Eileen E. M. Furlong - Publications, H-index & Citations

Eileen E. M. Furlong

genome biology unit

56H指数

148论文数

1.5W被引数

收录论文 66

发表时间

Chromatin context shapes SPT5 regulation of promoter-proximal Pol II, fine-tuning gene expression changes during Drosophila embryogenesis 染色质环境塑造SPT5对启动子邻近Pol II的调控，精调果蝇胚胎发育过程中的基因表达变化

Developmental Cell

IF8.7

2026-09-04

OAAI

Alessandro Dulja; Marvin Mayer; Niklas Engel; Arkadiy K. Golov; Katharina Bender; Mattia Forneris; Yacine Kherdjemil; Songjie Feng; Rebecca R. Viales; Eileen E.M. Furlong

Enhancer-promoter interactions become more instructive in the transition from cell-fate specification to tissue differentiation

NATURE GENETICS

IF31.8

2024-03-11

OAAI

Pollex, Tim; Rabinowitz, Adam; Gambetta, Maria Cristina; Marco-Ferreres, Raquel; Viales, Rebecca R.; Jankowski, Aleksander; Schaub, Christoph; Furlong, Eileen E. M.

Chromatin gene-gene loops support the cross-regulation of genes with related function

MOLECULAR CELL

IF16.6

2024-03-01

OAAI

Pollex, Tim; Marco-Ferreres, Raquel; Ciglar, Lucia; Ghavi-Helm, Yad; Rabinowitz, Adam; Viales, Rebecca Rodriguez; Schaub, Christoph; Jankowski, Aleksander; Girardot, Charles; Furlong, Eileen E. M.

In Vivo Silencing of Regulatory Elements Using a Single AAV-CRISPRi Vector 使用单个aav-crispri载体在体内沉默调控元件

CIRCULATION RESEARCH

IF16.2

2024-01-19

OAAI

Laurette, P.; Cao, C.; Ramanujam, D.; Schwaderer, M.; Lueneburg, T.; Kuss, S.; Weiss, L.; Dilshat, R.; Furlong, E. E. M.; Rezende, F.; Engelhardt, S.; Gilsbach, R.

CTCF, BEAF-32, and CP190 are not required for the establishment of TADs in early Drosophila embryos but have locus-specific roles

SCIENCE ADVANCES

IF12.5

2023-02-03

OAAI

Cavalheiro, Gabriel R.; Girardot, Charles; Viales, Rebecca R.; Pollex, Tim; Cao, T. B. Ngoc; Lacour, Perrine; Feng, Songjie; Rabinowitz, Adam; Furlong, Eileen E. M.

Enhancers have more cofactor specificity than we think: A potential new way to classify enhancers based on their functional cofactor requirements

MOLECULAR CELL

IF16.6

2022-08-01

OAAI

Pijuan-Sala, Blanca; Furlong, Eileen E. M.

Regulating specificity in enhancer-promoter communication

CURRENT OPINION IN CELL BIOLOGY

IF4.3

2022-04-01

PREAI

Galouzis, Charalampos Chrysovalantis; Furlong, Eileen E. M.

Simultaneous cellular and molecular phenotyping of embryonic mutants using single-cell regulatory trajectories

DEVELOPMENTAL CELL

IF8.7

2022-02-01

OAAI

Secchia, Stefano; Forneris, Mattia; Heinen, Tobias; Stegle, Oliver; Furlong, Eileen E. M.

scDALI: modeling allelic heterogeneity in single cells reveals context-specific genetic regulation

GENOME BIOLOGY

IF9.4

2022-01-06

OAAI

Heinen, Tobias; Secchia, Stefano; Reddington, James P.; Zhao, Bingqing; Furlong, Eileen E. M.; Stegle, Oliver

Extremely rapid and reversible optogenetic perturbation of nuclear proteins in living embryos

DEVELOPMENTAL CELL

IF8.7

2021-08-01

OAAI

Koegler, Anna C.; Kherdjemil, Yacine; Bender, Katharina; Rabinowitz, Adam; Marco-Ferreres, Raquel; Furlong, Eileen E. M.

The hourglass model of evolutionary conservation during embryogenesis extends to developmental enhancers with signatures of positive selection

GENOME RESEARCH

IF5.5

2021-07-15

OAAI

Liu, Jialin; Viales, Rebecca R.; Khoueiry, Pierre; Reddington, James P.; Girardot, Charles; Furlong, Eileen E. M.; Robinson-Rechavi, Marc

To loop or not to loop: what is the role of TADs in enhancer function and gene regulation?

CURRENT OPINION IN GENETICS & DEVELOPMENT

IF3.6

2021-04-01

PREAI

Cavalheiro, Gabriel R.; Pollex, Tim; Furlong, Eileen E. M.

Cis-acting variation is common across regulatory layers but is often buffered during embryonic development

GENOME RESEARCH

IF5.5

2020-12-11

OAAI

Floc'hlay, Swann; Wong, Emily S.; Zhao, Bingqing; Viales, Rebecca R.; Thomas-Chollier, Morgane; Thieffry, Denis; Garfield, David A.; Furlong, Eileen E. M.

Lineage-Resolved Enhancer and Promoter Usage during a Time Course of Embryogenesis

DEVELOPMENTAL CELL

IF8.7

2020-12-01

OAAI

Reddington, James P.; Garfield, David A.; Sigalova, Olga M.; Calviello, Aslihan Karabacak; Marco-Ferreres, Raquel; Girardot, Charles; Viales, Rebecca R.; Degner, Jacob F.; Ohler, Uwe; Furlong, Eileen E. M.

The road ahead in genetics and genomics 遗传学和基因组学的未来之路

NATURE REVIEWS GENETICS

IF52

2020-08-24

128

OAAI

McGuire, Amy L.; Gabriel, Stacey; Tishkoff, Sarah A.; Wonkam, Ambroise; Chakravarti, Aravinda; Furlong, Eileen E. M.; Treutlein, Barbara; Meissner, Alexander; Chang, Howard Y.; Lopez-Bigas, Nuria; Segal, Eran; Kim, Jin-Soo

Predictive features of gene expression variation reveal mechanistic link with differential expression 基因表达变异的预测特征揭示了与差异表达的机制联系

MOLECULAR SYSTEMS BIOLOGY

IF7.7

2020-08-07

OAAI

Sigalova, Olga M.; Shaeiri, Amirreza; Forneris, Mattia; Furlong, Eileen E. M.; Zaugg, Judith B.

Characterization of Button Loci that Promote Homologous Chromosome Pairing and Cell-Type-Specific Interchromosomal Gene Regulation

DEVELOPMENTAL CELL

IF8.7

2019-11-01

OAAI

Viets, Kayla; Sauria, Michael E. G.; Chernoff, Chaim; Viales, Rebecca Rodriguez; Echterling, Max; Anderson, Caitlin; Tran, Sang; Dove, Abigail; Goyal, Raghav; Voortman, Lukas; Gordus, Andrew; Furlong, Eileen E. M.; Taylor, James; Johnston, Robert J., Jr.

Chromatin topology, condensates and gene regulation: shifting paradigms or just a phase?染色质拓扑，凝聚和基因调控: 转移范式或只是一个阶段？

DEVELOPMENT

IF3.6

2019-10-01

OAAI

Mir, Mustafa; Bickmore, Wendy; Furlong, Eileen E. M.; Narlikar, Geeta

Highly rearranged chromosomes reveal uncoupling between genome topology and gene expression

NATURE GENETICS

IF31.8

2019-07-15

249

OAAI

Ghavi-Helm, Yad; Jankowski, Aleksander; Meiers, Sascha; Viales, Rebecca R.; Korbel, Jan O.; Furlong, Eileen E. M.

BRD4 bimodal binding at promoters and drug-induced displacement at Pol II pause sites associates with I-BET sensitivity

EPIGENETICS & CHROMATIN

IF3.5

2019-07-02

OAAI

Khoueiry, P.; Gahlawat, A. Ward; Petretich, M.; Michon, A. M.; Simola, D.; Lam, E.; Furlong, E. E.; Benes, V; Dawson, M. A.; Prinjha, R. K.; Drewes, G.; Grandi, P.

研究方向