Victoria H. Cowling - Publications, H-index & Citations

Victoria H. Cowling

Cancer Research UK Scotland Institute

35H指数

81论文数

3.9K被引数

收录论文 48

发表时间

CMTR1 directs mitochondrial dynamics during T cell activation through epitranscriptomic regulation of splice isoforms CMTR1通过表观转录组学调控剪接异构体，在T细胞活化期间调控线粒体动力学。

Cell Reports

IF6.9

2025-10-13

OAAI

Alison Galloway; Katarzyna Knop; Carolina Gomez-Moreira; Vanessa Xavier; Sarah Thomson; Harunori Yoshikawa; Olga Suska; Radoslaw Lukoszek; Aneesa Kaskar; Angus I. Lamond; Thomas MacVicar; Victoria H. Cowling

Characterisation of RNA guanine-7 methyltransferase (RNMT) using a small molecule approach

BIOCHEMICAL JOURNAL

IF4.3

2025-02-17

OAAI

Pearson, Lesley-Anne; Petit, Alain-Pierre; Martinez, Cesar Mendoza; Bellany, Fiona; Lin, De; Niven, Sarah; Swift, Rachel; Eadsforth, Thomas; Fyfe, Paul; Paul, Marilyn; Postis, Vincent; Hu, Xiao; Cowling, Victoria H.; Gray, David W.

The Cap- proximal secondary structures of the 5′UTRs of parainfluenza virus 5 mRNAs specify differential sensitivity to type I interferon and IFIT1

JOURNAL OF GENERAL VIROLOGY

IF4.3

2025-01-01

PREAI

Hankinson, Jacqueline; Young, Dan; Wignall-Fleming, Elizabeth B.; Lukoszek, Radoslaw; Cowling, Victoria H.; Randall, Richard; Goodbourn, Steve

Mitochondrial double-stranded RNA homeostasis depends on cell-cycle progression

LIFE SCIENCE ALLIANCE

IF2.9

2024-08-29

OAAI

Xavier, Vanessa; Martinelli, Silvia; Corbyn, Ryan; Pennie, Rachel; Rakovic, Kai; Powley, Ian R.; Officer-Jones, Leah; Ruscica, Vincenzo; Galloway, Alison; Carlin, Leo M.; Cowling, Victoria H.; Le Quesne, John; Martinou, Jean-Claude; Macvicar, Thomas

CK2 phosphorylation of CMTR1 promotes RNA cap formation and influenza virus infection

CELL REPORTS

IF6.9

2024-07-01

OAAI

Lukoszek, Radoslaw; Inesta-Vaquera, Francisco; Brett, Natasha J. M.; Liang, Shang; Hepburn, Lydia A.; Hughes, David J.; Pirillo, Chiara; Roberts, Edward W.; Cowling, Victoria H.

The RNA cap methyltransferases RNMT and CMTR1 co-ordinate gene expression during neural differentiation

BIOCHEMICAL SOCIETY TRANSACTIONS

IF4.3

2023-05-05

OAAI

Liang, Shang; Almohammed, Rajaei; Cowling, Victoria H.

A conserved Myc protein domain, MBIV, regulates DNA binding, apoptosis, transformation, an G2 arrest

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

112

OAAI

Cowling, Victoria H.; Chandriani, Sanjay; Whitfield, Michael L.; Cole, Michael D.

The Myc transactivation domain promotes global phosphorylation of the RNA polymerase II carboxy-terminal domain independently of direct DNA binding

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

147

OAAI

Cowling, Victoria H.; Cole, Michael D.

c-Myc transforms human mammary epithelial cells through repression of the Wnt inhibitors DKK1 and SFRP1

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

107

OAAI

Cowling, Victoria H.; D'Cruz, Celina M.; Chodosh, Lewis A.; Cole, Michael D.

S-Adenosyl Homocysteine Hydrolase Is Required for Myc-Induced mRNA Cap Methylation, Protein Synthesis, and Cell Proliferation

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-21

OAAI

Fernandez-Sanchez, Maria Elena; Gonatopoulos-Pournatzis, Thomas; Preston, Gavin; Lawlor, Margaret A.; Cowling, Victoria H.

CMTR1 is recruited to transcription start sites and promotes ribosomal protein and histone gene expression in embryonic stem cells

NUCLEIC ACIDS RESEARCH

IF13.1

2022-02-25

OAAI

Liang, Shang; Silva, Joana C.; Suska, Olga; Lukoszek, Radoslaw; Almohammed, Rajaei; Cowling, Victoria H.

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase

BIOCHEMICAL JOURNAL

IF4.3

2021-07-02

OAAI

Basu, Souradeep; Mak, Tiffany; Ulferts, Rachel; Wu, Mary; Deegan, Tom; Fujisawa, Ryo; Tan, Kang Wei; Lim, Chew Theng; Basier, Clovis; Canal, Berta; Curran, Joseph F.; Drury, Lucy S.; McClure, Allison W.; Roberts, Emma L.; Weissmann, Florian; Zeisner, Theresa U.; Beale, Rupert; Cowling, Victoria H.; Howell, Michael; Labib, Karim; Diffley, John F. X.

Upregulation of RNA cap methyltransferase RNMT drives ribosome biogenesis during T cell activation

NUCLEIC ACIDS RESEARCH

IF13.1

2021-06-14

OAAI

Galloway, Alison; Kaskar, Aneesa; Ditsova, Dimitrinka; Atrih, Abdelmadjid; Yoshikawa, Harunori; Gomez-Moreira, Carolina; Suska, Olga; Warminski, Marcin; Grzela, Renata; Lamond, Angus, I; Darzynkiewicz, Edward; Jemielity, Jacek; Cowling, Victoria H.

A novel RNA pol II CTD interaction site on the mRNA capping enzyme is essential for its allosteric activation

NUCLEIC ACIDS RESEARCH

IF13.1

2021-03-03

OAAI

Bage, Marcus G.; Almohammed, Rajaei; Cowling, Victoria H.; Pisliakov, Andrei, V

The eukaryotic translation initiation factor eIF4E elevates steady-state m7G capping of coding and noncoding transcripts

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-10-14

OAAI

Culjkovic-Kraljacic, Biljana; Skrabanek, Lucy; Revuelta, Maria V.; Gasiorek, Jadwiga; Cowling, Victoria H.; Cerchietti, Leandro; Borden, Katherine L. B.

Direct High-Throughput Screening Assay for mRNA Cap Guanine-N7 Methyltransferase Activity

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2020-08-10

OAAI

Kasprzyk, Renata; Fido, Mateusz; Mamot, Adam; Wanat, Przemyslaw; Smietanski, Miroslaw; Kopcial, Michal; Cowling, Victoria H.; Kowalska, Joanna; Jemielity, Jacek

Mechanism of allosteric activation of human mRNA cap methyltransferase (RNMT) by RAM: insights from accelerated molecular dynamics simulations RAM对人mRNA帽甲基转移酶 (RNMT) 的变构激活机制: 来自加速分子动力学模拟的见解

NUCLEIC ACIDS RESEARCH

IF13.1

2019-07-22

OAAI

Bueren-Calabuig, Juan A.; Bage, Marcus G.; Cowling, Victoria H.; Pisliakov, Andrei V.

CAPAM: The mRNA Cap Adenosine N6-Methyltransferase

TRENDS IN BIOCHEMICAL SCIENCES

IF11

2019-03-01

OAAI

Cowling, Victoria H.

DHX15 regulates CMTR1-dependent gene expression and cell proliferation

LIFE SCIENCE ALLIANCE

IF2.9

2018-06-18

OAAI

Inesta-Vaquera, Francisco; Chaugule, Viduth K.; Galloway, Alison; Chandler, Laurel; Rojas-Fernandez, Alejandro; Weidlich, Simone; Peggie, Mark; Cowling, Victoria H.

Positioning Europe for the EPITRANSCRIPTOMICS challenge

RNA BIOLOGY

IF3.4

2018-05-09

OAAI

Jantsch, Michael F.; Quattrone, Alessandro; O'Connell, Mary; Helm, Mark; Frye, Michaela; Macias-Gonzales, Manuel; Ohman, Marie; Ameres, Stefan; Willems, Luc; Fuks, Francois; Oulas, Anastasis; Vanacova, Stepanka; Nielsen, Henrik; Bousquet-Antonelli, Cecile; Motorin, Yuri; Roignant, Jean-Yves; Balatsos, Nikolaos; Dinnyes, Andras; Baranov, Pavel; Kelly, Vincent; Lamm, Ayelet; Rechavi, Gideon; Pelizzola, Mattia; Liepins, Janis; Kholodnyuk, Irina Holodnuka; Zammit, Vanessa; Ayers, Duncan; Drablos, Finn; Dahl, John Arne; Bujnicki, Janusz; Jeronimo, Carmen; Almeida, Raquel; Neagu, Monica; Costache, Marieta; Bankovic, Jasna; Banovic, Bojana; Kyselovic, Jan; Valor, Luis Miguel; Selbert, Stefan; Pir, Pinar; Demircan, Turan; Cowling, Victoria; Schaefer, Matthias; Rossmanith, Walter; Lafontaine, Denis; David, Alexandre; Carre, Clement; Lyko, Frank; Schaffrath, Raffael; Schwartz, Schraga; Verdel, Andre; Klungland, Arne; Purta, Elzbieta; Timotijevic, Gordana; Cardona, Fernando; Davalos, Alberto; Ballana, Ester; O'Carroll, Donal; Ule, Jernej; Fray, Rupert

研究方向