logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
arrow
P

Patrick Y. Wen

mass general brigham cancer institute
H指数:145
被引数:8.7万

个人简介

暂无内容

教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

暂无内容

Neoadjuvant PD1 plus CTLA-4 immune checkpoint blockade in surgically resectable recurrent glioblastoma: a randomized surgical window-of-opportunity trial

新辅助PD1联合CTLA-4免疫检查点阻断在可手术切除的复发性胶质母细胞瘤中的应用：一项随机手术窗口期试验

Nature Communications
IF15.7
2026-09-050
OA
Lu Sun; Lauren F. Markus; Julio C. Sanchez; Thomas J. Lai; Eudocia Quant Lee; Gang Li; Jiyoon Kim; Zian Zhuang; Brenda Acevedo; Richard G. Everson; Ingo K. Mellinghoff; Elisa Aquilanti; L. Nicolas Gonzalez Castro; J. Ricardo McFaline-Figueroa; Lakshmi Nayak; Rameen Beroukhim; Robert A. Chong; Jacqueline Stone; Thomas Kaley; Lauren Schaff; Jessica Wilcox; Catharina Westergaard; Alyssa Russ; Maria Lavallee; Ugonma Chukwueke; Annick D. Van den Abbeele; Michael Lim; Benjamin M. Ellingson; David A. Reardon; Timothy F. Cloughesy; Robert M. Prins; Patrick Y. Wen
The role for surgery in IDH-mutant grade 4 astrocytomas: Interactive effects of resection, patient characteristics, and outcome—Report of the RANO resect group

IDH突变型4级星形细胞瘤中手术的作用：切除、患者特征和预后的交互影响——RANO切除组的报告

Neuro-Oncology
IF13.4
2026-08-310
PRE
Philipp Karschnia; Gilbert Youssef; Jacob S Young; Nico Teske; Maarten M J Wijnenga; Antonio Dono; Okizeva Rapi; Yae Won Park; Arthur Wagner; Tommaso Sciortino; Francesco Bruno; Levin Häni; Felix Ehret; Nicolas Neidert; Einar O Vik-Mo; Roland Goldbrunner; Juergen Beck; Andreas Raabe; Roberta Rudà; Lorenzo Bello; Bernhard Meyer; Sung Soo Ahn; Asgeir S Jakola; Yoshua Esquenazi; Martin van den Bent; Shawn Hervey-Jumper; Mitchel S Berger; Patrick Y Wen; Oliver Schnell; Joerg-Christian Tonn; the RANO resect group
Vorasidenib improves response to subsequent chemoradiation in a genetically engineered mouse model of IDH-mutant glioma

Vorasanib在IDH突变胶质瘤的基因工程小鼠模型中改善了对后续放化疗的反应

Science Translational Medicine
IF14.6
2026-08-050
PRE
Diana D. Shi; Ester Calvo Fernández; Vinesh T. Puliyappadamba; Tyler A. Lanman; Yi Xiao; Zebin Wen; Maria Minor; Diego Prost; Aleksandra B. Lasica; Feng Cai; Ethan Neumann; Sriram Gudipelly; Louise M. Clark; Quang-De Nguyen; Salvador Peña; Janaka Wansapura; Pranita Kaphle; Tracey Shipman; Michael M. Levitt; Mathew D. Lin; Alexander C.-Y. Tsai; Joyce H. Lee; Daniel P. Cahill; Rifaquat Rahman; Daphne A. Haas-Kogan; Timothy E. Richardson; Itay Tirosh; Payal Jain; Adriana E. Tron; Vihang Nakhate; Gilbert Youssef; Caroline Dehais; Julian Jacob; David A. Reardon; Julie J. Miller; Kalil G. Abdullah; Patrick Y. Wen; Ralph J. DeBerardinis; Lin Xu; Mehdi Touat; Katherine B. Peters; L. Nicolas Gonzalez Castro; William G. Kaelin; Mario L. Suvà; Samuel K. McBrayer
Anti-LAG-3 with or without anti-PD-1 in recurrent glioblastoma: a phase 1 trial

抗LAG-3抗体联合或不联合抗PD-1抗体治疗复发性胶质母细胞瘤：一项I期临床试验

Nature Medicine
IF50
2026-07-100
OAAI
Michael Lim; Xiaobu Ye; Anna F. Piotrowski; Arati Desai; Manmeet S. Ahluwalia; Tobias Walbert; Glenn Lesser; Benjamin M. Ellingson; David M. Peereboom; Joy D. Fisher; Serena Desideri; Christina Jackson; Ayush Pant; Aanchal Jain; Rohit Verma; Benjamin Oberlton; Hadeesha Piyadasa; Chetan Bettegowda; Logan Engle; Janis Taube; Sean C. Bendall; John Choi; Jan Drappatz; Frank S. Lieberman; Lawrence R. Kleinberg; Drew M. Pardoll; Louis B. Nabors; Patrick Y. Wen; Stuart A. Grossman
Publisher Correction: Tumor transcriptional state predicts survival in immune-checkpoint-blockade-treated glioblastoma

Publisher Correction: 肿瘤转录状态预测免疫检查点阻断治疗胶质母细胞瘤的生存情况

Nature Cancer
IF28.5
2026-06-120
PRE
Jack Y. Ghannam; Julian Bryan; Jakob Weiss; Daniel Kovarsky; David Merrell; Conor Messer; Kristy Schlueter-Kuck; Geoffrey G. Fell; Mary Jane Lim-Fat; Gilbert Youssef; Rifaquat Rahman; Lei Qin; Geoffrey S. Young; J. Thomas Janes; McKayla Van Orden; Kathleen L. Pfaff; Andrew Gans; Emma S. Lin; Raymond Y. Huang; Brian P. Danysh; Laxmi Parida; Shuqiang Li; Patrick Y. Wen; E. Antonio Chiocca; Donna Neuberg; Keith L. Ligon; Itay Tirosh; David A. Reardon; Gad Getz; Catherine J. Wu
Tumor transcriptional state predicts survival in immune-checkpoint-blockade-treated glioblastoma

肿瘤转录状态预测免疫检查点阻断治疗的胶质母细胞瘤的生存

Nature Cancer
IF28.5
2026-06-030
PRE
Jack Y. Ghannam; Julian Bryan; Jakob Weiss; Daniel Kovarsky; David Merrell; Conor Messer; Kristy Schlueter-Kuck; Geoffrey G. Fell; Mary Jane Lim-Fat; Gilbert Youssef; Rifaquat Rahman; Lei Qin; Geoffrey S. Young; J. Thomas Janes; McKayla Van Orden; Kathleen L. Pfaff; Andrew Gans; Emma S. Lin; Raymond Y. Huang; Brian P. Danysh; Laxmi Parida; Shuqiang Li; Patrick Y. Wen; E. Antonio Chiocca; Donna Neuberg; Keith L. Ligon; Itay Tirosh; David A. Reardon; Gad Getz; Catherine J. Wu
Prognostic significance of O6-methylguanine-DNA methyltransferase promoter methylation status in isocitrate dehydrogenase-mutant glioma
Neuro-Oncology
IF13.4
2025-12-150
PRE
Gilbert Youssef; Elisa Aquilanti; Julie J Miller; Zhou Lan; Aleksandra B Lasica; Isabel Arrillaga-Romany; Tracy T Batchelor; Tamar R Berger; Rameen Beroukhim; Ugonma Chukwueke; Jorg Dietrich; Deborah A Forst; Elizabeth R Gerstner; L Nicolas Gonzalez Castro; Justin T Jordan; J Ricardo Mcfaline-Figueroa; Eudocia Quant Lee; Lakshmi Nayak; Vihang Nakhate; Juan Pablo Ospina; Scott R Plotkin; Nancy Wang; John Y Rhee; David A Reardon; Patrick Y Wen
CTIM-12. DUAL IMMUNE CHECKPOINT BLOCKADE FOR SURGICALLY ACCESSIBLE RECURRENT GLIOBLASTOMA: CLINICAL AND MOLECULAR OUTCOMES

CTIM-12. 双免疫检查点阻断治疗可手术切除的复发性胶质母细胞瘤：临床与分子结局

Neuro-Oncology
IF13.4
2025-11-110
OA
Lu Sun; Eudocia Quant Lee; Gang Li; David A Reardon; Brenda Acevedo; Catharina Westergaard; Alyssa Russ; Richard G Everson; Benjamin M Ellingson; Ingo K Mellinghoff; Elisa Aquilanti; L Nicolas Gonzalez Castro; J Ricardo McFaline-Figueroa; Lakshmi Nayak; Rameen Beroukhim; Robert A Chong; Jacqueline Stone; Thomas Kaley; Lauren Schaff; Jessica wilcox; Maria Lavallee; Ugonma Chukwueke; Annick D Van den Abbeele; Michael Lim; Timothy F Cloughesy; Robert M Prins; Patrick Y Wen
NCOG-43. Clinical outcomes in patients with molecular vs histological glioblastoma

NCOG-43. 分子型与组织学型胶质母细胞瘤患者的临床结局

Neuro-Oncology
IF13.4
2025-11-110
OA
Juan Pablo Ospina; Prem Sai Prabhakar; Catharina Westergaard; Alyssa Russ; Rachel Fox; Ernest Wang; Julia Japo; Julien Rousseau; Vihang Nakhate; Tamar R Berger; John Y Rhee; Elisa Aquilanti; Ugonma N Chukwueke; L Nicolas Gonzalez Castro; Eudocia Q Lee; Lakshmi Nayak; David A Reardon; Raymond Y Huang; Keith L Ligon; Patrick Y Wen; Gilbert Youssef
SAFETY AND TOLERABILITY OF OLAPARIB, TEMOZOLOMIDE, AND PEMBROLIZUMAB IN A PHASE 2 TRIAL IN PATIENTS WITH PROGRESSIVE GLIOBLASTOMA

奥拉帕利、替莫唑胺和帕博利珠单抗在进展性胶质母细胞瘤患者中的II期试验的安全性与耐受性

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Castro, L. Nicolas Gonzalez; McCluskey, Christine; Westergaard, Catharina; Fox, Rachel; Chukwueke, Ugonma; Youssef, Gilbert; Aquilanti, Elisa; Lee, Eudocia; Reardon, David; Arnaout, Omar; Bi, Wenya L.; Peruzzi, Pierpaolo; Golby, Alexandra; Kim, Jiyoon; Vega, Rafael; Schaff, Lauren; Arrillaga-Romany, Isabel; Ligon, Keith; Prins, Robert; Wen, Patrick
UPDATED RESULTS OF PHASE 3 STELLAR TRIAL: EFLORNITHINE IMPROVES OVERALL SURVIVAL AND BLINDED INDEPENDENT CENTRAL REVIEW DETERMINED PROGRESSION FREE SURVIVAL IN PATIENTS WITH RECURRENT WHO 2021 GRADE 3 IDH-MUTANT ASTROCYTOMA

更新后的III期STELLAR试验结果：依氟鸟氨酸改善2021年WHO分级3级IDH突变型星形细胞瘤患者的总生存期和盲态独立中央审查确定的无进展生存期

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Colman, Howard; Lombardi, Giuseppe; Wong, Eric; Walbert, Tobias; Eoli, Marica; Lassman, Andrew; Peereboom, David; Kizilbash, Sani; Kamiya-Matsuoka, Carlos; Pitz, Marshall; Strowd, Roy; Desjardins, Annick; Kumthekar, Priya; Mason, Warren; Pellerino, Alessia; Soffietti, Riccardo; Butowski, Nicholas; Forsyth, Peter; Hamza, Mohamed; Hau, Peter; Lallana, Enrico; Nabors, Burt; Piccioni, David; Uhlmann, Erik; Welsh, Liam; Wen, Patrick; Dietrich, Jorg; Levin, Victor
Multivariate survival risk stratification in GBMs lacking necrosis and microvascular proliferation

胶质母细胞瘤中缺乏坏死和微血管增生的多变量生存风险分层

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Molinaro, Annette; McCoy, Lucie; Warrier, Gayathri; Al-Adli, Nadeem; Young, Jacob S.; Mendez, Joe; Malani, Rachna; Hamel, Elaine; Odell, Jennifer Ledbetter; Eldred, Blaine; Nghiemphu, Phioanh; Liau, Linda M.; Ligon, Keith; Reardon, David A.; Lachance, Daniel; Decker, Paul; Eckel-Passow, Jeanette; Burns, Terry; Kosel, Matthew; Ida, Cristiane; Vaubel, Rachael; Giannini, Caterina; Kollmeyer, Thomas; Kizilbash, Sani; Maqbool, Muhammad Asad; Shafqat, Shameel; Mansouri, Alireza; Jenkins, Robert; Cloughesy, Timothy; Lai, Albert; Youssef, Gilbert; Wen, Patrick; Solomon, David; Chang, Susan; de Groot, John; Colman, Howard
Volumetric (3D) compared with traditional bidirectional (2D) assessment in patients with Grade 2, isocitrate dehydrogenase 1/2 mutant (mIDH1/2) glioma receiving vorasidenib or placebo in the Phase 3 INDIGO trial

与接受vorasidenib或安慰剂治疗的Grade 2，异柠檬酸脱氢酶1/2突变（mIDH1/2）胶质瘤患者中，体素（3D）评估相较于传统双向（2D）评估在INDIGO III期试验中的比较

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Ellingson, Benjamin M.; Mellinghoff, Ingo; Van Den Bent, Martin J.; Blumenthal, Deborah T.; Touat, Mehdi; Peters, Katherine B.; Clarke, Jennifer L.; Mendez, Joe; Yust-Katz, Shlomit; Welsh, Liam; Mason, Warren P.; Ducray, Francois; Umemura, Yoshie; Nabors, Burt; Holdhoff, Matthias; Hottinger, Andreas F.; Arakawa, Yoshiki; Sepulveda, Juan M.; Wick, Wolfgang; Soffietti, Riccardo; Perry, James; Giglio, Pierre; De La Fuente, Macarena, I; Maher, Elizabeth; Zhao, Dan; Pandya, Shuchi S.; Steelman, Lori; Hassan, Islam; Wen, Patrick Y.; Cloughesy, Timothy F.
DEFICITS IN GAIT QUANTIFIED BY LARGE LANGUAGE MODEL-DERIVED NANO SCORES PREDICT SURVIVAL IN HIGH-GRADE GLIOMA

由大型语言模型衍生的Nano评分量化的步态缺陷预测高级别胶质瘤的生存率

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Rhee, John; Tentor, Zachary; Beroukhim, Rameen; Lee, Eudocia; Aquilanti, Elisa; Berger, Tamar; Batchelor, Tracy; Castro, Luis Nicolas Gonzalez; Youssef, Gilbert; Chukwueke, Ugonma; Wen, Patrick; Reardon, David; Lim-Fat, Mary Jane; Lindvall, Charlotta; Nayak, Lakshmi
PHASE 1B SAFETY RESULTS OF VORASIDENIB IN COMBINATION WITH TEMOZOLOMIDE IN PATIENTS WITH MUTANT IDH1 OR IDH2 GLIOMA

1B期试验中，vorasidenib与temozolomide联合治疗携带IDH1或IDH2突变的胶质瘤患者的安全性结果。

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
de la Fuente, Macarena, I; Cloughesy, Timothy F.; Touat, Mehdi; Lopez, Juanita; McBain, Catherine; Steelman, Lori; Hassan, Islam; Jain, Payal; Man, Albert; Abshire, Michelle; Knipstein, Jeffrey; Mellinghoff, Ingo; Wen, Patrick Y.
Preclinical and clinical assessment of chemoradiation after mutant IDH inhibitor treatment in IDH-mutant glioma

IDH突变抑制剂治疗后IDH突变胶质瘤的化学放射治疗预临床与临床评估

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Shi, Diana; Calvo-Fernandez, Ester; Puliyappadamba, Vinesh; Lanman, Tyler; Cruickshank, Aiden; Prost, Diego; Xiao, Yi; Neumann, Ethan; Gudipelly, Sriram; Clark, Louise; Kaphle, Pranita; Shipman, Tracey; Levitt, Michael; Lin, Mathew; Tsai, Alexander; Lee, Joyce; Simons, Donald; Tyagi, Ethika; Rahman, Rifaquat; De Nguyen, Quang-; Wen, Patrick; Haas-Kogan, Daphne; Yates, Kathleen; Manguso, Robert; Bardeesy, Nabeel; Bernstein, Bradley; Wu, Jingyi; Abdullah, Kalil; Jain, Payal; Tron, Adriana; Touat, Mehdi; Castro, L. Nicolas Gonzalez; Suva, Mario; Kaelin, William; Mcbrayer, Samuel

研究方向

暂未获取到该数据
D
David A. Reardon
H 指数:119论文数:1,223被引数:6.2万
T
Timothy F. Cloughesy
H 指数:128论文数:1,355被引数:6.2万
K
Keith L. Ligon
H 指数:113论文数:1,205被引数:5.0万
M
Martin J. van den Bent
H 指数:128论文数:1,361被引数:10.0万
M
Michael Weller
H 指数:175论文数:2,841被引数:16.4万
E
Eudocia Q. Lee
H 指数:52论文数:330被引数:1.4万
T
Tracy T. Batchelor
H 指数:111论文数:943被引数:4.4万
B
Benjamin M. Ellingson
H 指数:65论文数:726被引数:1.7万
B
Brian M. Alexander
H 指数:72论文数:623被引数:1.9万
I
Ingo K. Mellinghoff
H 指数:79论文数:616被引数:3.7万