Chiara Cremolini - Publications, H-index & Citations

Chiara Cremolini

University Hospital of Pisa

65H指数

971论文数

2.0W被引数

收录论文 286

发表时间

Metabolic determinants of cancer immunotherapy outcomes identified by plasma profiling 通过血浆谱分析确定的癌症免疫治疗结果的代谢决定因素

Nature Medicine

IF50

2026-06-25

OAAI

Déborah Suissa; Marine Fidelle; Ella Reich; Thao-Nguyen Pham; Simon Thomas; Johannes R. Björk; Peng Liu; Liwei Zhao; Koji Kitaoka; Eléonore Piard; Isabelle Lebhar; Ai-Ling Tian; Cassandra Thelemaque; Carolina Alves Costa Silva; Eric Deutsch; Yohann Loriot; Nicola Segata; Gianmarco Piccinno; Geke A. P. Hospers; Saman Maleki Vareki; Michael S. Silverman; John G. Lenehan; Véronique Bataille; David Boulate; Tatiana Kuznetsova; Rinse K. Weersma; Meriem Messaoudene; Sylvère Durand; Carlijn M. van der Aalst; Harry J. de Koning; Beatrice Schuler-Thurner; I. Jolanda M. de Vries; Edmond Rafie; Renée Maria Saliby; Marc Machaalani; Sebastian Haferkamp; Bastian Schilling; Serena Porcari; Chiara Ciccarese; Roberto Iacovelli; Chiara Cremolini; Toni K. Choueiri; Arielle Elkrief; Guido Kroemer; Lucie Heinzerling; Kenji Chamoto; Gianluca Ianiro; Bertrand Routy; Lisa Derosa; Nikos Paragios; Laurence Zitvogel

Spatial predictors of response to chemo-immunotherapy in microsatellite stable metastatic colorectal cancer 微卫星稳定型转移性结直肠癌对化疗免疫联合治疗的反应的空间预测因子

Nature Communications

IF15.7

2026-04-25

OAAI

Joan Choo; Joseph J. Zhao; Mai Chan Lau; Alessandra Raimondi; Willa Wen-You Yim; Sruthi Ranganathan; Kexin Zhu; Crystal Tze Ying Tan; Hui Xian Chin; Chong Boon Teo; Khi Yung Fong; Ryan Yong Kiat Tay; Jia-Ying Joey Lee; Lit-Hsin Loo; Paolo Manca; Federica Morano; Michele Prisciandaro; Giovanni Randon; Camilla Damonte; Elisa Micarelli; Guido Leoni; Elisa Scarselli; Sara Lonardi; Chiara Cremolini; Federica Marmorino; Jeffrey Chun Tatt Lim; Zhen Wei Neo; Felicia Wee; Li Yen Chong; Craig Ryan Joseph; Akhila Balachander; Diana GS Lim; You Yi Hwang; Laurent Renia; Subhra Kumar Biswas; David Tan; Joe P. S. Yeong; Raghav Sundar; Filippo Pietrantonio

Tucatinib plus trastuzumab for chemotherapy-refractory, HER2 + , RAS wild-type metastatic colorectal cancer (MOUNTAINEER): final analysis Tucatinib联合曲妥珠单抗治疗化疗难治性、HER2阳性、RAS野生型转移性结直肠癌（MOUNTAINEER）：最终分析

Nature Communications

IF15.7

2026-01-12

OAAI

John H. Strickler; Andrea Cercek; Salvatore Siena; Thierry André; Kimmie Ng; Eric Van Cutsem; Christina Wu; Andrew Scott Paulson; Joleen M. Hubbard; Andrew L. Coveler; Christos Fountzilas; Adel Kardosh; Pashtoon Murtaza Kasi; Heinz-Josef Lenz; Kristen Ciombor; Elena Elez; David L. Bajor; Chiara Cremolini; Federico Sanchez; Mina Nayeri; Wentao Feng; Mark Bieda; Tanios S. Bekaii-Saab

Attenuation-based estimation of myocardial extracellular volume from ECG-ungated whole-body CT examinations as an early biomarker of chemotherapy-induced cardiotoxicity: preliminary findings 基于衰减的心肌细胞外体积估计：从非门控心电图全身CT检查作为化疗诱导的心脏毒性早期生物标志物的初步发现

La radiologia medica

IF4.8

2025-11-18

PREAI

Giovanni Donato Aquaro; Lorenzo Faggioni; Roberto Francischello; Simone Guidi; Maria Livia Del Giudice; Francesca Salani; Riccardo Lencioni; Sara Galimberti; Gianluca Masi; Chiara Cremolini; Emanuele Neri; Dania Cioni

Genomic profiling of high tumor mutational load in microsatellite-stable colorectal cancer uncovers MAPK signaling pathway alterations following anti-EGFR therapy 微卫星稳定型结直肠癌中高肿瘤突变负荷的基因组分析揭示了抗-EGFR治疗后MAPK信号通路的改变

ESMO Open

IF8.3

2025-10-28

OAAI

L. Boscolo Bielo; S. Napolitano; A. Avallone; F. Pietrantonio; R. Bordonaro; E. Maiello; S. Pisconti; E. Tamburini; C. Lotesoriere; G. Tortora; A. Zaniboni; L. Blasi; L. Antonuzzo; R. Berardi; P. Tagliaferri; C. Cremolini; S. Lonardi; C. Garufi; C. Pinto; E. Ongaro; G. Santabarbara; M. Scartozzi; V. De Falco; A. De Stefano; C. Cardone; A. Iacovucci; M.F. Bosco; A.E. Russo; T.P. Latiano; C. Nisi; M. Messina; N. Salmistraro; A. Sartore-Bianchi; S. Siena; M.G. Zampino; N. Fazio; N. Normanno; A. Febbraro; L.P. Guerrera; P. Parente; F. De Vita; E. Martinelli; T. Troiani; G. Curigliano; F. Ciardiello; G. Martini; D. Ciardiello

Chronological survival improvement over time with oxaliplatin-based chemotherapy plus targeted agents in metastatic colorectal cancer: an ARCAD database study 随着奥沙利铂为基础的化疗联合靶向药物，转移性结直肠癌的生存率随时间推移呈逐年改善：一项ARCAD数据库研究

European Journal of Cancer

IF7.1

2025-10-02

OAAI

Kazumasa Yamamoto; Hideaki Bando; Toshihiro Misumi; Tomomi Nishikawa; Masashi Wakabayashi; Kentaro Yamazaki; Yoshihiko Maehara; Eiji Oki; Leonard B Saltz; Jean-Yves Douillard; Cornelis JA Punt; Miriam Koopman; Eric Van Cutsem; Carsten Bokemeyer; Alan P Venook; Volker Heinemann; Chiara Cremolini; J. Randolph Hecht; Hans-Joachim Schmoll; Goro Nakayama; Heinz-Josef Lenz; Thierry Andre; Qian Shi; Aimery de Gramont; Kohei Shitara; Takayuki Yoshino

Genomically matched therapy in advanced solid tumors: the randomized phase 2 ROME trial 基因组匹配疗法在晚期实体瘤中的应用：随机II期ROME试验

Nature Medicine

IF50

2025-09-29

OAAI

Paolo Marchetti; Giuseppe Curigliano; Mauro Biffoni; Sara Lonardi; Simone Scagnoli; Lorenzo Fornaro; Valentina Guarneri; Ugo De Giorgi; Paolo Antonio Ascierto; Giovanni Blandino; Giulia D’Amati; Massimo Aglietta; Chiara Cremolini; Pierfranco Conte; Edoardo Crimini; Maurizio Ceracchi; Simona Pisegna; Sofia Verkhovskaia; Roberto Bordonaro; Sergio Bracarda; Giovanni Butturini; Lucia Del Mastro; Andrea DeCensi; Agnese Fabbri; Elisabetta Fenocchio; Stefania Gori; Giulio Metro; Annamaria Pessino; Daniele Pozzessere; Fabio Puglisi; Stefano Tamberi; Alberto Zambelli; Donatella Marino; Ettore Capoluongo; Federico Cappuzzo; Bruna Cerbelli; Giuseppe Giannini; Umberto Malapelle; Federica Mazzuca; Marianna Nuti; Giancarlo Pruneri; Maurizio Simmaco; Lidia Strigari; Giuseppe Tonini; Nello Martini; Andrea Botticelli

Early-onset colorectal cancer patients exhibit a distinct molecular fingerprint: insights from a large-scale NGS study of 1209 patients 早发性结直肠癌患者表现出独特的分子特征：来自一项包含1209例患者的全基因组测序研究的见解

ESMO Open

IF8.3

2025-09-01

OAAI

A. Pretta; V. Nasca; F. Marmorino; R. Intini; P. Ziranu; G. Randon; M. Carullo; K. Cerma; C. Donisi; C. Damonte; A. Taravella; C. Gaiani; G. Pretta; V. Pusceddu; I. Montroni; P. Ciracì; A. De Rosa; F. Bergamo; S. Lonardi; C. Cremolini; F. Pietrantonio; M. Scartozzi

Primary tumor sidedness and negative hyperselection to modulate anti-EGFR-based maintenance strategies in patients with RAS wild-type metastatic colorectal cancer: individual patient data pooled analysis of two randomized clinical trials 原发肿瘤侧别及负超选择对RAS野生型转移性结直肠癌患者抗EGFR为基础维持疗法的影响：两项随机临床试验的个体患者数据合并分析

British Journal of Cancer

IF6.8

2025-08-28

OAAI

Alexej Ballhausen; Federica Morano; Arndt Stahler; Sara Lonardi; Andreas Jay Kind; Chiara Cremolini; Susanna Swoboda; Giovanni Randon; David Horst; Michele Prisciandaro; Annabel Helga Sophie Alig; Chiara Carlotta Pircher; Armin Jarosch; Paola Andena; Annika Kurreck; Anna Alessandra Chiaramonte; Sebastian Stintzing; Filippo Pietrantonio; Dominik Paul Modest; Alessandra Raimondi

FOLFOXIRI/bevacizumab versus doublets/bevacizumab as initial therapy of unresectable liver-only, right-sided and/or RAS or BRAF mutated metastatic colorectal cancer: an individual patient data-based pooled analysis of randomized trials FOLFOXIRI/bevacizumab与双药/bevacizumab作为不可切除的肝-only、右侧和/或RAS或BRAF突变转移性结直肠癌初始治疗的比较：一项基于个体患者数据的随机试验合并分析

European Journal of Cancer

IF7.1

2025-08-15

PREAI

Carlotta Antoniotti; Federica Marmorino; Daniele Rossini; Hans Joachim Schmoll; Sara Lonardi; Giuseppe Tonini; Beatrice Borelli; Samanta Cupini; Alexander Stein; Roberto Moretto; Francesca Bergamo; Monica Ronzoni; Marco Maria Germani; Alberto Zaniboni; Roberta Fazio; Maria Caterina De Grandis; Elena Ongaro; Gianluca Masi; Chiara Cremolini

lancet oncology

IF0

2025-08-11

OAAI

Dominik Paul Modest; Marwan Fakih; Lisa Salvatore; Taito Esaki; David Páez Lopez-Bravo; Julien Taieb; Michalis Karamouzis; Erika Ruiz-Garcia; Tae Won Kim; Yasutoshi Kuboki; Fausto Meriggi; David Cunningham; Kun-Huei Yeh; Chiara Cremolini; Qui Tran; Emily Chan; Joseph Chao; Istvan Matyas Majer; Filippo Pietrantonio

FOLFIRINOX or FOLFOX for locally advanced or metastatic small bowel adenocarcinoma: PRODIGE 86 – FFCD-GONO – ENGIC 02 – FOLFIRINOX SBA phase II randomized trial FOLFIRINOX或FOLFOX用于局部晚期或转移性小肠腺癌：PRODIGE 86 – FFCD-GONO – ENGIC 02 – FOLFIRINOX SBA II期随机试验

Digestive and Liver Disease

IF3.8

2025-07-28

OAAI

Thomas Aparicio; Anthony Turpin; Aziz Zaanan; Christelle de la Fouchardière; Karine Le Malicot; Sara Lonardi; Dominik Paul Modest; Richard Wilson; Chiara Cremolini; Alexej Ballhausen; Janet Graham; Annika Kurreck; Meriem Guarssifi; Magali Svrcek; Pierre Laurent-Puig; Sylvain Manfredi

Fruquintinib in less pretreated patients: multivariate profile-matching analysis of FRESCO-2 to FRESCO fruquintinib 在较少预治疗患者中的研究：FRESCO-2 与 FRESCO 的多变量配型匹配分析

European Journal of Cancer

IF7.1

2025-07-13

OAAI

Arvind Dasari; Cathy Eng; Sara Lonardi; Rocio Garcia-Carbonero; Toshiki Masuishi; Chiara Cremolini; François Ghiringhelli; Joleen Hubbard; Tanios Bekaii-Saab; Jeremy Jones; Rui-Hua Xu; Lin Shen; Jianming Xu; Yuxian Bai; Yanhong Deng; Ying Yuan; Wei Wei; Jianchang Lin; Lucy Chen; Zhao Yang; Jin Li

Prognostic impact of the BRAF V600E mutation in patients with MSI-high metastatic colorectal cancer treated with immune checkpoint inhibitors MSI-High结直肠癌患者接受免疫检查点抑制剂治疗后BRAF V600E突变对预后的影响

European Journal of Cancer

IF7.1

2025-07-12

PREAI

Claire Gallois; Margherita Ambrosini; Sara Lonardi; Emily Alouani; Rosine Guimbaud; Michael J. Overman; Frank Sinicrope; Thibault Mazard; Marie Decraecker; Javier Ros; Elena Elez; Simon Pernot; Chiara Cremolini; Alice Boilève; Pauline Parent; Priya Jayachandran; Marie Dutherage; Mathilde Mercier; Clémence Flecchia; Marwan Fakih; Francesco Sclafani; Filippo Pietrantonio; Julien Taieb; David Tougeron

Integrating tissue and liquid biopsy comprehensive genomic profiling to predict efficacy of anti-EGFR therapies in metastatic colorectal cancer: Findings from the CAPRI-2 GOIM study 整合组织与液体活检综合基因组分析以预测抗EGFR疗法在转移性结直肠癌中的疗效：CAPRI-2 GOIM研究的结果

European Journal of Cancer

IF7.1

2025-07-12

PREAI

Davide Ciardiello; Luca Boscolo Bielo; Stefania Napolitano; Eleonora Cioli; Tiziana Pia Latiano; Alfonso De Stefano; Emiliano Tamburini; Matteo Ramundo; Roberto Bordonaro; Alessia Erika Russo; Salvatore Pisconti; Claudia Nisi; Claudio Lotesoriere; Simona Vallarelli; Sara Lonardi; Viola Barruca; Chiara Cremolini; Giampaolo Tortora; Pierosandro Tagliaferri; Filippo Pietrantonio; Giulia Martini

The relative dose intensity of first-line FOLFOXIRI and FOLFOX/FOLFIRI both in combination with bevacizumab affects prognosis of metastatic colorectal cancer patients: A pooled analysis of TRIBE and TRIBE2 studies FOLFOXIRI和FOLFOX/FOLFIRI两种一线方案，无论是否联合贝伐珠单抗，其相对剂量强度均会影响转移性结直肠癌患者的预后：TRIBE和TRIBE2研究的合并分析

EUROPEAN JOURNAL OF CANCER

IF7.1

2025-06-01

PREAI

Moretto, R.; Rossini, D.; Polito, Mariam Grazia; Antoniotti, Carlotta; Intini, Rossana; Conca, Veronica; Andena, Paola; Carullo, Martina; Salvatore, Lisa; Germani, Marco Maria; Bergamo, Francesca; Passardi, Alessandro; Ciraci, Paolo; Tamburini, Emiliano; Boccaccio, Chiara; Zaniboni, Alberto; Masi, Gianluca; Pietrantonio, Filippo; Lonardi, Sara; Cremolini, C.

Promoting large multinational academic clinical trials for gastrointestinal cancers in Europe: the ENGIC (European Network for GI Cancers) initiative 促进欧洲胃肠道癌症大型跨国学术临床研究：ENGIC（欧洲胃肠道癌症网络）倡议

ESMO OPEN

IF8.3

2025-05-01

OAAI

Taieb, J.; Seligmann, J.; Modest, D.; Girault, C.; Rivera, F.; Mahillo, E.; Osterlund, P.; Pfeiffer, P.; Malka, D.; Louvet, C.; Siebenhuner, A. R.; Morf, C.; de la Fouchardiere, C.; Monard, L.; Koopman, M.; Vink, G.; Borbath, I.; Dewever, L.; Adams, R.; Reinacher-Schick, A.; Pietrantonio, F.; Lonardi, S.; Aparicio, T.; Cremolini, C.

Surrogate markers of intestinal dysfunction associated with survival in advanced cancers 与晚期癌症生存相关的肠道功能障碍的替代标志物

OncoImmunology

IF6.3

2025-04-06

OAAI

Roxanne Birebent; Damien Drubay; Carolina Alves Costa Silva; Federica Marmorino; Giacomo Vitali; Gianmarco Piccinno; Yoan Hurtado; Adele Bonato; Lorenzo Belluomini; Meriem Messaoudene; Bertrand Routy; Marine Fidelle; Gerard Zalcman; Julien Mazieres; Clarisse Audigier-Valette; Denis Moro-Sibilot; François Goldwasser; Arnaud Scherpereel; Hervé Pegliasco; François Ghiringhelli; Anna Reni; Fabrice Barlesi; Laurence Albiges; David Planchard; Stéphanie Martinez; Benjamin Besse; Nicola Segata; Chiara Cremolini; Laurence Zitvogel; Valerio Iebba; Lisa Derosa

Comprehensive genomic profiling by liquid biopsy portrays metastatic colorectal cancer mutational landscape to predict antitumor efficacy of FOLFIRI plus cetuximab in the CAPRI-2 GOIM trial 液体活检综合基因组分析描绘了转移性结直肠癌的突变景观，以预测CAPRI-2 GOIM试验中FOLFIRI联合西妥昔单抗的抗肿瘤疗效。

ESMO OPEN

IF8.3

2025-04-01

PREAI

Ciardiello, D.; Bielo, L. B.; Napolitano, S.; Latiano, T. P.; De Stefano, A.; Tamburini, E.; Toma, I.; Bordonaro, R.; Russo, A. E.; Pisconti, S.; Nisi, C.; Lotesoriere, C.; Vallarelli, S.; Lonardi, S.; Iacono, D.; Cremolini, C.; Tortora, G.; Tagliaferri, P.; Pietrantonio, F.; Rosati, G.; Lucenti, A.; Scartozzi, M.; Brunetti, O.; Cinieri, S.; Zampino, M. G.; Zaniboni, A.; Berardi, R.; Paoletti, G.; Febbraro, A.; Martinelli, E.; Troiani, T.; Cioli, E.; Normanno, N.; Di Maio, M.; Parente, P.; Fazio, N.; Curigliano, G.; De Vita, F.; Avallone, A.; Maiello, E.; Ciardiello, F.; Martini, G.

Liver metastases do not predict resistance to the addition of atezolizumab to first-line FOLFOXIRI plus bevacizumab in proficient MMR metastatic colorectal cancer: a secondary analysis of the AtezoTRIBE study

ESMO OPEN

IF8.3

2025-02-01

OAAI

Antoniotti, C.; Carullo, M.; Rossini, D.; Pietrantonio, F.; Salvatore, L.; Lonardi, S.; Tamberi, S.; Sciortino, C.; Conca, V.; Calegari, M. A.; Ciraci, P.; Tamburini, E.; Bergamo, F.; Boccaccio, C.; Passardi, A.; Ritorto, G.; Ugolini, C.; Aprile, G.; Galon, J.; Cremolini, C.

研究方向