Mitchell A. Lazar - Publications, H-index & Citations

Mitchell A. Lazar

University of Pennsylvania

138H指数

408论文数

7.2W被引数

收录论文 199

发表时间

Presentation of the AGA Distinguished Achievement Award in Basic Science to Klaus H. Kaestner, PhD 将AGA基础科学杰出成就奖授予Klaus H. Kaestner, PhD

Gastroenterology

IF25.1

2026-09-03

PREAI

Vincent W. Yang; Mitchell A. Lazar; Anil K. Rustgi

You are when you eat: How food synchronizes liver clocks 饮食时间决定一切：食物如何同步肝脏时钟

Science Advances

IF12.5

2026-07-23

OAAI

Qin Zhou; Mitchell A. Lazar

Integrative analyses elucidate transcriptional regulatory functions of risk alleles for metabolic liver disease 整合分析阐明代谢性肝病风险等位基因的转录调控功能

Nature Genetics

IF29

2026-06-02

PREAI

Biying Zhu; Na He; Yang Xiao; Bin Chen; Chen Li; Ravi Mandla; Yifan Liu; Jiayu Zhang; Xiao Chang; Fulong Yu; Marijana Vujkovic; Julie A. Lynch; Kyong-Mi Chang; Bogdan Pasaniuc; Daniel J. Rader; Mitchell A. Lazar; Wenxiang Hu

Author Correction: Circadian circuits control plasticity of group 3 innate lymphoid cells by sustaining epigenetic configuration of RORγt 作者更正: 昼夜节律回路通过维持ror γ t的表观遗传构型来控制第3组先天淋巴样细胞的可塑性

Nature Immunology

IF27.6

2026-03-27

PREAI

Bishan Bhattarai; Alina Ulezko Antonova; Jose L. Fachi; Leone S. Hopkins; Matthew V. D. McCullen; Ankita Saini; Sarah de Oliveira; Wandy L. Beatty; Erik S. Musiek; Vijay K. Kuchroo; Mitchell A. Lazar; Eugene M. Oltz; Marco Colonna

Nuclear receptor coregulator interactions: beyond the switch 核受体共调节因子相互作用：超越开关

GENES & DEVELOPMENT

IF7.7

2026-02-01

PREAI

Bawa, F. Nafrisha Cassim; Lazar, Mitchell A.

Normal circadian period length requires repression of Npas2 by REV-ERB nuclear receptors 正常的昼夜节律周期长度需要REV-ERB核受体对Npas2的抑制

Cell Reports

IF6.9

2025-10-14

OAAI

Michael C. Tackenberg; Kristina M. Heliodoro; Lily C. Melink; Yifan Liu; Kun Zhu; Mitchell A. Lazar

A non-apoptotic caspase-8–meteorin pathway in hepatocytes promotes MASH fibrosis 非凋亡性caspase-8–meteorin通路在肝细胞中促进MASH纤维化

Nature Metabolism

IF20.8

2025-09-26

OAAI

Xiaobo Wang; Mary P. Moore; Hongxue Shi; Yang Xiao; Jiayu Zhang; Lanuza A. P. Faccioli; Zhiping Hu; Shareef Khalid; Danish Saleheen; Dwayne G. Stupack; Tatiana Kisseleva; Alejandro Soto Gutierrez; Mitchell A. Lazar; Ira Tabas

REV-ERBα regulates brain NAD+ levels and tauopathy via an NFIL3–CD38 axis REV-ERBα通过NFIL3–CD38轴调节大脑NAD+水平并影响tauopathy。

Nature Aging

IF19.4

2025-09-01

OAAI

Jiyeon Lee; Ryeonghwa Kang; Sohui Park; Ibrahim O. Saliu; Minsoo Son; Jaymie R. Voorhees; Julie M. Dimitry; Elsa I. Quillin; Lauren N. Woodie; Brian V. Lananna; Li Gan; Young-Ah Goo; Guoyan Zhao; Mitchell A. Lazar; Thomas P. Burris; Erik S. Musiek

Circadian circuits control plasticity of group 3 innate lymphoid cells by sustaining epigenetic configuration of RORγt circadian circuits通过维持RORγt的表观遗传配置来控制group 3 innate lymphoid cells的塑性

Nature Immunology

IF27.6

2025-08-13

PREAI

PSYCHEDELICS AND OCD: TRANSLATIONAL APPROACHES

INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

IF3.7

2025-08-01

OAAI

Lerer, B.; Brownstien, M.; Lazar, M.; Goldstein, P.; Botvinnik, A.; Kozikowski, A.; Lifschytz, T.

Genetic synchronization of the brain and liver molecular clocks defend chrono- metabolic disease 脑和肝脏分子钟的遗传同步化可防御时间-代谢性疾病

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-12-12

OAAI

Woodie, Lauren N.; Alberto, Ahren J.; Krusen, Brianna M.; Melink, Lily C.; Lazar, Mitchell A.

Short-term cold exposure induces persistent epigenomic memory in brown fat

CELL METABOLISM

IF30.9

2024-08-01

PREAI

Inoue, Shin-ichi; Emmett, Matthew J.; Lim, Hee-Woong; Midha, Mohit; Richter, Hannah J.; Celwyn, Isaac J.; Mehmood, Rashid; Chondronikola, Maria; Klein, Samuel; Hauck, Amy K.; Lazar, Mitchell A.

Myeloid-derived miR-6236 potentiates adipocyte insulin signaling and prevents hyperglycemia during obesity

NATURE COMMUNICATIONS

IF15.7

2024-06-25

OAAI

Paneru, Bam D.; Chini, Julia; McCright, Sam J.; Demarco, Nicole; Miller, Jessica; Joannas, Leonel D.; Henao-Mejia, Jorge; Titchenell, Paul M.; Merrick, David M.; Lim, Hee-Woong; Lazar, Mitchell A.; Hill, David A.

Hindbrain REV-ERB nuclear receptors regulate sensitivity to diet-induced obesity and brown adipose tissue pathophysiology 后脑rev-erb核受体调节对饮食诱导的肥胖和棕色脂肪组织病理生理学的敏感性

MOLECULAR METABOLISM

IF6.6

2024-01-01

OAAI

Woodie, Lauren N.; Melink, Lily C.; Alberto, Ahren J.; Burrows, Michelle; Fortin, Samantha M.; Chan, Calvin C.; Hayes, Matthew R.; Lazar, Mitchell A.

Microglial REV-ERBα regulates inflammation and lipid droplet formation to drive tauopathy in male mice (vol, 5197, 2023)

NATURE COMMUNICATIONS

IF15.7

2023-11-27

OAAI

Lee, Jiyeon; Dimitry, Julie M.; Song, Jong Hee; Son, Minsoo; Sheehan, Patrick W.; King, Melvin W.; Tabor, G. Travis; Goo, Young Ah; Lazar, Mitchell A.; Petrucelli, Leonard; Musiek, Erik S.

Cardiomyocyte-specific disruption of the circadian BMAL1-REV-ERBα/β regulatory network impacts distinct miRNA species in the murine heart

COMMUNICATIONS BIOLOGY

IF5.1

2023-11-11

OAAI

Latimer, Mary N.; Williams, Lamario J.; Shanmugan, Gobinath; Carpenter, Bryce J.; Lazar, Mitchell A.; Dierickx, Pieterjan; Young, Martin E.

An intrinsically disordered region controlling condensation of a circadian clock component and rhythmic transcription in the liver

MOLECULAR CELL

IF16.6

2023-10-01

OAAI

Zhu, Kun; Celwyn, Isaac J.; Guan, Dongyin; Xiao, Yang; Wang, Xiang; Hu, Wenxiang; Jiang, Chunjie; Cheng, Lan; Casellas, Rafael; Lazar, Mitchell A.

Novel Roles for the Transcriptional Repressor E4BP4 in Both Cardiac Physiology and Pathophysiology

JACC-BASIC TO TRANSLATIONAL SCIENCE

IF7.2

2023-09-01

OAAI

Mia, Sobuj; Sonkar, Ravi; Williams, Lamario; Latimer, Mary N.; Rawnsley, David R.; Rana, Samir; He, Jin; Dierickx, Pieterjan; Kim, Teayoun; Xie, Min; Habegger, Kirk M.; Kubo, Masato; Zhou, Lufang; Thomsen, Morten B.; Prabhu, Sumanth D.; Frank, Stuart J.; Brookes, Paul S.; Lazar, Mitchell A.; Diwan, Abhinav; Young, Martin E.

Identification of Stage-Specific Hepatocytes That Contribute to Nonalcoholic Steatohepatitis Progression

DIABETES

IF7.5

2023-06-20

PREAI

Xiao, Yang; Zhu, Kun; Liu, Yifan; Lazar, Mitchell A.

The REV-ERB Nuclear Receptors: Timekeepers for the Core Clock Period and Metabolism

ENDOCRINOLOGY

IF3.3

2023-05-07

OAAI

Adlanmerini, Marine; Lazar, Mitchell A.

研究方向