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J

John T. Poirier

Memorial Sloan Kettering Cancer Center
H指数:58
被引数:1.6万

个人简介

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教育背景

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工作经历

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荣誉奖项

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Deep mutational scanning reveals EGFR mutations conferring resistance to the 4th-generation EGFR tyrosine kinase inhibitor BLU-945

深度突变扫描揭示了赋予对第四代EGFR酪氨酸激酶抑制剂BLU-945耐药性的EGFR突变。

npj Precision Oncology
IF8
2025-08-200
OAAI
Yueyang Wang; Yuan Hao; Michela Ranieri; Tigran M. Abramyan; Lev Tsidilkovski; Michelle Hollenberg; Alfonso Lopez; Xavier T. R. Moore; Fiona Sherman; Jiehui Deng; Hayk Saribekyan; Garegin Papoian; Kwok-Kin Wong; Elaine Shum; John T. Poirier
Glutamine antagonist DRP-104 suppresses tumor growth and enhances response to checkpoint blockade in KEAP1 mutant lung cancer
SCIENCE ADVANCES
IF12.5
2024-03-2910
OAAI
Pillai, Ray; LeBoeuf, Sarah E.; Hao, Yuan; New, Connie; Blum, Jenna L. E.; Rashidfarrokhi, Ali; Huang, Shih Ming; Bahamon, Christian; Wu, Warren L.; Karadal-Ferrena, Burcu; Herrera, Alberto; Ivanova, Ellie; Cross, Michael; Bossowski, Jozef P.; Ding, Hongyu; Hayashi, Makiko; Rajalingam, Sahith; Karakousi, Triantafyllia; Sayin, Volkan I.; Khanna, Kamal M.; Wong, Kwok-Kin; Wild, Robert; Tsirigos, Aristotelis; Poirier, John T.; Rudin, Charles M.; Davidson, Shawn M.; Koralov, Sergei B.; Papagiannakopoulos, Thales
Inflammation in the tumor-adjacent lung as a predictor of clinical outcome in lung adenocarcinoma
NATURE COMMUNICATIONS
IF15.7
2023-11-084
OAAI
Dolgalev, Igor; Zhou, Hua; Murrell, Nina; Le, Hortense; Sakellaropoulos, Theodore; Coudray, Nicolas; Zhu, Kelsey; Vasudevaraja, Varshini; Yeaton, Anna; Goparaju, Chandra; Li, Yonghua; Sulaiman, Imran; Tsay, Jun-Chieh J.; Meyn, Peter; Mohamed, Hussein; Sydney, Iris; Shiomi, Tomoe; Ramaswami, Sitharam; Narula, Navneet; Kulicke, Ruth; Davis, Fred P.; Stransky, Nicolas; Smolen, Gromoslaw A.; Cheng, Wei-Yi; Cai, James; Punekar, Salman; Velcheti, Vamsidhar; Sterman, Daniel H.; Poirier, J. T.; Neel, Ben; Wong, Kwok-Kin; Chiriboga, Luis; Heguy, Adriana; Papagiannakopoulos, Thales; Nadorp, Bettina; Snuderl, Matija; Segal, Leopoldo N.; Moreira, Andre L.; Pass, Harvey I.; Tsirigos, Aristotelis
KEAP1 mutation in lung adenocarcinoma promotes immune evasion and immunotherapy resistance
CELL REPORTS
IF6.9
2023-11-0132
OAAI
Zavitsanou, Anastasia -Maria; Pillai, Ray; Hao, Yuan; Wu, Warren L.; Bartnicki, Eric; Karakousi, Triantafyllia; Rajalingam, Sahith; Herrera, Alberto; Karatza, Angeliki; Rashidfarrokhi, Ali; Solis, Sabrina; Ciampricotti, Metamia; Yeaton, Anna H.; Ivanova, Ellie; Wohlhieter, Corrin A.; Buus, Terkild B.; Hayashi, Makiko; Karadal-Ferrena, Burcu; Pass, Harvey I.; Poirier, John T.; Rudin, Charles M.; Wong, Kwok-Kin; Moreira, Andre L.; Khanna, Kamal M.; Tsirigos, Aristotelis; Papagiannakopoulos, Thales; Koralov, Sergei B.
cfDNA methylome profiling for detection and subtyping of small cell lung cancers

用于检测和分型小细胞肺癌的cfDNA甲基化谱

NATURE CANCER
IF28.5
2022-08-0858
OAAI
Chemi, Francesca; Pearce, Simon P.; Clipson, Alexandra; Hill, Steven M.; Conway, Alicia-Marie; Richardson, Sophie A.; Kamieniecka, Katarzyna; Caeser, Rebecca; White, Daniel J.; Mohan, Sumitra; Foy, Victoria; Simpson, Kathryn L.; Galvin, Melanie; Frese, Kristopher K.; Priest, Lynsey; Egger, Jacklynn; Kerr, Alastair; Massion, Pierre P.; Poirier, John T.; Brady, Gerard; Blackhall, Fiona; Rothwell, Dominic G.; Rudin, Charles M.; Dive, Caroline
Delta-like ligand 3-targeted radioimmunotherapy for neuroendocrine prostate cancer

Delta样配体3靶向放射免疫治疗神经内分泌前列腺癌

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2022-06-2725
OAAI
Korsen, Joshua A.; Gutierrez, Julia A.; Tully, Kathryn M.; Carter, Lukas M.; Samuels, Zachary, V; Khitrov, Samantha; Poirier, John T.; Rudin, Charles M.; Chen, Yu; Morris, Michael J.; Bodei, Lisa; Pillarsetty, Nagavarakishore; Lewis, Jason S.
Genomic and transcriptomic analysis of a library of small cell lung cancer patient-derived xenografts
NATURE COMMUNICATIONS
IF15.7
2022-04-1931
OAAI
Caeser, Rebecca; Egger, Jacklynn, V; Chavan, Shweta; Socci, Nicholas D.; Jones, Caitlin Byrne; Kombak, Faruk Erdem; Asher, Marina; Roehrl, Michael H.; Shah, Nisargbhai S.; Allaj, Viola; Manoj, Parvathy; Tischfield, Sam E.; Kulick, Amanda; Meneses, Maximiliano; Iacobuzio-Donahue, Christine A.; Lai, W. Victoria; Bhanot, Umeshkumar; Baine, Marina K.; Rekhtman, Natasha; Hollmann, Travis J.; de Stanchina, Elisa; Poirier, John T.; Rudin, Charles M.; Sen, Triparna
Inhibition of XPO1 Sensitizes Small Cell Lung Cancer to First- and Second-Line Chemotherapy
CANCER RESEARCH
IF16.6
2022-02-0228
OA
Quintanal-Villalonga, Alvaro; Taniguchi, Hirokazu; Hao, Yuan; Chow, Andrew; Zhan, Yingqian A.; Chavan, Shweta S.; Uddin, Fathema; Allaj, Viola; Manoj, Parvathy; Shah, Nisargbhai S.; Chan, Joseph M.; Offin, Michael; Ciampricotti, Metamia; Ray-Kirton, Jordana; Egger, Jacklynn; Bhanot, Umesh; Linkov, Irina; Asher, Marina; Roehrl, Michael H.; Qiu, Juan; de Stanchina, Elisa; Hollmann, Travis J.; Koche, Richard P.; Sen, Triparna; Poirier, John T.; Rudin, Charles M.
Multiomic Analysis of Lung Tumors Defines Pathways Activated in Neuroendocrine Transformation
CANCER DISCOVERY
IF33.3
2021-12-0289
OA
Quintanal-Villalonga, Alvaro; Taniguchi, Hirokazu; Zhan, Yingqian A.; Hasan, Maysun M.; Chavan, Shweta S.; Meng, Fanli; Uddin, Fathema; Manoj, Parvathy; Donoghue, Mark T. A.; Won, Helen H.; Chan, Joseph M.; Ciampricotti, Metamia; Chow, Andrew; Offin, Michael; Chang, Jason C.; Ray-Kirton, Jordana; Tischfield, Sam E.; Egger, Jacklynn, V; Bhanot, Umesh K.; Linkov, Irina; Asher, Marina; Sinha, Sonali; Silber, Joachim; Iacobuzio-Donahue, Christine A.; Roehrl, Michael H.; Hollmann, Travis J.; Yu, Helena A.; Qiu, Juan; de Stanchina, Elisa; Baine, Marina K.; Rekhtman, Natasha; Poirier, John T.; Loomis, Brian; Koche, Richard P.; Rudin, Charles M.; Sen, Triparna
Rlf-Mycl Gene Fusion Drives Tumorigenesis and Metastasis in a Mouse Model of Small Cell Lung Cancer
CANCER DISCOVERY
IF33.3
2021-12-0226
OA
Ciampricotti, Metamia; Karakousi, Triantafyllia; Richards, Allison L.; Quintanal-Villalonga, Alvaro; Karatza, Angeliki; Caeser, Rebecca; Costa, Emily A.; Allaj, Viola; Manoj, Parvathy; Spainhower, Kyle B.; Kombak, Faruk E.; Sanchez-Rivera, Francisco J.; Jaspers, Janneke E.; Zavitsanou, Anastasia-Maria; Maddalo, Danilo; Ventura, Andrea; Rideout, William M.; Akama-Garren, Elliot H.; Jacks, Tyler; Donoghue, Mark T. A.; Sen, Triparna; Oliver, Trudy G.; Poirier, John T.; Papagiannakopoulos, Thales; Rudin, Charles M.
A CRISPR Activation Screen Identifies an Atypical Rho GTPase That Enhances Zika Viral Entry
VIRUSES-BASEL
IF3.5
2021-10-2012
OAAI
Luu, Anh Phuong; Yao, Zhenlan; Ramachandran, Sangeetha; Azzopardi, Stephanie A.; Miles, Linde A.; Schneider, William M.; Hoffmann, H. -Heinrich; Bozzacco, Leonia; Garcia, Gustavo; Gong, Danyang; Damoiseaux, Robert; Tang, Hengli; Morizono, Kouki; Rudin, Charles M.; Sun, Ren; Arumugaswami, Vaithilingaraja; Poirier, John T.; MacDonald, Margaret R.; Rice, Charles M.; Li, Melody M. H.
ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1-mutant lung cancer
NATURE CANCER
IF28.5
2021-05-1787
OAAI
Deng, Jiehui; Thennavan, Aatish; Dolgalev, Igor; Chen, Ting; Li, Jie; Marzio, Antonio; Poirier, John T.; Peng, David H.; Bulatovic, Mirna; Mukhopadhyay, Subhadip; Silver, Heather; Papadopoulos, Eleni; Pyon, Val; Thakurdin, Cassandra; Han, Han; Li, Fei; Li, Shuai; Ding, Hailin; Hu, Hai; Pan, Yuanwang; Weerasekara, Vajira; Jiang, Baishan; Wang, Eric S.; Ahearn, Ian; Philips, Mark; Papagiannakopoulos, Thales; Tsirigos, Aristotelis; Rothenberg, Eli; Gainor, Justin; Freeman, Gordon J.; Rudin, Charles M.; Gray, Nathanael S.; Hammerman, Peter S.; Pagano, Michele; Heymach, John V.; Perou, Charles M.; Bardeesy, Nabeel; Wong, Kwok-Kin

研究方向

暂未获取到该数据
C
Charles M. Rudin
H 指数:132论文数:1,694被引数:8.6万
E
Elisa de Stanchina
H 指数:94论文数:1,296被引数:3.9万
E
Eric E. Gardner
H 指数:19论文数:154被引数:3,289
B
Benjamin H. Lok
H 指数:27论文数:256被引数:3,636
J
Jason S. Lewis
H 指数:101论文数:1,161被引数:3.3万
T
Thales Papagiannakopoulos
H 指数:46论文数:228被引数:1.2万
L
Linde A. Miles
H 指数:17论文数:96被引数:3,212
K
Kwok‐Kin Wong
H 指数:140论文数:1,660被引数:7.2万
V
Viola Allaj
H 指数:16论文数:73被引数:3,395
T
Triparna Sen
H 指数:38论文数:317被引数:7,328