl, Urban; Ingle, James; Goetz, Matthew; D'Assoro, Antonino Bonaventura

Mechanisms of endocrine resistance to letrozole, fulvestrant, and palbociclib are associated with increased sensitivity to hexyl-cuban-1-yl biguanide inhibitors of CYP3A4 mediated epoxyeicosatrienoic acid biosynthesis

Context matters: Genomic profiling of PR isoform-specific actions in breast cancer stem cells reveals novel therapeutic insights for ER plus breast cancer

IF16.6

2024-04-05

PREAI

Guo, Zhijun; Lei, Jianxun; Makovec, Allison; Jayaraman, Swaathi; Hawse, John R.; Lange, Carol; Ambrose, Elizabeth; Georg, Gunda I.; D'Assoro, Tony; Matthew, Goetz P.; Potter, David A.

Glucocorticoid Receptors Drive Breast Cancer Cell Migration and Metabolic Reprogramming via PDK4

IF16.6

2024-03-22

PREAI

Gillis, Noelle E.; Truong, Thu H.; Finlay-Schultz, Jessica; Sartorius, Carol A.; Lange, Carol A.

Receptor for hyaluronan-mediated motility (RHAMM) defines an invasive niche associated with tumor progression and predicts poor outcomes in breast cancer patients 透明质酸介导的运动受体 (RHAMM) 定义了与肿瘤进展相关的侵袭性生态位，并预测乳腺癌患者的不良预后

IF3.3

2023-05-24

PREAI

Dwyer, Amy R.; Kerkvliet, Carlos Perez; Truong, Thu H.; Hagen, Kyla M.; Krutilina, Raisa, I; Parke, Deanna N.; Oakley, Robert H.; Liddle, Christopher; Cidlowski, John A.; Seagroves, Tiffany N.; Lange, Carol A.

JOURNAL OF PATHOLOGY

IF5.2

2023-04-26

OAAI

Tarullo, Sarah E.; He, Yuyu; Daughters, Claire; Knutson, Todd P.; Henzler, Christine M.; Price, Matthew A.; Shanley, Ryan; Witschen, Patrice; Tolg, Cornelia; Kaspar, Rachael E.; Hallstrom, Caroline; Gittsovich, Lyubov; Sulciner, Megan L.; Zhang, Xihong; Forster, Colleen L.; Lange, Carol A.; Shats, Oleg; Desler, Michelle; Cowan, Kenneth H.; Yee, Douglas; Schwertfeger, Kathryn L.; Turley, Eva A.; McCarthy, James B.; Nelson, Andrew C.

Progesterone receptor mediated crosstalk between cancer associated fibroblasts (CAFs) and ER plus /PR plus breast cancer cells through CAF-secreted FGF2

Transcriptional hyperactivity of human progesterone receptors is coupled to their ligand-dependent down-regulation by mitogen-activated protein kinase-dependent phosphorylation of serine 294

IF16.6

2023-04-04

PREAI

Spartz, Angela K.; Diep, Caroline H.; Lange, Carol A.; El-Ashry, Dorraya

Progesterone receptors upregulate Wnt-1 to induce epidermal growth factor receptor transactivation and c-Src-dependent sustained activation of Erk1/2 mitogen-activated protein kinase in breast cancer cells

IF2.7

2023-03-28

204

OAAI

Shen, TJ; Horwitz, KB; Lange, CA

Phosphorylation of progesterone receptor serine 400 mediates ligand-independent transcriptional activity in response to activation of cyclin-dependent protein kinase 2

IF2.7

2023-03-27

208

OAAI

Faivre, Emily J.; Lange, Carol A.

ck2-Dependent Phosphorylation of Progesterone Receptors (PR) on Ser81 Regulates PR-B Isoform-Specific Target Gene Expression in Breast Cancer Cells

IF2.7

2023-03-27

131

OAAI

Pierson-Mullany, LK; Lange, CA

The SMILE Study: A phase II trial of onapristone in combination with fulvestrant for patients with ER-positive and HER2-negative metastatic breast cancer after progression on endocrine therapy and CDK 4/6 inhibitors

IF2.7

2023-03-20

OAAI

Hagan, Christy R.; Regan, Tarah M.; Dressing, Gwen E.; Lange, Carol A.

Primary results of ONAWA (SOLTI-1802) trial: A window of opportunity trial of onapristone in postmenopausal women with progesterone receptor-positive/HER2-negative early breast cancer (EBC)

IF16.6

2023-03-01

PREAI

Kamaraju, Sailaja; Fowler, Amy; Chaudhary, Lubna N.; Burkard, Mark; Giever, Thomas; Hegeman, Robert N.; Pipp-Dahm, Michele; Cheng, Yee Chung; Lange, Carol; Jorns, Julie M.; Stella, Amy; Siddiqui, Nauman; Zurbriggen, Luke; Rajguru, Saurabh; Tarima, Sergey; Sriram, Deepika; Retseck, Janet; Rui, Hallgeir; Sahmoud, Tarek; Wisinski, Kari B.

The SMILE study: A phase 2 trial of onapristone in combination with fulvestrant for patients with ER+ and HER2-metastatic breast cancer after progression on endocrine therapy and CDK4/6 inhibitors

IF16.6

2022-02-15

PREAI

Bellet, Meritxell; Morales, Serafin; Gasol, Ariadna; Amillano, Kepa; Chic, Nuria; Gonzalez-Farre, Xavier; Villagrasa, Patricia; Pare, Laia; Falato, Claudette; Nuciforo, Paolo; Martinez, Debora; Ferrero-Cafiero, Juan M.; Pascual, Tomas; Prat, Aleix; Lange, Carol; Saura, Cristina