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Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants 通过多祖先全基因组发现187种新的风险变异来表征前列腺癌风险 Wang, Anqi; Shen, Jiayi; Rodriguez, Alex A.; Saunders, Edward J.; Chen, Fei; Janivara, Rohini; Darst, Burcu F.; Sheng, Xin; Xu, Yili; Chou, Alisha J.; Benlloch, Sara; Dadaev, Tokhir; Brook, Mark N.; Plym, Anna; Sahimi, Ali; Hoffman, Thomas J.; Takahashi, Atushi; Matsuda, Koichi; Momozawa, Yukihide; Fujita, Masashi; Laisk, Triin; Figueredo, Jessica; Muir, Kenneth; Ito, Shuji; Liu, Xiaoxi; Uchio, Yuji; Kubo, Michiaki; Kamatani, Yoichiro; Lophatananon, Artitaya; Wan, Peggy; Andrews, Caroline; Lori, Adriana; Choudhury, Parichoy P.; Schleutker, Johanna; Tammela, Teuvo L. J.; Sipeky, Csilla; Auvinen, Anssi; Giles, Graham G.; Southey, Melissa C.; MacInnis, Robert J.; Cybulski, Cezary; Wokolorczyk, Dominika; Lubinski, Jan; Rentsch, Christopher T.; Cho, Kelly; Mcmahon, Benjamin H.; Neal, David E.; Donovan, Jenny L.; Hamdy, Freddie C.; Martin, Richard M.; Nordestgaard, Borge G.; Nielsen, Sune F.; Weischer, Maren; Bojesen, Stig E.; Roder, Andreas; Stroomberg, Hein V.; Batra, Jyotsna; Chambers, Suzanne; Horvath, Lisa; Clements, Judith A.; Tilly, Wayne; Risbridger, Gail P.; Gronberg, Henrik; Aly, Markus; Szulkin, Robert; Eklund, Martin; Nordstrom, Tobias; Pashayan, Nora; Dunning, Alison M.; Ghoussaini, Maya; Travis, Ruth C.; Key, Tim J.; Riboli, Elio; Park, Jong Y.; Sellers, Thomas A.; Lin, Hui-Yi; Albanes, Demetrius; Weinstein, Stephanie; Cook, Michael B.; Mucci, Lorelei A.; Giovannucci, Edward; Lindstrom, Sara; Kraft, Peter; Hunter, David J.; Penney, Kathryn L.; Turman, Constance; Tangen, Catherine M.; Goodman, Phyllis J.; Thompson, Ian M., Jr.; Hamilton, Robert J.; Fleshner, Neil E.; Finelli, Antonio; Parent, Marie-Elise; Stanford, Janet L.; Ostrander, Elaine A.; Koutros, Stella; Freeman, Laura E. Beane; Stampfer, Meir; Wolk, Alicja; Hakansson, Niclas; Andriole, Gerald L.; Hoover, Robert N.; Machiela, Mitchell J.; Sorensen, Karina Dalsgaard; Borre, Michael; Blot, William J.; Zheng, Wei; Yeboah, Edward D.; Mensah, James E.; Lu, Yong-Jie; Zhang, Hong-Wei; Feng, Ninghan; Mao, Xueying; Wu, Yudong; Zhao, Shan-Chao; Sun, Zan; Thibodeau, Stephen N.; McDonnell, Shannon K.; Schaid, Daniel J.; West, Catharine M. L.; Barnett, Gill; Maier, Christiane; Schnoeller, Thomas; Luedeke, Manuel; Kibel, Adam S.; Drake, Bettina F.; Cussenot, Olivier; Cancel-Tassin, Geraldine; Menegaux, Florence; Truong, Therese; Koudou, Yves Akoli; John, Esther M.; Grindedal, Eli Marie; Maehle, Lovise; Khaw, Kay-Tee; Ingles, Sue A.; Stern, Mariana C.; Vega, Ana; Gomez-Caamano, Antonio; Fachal, Laura; Rosenstein, Barry S.; Kerns, Sarah L.; Ostrer, Harry; Teixeira, Manuel R.; Paulo, Paula; Brandao, Andreia; Watya, Stephen; Lubwama, Alexander; Bensen, Jeannette T.; Butler, Ebonee N.; Mohler, James L.; Taylor, Jack A.; Kogevinas, Manolis; Dierssen-Sotos, Trinidad; Castano-Vinyals, Gemma; Cannon-Albright, Lisa; Teerlink, Craig C.; Huff, Chad D.; Pilie, Patrick; Yu, Yao; Bohlender, Ryan J.; Gu, Jian; Strom, Sara S.; Multigner, Luc; Blanchet, Pascal; Brureau, Laurent; Kaneva, Radka; Slavov, Chavdar; Mitev, Vanio; Leach, Robin J.; Brenner, Hermann; Chen, Xuechen; Holleczek, Bernd; Schoettker, Ben; Klein, Eric A.; Hsing, Ann W.; Kittles, Rick A.; Murphy, Adam B.; Logothetis, Christopher J.; Kim, Jeri; Neuhausen, Susan L.; Steele, Linda; Ding, Yuan Chun; Isaacs, William B.; Nemesure, Barbara; Hennis, Anselm J. M.; Carpten, John; Pandha, Hardev; Michael, Agnieszka; De Ruyck, Kim; De Meerleer, Gert; Ost, Piet; Xu, Jianfeng; Razack, Azad; Lim, Jasmine; Teo, Soo-Hwang; Newcomb, Lisa F.; Lin, Daniel W.; Fowke, Jay H.; Neslund-Dudas, Christine M.; Rybicki, Benjamin A.; Gamulin, Marija; Lessel, Davor; Kulis, Tomislav; Usmani, Nawaid; Abraham, Aswin; Singhal, Sandeep; Parliament, Matthew; Claessens, Frank; Joniau, Steven; Van den Broeck, Thomas; Gago-Dominguez, Manuela; Castelao, Jose Esteban; Martinez, Maria Elena; Larkin, Samantha; Townsend, Paul A.; Aukim-Hastie, Claire; Bush, William S.; Aldrich, Melinda C.; Crawford, Dana C.; Srivastava, Shiv; Cullen, Jennifer; Petrovics, Gyorgy; Casey, Graham; Wang, Ying; Tettey, Yao; Lachance, Joseph; Tang, Wei; Biritwum, Richard B.; Adjei, Andrew A.; Tay, Evelyn; Truelove, Ann; Niwa, Shelley; Yamoah, Kosj; Govindasami, Koveela; Chokkalingam, Anand P.; Keaton, Jacob M.; Hellwege, Jacklyn N.; Clark, Peter E.; Jalloh, Mohamed; Gueye, Serigne M.; Niang, Lamine; Ogunbiyi, Olufemi; Shittu, Olayiwola; Amodu, Olukemi; Adebiyi, Akindele O.; Aisuodionoe-Shadrach, Oseremen I.; Ajibola, Hafees O.; Jamda, Mustapha A.; Oluwole, Olabode P.; Nwegbu, Maxwell; Adusei, Ben; Mante, Sunny; Darkwa-Abrahams, Afua; Diop, Halimatou; Gundell, Susan M.; Roobol, Monique J.; Jenster, Guido; van Schaik, Ron H. N.; Hu, Jennifer J.; Sanderson, Maureen; Kachuri, Linda; Varma, Rohit; McKean-Cowdin, Roberta; Torres, Mina; Preuss, Michael H.; Loos, Ruth J. F.; Zawistowski, Matthew; Zollner, Sebastian; Lu, Zeyun; Van Den Eeden, Stephen K.; Easton, Douglas F.; Ambs, Stefan; Edwards, Todd L.; Magi, Reedik; Rebbeck, Timothy R.; Fritsche, Lars; Chanock, Stephen J.; Berndt, Sonja I.; Wiklund, Fredrik; Nakagawa, Hidewaki; Witte, John S.; Gaziano, J. Michael; Justice, Amy C.; Mancuso, Nick; Terao, Chikashi; Eeles, Rosalind A.; Kote-Jarai, Zsofia; Madduri, Ravi K.; Conti, David V.; Haiman, Christopher A. 分享 收藏
Genomic and Phenotypic Biomarkers for Precision Medicine Guidance in Advanced Prostate Cancer 晚期前列腺癌精准医学指导的基因组和表型生物标志物 Davoudi, Fatemeh; Moradi, Afshin; Becker, Therese M. M.; Lock, John G. G.; Abbey, Brian; Fontanarosa, Davide; Haworth, Annette; Clements, Judith; Ecker, Rupert C. C.; Batra, Jyotsna 分享 收藏
Evaluating approaches for constructing polygenic risk scores for prostate cancer in men of African and European ancestry 评估构建非洲和欧洲血统男性前列腺癌多基因风险评分的方法 Darst, Burcu F.; Shen, Jiayi; Madduri, Ravi K.; Rodriguez, Alexis A.; Xiao, Yukai; Sheng, Xin; Saunders, Edward J.; Dadaev, Tokhir; Brook, Mark N.; Hoffmann, Thomas J.; Muir, Kenneth; Wan, Peggy; Le Marchand, Loic; Wilkens, Lynne; Wang, Ying; Schleutker, Johanna; MacInnis, Robert J.; Cybulski, Cezary; Neal, David E.; Nordestgaard, Borge G.; Nielsen, Sune F.; Batra, Jyotsna; Clements, Judith A.; Gronberg, Henrik; Pashayan, Nora; Travis, Ruth C.; Park, Jong Y.; Albanes, Demetrius; Weinstein, Stephanie; Mucci, Lorelei A.; Hunter, David J.; Penney, Kathryn L.; Tangen, Catherine M.; Hamilton, Robert J.; Parent, Marie-Elise; Stanford, Janet L.; Koutros, Stella; Wolk, Alicja; Sorensen, Karina D.; Blot, William J.; Yeboah, Edward D.; Mensah, James E.; Lu, Yong-Jie; Schaid, Daniel J.; Thibodeau, Stephen N.; West, Catharine M.; Maier, Christiane; Kibel, Adam S.; Cancel-Tassin, Geraldine; Menegaux, Florence; John, Esther M.; Grindedal, Eli Marie; Khaw, Kay-Tee; Ingles, Sue A.; Vega, Ana; Rosenstein, Barry S.; Teixeira, Manuel R.; Kogevinas, Manoli; Cannon-Albright, Lisa; Huff, Chad; Multigner, Luc; Kaneva, Radka; Leach, Robin J.; Brenner, Hermann; Hsing, Ann W.; Kittles, Rick A.; Murphy, Adam B.; Logothetis, Christopher J.; Neuhausen, Susan L.; Isaacs, William B.; Nemesure, Barbara; Hennis, Anselm J.; Carpten, John; Pandha, Hardev; De Ruyck, Kim; Xu, Jianfeng; Razack, Azad; Teo, Soo-Hwang; Newcomb, Lisa F.; Fowke, Jay H.; Neslund-Dudas, Christine; Rybicki, Benjamin A.; Gamulin, Marija; Usmani, Nawaid; Claessens, Frank; Gago-Dominguez, Manuela; Castelao, Jose Esteban; Townsend, Paul A.; Crawford, Dana C.; Petrovics, Gyorgy; Casey, Graham; Roobol, Monique J.; Hu, Jennifer F.; Berndt, Sonja I.; van den Eeden, Stephen K.; Easton, Douglas F.; Chanock, Stephen J.; Cook, Michael B.; Wiklund, Fredrik; Witte, John S.; Eeles, Rosalind A.; Kote-Jarai, Zsofia; Watya, Stephen; Gaziano, John M.; Justice, Amy C.; Conti, David V.; Haiman, Christopher A. 分享 收藏
Characterisation of cell lines derived from prostate cancer patients with localised disease 来自患有局部疾病的前列腺癌患者的细胞系的表征 Moya, Leire; Walpole, Carina; Rae, Fiona; Srinivasan, Srilakshmi; Seim, Inge; Lai, John; Nicol, David; Williams, Elizabeth D.; Clements, Judith A.; Batra, Jyotsna 分享 收藏
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The roles of proteases in prostate cancer Koistinen, Hannu; Kovanen, Ruusu-Maaria; Hollenberg, Morley D.; Dufour, Antoine; Radisky, Evette S.; Stenman, Ulf-Hakan; Batra, Jyotsna; Clements, Judith; Hooper, John D.; Diamandis, Eleftherios; Schilling, Oliver; Rannikko, Antti; Mirtti, Tuomas 分享 收藏
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A humanized orthotopic tumor microenvironment alters the bone metastatic tropism of prostate cancer cells 人源化原位肿瘤微环境改变前列腺癌细胞的骨转移趋向性 McGovern, Jacqui A.; Bock, Nathalie; Shafiee, Abbas; Martine, Laure C.; Wagner, Ferdinand; Baldwin, Jeremy G.; Landgraf, Marietta; Lahr, Christoph A.; Meinert, Christoph; Williams, Elizabeth D.; Pollock, Pamela M.; Denham, Jim; Russell, Pamela J.; Risbridger, Gail P.; Clements, Judith A.; Loessner, Daniela; Holzapfel, Boris M.; Hutmacher, Dietmar W. 分享 收藏
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A Suite of Activity-Based Probes To Dissect the KLK Activome in Drug-Resistant Prostate Cancer 一套基于活性的探针，用于剖析耐药性前列腺癌中的KLK激活体 Lovell, Scott; Zhang, Leran; Kryza, Thomas; Neodo, Anna; Bock, Nathalie; De Vita, Elena; Williams, Elizabeth D.; Engelsberger, Elisabeth; Xu, Congyi; Bakker, Alexander T.; Maneiro, Maria; Tanaka, Reiko J.; Bevan, Charlotte L.; Clements, Judith A.; Tate, Edward W. 分享 收藏
A Genetic Risk Score to Personalize Prostate Cancer Screening, Applied to Population Data 个性化前列腺癌筛查的遗传风险评分，应用于人口数据 Huynh-Le, Minh-Phuong; Fan, Chun Chieh; Karunamuni, Roshan; Walsh, Eleanor, I; Turner, Emma L.; Lane, J. Athene; Martin, Richard M.; Neal, David E.; Donovan, Jenny L.; Hamdy, Freddie C.; Parsons, J. Kellogg; Eeles, Rosalind A.; Easton, Douglas F.; Kote-Jarai, Zsofia; Al Olama, Ali Amin; Garcia, Sara Benlloch; Muir, Kenneth; Gronberg, Henrik; Wiklund, Fredrik; Aly, Markus; Schleutker, Johanna; Sipeky, Csilla; Tammela, Teuvo L. J.; Nordestgaard, Borge Gronne; Key, Timothy J.; Travis, Ruth C.; Pharoah, Paul Dp; Pashayan, Nora; Khaw, Kay-Tee; Thibodeau, Stephen N.; McDonnell, Shannon K.; Schaid, Daniel J.; Maier, Christiane; Vogel, Walther; Luedeke, Manuel; Herkommer, Kathleen; Kibel, Adam S.; Cybulski, Cezary; Wokolorczyk, Dominika; Kluzniak, Wojciech; Cannon-Albright, Lisa A.; Brenner, Hermann; Ben Schoettker; Holleczek, Bernd; Park, Jong Y.; Sellers, Thomas A.; Lin, Hui-Yi; Slavov, Chavdar Kroumov; Kaneva, Radka P.; Mitev, Vanio, I; Batra, Jyotsna; Clements, Judith A.; Spurdle, Amanda B.; Teixeira, Manuel R.; Paulo, Paula; Maia, Sofia; Pandha, Hardev; Michael, Agnieszka; Mills, Ian G.; Andreassen, Ole A.; Dale, Anders M.; Seibert, Tyler M. 分享 收藏
An integrative multi-omics analysis to identify candidate DNA methylation biomarkers related to prostate cancer risk Wu, Lang; Yang, Yaohua; Guo, Xingyi; Shu, Xiao-Ou; Cai, Qiuyin; Shu, Xiang; Li, Bingshan; Tao, Ran; Wu, Chong; Nikas, Jason B.; Sun, Yanfa; Zhu, Jingjing; Roobol, Monique J.; Giles, Graham G.; Brenner, Hermann; John, Esther M.; Clements, Judith; Grindedal, Eli Marie; Park, Jong Y.; Stanford, Janet L.; Kote-Jarai, Zsofia; Haiman, Christopher A.; Eeles, Rosalind A.; Zheng, Wei 分享 收藏
The effect of sample size on polygenic hazard models for prostate cancer 样本量对前列腺癌多基因风险模型的影响 Karunamuni, Roshan A.; Huynh-Le, Minh-Phuong; Fan, Chun C.; Eeles, Rosalind A.; Easton, Douglas F.; Kote-Jarai, Zsofia; Al Olama, Ali Amin; Garcia, Sara Benlloch; Muir, Kenneth; Gronberg, Henrik; Wiklund, Fredrik; Aly, Markus; Schleutker, Johanna; Sipeky, Csilla; Tammela, Teuvo L. J.; Nordestgaard, Borge G.; Key, Tim J.; Travis, Ruth C.; Neal, David E.; Donovan, Jenny L.; Hamdy, Freddie C.; Pharoah, Paul; Pashayan, Nora; Khaw, Kay-Tee; Thibodeau, Stephen N.; McDonnell, Shannon K.; Schaid, Daniel J.; Maier, Christiane; Vogel, Walther; Luedeke, Manuel; Herkommer, Kathleen; Kibel, Adam S.; Cybulski, Cezary; Wokolorczyk, Dominika; Kluzniak, Wojciech; Cannon-Albright, Lisa; Brenner, Hermann; Ben Schoettker; Holleczek, Bernd; Park, Jong Y.; Sellers, Thomas A.; Lin, Hui-Yi; Slavov, Chavdar; Kaneva, Radka; Mitev, Vanio; Batra, Jyotsna; Clements, Judith A.; Spurdle, Amanda; Teixeira, Manuel R.; Paulo, Paula; Maia, Sofia; Pandha, Hardev; Michael, Agnieszka; Mills, Ian G.; Andreassen, Ole A.; Dale, Anders M.; Seibert, Tyler M. 分享 收藏
The molecular function of kallikrein-related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer Kryza, Thomas; Bock, Nathalie; Lovell, Scott; Rockstroh, Anja; Lehman, Melanie L.; Lesner, Adam; Panchadsaram, Janaththani; Silva, Lakmali Munasinghage; Srinivasan, Srilakshmi; Snell, Cameron E.; Williams, Elizabeth D.; Fazli, Ladan; Gleave, Martin; Batra, Jyotsna; Nelson, Colleen; Tate, Edward W.; Harris, Jonathan; Hooper, John D.; Clements, Judith A. 分享 收藏
Microenvironment engineering of osteoblastic bone metastases reveals osteomimicry of patient-derived prostate cancer xenografts Shokoohmand, Ali; Ren, Jiongyu; Baldwin, Jeremy; Atack, Anthony; Shafiee, Abbas; Theodoropoulos, Christina; Wille, Marie-Luise; Tran, Phong A.; Bray, Laura J.; Smith, Deborah; Chetty, Naven; Pollock, Pamela M.; Hutmacher, Dietmar W.; Clements, Judith A.; Williams, Elizabeth D.; Bock, Nathalie 分享 收藏
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