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M

Myles Brown

harvard medical school
H指数:127
被引数:8.4万

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Epigenetic subtypes of high-grade T1 bladder cancer reveal intra-tumor heterogeneity and distinct interactions with tumor microenvironment

高级别T1膀胱癌的表观遗传亚型揭示肿瘤内异质性和与肿瘤微环境的独特相互作用

Theranostics
IF13.3
2026-05-180
PRE
Bellmunt, Joaquim; Xie, Yingtian; Juanpere, Nuria; Munoz, Miguel Gomez; Kukreja, Shweta; Veiga, Sonsoles Liria; Li, Rong; Qiu, Xintao; Jiang, Yijia; Font-Tello, Alba; Duarte, Marie Nunez; Epstein, Ilana; Hernandez-Llodra, Silvia; Lorenzo, Marta; Menendez, Silvia; Choueiri, Toni; Brown, Myles; Long, Henry W.; Cejas, Paloma
Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function

EZH2的AMPK磷酸化抑制PRC2甲基转移酶活性和致癌功能

Molecular Cell
IF16.6
2025-08-130
PRE
Lixin Wan; Kexin Xu; Yongkun Wei; Jinfang Zhang; Tao Han; Christopher Fry; Zhao Zhang; Yao Vickie Wang; Liyu Huang; Min Yuan; Weiya Xia; Wei-Chao Chang; Wen-Chien Huang; Chien-Liang Liu; Yuan-Ching Chang; Jinsong Liu; Yun Wu; Victor X. Jin; Xiangpeng Dai; Jianfeng Guo; Jia Liu; Shulong Jiang; Jin Li; John M. Asara; Myles Brown; Mien-Chie Hung; Wenyi Wei
Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function

EZH2的磷酸化由AMPK介导，抑制了PRC2甲基转移酶活性和致癌功能。

Molecular Cell
IF16.6
2025-07-230
PRE
Lixin Wan; Kexin Xu; Yongkun Wei; Jinfang Zhang; Tao Han; Christopher Fry; Zhao Zhang; Yao Vickie Wang; Liyu Huang; Min Yuan; Weiya Xia; Wei-Chao Chang; Wen-Chien Huang; Chien-Liang Liu; Yuan-Ching Chang; Jinsong Liu; Yun Wu; Victor X. Jin; Xiangpeng Dai; Jianfeng Guo; Jia Liu; Shulong Jiang; Jin Li; John M. Asara; Myles Brown; Mien-Chie Hung; Wenyi Wei
Increased nuclear factor I-mediated chromatin access drives transition to androgen receptor splice variant dependence in prostate cancer

核因子I介导的染色质可及性增加驱动前列腺癌向雄激素受体剪接变异体依赖性转变

CELL REPORTS
IF6.9
2025-01-011
OA
Poluben, Larysa; Nouri, Mannan; Liang, Jiaqian; Chen, Shaoyong; Varkaris, Andreas; Ersoy-Fazlioglu, Betul; Voznesensky, Olga; Lee, Irene I.; Qiu, Xintao; Cato, Laura; Seo, Ji-Heui; Freedman, Matthew L.; Sowalsky, Adam G.; Lack, Nathan A.; Corey, Eva; Nelson, Peter S.; Brown, Myles; Long, Henry W.; Russo, Joshua W.; Balk, Steven P.
ZBTB7A is a modulator of KDM5-driven transcriptional networks in basal breast cancer
CELL REPORTS
IF6.9
2024-12-010
PRE
Diciaccio, Benedetto; Seehawer, Marco; Li, Zheqi; Patmanidis, Andriana; Bui, Triet; Foidart, Pierre; Nishida, Jun; D'Santos, Clive S.; Papachristou, Evangelia K.; Papanastasiou, Malvina; Reiter, Andrew H.; Qiu, Xintao; Li, Rong; Jiang, Yijia; Huang, Xiao-Yun; Simeonov, Anton; Kales, Stephen C.; Rai, Ganesha; Lal-Nag, Madhu; Jadhav, Ajit; Brown, Myles; Carroll, Jason S.; Long, Henry W.; Polyak, Kornelia
Lineage-specific canonical and non-canonical activity of EZH2 in advanced prostate cancer subtypes
NATURE COMMUNICATIONS
IF15.7
2024-08-082
OAAI
Venkadakrishnan, Varadha Balaji; Presser, Adam G.; Singh, Richa; Booker, Matthew A.; Traphagen, Nicole A.; Weng, Kenny; Voss, Nathaniel C. E.; Mahadevan, Navin R.; Mizuno, Kei; Puca, Loredana; Idahor, Osasenaga; Ku, Sheng-Yu; Bakht, Martin K.; Borah, Ashir A.; Herbert, Zachary T.; Tolstorukov, Michael Y.; Barbie, David A.; Rickman, David S.; Brown, Myles; Beltran, Himisha
Thio-2 Inhibits Key Signaling Pathways Required for the Development and Progression of Castration-resistant Prostate Cancer
MOLECULAR CANCER THERAPEUTICS
IF5.5
2024-02-272
OAAI
Neeb, Antje; Figueiredo, Ines; Bogdan, Denisa; Cato, Laura; Stober, Jutta; Jimenez-Vacas, Juan M.; Gourain, Victor; Lee, Irene I.; Seeger, Rebecca; Muhle-Goll, Claudia; Gurel, Bora; Welti, Jonathan; Nava Rodrigues, Daniel; Rekowski, Jan; Qiu, Xintao; Jiang, Yija; Di Micco, Patrizio; Mateos, Borja; Bielskute, Stase; Riisnaes, Ruth; Ferreira, Ana; Miranda, Susana; Crespo, Mateus; Buroni, Lorenzo; Ning, Jian; Carreira, Suzanne; Braese, Stefan; Jung, Nicole; Graessle, Simone; Swain, Amanda; Salvatella, Xavier; Plymate, Stephen R.; Al-Lazikani, Bissan; Long, Henry W.; Yuan, Wei; Brown, Myles; Cato, Andrew C. B.; de Bono, Johann S.; Sharp, Adam
Heterogeneity and transcriptional drivers of triple-negative breast cancer
CELL REPORTS
IF6.9
2023-12-015
OAAI
Jovanovic, Bojana; Temko, Daniel; Stevens, Laura E.; Seehawer, Marco; Fassl, Anne; Murphy, Katherine; Anand, Jayati; Garza, Kodie; Gulvady, Anushree; Qiu, Xintao; Harper, Nicholas W.; Daniels, Veerle W.; Huang, Xiao-Yun; Ge, Jennifer Y.; Aleckovic, Masa; Pyrdol, Jason; Hinohara, Kunihiko; Egri, Shawn B.; Papanastasiou, Malvina; Vadhi, Raga; Font-Tello, Alba; Witwicki, Robert; Peluffo, Guillermo; Trinh, Anne; Shu, Shaokun; Diciaccio, Benedetto; Ekram, Muhammad B.; Subedee, Ashim; Herbert, Zachary T.; Wucherpfennig, Kai W.; Letai, Anthony G.; Jaffe, Jacob D.; Sicinski, Piotr; Brown, Myles; Dillon, Deborah; Long, Henry W.; Michor, Franziska; Polyak, Kornelia
TP63 fusions drive multicomplex enhancer rewiring, lymphomagenesis, and EZH2 dependence
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2023-09-205
OA
Wu, Gongwei; Yoshida, Noriaki; Liu, Jihe; Zhang, Xiaoyang; Xiong, Yuan; Heavican-Foral, Tayla B.; Mandato, Elisa; Liu, Huiyun; Nelson, Geoffrey M.; Yang, Lu; Chen, Renee; Donovan, Katherine A.; Jones, Marcus K.; Roshal, Mikhail; Zhang, Yanming; Xu, Ran; Nirmal, Ajit J.; Jain, Salvia; Leahy, Catharine; Jones, Kristen L.; Stevenson, Kristen E.; Galasso, Natasha; Ganesan, Nivetha; Chang, Tiffany; Wu, Wen-Chao; Louissaint, Abner; Debaize, Lydie; Yoon, Hojong; Dal Cin, Paola; Chan, Wing C.; Ho Sui, Shannan J.; Ng, Samuel Y.; Feldman, Andrew L.; Horwitz, Steven M.; Adelman, Karen; Fischer, Eric S.; Chen, Chun-Wei; Weinstock, David M.; Brown, Myles

研究方向

暂未获取到该数据
X
X. Shirley Liu
H 指数:88论文数:484被引数:8.1万
H
Henry W. Long
H 指数:56论文数:622被引数:1.2万
C
Clifford A. Meyer
H 指数:57论文数:270被引数:3.9万
R
Rinath Jeselsohn
H 指数:39论文数:566被引数:6,175
P
Philip W. Kantoff
H 指数:137论文数:1,364被引数:9.0万
X
Xintao Qiu
H 指数:31论文数:389被引数:4,840
P
Paloma Cejas
H 指数:40论文数:310被引数:9,237
T
Tengfei Xiao
H 指数:39论文数:103被引数:8,826
J
Jason S. Carroll
H 指数:88论文数:644被引数:3.4万
M
Massimo Loda
H 指数:133论文数:1,585被引数:8.0万