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A phase II trial of mTORC1/2 inhibition in STK11 deficient non small cell lung cancer STK11缺失的非小细胞肺癌中mTORC1/2抑制的II期试验 Middleton, Gary; Robbins, Helen L.; Fletcher, Peter; Mehmi, Manita; Summers, Yvonne; Greystoke, Alastair; Steele, Nicola; Popat, Sanjay; Jain, Pooja; Spicer, James; Cave, Judith; Shaw, Paul; Gilligan, David; Power, Danielle; Fennell, Dean; Bajracharya, Maya; Mcbride, David J.; Maheswari, Uma; Frankell, Alexander M.; Swanton, Charles; Beggs, Andrew D.; Billingham, Lucinda 分享 收藏
The potential clinical utility of Whole Genome Sequencing for patients with cancer: evaluation of a regional implementation of the 100,000 Genomes Project 癌症患者全基因组测序的潜在临床应用: 100,000基因组计划的区域实施评估 Leung, Elaine Y. L.; Robbins, Helen L.; Zaman, Shafquat; Lal, Neeraj; Morton, Dion; Dew, Lisa; Williams, Anthony P.; Wallis, Yvonne; Bell, Jennie; Raghavan, Manoj; Middleton, Gary; Beggs, Andrew D. 分享 收藏
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Real-world utility of whole genome sequencing for patients with cancer: Evaluation of a regional implementation of the 100,000 genomes project 癌症患者全基因组测序的现实应用：对“100,000 Genomes Project”区域性实施的评价 Robbins, H. L.; Leung, E.; Zaman, S.; Lal, N.; Morton, D.; Dew, L.; Williams, A.; Wallis, Y.; Bell, J.; Raghavan, M.; Middleton, G.; Beggs, A. D. 分享 收藏
Extended pleurectomy decortication and chemotherapy versus chemotherapy alone for pleural mesothelioma (MARS 2): a phase 3 randomised controlled trial 胸膜间皮瘤 (MARS 2) 的扩大胸膜切除术和化学疗法与单纯化学疗法的比较: 一项3期随机对照试验 Lim, Eric; Waller, David; Lau, Kelvin; Steele, Jeremy; Pope, Anthony; Ali, Clinton; Bilancia, Rocco; Keni, Manjusha; Popat, Sanjay; O'Brien, Mary; Tokaca, Nadza; Maskell, Nick; Stadon, Louise; Fennell, Dean; Nelson, Louise; Edwards, John; Tenconi, Sara; Socci, Laura; Rintoul, Robert C.; Wood, Kelly; Stone, Amanda; Muthukumar, Dakshinamoorthy; Ingle, Charlotte; Taylor, Paul; Cove-Smith, Laura; Califano, Raffaele; Summers, Yvonne; Tasigiannopoulos, Zacharias; Bille, Andrea; Shah, Riyaz; Fuller, Elizabeth; Macnair, Andrew; Shamash, Jonathan; Mansy, Talal; Milton, Richard; Koh, Pek; Ionescu, Andreea Alina; Treece, Sarah; Roy, Amy; Middleton, Gary; Kirk, Alan; Harris, Rosie A.; Ashton, Kate; Warnes, Barbara; Bridgeman, Emma; Joyce, Katherine; Mills, Nicola; Elliott, Daisy; Farrar, Nicola; Stokes, Elizabeth; Hughes, Vikki; Nicholson, Andrew G.; Rogers, Chris A. 分享 收藏
The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma 基于人工智能的模型ANORAK改善肺腺癌的组织病理学分级 Pan, Xiaoxi; Abduljabbar, Khalid; Coelho-Lima, Jose; Grapa, Anca-Ioana; Zhang, Hanyun; Cheung, Alvin Ho Kwan; Baena, Juvenal; Karasaki, Takahiro; Wilson, Claire Rachel; Sereno, Marco; Veeriah, Selvaraju; Aitken, Sarah J.; Hackshaw, Allan; Nicholson, Andrew G.; Jamal-Hanjani, Mariam; Swanton, Charles; Jamal-Hanjani, Mariam; Zhang, Hanyun; AbdulJabbar, Khalid; Pan, Xiaoxi; Yuan, Yinyin; Hackshaw, Allan; Le Quesne, John; Veeriah, Selvaraju; Karasaki, Takahiro; Janes, Sam M.; Hacker, Anne-Marie; Sharp, Abigail; Smith, Sean; Dhanda, Harjot Kaur; Chan, Kitty; Pilotti, Camilla; Leslie, Rachel; Grapa, Anca-Ioana; Chuter, David; Mackenzie, Mairead; Chee, Serena; Alzetani, Aiman; Lim, Eric; De Sousa, Paulo; Jordan, Simon; Rice, Alexandra; Raubenheimer, Hilgardt; Bhayani, Harshil; Ambrose, Lyn; Devaraj, Anand; Chavan, Hema; Begum, Sofina; Buderi, Silviu I.; Kaniu, Daniel; Malima, Mpho; Booth, Sarah; Fernandes, Nadia; Shah, Pratibha; Proli, Chiara; Hewish, Madeleine; Danson, Sarah; Shackcloth, Michael J.; Robinson, Lily; Russell, Peter; Blyth, Kevin G.; Kidd, Andrew; Kirk, Alan; Asif, Mo; Bilancia, Rocco; Kostoulas, Nikos; Thomas, Mathew; Nicholson, Andrew G.; Dick, Craig; Lester, Jason F.; Bajaj, Amrita; Nakas, Apostolos; Sodha-Ramdeen, Azmina; Tufail, Mohamad; Scotland, Molly; Boyles, Rebecca; Rathinam, Sridhar; Fennell, Dean A.; Wilson, Claire; Marrone, Domenic; Dulloo, Sean; Matharu, Gurdeep; Shaw, Jacqui A.; Riley, Joan; Primrose, Lindsay; Boleti, Ekaterini; Cheyne, Heather; Khalil, Mohammed; Richardson, Shirley; Cruickshank, Tracey; Price, Gillian; Kerr, Keith M.; Benafif, Sarah; Papadatos-Pastos, Dionysis; Wilson, James; Ahmad, Tanya; French, Jack; Gilbert, Kayleigh; Naidu, Babu; Patel, Akshay J.; Osman, Aya; Lacson, Christer; Langman, Gerald; Shackleford, Helen; Djearaman, Madava; Kadiri, Salma; Middleton, Gary; Leek, Angela; Hodgkinson, Jack Davies; Totten, Nicola; Montero, Angeles; Smith, Elaine; Fontaine, Eustace; Granato, Felice; Novasio, Juliette; Rammohan, Kendadai; Joseph, Leena; Bishop, Paul; Shah, Rajesh; Moss, Stuart; Joshi, Vijay; Crosbie, Philip; Paiva-Correia, Antonio; Chaturvedi, Anshuman; Priest, Lynsey; Oliveira, Pedro; Gomes, Fabio; Brown, Kate; Carter, Mathew; Lindsay, Colin R.; Blackhall, Fiona H.; Krebs, Matthew G.; Summers, Yvonne; Clipson, Alexandra; Tugwood, Jonathan; Kerr, Alastair; Rothwell, Dominic G.; Dive, Caroline; Aerts, Hugo J. W. L.; Schwarz, Roland F.; Kaufmann, Tom L.; Van Loo, Peter; Wilson, Gareth A.; Rosenthal, Rachel; Rowan, Andrew; Bailey, Chris; Lee, Claudia; Colliver, Emma; Enfield, Katey S. S.; Hill, Mark S.; Angelova, Mihaela; Pich, Oriol; Leung, Michelle; Frankell, Alexander M.; Hiley, Crispin T.; Lim, Emilia L.; Zhai, Haoran; Bakir, Maise Al; Birkbak, Nicolai J.; Lucas, Olivia; Huebner, Ariana; Puttick, Clare; Grigoriadis, Kristiana; Dietzen, Michelle; Moore, David A.; Biswas, Dhruva; Athanasopoulou, Foteini; Ward, Sophia; Demeulemeester, Jonas; Castignani, Carla; Cadieux, Elizabeth Larose; Kisistok, Judit; Sokac, Mateo; Szallasi, Zoltan; Diossy, Miklos; Salgado, Roberto; Stewart, Aengus; Magness, Alastair; Weeden, Clare E.; Levi, Dina; Groenroos, Eva; Noorani, Imran; Goldman, Jacki; Escudero, Mickael; Hobson, Philip; Vendramin, Roberto; Boeing, Stefan; Denner, Tamara; Barbe, Vittorio; Lu, Wei-Ting; Hill, William; Naito, Yutaka; Ramsden, Zoe; Kassiotis, George; Dwornik, Angela; Karamani, Angeliki; Chain, Benny; Pearce, David R.; Karagianni, Despoina; Galvez-Cancino, Felip; Stavrou, Georgia; Mastrokalos, Gerasimos; Lowe, Helen L.; Matos, Ignacio Garcia; Reading, James L.; Hartley, John A.; Selvaraju, Kayalvizhi; Chen, Kezhong; Ensell, Leah; Shah, Mansi; Litovchenko, Maria; Chervova, Olga; Pawlik, Piotr; Hynds, Robert E.; Gamble, Samuel; Ung, Seng Kuong Anakin; Bola, Supreet Kaur; Spanswick, Victoria; Wu, Yin; Al-Sawaf, Othman; Jones, Thomas Patrick; Beck, Stephan; Tanic, Miljana; Marafioti, Teresa; Borg, Elaine; Falzon, Mary; Khiroya, Reena; Toncheva, Antonia; Abbosh, Christopher; Richard, Corentin; Naceur-Lombardelli, Cristina; Gimeno-Valiente, Francisco; Thakkar, Krupa; Sunderland, Mariana Werner; Sivakumar, Monica; Kanu, Nnennaya; Prymas, Paulina; Saghafinia, Sadegh; Vanloo, Sharon; Lam, Jie Min; Liu, Wing Kin; Bunkum, Abigail; Hessey, Sonya; Zaccaria, Simone; Martinez-Ruiz, Carlos; Black, James R. M.; Thol, Kerstin; Bentham, Robert; Litchfield, Kevin; Mcgranahan, Nicholas; Quezada, Sergio A.; Forster, Martin D.; Lee, Siow Ming; Herrero, Javier; Nye, Emma; Stone, Richard Kevin; Nicod, Jerome; Rane, Jayant K.; Peggs, Karl S.; Ng, Kevin W.; Dijkstra, Krijn; Huska, Matthew R.; Hoogenboom, Emilie Martinoni; Monk, Fleur; Holding, James W.; Choudhary, Junaid; Bhakhri, Kunal; Scarci, Marco; Gorman, Pat; Stephens, Robert C. M.; Wong, Yien Ning Sophia; Kaplar, Zoltan; Bandula, Steve; Watkins, Thomas B. K.; Veiga, Catarina; Royle, Gary; Collins-Fekete, Charles-Antoine; Fraioli, Francesco; Ashford, Paul; Procter, Alexander James; Ahmed, Asia; Taylor, Magali N.; Nair, Arjun; Lawrence, David; Patrini, Davide; Navani, Neal; Thakrar, Ricky M.; Swanton, Charles; Yuan, Yinyin; Le Quesne, John; Moore, David A. 分享 收藏
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DETERMINE: A pioneering UK precision medicine trial for rare cancers 确定: 英国针对罕见癌症的开创性精密医学试验 Middleton, G.; Marshall, L.; Billingham, L.; Duffus, K. D.; Greystoke, A.; Carter, L.; Forster, M. D.; Cook, N.; Hargrave, D.; Danson, S.; Roxburgh, P.; Beggs, A. D.; Chaturvedi, A.; Chesler, L.; Sarmiento-Castro, A.; Dive, C.; Rothwell, D.; Gath, J.; Halford, S.; Krebs, M. G. 分享 收藏
Novel genetic markers associated with immune checkpoint inhibitor induced immune-related adverse events Chin, I. S.; Mcdonald, L.; Gault, A. C.; Harland, M.; Jolly, C.; Khan, A.; Tong, O.; Sivaswami, M.; Watson, R. A.; Gonzalez-Neira, A.; Papa, S.; Olsson-Brown, A. C.; Williams, K.; Pratt, A.; Newton-Bishop, J.; Cope, A. P.; Middleton, G.; Fairfax, B. P.; Palles, C. 分享 收藏
A population-scale temporal case-control evaluation of COVID-19 disease phenotype and related outcome rates in patients with cancer in England (UKCCP) Starkey, Thomas; Ionescu, Maria; Tilby, Michael; Little, Martin W.; Burke, Emma; Fittall, Matthew; Khan, Sam R.; Liu, Justin K. H.; Platt, James R.; Mew, Rosie; Tripathy, Arvind; Watts, Isabella; Williams, Sophie Therese; Appanna, Nathan; Al-Hajji, Youssra; Barnard, Matthew; Benny, Liza; Burnett, Alexander L.; Bytyci, Jola; Cattell, Emma J.; Cheng, Vinton; Clark, James; Eastlake, Leonie; Gerrand, Kate; Ghafoor, Qamar; Grumett, Simon; Harper-Wynne, Catherine; Kahn, Rachel; Lee, Alvin J. X.; Lomas, Oliver; Lydon, Anna; Mckenzie, Hayley; Kinloch, Emma; Lam, Emily; Murphy, Gillian; Rhodes, Malcolm; Robinson, Kate; Panneerselvam, Hari S.; Pascoe, Jennifer; Patel, Grisma; Patel, Vijay A.; Potter, Vanessa; Randle, Amelia S.; Rigg, Anne M.; Robinson, Tim; Roylance, Rebecca W.; Roques, Tom; Rozmanowski, Stefan; Roux, Rene L.; Shah, Ketan; Sheehan, Remarez; Sintler, Martin; Swarup, Sanskriti; Taylor, Harriet; Tillett, Tania; Tuthill, Mark; Williams, Sarah; Ying, Yuxin; Beggs, Andrew; Iveson, Tim; Lee, Siow Ming; Middleton, Gary; Middleton, Mark; Protheroe, Andrew; Fowler, Tom; Johnson, Peter; Lee, Lennard Y. W.; NCRI Consumer Forum 分享 收藏
Advanced melanoma is associated with distinct circulating B-cell profiles enriched with immunoregulatory and autoreactive features Willsmore, Zena; Crescioli, Silvia; Booth, Lucy; Laddach, Roman; Yorke, Rozalyn; Harris, Robert; Chauhan, Jitesh; Chenoweth, Alicia; Adams, Rebecca; Osborn, Gabriel; Di Meo, Ashley; Prassas, Ioannis; Geh, Jenny L. C.; Patel, Akshay J.; Middleton, Gary W.; MacKenzie Ross, Alastair D.; Healey, Ciaran; Diamandis, Eleftherios P.; Sinha, Khushboo; Wu, Yin; Whittaker, Sean J.; Perucha, Esperanza; Papa, Sophie; Lacy, Katie E.; Karagiannis, Sophia N. 分享 收藏
Spatial determination and prognostic impact of the fibroblast transcriptome in pancreatic ductal adenocarcinoma 成纤维细胞转录组在胰腺导管腺癌中的空间测定和预后影响 Croft, Wayne; Pearce, Hayden; Margielewska-Davies, Sandra; Lim, Lindsay; Nicol, Samantha M.; Zayou, Fouzia; Blakeway, Daniel; Marcon, Francesca; Powell-Brett, Sarah; Mahon, Brinder; Merard, Reena; Zuo, Jianmin; Middleton, Gary; Roberts, Keith; Brown, Rachel M.; Moss, Paul 分享 收藏
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