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J

Joseph M. Chan

Memorial Sloan Kettering Cancer Center
H指数:28
被引数:7,352

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ZFP36L2 orchestrates stress-adaptive plasticity in regeneration and cancer

ZFP36L2在再生与癌症中调控应激适应性可塑性

Nature
IF48.5
2026-08-050
OA
Qingwen Jiang; Manisha S. Raghavan; Aileen M. Rodriguez; Morgan Lallo; Cyrus L. Tam; Saskia Hartner; Britney Forsyth; Ahmed Mahmoud; Fabian Zincke; Huiyong Zhao; Andrew Moorman; Sasha Balkaran; Kathleen Luckett; Jura Pintar; Yevgeniy Romin; Eric Chan; Anthony Santella; Bernadette Mödl; Farheen Shah; Ilyes Baali; Michael G. Kharas; Elisa de Stanchina; Nil Urganci; Jinru Shia; Dana Pe’er; Francisco Sanchez-Vega; Richard Koche; Quaid Morris; Joseph M. Chan; Karuna Ganesh
Actin dysregulation induces neuroendocrine plasticity and immune evasion: a vulnerability of small cell lung cancer

肌动蛋白失调诱导神经内分泌可塑性和免疫逃逸：小细胞肺癌的易损性

Nature Communications
IF15.7
2025-12-060
OAAI
Yoojeong Seo; Shengzhe Zhang; Jinho Jang; Kyung-Pil Ko; Kee-Beom Kim; Yuanjian Huang; Dong-Wook Kim; Bongjun Kim; Gengyi Zou; Jie Zhang; Sohee Jun; Wonhong Chu; Nicole A. Kirk; Ye Eun Hwang; Young Ho Ban; Shilpa S. Dhar; Joseph M. Chan; Min Gyu Lee; Charles M. Rudin; Kwon-Sik Park; Jae-Il Park
Basal cell of origin resolves neuroendocrine–tuft lineage plasticity in cancer

起源的基底细胞解决了癌症中神经内分泌-簇细胞谱系的可塑性

Nature
IF48.5
2025-09-170
OA
Abbie S. Ireland; Daniel A. Xie; Sarah B. Hawgood; Margaret W. Barbier; Lisa Y. Zuo; Benjamin E. Hanna; Scarlett Lucas-Randolph; Darren R. Tyson; Benjamin L. Witt; Ramaswamy Govindan; Afshin Dowlati; Justin C. Moser; Anish Thomas; Sonam Puri; Charles M. Rudin; Joseph M. Chan; Andrew Elliott; Trudy G. Oliver
Functional characterization of the ATOH1 molecular subtype indicates a pro-metastatic role in small cell lung cancer

ATOH1分子亚型的功能表征表明其在小细胞肺癌中具有促转移作用。

CELL REPORTS
IF6.9
2025-05-010
PRE
Catozzi, Alessia; Pages, Maria Peiris; Humphrey, Sam; Revill, Mitchell; Morgan, Derrick; Roebuck, Jordan; Chen, Yitao; Davies-Williams, Bethan; Brennan, Kevin; Hossain, A. S. Md. Mukarram; Makeev, Vsevolod J.; Satia, Karishma; Sfyri, Pagona P.; Galvin, Melanie; Coles, Darryl; Lallo, Alice; Pearce, Simon P.; Kerr, Alastair; Priest, Lynsey; Foy, Victoria; Carter, Mathew; Caeser, Rebecca; Chan, Joseph M.; Rudin, Charles M.; Blackhall, Fiona; Frese, Kristopher K.; Dive, Caroline; Simpson, Kathryn L.
ATR inhibition activates cancer cell cGAS/STING-interferon signaling and promotes antitumor immunity in small-cell lung cancer
SCIENCE ADVANCES
IF12.5
2024-09-271
OAAI
Taniguchi, Hirokazu; Chakraborty, Subhamoy; Takahashi, Nobuyuki; Banerjee, Avisek; Caeser, Rebecca; Zhan, Yingqian A.; Tischfield, Sam E.; Chow, Andrew; Nguyen, Evelyn M.; Villalonga, Alvaro Quintanal; Manoj, Parvathy; Shah, Nisargbhai S.; Rosario, Samantha; Hayatt, Omar; Qu, Rui; de Stanchina, Elisa; Chan, Joseph; Mukae, Hiroshi; Thomas, Anish; Rudin, Charles M.; Sen, Triparna
Single- cell analysis of treatment- resistant prostate cancer: Implications of cell state changes for cell surface antigen- targeted therapies
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2024-07-054
OAAI
Zaidi, Samir; Park, Jooyoung; Chan, Joseph M.; Roudier, Martine P.; Zhao, Jimmy L.; Gopalan, Anuradha; Wadosky, Kristine M.; Patel, Radhika A.; Sayar, Erolcan; Karthaus, Wouter R.; Kates, D. Henry; Chaudhary, Ojasvi; Xu, Tianhao; Masilionis, Ignas; Mazutis, Linas; Chaligne, Ronan; Obradovic, Aleksandar; Linkov, Irina; Barlas, Afsar; Jungbluth, Achim A.; Rekhtman, Natasha; Silber, Joachim; Manova-Todorova, Katia; Watson, Philip A.; True, Lawrence D.; Morrissey, Colm; Scher, Howard I.; Rathkopf, Dana E.; Morris, Michael J.; Goodrich, David W.; Choi, Jungmin; Nelson, Peter S.; Haffner, Michael C.; Sawyers, Charles L.
The ectonucleotidase CD39 identifies tumor-reactive CD8+T cells predictive of immune checkpoint blockade efficacy in human lung cancer

外核酸酶CD39识别肿瘤反应性CD8 T细胞，预测人类肺癌中免疫检查点阻断功效

IMMUNITY
IF26.3
2023-01-0146
PRE
Chow, Andrew; Uddin, Fathema Z.; Liu, Michael; Dobrin, Anton; Nabet, Barzin Y.; Mangarin, Levi; Lavin, Yonit; Rizvi, Hira; Tischfield, Sam E.; Quintanal-Villalonga, Alvaro; Chan, Joseph M.; Shah, Nisargbhai; Allaj, Viola; Manoj, Parvathy; Mattar, Marissa; Meneses, Maximiliano; Landau, Rebecca; Ward, Mariana; Kulick, Amanda; Kwong, Charlene; Wierzbicki, Matthew; Yavner, Jessica; Egger, Jacklynn; Chavan, Shweta S.; Farillas, Abigail; Holland, Aliya; Sridhar, Harsha; Ciampricotti, Metamia; Hirschhorn, Daniel; Guan, Xiangnan; Richards, Allison L.; Heller, Glenn; Mansilla-Soto, Jorge; Sadelain, Michel; Klebanoff, Christopher A.; Hellmann, Matthew D.; Sen, Triparna; de Stanchina, Elisa; Wolchok, Jedd D.; Merghoub, Taha; Rudin, Charles M.
WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC
CELL REPORTS
IF6.9
2022-05-0162
OAAI
Taniguchi, Hirokazu; Caeser, Rebecca; Chavan, Shweta S.; Zhan, Yingqian A.; Chow, Andrew; Manoj, Parvathy; Uddin, Fathema; Kitai, Hidenori; Qu, Rui; Hayatt, Omar; Shah, Nisargbhai S.; Villalonga, Alvaro Quintanal; Allaj, Viola; Nguyen, Evelyn M.; Chan, Joseph; Michel, Adam O.; Mukae, Hiroshi; de Stanchina, Elisa; Rudin, Charles M.; Sen, Triparna
Inhibition of XPO1 Sensitizes Small Cell Lung Cancer to First- and Second-Line Chemotherapy
CANCER RESEARCH
IF16.6
2022-02-0228
OA
Quintanal-Villalonga, Alvaro; Taniguchi, Hirokazu; Hao, Yuan; Chow, Andrew; Zhan, Yingqian A.; Chavan, Shweta S.; Uddin, Fathema; Allaj, Viola; Manoj, Parvathy; Shah, Nisargbhai S.; Chan, Joseph M.; Offin, Michael; Ciampricotti, Metamia; Ray-Kirton, Jordana; Egger, Jacklynn; Bhanot, Umesh; Linkov, Irina; Asher, Marina; Roehrl, Michael H.; Qiu, Juan; de Stanchina, Elisa; Hollmann, Travis J.; Koche, Richard P.; Sen, Triparna; Poirier, John T.; Rudin, Charles M.
Lineage plasticity in prostate cancer depends on JAK/STAT inflammatory signaling

前列腺癌的谱系可塑性取决于JAK/STAT炎症信号

Science
IF45.8
2022-01-010
OA
Joseph Minhow Chan; Samir Zaidi; Jillian R Love; Jimmy L. Zhao; Manu N. Setty; Kristine M. Wadosky; Anuradha Gopalan; Zi-Ning Choo; Sitara Persad; Jungmin Choi; Justin R. LaClair; Kayla E. Lawrence; Ojasvi Chaudhary; Tianhao Xu; Ignas Masilionis; Irina Linkov; Shangqian Wang; Cindy Lee; Afşar Barlas; Michael J. Morris; Linas Mažutis; Ronan Chaligné; Yu Chen; David W. Goodrich; Wouter R. Karthaus; Dana Pe’er; Charles L. Sawyers
Comprehensive molecular characterization of lung tumors implicates AKT and MYC signaling in adenocarcinoma to squamous cell transdifferentiation
JOURNAL OF HEMATOLOGY & ONCOLOGY
IF40.4
2021-10-1642
OAAI
Quintanal-Villalonga, Alvaro; Taniguchi, Hirokazu; Zhan, Yingqian A.; Hasan, Maysun M.; Chavan, Shweta S.; Meng, Fanli; Uddin, Fathema; Allaj, Viola; Manoj, Parvathy; Shah, Nisargbhai S.; Chan, Joseph M.; Ciampricotti, Metamia; Chow, Andrew; Offin, Michael; Ray-Kirton, Jordana; Egger, Jacklynn D.; Bhanot, Umesh K.; Linkov, Irina; Asher, Marina; Roehrl, Michael H.; Ventura, Katia; Qiu, Juan; de Stanchina, Elisa; Chang, Jason C.; Rekhtman, Natasha; Houck-Loomis, Brian; Koche, Richard P.; Yu, Helena A.; Sen, Triparna; Rudin, Charles M.
Tumor Analyses Reveal Squamous Transformation and Off-Target Alterations As Early Resistance Mechanisms to First-line Osimertinib in EGFR-Mutant Lung Cancer
CLINICAL CANCER RESEARCH
IF10.2
2020-06-01268
PRE
Schoenfeld, Adam J.; Chan, Joseph M.; Kubota, Daisuke; Sato, Hiroki; Rizvi, Hira; Daneshbod, Yahya; Chang, Jason C.; Paik, Paul K.; Offin, Michael; Arcila, Maria E.; Davare, Monika A.; Shinde, Ujwal; Pe'er, Dana; Rekhtman, Natasha; Kris, Mark G.; Somwar, Romel; Riely, Gregory J.; Ladanyi, Marc; Yu, Helena A.

研究方向

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C
Charles M. Rudin
H 指数:132论文数:1,694被引数:8.6万
T
Triparna Sen
H 指数:38论文数:317被引数:7,411
À
Àlvaro Quintanal-Villalonga
H 指数:25论文数:149被引数:3,753
A
Andrew Chow
H 指数:52论文数:224被引数:1.7万
D
Dana Pe’er
H 指数:86论文数:371被引数:5.2万
E
Elisa de Stanchina
H 指数:94论文数:1,296被引数:3.9万
P
Parvathy Manoj
H 指数:15论文数:113被引数:1,057
R
Raúl Rabadán
H 指数:83论文数:713被引数:3.5万
N
Nisargbhai Shah
H 指数:17论文数:92被引数:1,819
H
Helena A. Yu
H 指数:58论文数:643被引数:1.6万