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C

Claire S. Durrant

University of Edinburgh
H指数:11
被引数:1,279

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Astrocyte Proximity Protects Synapses From Human Amyloid-Beta Induced Degeneration in a Mouse Ex Vivo Model of Early Alzheimer's Disease

星形胶质细胞邻近性保护突触免受人源β-淀粉样蛋白诱导的退化，该保护作用在早期阿尔茨海默病小鼠离体模型中得到证实

European Journal of Neuroscience
IF2.4
2026-04-010
OAAI
Gobbo, Francesco; King, Declan; Tulloch, Jane; Gobbo, Davide; Bonthron, Calum; Meftah, Soraya; Stoddart-Campbelton, Caleb; Tamura, Arisa; Rose, Jamie; Smith, Colin; Durrant, Claire; Spires-Jones, Tara L.
Confirmation of p-tau Ser356’s association with Alzheimer’s disease pathology and lowering in response to WZ4003 treatment in brain slice cultures. Reply to: “Phospho-tau Ser356 is mostly confined to pre-NFT neurons in Alzheimer’s pathology”

确认p-tau Ser356与阿尔茨海默病病理学的关联性，以及其在脑片培养中对WZ4003治疗的反应性降低。回复：“磷酸化tau Ser356在阿尔茨海默病病理学中主要局限于前NFT神经元”。

Acta Neuropathologica
IF9.3
2025-12-110
PRE
Lewis W. Taylor; Elizabeth M. Simzer; Lauren F. P. Young; Kristján Holt; Tara L. Spires-Jones; Claire S. Durrant
Evidence for trans-synaptic propagation of oligomeric tau in human progressive supranuclear palsy

证据表明，在人类进行性核上性麻痹中存在寡聚型tau蛋白的跨突触传播。

Nature Neuroscience
IF20
2025-07-160
OA
Robert I. McGeachan; Lois Keavey; Elizabeth M. Simzer; Ya Yin Chang; Jamie L. Rose; Maxwell P. Spires-Jones; Mollie Gilmore; Kristjan Holt; Soraya Meftah; Natalia Ravingerova; Cristina Scutariu; Lewis W. Taylor; Declan King; Makis Tzioras; Jane Tulloch; Sam A. Booker; Imran Liaquat; Nicole Hindley-Pollock; Bethany Geary; Colin Smith; Paul M. Brennan; Claire S. Durrant; Tara L. Spires-Jones
Divergent actions of physiological and pathological amyloid-β on synapses in live human brain slice cultures

生理性和病理性淀粉样β蛋白在活体人脑片培养中对突触的差异性作用

NATURE COMMUNICATIONS
IF15.7
2025-04-300
OA
McGeachan, Robert I.; Meftah, Soraya; Taylor, Lewis W.; Catterson, James H.; Negro, Danilo; Bonthron, Calum; Holt, Kristjan; Tulloch, Jane; Rose, Jamie L.; Gobbo, Francesco; Chang, Ya Yin; Elliott, Jamie; McLay, Lauren; King, Declan; Liaquat, Imran; Spires-Jones, Tara L.; Booker, Sam A.; Brennan, Paul M.; Durrant, Claire S.
Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer's disease
ACTA NEUROPATHOLOGICA
IF9.3
2024-02-066
OAAI
Colom-Cadena, Marti; Toombs, Jamie; Simzer, Elizabeth; Holt, Kristjan; McGeachan, Robert; Tulloch, Jane; Jackson, Rosemary J.; Catterson, James H.; Spires-Jones, Maxwell P.; Rose, Jamie; Waybright, Lora; Caggiano, Anthony O.; King, Declan; Gobbo, Francesco; Davies, Caitlin; Hooley, Monique; Dunnett, Sophie; Tempelaar, Robert; Meftah, Soraya; Tzioras, Makis; Hamby, Mary E.; Izzo, Nicholas J.; Catalano, Susan M.; Durrant, Claire S.; Smith, Colin; Dando, Owen; Spires-Jones, Tara L.
p-tau Ser356 is associated with Alzheimer's disease pathology and is lowered in brain slice cultures using the NUAK inhibitor WZ4003
ACTA NEUROPATHOLOGICA
IF9.3
2024-01-047
OAAI
Taylor, Lewis W.; Simzer, Elizabeth M.; Pimblett, Claire; Lacey-Solymar, Oscar T. T.; McGeachan, Robert I.; Meftah, Soraya; Rose, Jamie L.; Spires-Jones, Maxwell P.; Holt, Kristjan; Catterson, James H.; Koch, Henner; Liaquat, Imran; Clarke, Jonathan H.; Skidmore, John; Smith, Colin; Booker, Sam A.; Brennan, Paul M.; Spires-Jones, Tara L.; Durrant, Claire S.

研究方向

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T
Tara L. Spires‐Jones
H 指数:79论文数:324被引数:2.4万
S
S. Meftah
H 指数:12论文数:82被引数:1,118
R
Robert I. McGeachan
H 指数:10论文数:35被引数:934
J
James H. Catterson
H 指数:11论文数:22被引数:621
K
Kristján Holt
H 指数:7论文数:19被引数:343
S
Sam A. Booker
H 指数:22论文数:78被引数:1,534
L
Lewis W. Taylor
H 指数:6论文数:14被引数:130
J
Jamie Rose
H 指数:18论文数:55被引数:2,575
J
Jane Tulloch
H 指数:15论文数:47被引数:1,522
E
Elizabeth Simzer
H 指数:7论文数:11被引数:309