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Pierre Laurent-Puig

Sorbonne Universite
H指数:110
被引数:6.9万

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NUAK1 and AMPK control lipid metabolism, mitochondrial dynamics, and myosin-dependent cell migration in mesenchymal colon cancer cells

NUAK1和AMPK调控间充质结肠癌细胞的脂质代谢、线粒体动力学和肌球蛋白依赖的细胞迁移

Cell Death & Disease
IF9.6
2026-10-300
OA
Clémence Flecchia; Samy Krichi; Victoire Rousseau; Camilla Pilati; Bruno Saubamea; Aurelia Jean-Baptiste; Arnaud Tête; Mourad El Hamri; Virginie Poindessous; Sylvie Bortoli; Catherine Monnot; Delphine Le Corre; Marie Bernelin; Sylvère Durand; Guido Kroemer; Pierre Laurent-Puig; Sophie Mouillet-Richard; Fatima Djouadi
Prognostic and predictive values of transcriptomic signatures in metastatic pancreatic cancer: A biomarker analysis of three French multicenter prospective randomized controlled phase 2 trials (Prodige35, Prodige37 and AFUGEM)

转移性胰腺癌中转录组特征的临床预后和预测价值：对三项法国多中心前瞻性随机对照II期试验（Prodige35、Prodige37和AFUGEM）的生物标志物分析

Cancer Letters
IF10.1
2026-08-010
OAAI
Zhao, Shulin; Nicolle, Remy; Taieb, Julien; Dahan, Laetitia; Abdallah, Raef; Bouche, Olivier; Desrame, Jerome; Phelip, Jean-Marc; Evesque, Ludovic; Akouz, Faiza Khemissa; de Mestier, Louis; Trouilloud, Isabelle; Malka, David; Shen, Baiyong; Cros, Jerome; Laurent-Puig, Pierre; Bachet, Jean-Baptiste
FRUQUITAS trial: Study design of an ENGIC intergroup randomized phase III of trifluridine/tipiracil +/- fruquintinib in pre-treated metastatic gastro-oesophageal adenocarcinoma

FRUQUITAS试验：三氟尿idine/替匹拉西布联合/不联合 fruquintinib治疗经治转移性胃食管腺癌的ENGIC协作组随机III期研究设计

Digestive and Liver Disease
IF3.8
2026-05-090
OAAI
David Tougeron; Fernando Rivera; Tania Fleitas Kanonnikoff; Karine Le Malicot; Meriem Guarssifi; Nadim Fares; Emilie Soularue; Melanie Dos Santos; Mathilde Wagner; Julien Taieb; Thomas Aparicio; Pierre Laurent-Puig; Ulrich T. Hacker; Ana Fernández Montes; Salah-Eddin Al-Batran; Florian Lordick
From clusters to clinic: an 8-gene signature combined with mucinous component stratifies benefit of anti-CTLA-4 addition to anti-PD-1 in dMMR/MSI-H metastatic colorectal cancer

从簇到临床：一个8基因签名与黏液性成分相结合，可分层评估在dMMR/MSI-H转移性结直肠癌中添加抗CTLA-4治疗相对于抗PD-1治疗的获益。

European Journal of Cancer
IF7.1
2026-04-050
OAAI
Margherita Ambrosini; Claire Gallois; Annalice Gandini; Aurélie Lecanu; Emily Alouani; Filippo Pietrantonio; Francesca Bergamo; Chiara Cremolini; Thibault Mazard; David Tougeron; Rosine Guimbaud; Sara Lonardi; Janick Selves; Sophie Mouillet-Richard; Jean-Francois Emile; Julien Taieb; Pierre Laurent-Puig
A predictive model for life-threatening fluoropyrimidine toxicity based on DPYD sequencing in colorectal cancer

基于DPYD测序的结直肠癌患者危及生命氟嘧啶毒性的预测模型

JNCI: Journal of the National Cancer Institute
IF0
2025-12-120
PRE
Valérie Boige, MD; Estelle Menoret, MSc; Gwénaël Le Teuff, PhD; Jean-Christophe Boyer, PhD; Nathalie Cozic, MSc; Jean-Pierre Desvignes, MSc; Julien Taieb, MD; Pierre Laurent-Puig, MD; Yvonne Wettergren, PhD; Matthias Schwab, MD; Stephen Ackland, MBBS; Barbara Jennings, PhD; Anne Sudaka, MD; Eva Seutin, MSc; Christophe Beroud, PhD; Yves Koudou, MSc; Marie-Christine Etienne-Grimaldi, PhD; FUSAFE-2 (Fluoropyrimidine Safe-2) Collaborative Group
A deep learning-based multiscale integration of spatial omics with tumor morphology

基于深度学习的多尺度空间组学与肿瘤形态学集成

Nature Communications
IF15.7
2025-11-270
OAAI
Benoît Schmauch; Loïc Herpin; Antoine Olivier; Thomas Duboudin; Rémy Dubois; Lucie Gillet; Alexandre Filiot; Jean-Baptiste Schiratti; Valentina Di Proietto; Delphine Le Corre; Alexandre Bourgoin; Julien Taïeb; Jean-François Emile; Wolf H. Fridman; Elodie Pronier; Pierre Laurent-Puig; Eric Y. Durand
Characteristics of KRAS WT pancreatic adenocarcinomas: results of a large French multicentric cohort

<i>KRAS</i>野生型胰腺腺癌的特征：一项大型法国多中心队列研究的结果

Therapeutic Advances in Medical Oncology
IF4.2
2025-11-170
OA
Noémie Trystram; Jérome Cros; Hélène Blons; Simon Garinet; Rémy Nicolle; Delphine Le Corre; Shu Lin Zhao; Jim Biagi; Alexandre Harlé; Thierry Conroy; Vinciane Rebours; Julien Taïeb; Laetitia Dahan; Pierre Laurent-Puig; Jean-Baptiste Bachet
A Specific Methylation Class Identifies BAP1-Deficient Meningiomas, Including Meningeal Tumours With Poorly Differentiated Nonrhabdoid Histology

一种特定的甲基化类别可识别BAP1缺陷型脑膜瘤，包括具有未分化非横纹样组织学的脑膜肿瘤。

NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
IF3.4
2025-09-300
OAAI
Drabent, Philippe; Touat, Mehdi; Benusiglio, Patrick R.; Euskirchen, Philipp; Coulet, Florence; Oumoussa, Badreddine Mohand; de la Fouchardiere, Arnaud; de Montpreville, Vincent Thomas; Jacob, Julian; Bernardeschi, Daniele; Laurent-Puig, Pierre; Sanson, Marc; Kalamarides, Michel; Bielle, Franck
Circulating tumor DNA driving anti-EGFR rechallenge therapy in metastatic colorectal cancer: the RASINTRO prospective multicenter study

循环肿瘤DNA驱动抗EGFR再挑战疗法在转移性结直肠癌中的应用：RASINTRO前瞻性多中心研究

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
IF7.2
2025-09-010
PRE
Zaanan, Aziz; Bergen, Elisabeth Sophie; Evesque, Ludovic; Meurisse, Aurelia; Artru, Pascal; Lecomte, Thierry; Bouche, Olivier; Lepere, Celine; Ambrosini, Margherita; Coriat, Romain; Lievre, Astrid; Cohen, Romain; Boige, Valerie; Louafi, Samy; Bachet, Jean-Baptiste; Goyer, Sophie; Taieb, Julien; Vernerey, Dewi; Blons, Helene; Laurent-Puig, Pierre
Deep learning on histological slides accurately predicts Consensus Molecular Subtypes and spatial heterogeneity in colon cancer

基于组织学切片的深度学习能够准确预测结直肠癌的共识分子亚型及空间异质性

Modern Pathology
IF5.5
2025-08-250
PRE
Jean-Eudes LE DOUGET; Paul JACOB; Côme LEPAGE; Claire GALLOIS; Marine SROUSSI; Aurélien D.E. REYNIES; Antoine CAZELLES; Daniel GONZALEZ; Charles MAUSSION; Olivier BOUCHE; Charles-Briac LEVACHE; Marine JARY; Laurent MINEUR; Simon JEGOU; Charlie SAILLARD; Mehdi MOREL; Julien TAÏEB; Frédéric BIBEAU; Jean-François EMILE; Pierre LAURENT-PUIG
FedECA: federated external control arms for causal inference with time-to-event data in distributed settings

FedECA：分布式环境下基于时间-事件数据因果推断的联邦外部控制臂

Nature Communications
IF15.7
2025-08-130
OA
Jean Ogier du Terrail; Quentin Klopfenstein; Honghao Li; Imke Mayer; Nicolas Loiseau; Mohammad Hallal; Michael Debouver; Thibault Camalon; Thibault Fouqueray; Jorge Arellano Castro; Zahia Yanes; Laëtitia Dahan; Julien Taïeb; Pierre Laurent-Puig; Jean-Baptiste Bachet; Shulin Zhao; Remy Nicolle; Jérôme Cros; Daniel Gonzalez; Robert Carreras-Torres; Adelaida Garcia Velasco; Kawther Abdilleh; Sudheer Doss; Félix Balazard; Mathieu Andreux
FOLFIRINOX or FOLFOX for locally advanced or metastatic small bowel adenocarcinoma: PRODIGE 86 – FFCD-GONO – ENGIC 02 – FOLFIRINOX SBA phase II randomized trial

FOLFIRINOX或FOLFOX用于局部晚期或转移性小肠腺癌：PRODIGE 86 – FFCD-GONO – ENGIC 02 – FOLFIRINOX SBA II期随机试验

Digestive and Liver Disease
IF3.8
2025-07-280
OAAI
Thomas Aparicio; Anthony Turpin; Aziz Zaanan; Christelle de la Fouchardière; Karine Le Malicot; Sara Lonardi; Dominik Paul Modest; Richard Wilson; Chiara Cremolini; Alexej Ballhausen; Janet Graham; Annika Kurreck; Meriem Guarssifi; Magali Svrcek; Pierre Laurent-Puig; Sylvain Manfredi
Longitudinal circulating tumor DNA analysis during treatment of locally advanced resectable gastric or gastroesophageal junction adenocarcinoma: the PLAGAST prospective biomarker study

局部晚期可切除胃或胃食管结合部腺癌治疗期间纵向循环肿瘤DNA分析：PLAGAST前瞻性生物标志物研究

Nature Communications
IF15.7
2025-07-240
OAAI
Aziz Zaanan; Audrey Didelot; Chloé Broudin; George Laliotis; Erik Spickard; Punashi Dutta; Aurélien Saltel-Fulero; Francesco Giulio Sullo; Margot Pizzamiglio; Antoine Mariani; Widad Lahlou; Meenakshi Malhotra; Shruti Sharma; Himanshu Sethi; Adham Jurdi; Minetta C. Liu; Pierre Laurent-Puig
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Gastroenterology
IF25.1
2025-06-090
PRE
Camilla Pilati; Julien Taïeb; Pierre Laurent-Puig
Deciphering human endogenous retrovirus expression in colorectal cancers: exploratory analysis regarding prognostic value in liver metastases

解读结直肠癌中内源性逆转录病毒的表达：关于肝转移预后价值的探索性分析

EBIOMEDICINE
IF10.8
2025-06-010
OA
Viot, Julien; Loyon, Romain; Adib, Nawfel; Laurent-Puig, Pierre; de Reynies, Aurelien; Andre, Fabrice; Monnien, Franck; Andre, Thierry; Svrcek, Magali; Selmani, Zohair; Arnould, Laurent; Guyard, Laura; Gilbert, Nicolas; Boureux, Anthony; Adotevi, Olivier; Vienot, Angelique; Abdeljaoued, Syrine; Vernerey, Dewi; Borg, Christophe; Gautheret, Daniel

研究方向

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H
Hélène Blons
H 指数:56论文数:340被引数:1.0万
J
Julien Taı̈eb
H 指数:98论文数:1,374被引数:4.3万
A
Aziz Zaanan
H 指数:41论文数:268被引数:1.0万
V
Valérie Taly
H 指数:54论文数:234被引数:1.1万
C
Claire Mulot
H 指数:32论文数:193被引数:8,392
D
Delphine Le Corre
H 指数:23论文数:142被引数:6,475
J
Jessica Zucman‐Rossi
H 指数:106论文数:710被引数:6.5万
A
Audrey Didelot
H 指数:20论文数:84被引数:2,092
J
Jean‐François Emile
H 指数:87论文数:570被引数:3.3万
A
Aurélien de Reyniès
H 指数:71论文数:427被引数:3.4万