未登录 Cediranib with weekly paclitaxel or olaparib versus weekly paclitaxel for advanced or recurrent endometrial cancer (COPELIA): a multicentre, open-label, randomised, phase 2 trial in the UK 西地尼布联合每周多西他赛或奥拉帕利与每周多西他赛对比治疗晚期或复发性子宫内膜癌(COPELIA):一项在英国进行的多中心、开放标签、随机、II期临床试验 Morgan, Robert D.; Porter, Catharine; Zhou, Cong; Kristeleit, Rebecca; Desai, Sudha; Vazquez, Ignacio; George, Angela; Eminowicz, Gemma; Walther, Axel; Franklin, Adrian; Sadozye, Azmat H.; Hughes, Andrew; Hanna, Louise; Roux, Rene; Lord, Rosemary; Bowen, Rebecca; Wood, Joey; Sentamans, Clara; White, Ann; Casbard, Angela C.; Humphrys, Alys; Swettenham, Jennifer B.; Nixon, Lisette S.; Adams, Richard; Ray, Ruby; Brogden, Elena; Powell, Wendy E.; Canham, Joanna; Cox, Tracy M.; Narasimham, Monica; Lowe, Helen; Ensell, Leah; Zubair, Mohammed; Morris, Karen; Glenister-Doyle, Molly; Gassio, Ariadna Fuertes; Morgan, Derrick; Broughton, Dylan; Carucci, Margherita; Monaghan, Phillip J.; Tugwood, Jonathan; Edmondson, Richard J.; Dive, Caroline; Jayson, Gordon C.; Clamp, Andrew R. 分享 收藏
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The Incidence Of Breast Cancer In Ovarian Cancer Patients With BRCA Mutations: A Multicentre Retrospective Cohort Study. BRCA突变卵巢癌患者中乳腺癌的发病率:一项多中心回顾性队列研究。 Yongue, Gabriella; Counsell, Nicholas; Morgan, Robert D.; Tookman, Laura; Devlin, Michael-John; Miller, Rowan; Modawi, Mumin; Leytes, Sophia; Hunt, Ashton; Clamp, Andrew R.; Evans, Gareth R.; Jayson, Gordon C.; Elyashiv, Osnat; Levy, Tally; Abu Remilah, Areen; Ledermann, Jonathan A.; Nicum., Shibani 分享 收藏
Germline BRCA1/2 status and chemotherapy response score in high-grade serous ovarian cancer Morgan, Robert D.; Wang, Xin; Barnes, Bethany M.; Spurgeon, Laura; Carrot, Aurore; Netto, Daniel; Hasan, Jurjees; Mitchell, Claire; Salih, Zena; Desai, Sudha; Shaw, Joseph; Winter-Roach, Brett; Schlecht, Helene; Burghel, George J.; Clamp, Andrew R.; Edmondson, Richard J.; You, Benoit; Evans, D. Gareth R.; Jayson, Gordon C.; Taylor, Stephen S. 分享 收藏
The VALTIVE1 study protocol: a study for the validation of Tie2 as the first tumour vascular response biomarker for VEGF inhibitors Carucci, Margherita; Clamp, Andrew; Zhou, Cong; Hurt, Chris; Glasspool, Rosalind; Monaghan, Phillip J.; Thirkettle, Sally; Wheatley, Michael; Mahmood, Madia; Narasimham, Monica; Cox, Tracy; Morrison, Hilary; Campbell, Susan; Nelson, Annmarie; Holland-Hart, Daniella; Hopewell-Kelly, Noreen; Thomas, Abin; Porter, Catharine; Slusarczyk, Magdalena; Irving, Alys; Dive, Caroline; Adams, Richard; Jayson, Gordon C. 分享 收藏
Extended panel testing in ovarian cancer reveals BRIP1 as the third most important predisposition gene Morgan, Robert D.; Burghel, George J.; Flaum, Nicola; Schlecht, Helene; Clamp, Andrew R.; Hasan, Jurjees; Mitchell, Claire; Salih, Zena; Moon, Sarah; Hogg, Martin; Lord, Rosemary; Forde, Claire; Lalloo, Fiona; Woodward, Emma R.; Crosbie, Emma J.; Taylor, Stephen S.; Jayson, Gordon C.; Evans, D. Gareth R. 分享 收藏
ICON9: International phase III randomized study to evaluate the efficacy of maintenance therapy with olaparib and cediranib or olaparib alone in patients with relapsed platinum-sensitive ovarian cancer following a response to platinum-based chemotherapy ICON9: 国际III期随机研究,旨在评估奥拉帕利联合西地尼布或奥拉帕利单药维持治疗在铂类化疗有效后复发的铂敏感卵巢癌患者中的疗效。 Nicum, S.; Ledermann, J. A.; Mileshkin, L.; Jayson, G. C.; Gourley, C.; Michael, A.; Lord, R.; Mackay, H.; Hall, M.; Tookman, L.; Banerjee, S.; Harnett, P.; Macdonald, I.; Lee, Y. C.; Elyashiv, O.; Wilkinson, K.; Farrelly, L.; Counsell, N. 分享 收藏
Association between chemotherapy response score (CRS) and tumour homologous recombination deficiency (tHRD) in women with newly diagnosed FIGO stage IIIC/IV high-grade serous ovarian cancer (HGSOC) 新诊断为FIGO分期IIIC/IV期的高级别浆液性卵巢癌(HGSOC)女性患者中,化疗反应评分(CRS)与肿瘤同源重组缺陷(tHRD)之间的关联。 Britton, F.; Zhou, C.; Burghel, G. J.; Schlecht, H.; Desai, S.; Barnes, B.; Clamp, A. R.; Hasan, J.; Mitchell, C. L.; Salih, Z.; Edmondson, R.; Evans, G. D.; Jayson, G. C.; Taylor, S.; Morgan, R. D. 分享 收藏
Testing unselected women with newly diagnosed high-grade serous ovarian cancer (HGSOC) for germline pathogenic variants (PVs) in mismatch repair (MMR) genes is unnecessary 对未经筛选的、新诊断为高级别浆液性卵巢癌(HGSOC)的女性进行错配修复(MMR)基因的胚系致病变异(PVs)检测是不必要的。 Spurgeon, L.; Burghel, G. J.; Schlecht, H.; Clamp, A. R.; Hasan, J.; Mitchell, C. L.; Salih, Z.; Woodward, E. R.; Crosbie, E.; Taylor, S.; Jayson, G. C.; Evans, G. D.; Morgan, R. D. 分享 收藏
Results of a randomised Phase II trial of olaparib, chemotherapy or olaparib and cediranib in patients with platinum-resistant ovarian cancer Nicum, Shibani; Mcgregor, Naomi; Austin, Rachel; Collins, Linda; Dutton, Susan; Mcneish, Iain; Glasspool, Rosalind; Hall, Marcia; Roux, Rene; Michael, Agnieszka; Clamp, Andrew; Jayson, Gordon; Kristeleit, Rebecca; Banerjee, Susana; Mansouri, Anita 分享 收藏
Correlation between chemotherapy response score (CRS) and germline BRCA1/2 (gBRCA) status in women diagnosed with FIGO stage IIIC/IV high-grade serous ovarian cancer (HGSOC) Netto, D.; Wang, X.; Barnes, B.; Clamp, A. R.; Hasan, J.; Mitchell, C. L.; Salih, Z.; Winter-Roach, B.; Edmondson, R.; Shaw, J.; Desai, S.; Schlecht, H.; Burghel, G. J.; Taylor, S.; Evans, G.; Jayson, G. C.; Morgan, R. D. 分享 收藏
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Homologous recombination deficiency in newly diagnosed FIGO stage III/IV high-grade serous or endometrioid ovarian cancer: A multi-national observational study Morgan, R. D.; Clamp, A. R.; Barnes, B.; Schlecht, H.; Yarram-Smith, L.; Wallis, Y.; Morgan, S.; Valganon, M.; Hudson, E.; McKenna, S.; Sundar, S.; Nicum, S.; Brenton, J. D.; Kristeleit, R.; Banerjee, S.; McNeish, I.; Ledermann, J. A.; Taylor, S.; Evans, G.; Jayson, G. C. 分享 收藏
Home Parenteral Nutrition in Patients with Advanced Cancer: Quality Outcomes from a Centralized Model of Care Delivery Kopczynska, Maja; Teubner, Antje; Abraham, Arun; Taylor, Michael; Bond, Ashley; Clamp, Andrew; Wight, Rebecca; Salih, Zena; Hasan, Jurjees; Mitchell, Claire; Jayson, Gordon C.; Lal, Simon 分享 收藏
A first-in-human Phase I dose-escalation trial of the novel therapeutic peptide, ALM201, demonstrates a favourable safety profile in unselected patients with ovarian cancer and other advanced solid tumours El Helali, Aya; Plummer, Ruth; Jayson, Gordon C.; Coyle, Vicky M.; Drew, Yvette; Mescallado, Nerissa; Harris, Noor; Clamp, Andrew R.; McCann, Janine; Swaisland, Helen; Kennedy, Richard D.; Cranston, Aaron N.; Wilson, Richard H. 分享 收藏
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BRCA1/2 in non-mucinous epithelial ovarian cancer: tumour with or without germline testing? Morgan, Robert D.; Burghel, George J.; Flaum, Nicola; Bulman, Michael; Smith, Philip; Clamp, Andrew R.; Hasan, Jurjees; Mitchell, Claire L.; Salih, Zena; Woodward, Emma R.; Lalloo, Fiona; Crosbie, Emma J.; Edmondson, Richard J.; Wallace, Andrew J.; Jayson, Gordon C.; Evans, D. Gareth R. 分享 收藏
c-MET/VEGFR-2 co-localisation impacts on survival following bevacizumab therapy in epithelial ovarian cancer: an exploratory biomarker study of the phase 3 ICON7 trial Morgan, Robert D.; Ferreras, Cristina; Peset, Isabel; Avizienyte, Egle; Renehan, Andrew G.; Edmondson, Richard J.; Murphy, Alexander D.; Nicum, Shibani; Van Brussel, Thomas; Clamp, Andrew R.; Lambrechts, Diether; Zhou, Cong; Jayson, Gordon C. 分享 收藏
Safety and efficacy of the tumor-selective adenovirus enadenotucirev with or without paclitaxel in platinum-resistant ovarian cancer: a phase 1 clinical trial Moreno, Victor; Barretina-Ginesta, Maria-Pilar; Garcia-Donas, Jesus; Jayson, Gordon C.; Roxburgh, Patricia; Vazquez, Raul Marquez; Michael, Agnieszka; Anton-Torres, Antonio; Brown, Richard; Krige, David; Champion, Brian; McNeish, Iain 分享 收藏
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