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Integrating Single-Cell Transcriptome-Wide Mendelian Randomization and Differentially Expressed Gene Analyses to Prioritize Dynamic Immune-Related Drug Targets for Cancers 整合单细胞转录组范围的孟德尔随机化和差异表达基因分析，以优先考虑癌症的动态免疫相关药物靶标 Zheng, Jie; Yang, Qian; Liu, Haoyu; Zhao, Huiling; Wang, Shuangyuan; Liu, Yi; Wu, Xueyan; Ding, Yilan; Ying, Hui; Ye, Youqiu; Huang, Xi; Ye, Lei; Zheng, Ruizhi; Lin, Hong; Li, Mian; Wang, Tiange; Zhao, Zhiyun; Xu, Min; Duan, Yi; Guo, Hao; Yuan, Zhongshang; Haycock, Philip; Davey Smith, George; Martin, Richard M.; Ning, Guang; Hu, Fang; Wang, Weiqing; Gaunt, Tom R.; Lu, Jieli; Bi, Yufang 分享 收藏
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Transcriptome-wide Mendelian randomization during CD4+ T cell activation reveals immune-related drug targets for cardiometabolic diseases Wu, Xueyan; Ying, Hui; Yang, Qianqian; Yang, Qian; Liu, Haoyu; Ding, Yilan; Zhao, Huiling; Chen, Zhihe; Zheng, Ruizhi; Lin, Hong; Wang, Shuangyuan; Li, Mian; Wang, Tiange; Zhao, Zhiyun; Xu, Min; Chen, Yuhong; Xu, Yu; Vincent, Emma E.; Borges, Maria Carolina; Gaunt, Tom R.; Ning, Guang; Wang, Weiqing; Bi, Yufang; Zheng, Jie; Lu, Jieli 分享 收藏
Protein Identification for Stroke Progression via Mendelian Randomization in Million Veteran Program and UK Biobank 在百万退伍军人计划和英国生物银行中通过孟德尔随机化鉴定中风进展的蛋白质 Elmore, Andrew R.; Adhikari, Nimish; Hartley, April E.; Aparicio, Hugo Javier; Posner, Daniel C.; Hemani, Gibran; Tilling, Kate; Gaunt, Tom R.; Wilson, Peter W. F.; Casas, Juan P.; Gaziano, John Michael; Davey Smith, George; Paternoster, Lavinia; Cho, Kelly; Peloso, Gina M. 分享 收藏
The effect of SGLT2 inhibition on prostate cancer Mendelian randomization and observational analysis using electronic healthcare and cohort data SGLT2抑制对前列腺癌的影响使用电子医疗保健和队列数据进行孟德尔随机化和观察分析 Zheng, Jie; Lu, Jieli; Qi, Jiying; Yang, Qian; Zhao, Huiling; Liu, Haoyu; Chen, Zhihe; Huang, Lanhui; Ye, Youqiong; Xu, Min; Xu, Yu; Wang, Tiange; Li, Mian; Zhao, Zhiyun; Zheng, Ruizhi; Wang, Shuangyuan; Lin, Hong; Hu, Chunyan; Chui, Celine Sze Ling; Yeung, Shiu Lun Au; Luo, Shan; Dimopoulou, Olympia; Dixon, Padraig; Harrison, Sean; Liu, Yi; Robinson, Jamie; Yarmolinsky, James; Haycock, Philip; Yuan, Jinqiu; Lewis, Sarah; Yuan, Zhongshang; Gaunt, Tom R.; Smith, George Davey; Ning, Guang; Martin, Richard M.; Cui, Bin; Wang, Weiqing; Bi, Yufang 分享 收藏
Causal relationships between anthropometric traits, bone mineral density, osteoarthritis and spinal stenosis: A Mendelian randomisation investigation Sobczyk, Maria K.; Faber, Benjamin G.; Southam, Lorraine; Frysz, Monika; Hartley, April; Zeggini, Eleftheria; Tang, Haotian; Gaunt, Tom R. 分享 收藏
Efficacy of metformin targets on cardiometabolic health in the general population and non-diabetic individuals: a Mendelian randomization study Zheng, Jie; Xu, Min; Yang, Qian; Hu, Chunyan; Walker, Venezia; Lu, Jieli; Wang, Jiqiu; Liu, Ruixin; Xu, Yu; Wang, Tiange; Zhao, Zhiyun; Yuan, Jinqiu; Burgess, Stephen; Yeung, Shiu Lun Au; Luo, Shan; Anderson, Emma L.; V. Holmes, Michael; Smith, George Davey; Ning, Guang; Wang, Weiqing; Gaunt, Tom R.; Bi, Yufang 分享 收藏
Triangulating evidence from observational and Mendelian randomization studies of ketone bodies for cognitive performance 来自酮体认知表现的观察性和孟德尔随机化研究的三角测量证据 Sae-jie, Wichanon; Supasai, Suangsuda; Kivimaki, Mika; Price, Jackie F.; Wong, Andrew; Kumari, Meena; Engmann, Jorgen; Shah, Tina; Schmidt, Amand F.; Gaunt, Tom R.; Hingorani, Aroon; Charoen, Pimphen 分享 收藏
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The association between genetically elevated polyunsaturated fatty acids and risk of cancer 遗传升高的多不饱和脂肪酸与癌症风险之间的关联 Haycock, Philip C.; Borges, Maria Carolina; Burrows, Kimberley; Lemaitre, Rozenn N.; Burgess, Stephen; Khankari, Nikhil K.; Tsilidis, Konstantinos K.; Gaunt, Tom R.; Hemani, Gibran; Zheng, Jie; Truong, Therese; Birmann, Brenda M.; OMara, Tracy; Spurdle, Amanda B.; Iles, Mark M.; Law, Matthew H.; Slager, Susan L.; Hosnijeh, Fatemeh Saberi; Mariosa, Daniela; Cotterchio, Michelle; Cerhan, James R.; Peters, Ulrike; Enroth, Stefan; Gharahkhani, Puya; Le Marchand, Loic; Williams, Ann C.; Block, Robert C.; Amos, Christopher I.; Hung, Rayjean J.; Zheng, Wei; Gunter, Marc J.; Smith, George Davey; Relton, Caroline; Martin, Richard M. 分享 收藏
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Linking Physical Activity to Breast Cancer via Inflammation, Part 2: The Effect of Inflammation on Breast Cancer Risk 通过炎症将身体活动与乳腺癌联系起来，第2部分: 炎症对乳腺癌风险的影响 Lou, Makayla W. C.; Drummond, Ann E.; Swain, Christopher T. V.; Milne, Roger L.; English, Dallas R.; Brown, Kristy A.; van Roekel, Eline H.; Skinner, Tina L.; Moore, Melissa M.; Gaunt, Tom R.; Martin, Richard M.; Lewis, Sarah J.; Lynch, Brigid M. 分享 收藏
Linking Physical Activity to Breast Cancer Risk via Inflammation, Part 1: The Effect of Physical Activity on Inflammation 通过炎症将身体活动与乳腺癌风险联系起来，第1部分: 身体活动对炎症的影响 Swain, Christopher T. V.; Drummond, Ann E.; Milne, Roger L.; English, Dallas R.; Brown, Kristy A.; Lou, Makayla W. C.; Boing, Leonessa; Bageley, Amy; Skinner, Tina L.; van Roekel, Eline H.; Moore, Melissa M.; Gaunt, Tom R.; Martin, Richard M.; Lewis, Sarah J.; Lynch, Brigid M. 分享 收藏
Brain expression quantitative trait locus and network analyses reveal downstream effects and putative drivers for brain-related diseases 脑表达数量性状基因座和网络分析揭示了脑相关疾病的下游效应和推定驱动因素 de Klein, Niek; Tsai, Ellen A.; Vochteloo, Martijn; Baird, Denis; Huang, Yunfeng; Chen, Chia-Yen; van Dam, Sipko; Oelen, Roy; Deelen, Patrick; Bakker, Olivier B.; El Garwany, Omar; Ouyang, Zhengyu; Marshall, Eric E.; Zavodszky, Maria I.; van Rheenen, Wouter; Bakker, Mark K.; Veldink, Jan; Gaunt, Tom R.; Runz, Heiko; Franke, Lude; Westra, Harm-Jan 分享 收藏
Causal effects of maternal circulating amino acids on offspring birthweight: a Mendelian randomisation study 母体循环氨基酸对后代出生体重的因果影响: 孟德尔随机化研究 Zhao, Jian; Stewart, Isobel D.; Baird, Denis; Mason, Dan; Wright, John; Zheng, Jie; Gaunt, Tom R.; Evans, David M.; Freathy, Rachel M.; Langenberg, Claudia; Warrington, Nicole M.; Lawlor, Deborah A.; Borges, Maria Carolina 分享 收藏
Biomedical consequences of elevated cholesterol-containing lipoproteins and apolipoproteins on cardiovascular and non-cardiovascular outcomes 含胆固醇的脂蛋白和载脂蛋白升高对心血管和非心血管结局的生物医学后果 Schmidt, Amand F.; Joshi, Roshni; Gordillo-Maranon, Maria; Drenos, Fotios; Charoen, Pimphen; Giambartolomei, Claudia; Bis, Joshua C.; Gaunt, Tom R.; Hughes, Alun D.; Lawlor, Deborah A.; Wong, Andrew; Price, Jackie F.; Chaturvedi, Nishi; Wannamethee, Goya; Franceschini, Nora; Kivimaki, Mika; Hingorani, Aroon D.; Finan, Chris 分享 收藏
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