Paul J.R. Barton - Publications, H-index & Citations

Paul J.R. Barton

National Heart and Lung Institute

71H指数

316论文数

1.7W被引数

收录论文 84

发表时间

Pangenomes aid accurate detection of large insertions and deletions from targeted sequencing: the case of cardiomyopathies 泛基因组有助于从靶向测序中准确检测大片段插入和缺失：心肌病案例

Genome Medicine

IF11.2

2026-08-26

OAAI

Francesco Mazzarotto; Özem Kalay; Elif Arslan; Valeria Cinquina; Rachel J. Buchan; Valeria Bertini; Esmé Cavanagh; Deniz Turgut; Mona Allouba; Alaa Afify; Sarah Halawa; Pantazis Theotokis; Gungor Budak; Francesca Girolami; Alessia Azzu; Petra Peldova; Nik Matthews; Dudley J. Pennell; Jiri Bonaventura; Iacopo Olivotto; Elisabetta Pelo; Marina Colombi; Milan Macek; Paul J. R. Barton; Yasmine Aguib; Magdi Yacoub; Marco Ritelli; Massimo Gennarelli; H. Serhat Tetikol; Roddy Walsh; James S. Ware; Amit Jain

Choice of cell-delivery route for skeletal myoblast transplantation for treating post-infarction chronic heart failure in rat (vol 3, e3071, 2008)选择骨骼肌成肌细胞移植治疗大鼠心肌梗死后慢性心力衰竭的细胞递送途径（vol 3, e3071, 2008）

PLoS One

IF2.6

2026-05-05

OAAI

Fukushima, Satsuki; Coppen, Steven R.; Lee, Joon; Yamahara, Kenichi; Felkin, Leanne E.; Terracciano, Cesare M. N.; Barton, Paul J. R.; Yacoub, Magdi H.; Suzuki, Ken

Sex Differences in the Genetic Causes of Dilated Cardiomyopathy 扩张型心肌病的遗传病因中的性别差异

Journal of the American College of Cardiology

IF22.3

2025-07-28

PREAI

Massimo Mangino; Kathryn A. McGurk; Pantazis Theotokis; Rachel J. Buchan; Clare R. Stockwell; Prisca K. Thami; Emma Jennings; Elaine Wan; Catherine Enright; Ahmed Adlan; Tamim Akbari; John Baksi; Paul J.R. Barton; Colin Berry; Gerry Carr-White; Amedeo Chiribiri; Rob Cooper; Abhishek Dattani; Andrew S. Flett; Roy S. Gardner; John P. Greenwood; Brian P. Halliday; Daniel J. Hammersley; David C. Hutchings; Masliza Mahmod; Benjamin Marrow; Gerry P. McCann; Manish Motwani; Stefan Neubauer; Declan P. O’ Regan; Stephen P. Page; Antonis Pantazis; Charles Peebles; Betty Raman; Peter P. Swoboda; Amanda Varnava; Luigi Venetucci; Hugh Watkins; David Wright; Sanjay K. Prasad; Stuart A. Cook; James S. Ware; Upasana (Paz) Tayal

Biallelic Loss of Function Variants in Myocardial Zonula Adherens Protein Gene (MYZAP) Cause a Severe Recessive Form of Dilated Cardiomyopathy

jacc heart failure

IF8.4

2024-03-01

OAAI

Ochoa, Juan Pablo; Lalaguna, Laura; Mirelis, Jesus G.; Dominguez, Fernando; Gonzalez-Lopez, Esther; Salas, Clara; Roustan, Gaston; Mcgurk, Kathryn A.; Zheng, Sean L.; Barton, Paul J. R.; Ware, James S.; Gomez-Gaviro, Maria Victoria; Lara-Pezzi, Enrique; Garcia-Pavia, Pablo

The penetrance of rare variants in cardiomyopathy-associated genes: A cross-sectional approach to estimating penetrance for secondary findings

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2023-09-01

OAAI

Mcgurk, Kathryn A.; Zhang, Xiaolei; Theotokis, Pantazis; Thomson, Kate; Harper, Andrew; Buchan, Rachel J.; Mazaika, Erica; Ormondroyd, Elizabeth; Wright, William T.; Macaya, Daniela; Pua, Chee Jian; Funke, Birgit; Macarthur, Daniel G.; Prasad, Sanjay K.; Cook, Stuart A.; Allouba, Mona; Aguib, Yasmine; Yacoub, Magdi H.; O'Regan, Declan P.; Barton, Paul J. R.; Watkins, Hugh; Bottolo, Leonardo; Ware, James S.

Ethnicity, consanguinity, and genetic architecture of hypertrophic cardiomyopathy 肥厚性心肌病的种族，血缘和遗传结构

EUROPEAN HEART JOURNAL

IF35.6

2023-07-11

OAAI

Allouba, Mona; Walsh, Roddy; Afify, Alaa; Hosny, Mohammed; Halawa, Sarah; Galal, Aya; Fathy, Mariam; Theotokis, Pantazis, I; Boraey, Ahmed; Ellithy, Amany; Buchan, Rachel; Govind, Risha; Whiffin, Nicola; Anwer, Shehab; ElGuindy, Ahmed; Ware, James S.; Barton, Paul J. R.; Yacoub, Magdi; Aguib, Yasmine

Genetic Architecture of Acute Myocarditis and the Overlap With Inherited Cardiomyopathy

CIRCULATION

IF38.6

2022-10-11

OAAI

Lota, Amrit S.; Hazebroek, Mark R.; Theotokis, Pantazis; Wassall, Rebecca; Salmi, Sara; Halliday, Brian P.; Tayal, Upasana; Verdonschot, Job; Meena, Devendra; Owen, Ruth; de Marvao, Antonio; Iacob, Alma; Yazdani, Momina; Hammersley, Daniel J.; Jones, Richard E.; Wage, Riccardo; Buchan, Rachel; Vivian, Fredrik; Hafouda, Yakeen; Noseda, Michela; Gregson, John; Mittal, Tarun; Wong, Joyce; Robertus, Jan Lukas; Baksi, A. John; Vassiliou, Vassilios; Tzoulaki, Ioanna; Pantazis, Antonis; Cleland, John G. F.; Barton, Paul J. R.; Cook, Stuart A.; Pennell, Dudley J.; Garcia-Pavia, Pablo; Cooper, Leslie T., Jr.; Heymans, Stephane; Ware, James S.; Prasad, Sanjay K.

Contribution of Noncanonical Splice Variants to TTN Truncating Variant Cardiomyopathy

CIRCULATION-GENOMIC AND PRECISION MEDICINE

IF5.5

2021-10-01

OAAI

Patel, Parth N.; Ito, Kaoru; Willcox, Jon A. L.; Haghighi, Alireza; Jang, Min Young; Gorham, Joshua M.; DePalma, Steven R.; Lam, Lien; McDonough, Barbara; Johnson, Renee; Lakdawala, Neal K.; Roberts, Amy; Barton, Paul J. R.; Cook, Stuart A.; Fatkin, Diane; Seidman, Christine E.; Seidman, J. G.

New Variant With a Previously Unrecognized Mechanism of Pathogenicity in Hypertrophic Cardiomyopathy

CIRCULATION

IF38.6

2021-08-31

OAAI

Aguib, Yasmine; Allouba, Mona; Walsh, Roddy; Ibrahim, Ayman M.; Halawa, Sarah; Afify, Alaa; Hosny, Mohammed; Theotokis, Pantazis I.; Galal, Aya; Elshorbagy, Sara; Roshdy, Mohamed; Kassem, Heba S.; Ellithy, Amany; Buchan, Rachel; Whiffin, Nicola; Anwer, Shehab; Cook, Stuart A.; Moustafa, Ahmed; ElGuindy, Ahmed; Ware, James S.; Barton, Paul J. R.; Yacoub, Magdi

Moderate excess alcohol consumption and adverse cardiac remodelling in dilated cardiomyopathy

HEART

IF4.4

2021-08-11

OAAI

Tayal, Upasana; Gregson, John; Buchan, Rachel; Whiffin, Nicola; Halliday, Brian P.; Lota, Amrit; Roberts, Angharad M.; Baksi, A. John; Voges, Inga; Jarman, Julian W. E.; Baruah, Resham; Frenneaux, Michael; Cleland, John G. F.; Barton, Paul; Pennell, Dudley J.; Ware, James S.; Cook, Stuart A.; Prasad, Sanjay K.

Non-coding region variants upstream of MEF2C cause severe developmental disorder through three distinct loss-of-function mechanisms MEF2C上游的非编码区变异通过三种不同的功能丧失机制导致严重的发育障碍

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2021-06-01

OAAI

Wright, Caroline F.; Quaife, Nicholas M.; Ramos-Hernandez, Laura; Danecek, Petr; Ferla, Matteo P.; Samocha, Kaitlin E.; Kaplanis, Joanna; Gardner, Eugene J.; Eberhardt, Ruth Y.; Chao, Katherine R.; Karczewski, Konrad J.; Morales, Joannella; Gallone, Giuseppe; Balasubramanian, Meena; Banka, Siddharth; Gompertz, Lianne; Kerr, Bronwyn; Kirby, Amelia; Lynch, Sally A.; Morton, Jenny E., V; Pinz, Hailey; Sansbury, Francis H.; Stewart, Helen; Zuccarelli, Britton D.; Cook, Stuart A.; Taylor, Jenny C.; Juusola, Jane; Retterer, Kyle; Firth, Helen, V; Hurles, Matthew E.; Lara-Pezzi, Enrique; Barton, Paul J. R.; Whiffin, Nicola

Systematic large-scale assessment of the genetic architecture of left ventricular noncompaction reveals diverse etiologies

GENETICS IN MEDICINE

IF6.2

2021-05-01

OAAI

Mazzarotto, Francesco; Hawley, Megan H.; Beltrami, Matteo; Beekman, Leander; de Marvao, Antonio; McGurk, Kathryn A.; Statton, Ben; Boschi, Beatrice; Girolami, Francesca; Roberts, Angharad M.; Lodder, Elisabeth M.; Allouba, Mona; Romeih, Soha; Aguib, Yasmine; Baksi, A. John; Pantazis, Antonis; Prasad, Sanjay K.; Cerbai, Elisabetta; Yacoub, Magdi H.; O'Regan, Declan P.; Cook, Stuart A.; Ware, James S.; Funke, Birgit; Olivotto, Iacopo; Bezzina, Connie R.; Barton, Paul J. R.; Walsh, Roddy

Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect

NATURE GENETICS

IF31.8

2021-01-25

156

OAAI

Tadros, Rafik; Francis, Catherine; Xu, Xiao; Vermeer, Alexa M. C.; Harper, Andrew R.; Huurman, Roy; Bisabu, Ken Kelu; Walsh, Roddy; Hoorntje, Edgar T.; te Rijdt, Wouter P.; Buchan, Rachel J.; van Velzen, Hannah G.; van Slegtenhorst, Marjon A.; Vermeulen, Jentien M.; Offerhaus, Joost Allard; Bai, Wenjia; de Marvao, Antonio; Lahrouchi, Najim; Beekman, Leander; Karper, Jacco C.; Veldink, Jan H.; Kayvanpour, Elham; Pantazis, Antonis; Baksi, A. John; Whiffin, Nicola; Mazzarotto, Francesco; Sloane, Geraldine; Suzuki, Hideaki; Schneider-Luftman, Deborah; Elliott, Paul; Richard, Pascale; Ader, Flavie; Villard, Eric; Lichtner, Peter; Meitinger, Thomas; Tanck, Michael W. T.; van Tintelen, J. Peter; Thain, Andrew; McCarty, David; Hegele, Robert A.; Roberts, Jason D.; Amyot, Julie; Dube, Marie-Pierre; Cadrin-Tourigny, Julia; Giraldeau, Genevieve; L'Allier, Philippe L.; Garceau, Patrick; Tardif, Jean-Claude; Boekholdt, S. Matthijs; Lumbers, R. Thomas; Asselbergs, Folkert W.; Barton, Paul J. R.; Cook, Stuart A.; Prasad, Sanjay K.; O'Regan, Declan P.; van der Velden, Jolanda; Verweij, Karin J. H.; Talajic, Mario; Lettre, Guillaume; Pinto, Yigal M.; Meder, Benjamin; Charron, Philippe; de Boer, Rudolf A.; Christiaans, Imke; Michels, Michelle; Wilde, Arthur A. M.; Watkins, Hugh; Matthews, Paul M.; Ware, James S.; Bezzina, Connie R.

Disease-specific variant pathogenicity prediction significantly improves variant interpretation in inherited cardiac conditions

GENETICS IN MEDICINE

IF6.2

2021-01-01

OAAI

Zhang, Xiaolei; Walsh, Roddy; Whiffin, Nicola; Buchan, Rachel; Midwinter, William; Wilk, Alicja; Govind, Risha; Li, Nicholas; Ahmad, Mian; Mazzarotto, Francesco; Roberts, Angharad; Theotokis, Pantazis I.; Mazaika, Erica; Allouba, Mona; de Marvao, Antonio; Pua, Chee Jian; Day, Sharlene M.; Ashley, Euan; Colan, Steven D.; Michels, Michelle; Pereira, Alexandre C.; Jacoby, Daniel; Ho, Carolyn Y.; Olivotto, Iacopo; Gunnarsson, Gunnar T.; Jefferies, John L.; Semsarian, Chris; Ingles, Jodie; O'Regan, Declan P.; Aguib, Yasmine; Yacoub, Magdi H.; Cook, Stuart A.; Barton, Paul J. R.; Bottolo, Leonardo; Ware, James S.

Genetic Studies of Hypertrophic Cardiomyopathy in Singaporeans Identify Variants in TNNI3 and TNNT2 That Are Common in Chinese Patients 新加坡人肥厚性心肌病的遗传研究确定了中国患者中常见的TNNI3和TNNT2变异

CIRCULATION-GENOMIC AND PRECISION MEDICINE

IF5.5

2020-10-01

OAAI

Pua, Chee Jian; Tham, Nevin; Chin, Calvin W. L.; Walsh, Roddy; Khor, Chiea Chuen; Toepfer, Christopher N.; Repetti, Giuliana G.; Garfinkel, Amanda C.; Ewoldt, Jourdan F.; Cloonan, Paige; Chen, Christopher S.; Lim, Shi Qi; Cai, Jiashen; Loo, Li Yang; Kong, Siew Ching; Chiang, Charleston W. K.; Whiffin, Nicola; de Marvao, Antonio; Lio, Pei Min; Hii, An An; Yang, Cheng Xi; Le, Thu Thao; Bylstra, Yasmin; Lim, Weng Khong; Teo, Jing Xian; Padilha, Kallyandra; Silva, Gabriela V.; Pan, Bangfen; Govind, Risha; Buchan, Rachel J.; Barton, Paul J. R.; Tan, Patrick; Foo, Roger; Yip, James W. L.; Wong, Raymond C. C.; Chan, Wan Xian; Pereira, Alexandre C.; Tang, Hak Chiaw; Jamuar, Saumya Shekhar; Ware, James S.; Seidman, Jonathan G.; Seidman, Christine E.; Cook, Stuart A.

Contemporary Insights Into the Genetics of Hypertrophic Cardiomyopathy: Toward a New Era in Clinical Testing?

JOURNAL OF THE AMERICAN HEART ASSOCIATION

IF5.3

2020-04-21

OAAI

Mazzarotto, Francesco; Olivotto, Iacopo; Boschi, Beatrice; Girolami, Francesca; Poggesi, Corrado; Barton, Paul J. R.; Walsh, Roddy

Reevaluating the Genetic Contribution of Monogenic Dilated Cardiomyopathy

CIRCULATION

IF38.6

2020-02-04

174

OAAI

Mazzarotto, Francesco; Tayal, Upasana; Buchan, Rachel J.; Midwinter, William; Wilk, Alicja; Whiffin, Nicola; Govind, Risha; Mazaika, Erica; de Marvao, Antonio; Dawes, Timothy J. W.; Felkin, Leanne E.; Ahmad, Mian; Theotokis, Pantazis, I; Edwards, Elizabeth; Ing, Alexander Y.; Thomson, Kate L.; Chan, Laura L. H.; Sim, David; Baksi, A. John; Pantazis, Antonis; Roberts, Angharad M.; Watkins, Hugh; Funke, Birgit; O'Regan, Declan P.; Olivotto, Iacopo; Barton, Paul J. R.; Prasad, Sanjay K.; Cook, Stuart A.; Ware, James S.; Walsh, Roddy

Widespread Translational Control of Fibrosis in the Human Heart by RNA-Binding Proteins

CIRCULATION

IF38.6

2019-09-10

OAAI

Chothani, Sonia; Schafer, Sebastian; Adami, Eleonora; Viswanathan, Sivakumar; Widjaja, Anissa A.; Langley, Sarah R.; Tan, Jessie; Wang, Mao; Quaife, Nicholas M.; Pua, Chee Jian; D'Agostino, Giuseppe; Shekeran, Shamini Guna; George, Benjamin L.; Lim, Stella; Cao, Elaine Yiqun; van Heesch, Sebastiaan; Witte, Franziska; Felkin, Leanne E.; Christodoulou, Eleni G.; Dong, Jinrui; Blachut, Susanne; Patone, Giannino; Barton, Paul J. R.; Hubner, Norbert; Cook, Stuart A.; Rackham, Owen J. L.

WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling (vol 10, 3616, 2019)

NATURE COMMUNICATIONS

IF15.7

2019-09-09

OAAI

Chen, Huimei; Moreno-Moral, Aida; Pesce, Francesco; Devapragash, Nithya; Mancini, Massimiliano; Heng, Ee Ling; Rotival, Maxime; Srivastava, Prashant K.; Harmston, Nathan; Shkura, Kirill; Rackham, Owen J. L.; Yu, Wei-Ping; Sun, Xi-Ming; Tee, Nicole Gui Zhen; Tan, Elisabeth Li Sa; Barton, Paul J. R.; Felkin, Leanne E.; Lara-Pezzi, Enrique; Angelini, Gianni; Beltrami, Cristina; Pravenec, Michal; Schafer, Sebastian; Bottolo, Leonardo; Hubner, Norbert; Emanueli, Costanza; Cook, Stuart A.; Petretto, Enrico

WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling WWP2通过调节SMAD2信号调节病理性心脏纤维化

NATURE COMMUNICATIONS

IF15.7

2019-08-09

OAAI

Chen, Huimei; Moreno-Moral, Aida; Pesce, Francesco; Devapragash, Nithya; Mancini, Massimilano; Heng, Ee Ling; Rotival, Maxime; Srivastava, Prashant K.; Harmston, Nathan; Shkura, Kirill; Rackham, Owen J. L.; Yu, Wei-Ping; Sun, Xi-Ming; Tee, Nicole Gui Zhen; Tan, Elisabeth Li Sa; Barton, Paul J. R.; Felkin, Leanne E.; Lara-Pezzi, Enrique; Angelini, Gianni; Beltrami, Cristina; Pravenec, Michal; Schafer, Sebastian; Bottolo, Leonardo; Hubner, Norbert; Emanueli, Costanza; Cook, Stuart A.; Petretto, Enrico

研究方向