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A

Akseli Hemminki

helsinki university hospital
H指数:77
被引数:2.8万

个人简介

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教育背景

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工作经历

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荣誉奖项

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Alistipes and Eggerthella shape the response to oncolytic adenovirus therapy in mice and humans through short-chain fatty acid metabolism

阿利斯特普斯菌和艾格特埃拉菌通过短链脂肪酸代谢塑造小鼠和人类对溶瘤腺病毒治疗的反应

OncoImmunology
IF6.3
2026-04-090
OA
Mirte van der Heijden; James Hugo Armstrong Clubb; Pande Putu Erawijantari; Aki Ronkainen; Victor Arias; Elise Jirovec; Tatiana Kudling; Santeri Artturi Pakola; Nea Ojala; Lyna Haybout; Saru Basnet; Susanna Grönberg-Vähä-Koskela; Sini Karoliina Raatikainen; Otto Hemminki; Anna Kanerva; Dafne Carolina Alves Quixabeira; Victor Cervera-Carrascon; João Manuel dos Santos; Leo Lahti; Akseli Hemminki
Single intravenous administration of oncolytic adenovirus TILT-123 results in systemic tumor transduction and immune response in patients with advanced solid tumors

单次静脉注射溶瘤腺病毒TILT-123可导致晚期实体瘤患者的全身肿瘤转导和免疫反应

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
IF12.8
2024-11-060
OAAI
Jirovec, Elise; Quixabeira, Dafne C. A.; Clubb, James H. A.; Pakola, Santeri A.; Kudling, Tatiana; Arias, Victor; Haybout, Lyna; Jalkanen, Katriina; Alanko, Tuomo; Monberg, Tine; Khammari, Amir; Dreno, Brigitte; Svane, Inge Marie; Block, Matthew S.; Adamo, Daniel A.; Maenpaa, Johanna; Kistler, Claudia; Sorsa, Suvi; Hemminki, Otto; Kanerva, Anna; Santos, Joao M.; Cervera-Carrascon, Victor; Hemminki, Akseli
Overcoming effector T cell exhaustion in ovarian cancer ascites with a novel adenovirus encoding for a MUC1 bispecific antibody engager and IL-2 cytokine

用编码MUC1双特异性抗体接合器和IL-2细胞因子的新型腺病毒克服卵巢癌腹水中的效应T细胞耗竭

MOLECULAR THERAPY
IF12
2024-09-012
OAAI
Basnet, Saru; Van der Heijden, Mirte; Quixabeira, Dafne C. A.; Jirovec, Elise; Gronberg-Vaha-Koskela, Susanna A. M.; Clubb, James H. A.; Kanerva, Anna; Pakola, Santeri; Haybout, Lyna; Arias, Victor; Hemminki, Otto; Kudling, Tatiana; Zafar, Sadia; Cervera-Carrascon, Victor; Santos, Joao M.; Hemminki, Akseli
Overcoming effector T cell exhaustion in ovarian cancer ascites with a novel adenovirus encoding for a MUC1 bispecific antibody engager and IL-2 cytokine (vol 32, 10.1016/j.ymthe.2024.06.029, 2024)
MOLECULAR THERAPY
IF12
2024-08-010
OAAI
Basnet, Saru; Van der Heijden, Mirte; Quixabeira, Dafne C. A.; Jirovec, Elise; Gronberg-Vaha-Koskela, Susanna A. M.; Clubb, James H. A.; Kanerva, Anna; Pakola, Santeri; Haybout, Lyna; Arias, Victor; Hemminki, Otto; Kudling, Tatiana; Zafar, Sadia; Cervera-Carrascon, Victor; Santos, Joao M.; Hemminki, Akseli
Safety, Efficacy, and Biological Data of T-Cell-Enabling Oncolytic Adenovirus TILT-123 in Advanced Solid Cancers from the TUNIMO Monotherapy Phase I Trial

TUNIMO单药治疗I期试验的晚期实体癌中T细胞使溶瘤腺病毒TILT-123的安全性，有效性和生物学数据

CLINICAL CANCER RESEARCH
IF10.2
2024-03-274
OAAI
Pakola, Santeri A.; Peltola, Katriina J.; Clubb, James H. A.; Jirovec, Elise; Haybout, Lyna; Kudling, Tatiana V.; Alanko, Tuomo; Korpisaari, Riitta; Juteau, Susanna; Jaakkola, Marjut; Sormunen, Jorma; Kemppainen, Jukka; Hemmes, Annabrita; Pellinen, Teijo; van der Heijden, Mirte; Quixabeira, Dafne C. A.; Kistler, Claudia; Sorsa, Suvi; Havunen, Riikka; Santos, Joao M.; Cervera-Carrascon, Victor; Hemminki, Akseli
Effective intravenous delivery of adenovirus armed with TNFα and IL-2 improves anti-PD-1 checkpoint blockade in non-small cell lung cancer

有效静脉注射tnf α 和IL-2腺病毒可改善非小细胞肺癌的anti-PD-1检查点阻滞

ONCOIMMUNOLOGY
IF6.3
2023-08-0211
OA
Kudling, Tatiana V.; Clubb, James H. A.; Pakola, Santeri; Quixabeira, Dafne C. A.; Lahdeniemi, Iris A. K.; Heinio, Camilla; Arias, Victor; Havunen, Riikka; Cervera-Carrascon, Victor; Santos, Joao M.; Sutinen, Eva; Raesaenen, Jari; Borenius, Kristian; Mayranpaa, Mikko I.; Aaltonen, Eero; Sorsa, Suvi; Hemminki, Otto; Kanerva, Anna; Verschuren, Emmy W.; Ilonen, Ilkka; Hemminki, Akseli
An oncolytic adenovirus coding for a variant interleukin 2 cytokine improves response to chemotherapy through enhancement of effector lymphocyte cytotoxicity, fibroblast compartment modulation and mitotic slippage

编码变异白介素2细胞因子的溶瘤腺病毒通过增强效应淋巴细胞的细胞毒性，成纤维细胞隔室调节和有丝分裂滑移来改善对化学疗法的反应

FRONTIERS IN IMMUNOLOGY
IF5.9
2023-07-053
OAAI
Pakola, Santeri; Quixabeira, Dafne C. A.; Kudling, Tatiana V.; Clubb, James H. A.; Gronberg-Vaha-Koskela, Susanna; Basnet, Saru; Jirovec, Elise; Arias, Victor; Haybout, Lyna; Heinioe, Camilla; Santos, Joao M.; Cervera-Carrascon, Victor; Havunen, Riikka; Anttila, Marjukka; Hemminki, Akseli

研究方向

暂未获取到该数据
A
Anna Kanerva
H 指数:46论文数:310被引数:6,775
K
Kari Hemminki
H 指数:107论文数:1,397被引数:5.5万
O
Otto Hemminki
H 指数:23论文数:118被引数:2,076
R
Riikka Havunen
H 指数:22论文数:113被引数:1,569
V
Vincenzo Cerullo
H 指数:48论文数:336被引数:7,136
A
Asta Försti
H 指数:57论文数:509被引数:1.5万
J
João M. Santos
H 指数:21论文数:100被引数:1,514
T
Timo Joensuu
H 指数:26论文数:75被引数:2,355
J
Jan Sundquist
H 指数:92论文数:1,146被引数:4.0万
V
Víctor Cervera-Carrascón
H 指数:22论文数:106被引数:1,139