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D

David E. Levy

New York University
H指数:124
被引数:5.3万

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工作经历

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荣誉奖项

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Mitochondrial dysfunction induced by a SH2 domain-targeting STAT3 inhibitor leads to metabolic synthetic lethality in cancer cells

靶向SH2结构域的STAT3抑制剂诱导的线粒体功能障碍导致癌细胞的代谢合成致死率

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2017-06-0588
OAAI
Genini, Davide; Brambilla, Lara; Laurini, Erik; Merulla, Jessica; Civenni, Gianluca; Pandit, Shusil; D'Antuono, Rocco; Perez, Laurent; Levy, David E.; Pricl, Sabrina; Carbone, Giuseppina M.; Catapano, Carlo V.
The kinase TBK1 functions in dendritic cells to regulate T cell homeostasis, autoimmunity, and antitumor immunity

激酶TBK1在树突状细胞中起调节T细胞稳态，自身免疫和抗肿瘤免疫的作用

JOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
2017-03-2975
OAAI
Xiao, Yichuan; Zou, Qiang; Xie, Xiaoping; Liu, Ting; Li, Haiyan S.; Jie, Zuliang; Jin, Jin; Hu, Hongbo; Manyam, Ganiraju; Zhang, Li; Cheng, Xuhong; Wang, Hui; Marie, Isabelle; Levy, David E.; Watowich, Stephanie S.; Sun, Shao-Cong
Insertional Mutagenesis Identifies a STAT3/Arid1b/β-catenin Pathway Driving Neurofibroma Initiation
CELL REPORTS
IF6.9
2016-03-0158
OAAI
Wu, Jianqiang; Keng, Vincent W.; Patmore, Deanna M.; Kendall, Jed J.; Patel, Ami V.; Jousma, Edwin; Jessen, Walter J.; Choi, Kwangmin; Tschida, Barbara R.; Silverstein, Kevin A. T.; Fan, Danhua; Schwartz, Eric B.; Fuchs, James R.; Zou, Yuanshu; Kim, Mi-Ok; Dombi, Eva; Levy, David E.; Huang, Gang; Cancelas, Jose A.; Stemmer-Rachamimov, Anat O.; Spinner, Robert J.; Largaespada, David A.; Ratner, Nancy
Loss of IL-6/Stat3 signalling drives metastatic prostate cancer in mice and men
CYTOKINE
IF3.7
2015-11-010
PREAI
Pencik, Jan; Schlederer, Michaela; Gruber, Wolfgang; Unger, Christine; Walker, Steven M.; Chalaris, Athena; Marie, Isabelle; Hassler, Melanie R.; Javaheri, Tahereh; Aksoy, Osman; Blayney, Jaine K.; Mazal, Peter; Grebien, Florian; Egger, Gerda; Poli, Valeria; Eferl, Robert; Kennedy, Richard; Fend, Falko; Scharpf, Marcus; Braun, Martin; Perner, Sven; Levy, David E.; Malcolm, Tim; Turner, Suzanne D.; Haitel, Andrea; Susani, Martin; Moazzami, Ali; Rose-Johns, Stefan; Aberger, Fritz; Merkel, Olaf; Moriggl, Richard; Culig, Zoran; Dolznig, Helmut; Kenner, Lukas
STAT3 regulated ARF expression suppresses prostate cancer metastasis
NATURE COMMUNICATIONS
IF15.7
2015-07-22141
OAAI
Pencik, Jan; Schlederer, Michaela; Gruber, Wolfgang; Unger, Christine; Walker, Steven M.; Chalaris, Athena; Marie, Isabelle J.; Hassler, Melanie R.; Javaheri, Tahereh; Aksoy, Osman; Blayney, Jaine K.; Prutsch, Nicole; Skucha, Anna; Herac, Merima; Kraemer, Oliver H.; Mazal, Peter; Grebien, Florian; Egger, Gerda; Poli, Valeria; Mikulits, Wolfgang; Eferl, Robert; Esterbauer, Harald; Kennedy, Richard; Fend, Falko; Scharpf, Marcus; Braun, Martin; Perner, Sven; Levy, David E.; Malcolm, Tim; Turner, Suzanne D.; Haitel, Andrea; Susani, Martin; Moazzami, Ali; Rose-John, Stefan; Aberger, Fritz; Merkel, Olaf; Moriggl, Richard; Culig, Zoran; Dolznig, Helmut; Kenner, Lukas

研究方向

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I
Isabelle Marié
H 指数:37论文数:177被引数:5,834
D
Daniel J. Gough
H 指数:31论文数:78被引数:4,712
王
王亚明
H 指数:76论文数:662被引数:2.6万
V
Valeria Poli
H 指数:76论文数:261被引数:2.2万
L
Lara Brambilla
H 指数:7论文数:16被引数:400
W
Warren J. Leonard
H 指数:128论文数:549被引数:6.0万
B
Beatriz M. A. Fontoura
H 指数:40论文数:84被引数:5,972
M
Mark H. Kaplan
H 指数:93论文数:666被引数:3.7万
R
Ricky W. Johnstone
H 指数:96论文数:780被引数:3.8万
F
Falko Fend
H 指数:71论文数:757被引数:2.0万