胡红｜Hu, Hong

kunming institute of botany, cas副教授

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个人简介

"胡红，成都中医药大学副教授、硕士生导师，教育部长江学者奖励计划通讯评审专家。博士毕业于中国科学院上海生物化学与细胞生物学研究所，主要从事药理学及神经退行性疾病的发病机制研究。入选国家“博士后创新人才支持计划”和四川省“千人计划”青年人才，荣获“中国科学院优秀毕业生”和“北京市优秀毕业生”等荣誉。主持国家自然科学基金青年项目、中国博士后科学基金、四川省自然科学基金等课题。担任全国中医药高等教育“十五五”规划教材《药理学》编委。以第一或通讯作者身份在Cell Death & Differentiation、Nature Communications、Phytotherapy Research、International Immunopharmacology等国际期刊上发表SCI论文，并申请发明专利3项。\n联系方式：huhongdcjz@163.com，欢迎你的加入！\n发表论文\n1 Li Y#, Cheng Q,# Tian S, Li X, Chen Y, Guo Y, Jiang Y, Tao Y, Niu X, Hu H*, Liu Y*, Li SH*. Oridonin ameliorates Alzheimer's disease-like pathology in male mice through inhibition of Receptor-Interacting Protein Kinase 1. Phytotherapy Research, 2026, doi: 10.1002/ptr.70185\n2 Hu H#, Cheng Q#, Li D#, Li Y, Li X, Chen Y, Guo Y, Tian S, Jiang Y, Chen Y, Liu Y, Li SH. Ponicidin ameliorates Alzheimer's disease through dual inhibition of RIPK1-mediated neuroinflammation and necroptosis. International Immunopharmacology, 2026 :171: 116095.\n3 Chen Y, Liu Y, Hu H*, Li SH*. The mtDNA-ZBP1 axis in alzheimer's disease: Mechanisms, pathogenesis, and therapeutic implications. International Immunopharmacology, 2026, 168:115853.\n4 Tian S, Liu Y, Hu H*, Li SH*. Tau Liquid-Liquid Phase Separation in Alzheimer's Disease: Mechanisms, Pathogenesis, and Therapeutic Implications. Molecular Neurobiology, 2025, 63:18.\n5 Li X, Liu Y, Hu H*, Li SH*. Targeting Liquid-Liquid Phase Separation and Autophagy in Alzheimer's Disease: Insights into Molecular Mechanisms and Therapeutic Potential. Neurochemical Research, 2025, 51:9.\n6 Hu H#, Wu XL#, Wu GX, Nan N, Zhang J, Zhu XX, Zhang Y, Shu ZQ, Liu J, Liu XY, Lu JX*, Wang HY*. RIP3-mediated necroptosis is regulated by inter-filament assembly of RIP homotypic interaction motif. Cell Death & Differentiation, 2021, 28: 251-266.\n7 Wu XL#, Hu H#, Dong XQ, Zhang J, Wang J, Schwieters CD, Liu J, Wu GX, Li B, Lin JY, Wang HY*, Lu JX*. The amyloid structure of mouse RIPK3 (receptor interacting protein kinase 3) in cell necroptosis. Nature Communications, 2021, 12: 1627-1640.\n8 Hu H*, Wu GX, Shu ZQ, Yu DD, Nan N, Yuan FY, Liu XY, Wang HY*. ICP6 Prevents RIP1 Activation to Hinder Necroptosis Signaling. Front Cell Dev Biol, 2020, 8: 1257-1265.\n9 Wu XL, Ma YY, Zhao K, Zhang J, Sun YP, Li YC, Dong XQ, Hu H, Liu J, Wang J, Zhang X, Li B, Wang HY, Li D, Sun B, Lu JX*, Liu C*. The structure of a minimum amyloid fibril core formed by necroptosis-mediating RHIM of human RIP3. PNAS, 2021, 118: e2022933118-e2022933218.\n10 Xia BQ, Sui F, Chen XQ, Hu H, Chen PY, Wang HY*, Gao ZB*. MLKL forms cation channels. Cell Research, 2016, 26: 517-528.\n11 Zhang J, Yang Y, Zhou SA, He XY, Cao X, Wu CL, Hu H, Qin J, Wei G, Wang HY, Liu SL*, Sun LM*. Membrane bound TNF mediates microtubule-targeting chemotherapeutics-induced cancer cytolysis via juxtacrine inter-cancer-cell death signaling. Cell Death & Differentiation, 2020, 27: 1569-1587.\n12 Zhu XX, Yang N, Yang Y, Yuan FY, Yu DD, Zhang Y, Shu ZQ, Nan N, Hu H, Liu XY, Chen S, Sun LM* and Wang HY*. Spontaneous necroptosis and autoinflammation are blocked by an inhibitory phosphorylation on MLKL during neonatal development. Cell Research, 2021, 32: 407-410.\n13 Guo K, Zhou TT, Ren X, Li D, Hu H, Liu YC, Liu Y, Li SH*. Secoiridoids and triterpenoids from the traditional Tibetan medicine Gentiana veitchiorum and their immunosuppressive activity. Phytochemistry, 2021, 192: 112961-112966.\n14 Guo K, Ren X, Mu RF, Zhou TT, Li D, Hu H, Liu Y, Li SH*. Ecdysteroids and spirosterane steroids from the traditional Chinese medicine Paris polyphylla var. yunnanensis. Phytochemistry Letters, 2021, 45: 117-120.\n15 Liu J, Yan Q, Wang LX, He XP, Hu H, Liu YC, Li D, Liu Y, Guo K, Li SH, Secoiridoids from the traditional Chinese medicine Swertia pseudochinensis. Phytochemistry, 2023: 210 113642.\n16 Yuan X, Yan Q, Hu H, He XP, Wang LX, Liu YC, Liu Y, Guo K, Li SH, Bioactive triterpenoids from the traditional Chinese medicine Swertia mileensis. Phytochemistry Letters, 2023, 55: 1-5.\n17 Guo K, Ren X, Zhou TT, Li T, Liu YC, Tao Y, Hu H, Li D, Liu Y, Li SH, Secondary metabolites from the Mongolian medicine Lomatogonium carinthiacum. Fitoterapia 2023, 165: 105402.\n18 Ren X, Yuan X, Jiao SS, He XP, Hu H, Kang JJ, Luo SH, Liu Y, Guo K, Li SH. Clerodane diterpenoids from the Uygur medicine Salvia deserta with immunosuppressive activity. Phytochemistry. 2023, 214:113823.\n19 Ye X, Tao Y, Pu XL, Hu H, Chen J, Tan CL, Tan X, Li SH, Liu Y. The genus Paris: a fascinating resource for medicinal and botanical studies. Horticulture Research, 2024, 12: uhae327.\n20 Yan Q, Chen YG, Yang XW, Wang A, He XP, Tang X, Hu H, Guo K, Xiao ZH, Liu Y, Li SH. Engineering a promiscuous prenyltransferase for selective biosynthesis of an undescribed bioactive cannabinoid analog. Communications biology, 2025, 173: 4.\n21 Pu X, Zhang LY, Zhang JY, Ye X, Lin L, Wu DR, Kang JJ, Hu H, Chen J, Guo K, Chen YG, Tao Y, Li SH, Liu Y. Identification of a bZIP transcription factor PpTGA3 regulating polyphyllin biosynthesis in Paris polyphylla. Industrial Crops and Products, 2025, 225: 120492.\n终审：医技学院科研科管理员"