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F

Felix Y. Feng

University of California San Francisco
H指数:109
被引数:5.0万

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Genome-scale CRISPR screens identify PTGES3 as a direct modulator of androgen receptor function in advanced prostate cancer

基因组规模CRISPR筛选确定PTGES3为晚期前列腺癌雄激素受体功能的直接调节因子

Nature Genetics
IF29
2025-11-050
OAAI
Haolong Li; James E. Melnyk; Becky Xu Hua Fu; Raunak Shrestha; Meng Zhang; Martin Sjöström; Siyu Feng; Jasmine A. Anderson; Wanting Han; Lisa N. Chesner; Hyun Jin Shin; Tatyanah Farsh; Humberto J. Suarez; Seema Nath; Jonathan Chou; Rajdeep Das; Emily A. Egusa; Marsha Calvert; Audrey Kishishita; Abhilash Barpanda; Jun Zhu; Ashutosh Maheshwari; William S. Chen; Mohammed Alshalalfa; Aidan Winters; Junjie T. Hua; Tianyi Liu; Elai Davicioni; Arun P. Wiita; Bradley A. Stohr; Javed Siddiqui; Bo Huang; Eric J. Small; Kevan M. Shokat; Peter S. Nelson; David A. Quigley; Elizabeth V. Wasmuth; Luke A. Gilbert; Felix Y. Feng
Analysis of cfDNA fragmentomics metrics and commercial targeted sequencing panels

cfDNA片段组学指标分析与商业靶向测序面板

Nature Communications
IF15.7
2025-10-140
OAAI
Kyle T. Helzer; Marina N. Sharifi; Jamie M. Sperger; Matthew R. Chrostek; Matthew L. Bootsma; Shannon R. Reese; Amy Taylor; Katie R. Kaufmann; Hannah Krause; Jennifer Schehr; Nan Sethakorn; David Kosoff; Christos E. Kyriakopoulos; Michael Bassetti; Grace Blitzer; John Floberg; Martin Sjöström; Andrew J. Armstrong; Himisha Beltran; Rana R. McKay; Felix Y. Feng; Ruth O’Regan; Kari B. Wisinski; Hamid Emamekhoo; Alex W. Wyatt; Joshua M. Lang; Shuang G. Zhao
Modulating the PPARγ pathway upregulates NECTIN4 and enhances chimeric antigen receptor (CAR) T cell therapy in bladder cancer

通过调节PPARγ通路上调NECTIN4，并增强膀胱癌中嵌合抗原受体（CAR）T细胞疗法。Nat. Commun. 16 (1), 8215

Nature Communications
IF15.7
2025-09-100
OAAI
Kevin Chang; Henry M. Delavan; Elizabeth Yip; Corynn Kasap; Jun Zhu; Roshan Lodha; Sheng-You Liao; Sarah C. Berman; Alberto Carretero-Gonzalez; Merve Basar; Gamze Gokturk Ozcan; Min Yuen Teo; David B. Solit; Jonathan E. Rosenberg; Hikmat Al-Ahmadie; Cornelia C. K. Ding; Emily Chan; Veronica Steri; Sima P. Porten; Vadim S. Koshkin; Terence W. Friedlander; Felix Y. Feng; John K. Lee; Arun P. Wiita; Carissa E. Chu; Jonathan Chou
Tumor transcriptome-wide expression classifiers predict treatment sensitivity in advanced prostate cancers

肿瘤转录组范围表达分类器预测晚期前列腺癌的治疗敏感性

Cell
IF42.5
2025-08-260
OAAI
Emily Grist; Peter Dutey-Magni; Marina A. Parry; Larissa Mendes; Ashwin Sachdeva; James A. Proudfoot; Anis A. Hamid; Mazlina Ismail; Sarah Howlett; Stefanie Friedrich; Lia DePaula Oliveira; Laura Murphy; Christopher Brawley; Oluwademilade Dairo; Sharanpreet Lall; Yang Liu; Daniel Wetterskog; Anna Wingate; Karolina Nowakowska; Leila Zakka; Claire L. Amos; Nafisah B. Atako; Victoria Wang; Hannah L. Rush; Robert J. Jones; Hing Leung; William R. Cross; Silke Gillessen; Chris C. Parker; Teresa Marafioti; Alfonso Urbanucci; Matthew Fittall; Edward M. Schaeffer; Daniel E. Spratt; David Waugh; Thomas Powles; Matthew R. Sydes; Felix Y. Feng; Daniel M. Berney; Mahesh K.B. Parmar; Noel W. Clarke; Elai Davicioni; Tamara L. Lotan; Christopher J. Sweeney; Louise C. Brown; Nicholas D. James; Gerhardt Attard
Leveraging sequences missing from the human genome to diagnose cancer

利用缺失于人类基因组中的序列来诊断癌症

Communications Medicine
IF6.3
2025-08-210
OA
Ilias Georgakopoulos-Soares; Ofer Yizhar-Barnea; Ioannis Mouratidis; Candace S. Y. Chan; Michail Patsakis; Akshatha Nayak; Rachael Bradley; Mayank Mahajan; Jasmine Sims; Dianne Laboy Cintron; Ryder Easterlin; Julia S. Kim; Emmalyn Chen; Geovanni Pineda; Guillermo E. Parada; John S. Witte; Christopher A. Maher; Felix Feng; Ioannis Vathiotis; Nikolaos Syrigos; Emmanouil Panagiotou; Andriani Charpidou; Konstantinos Syrigos; Jocelyn Chapman; Mark Kvale; Martin Hemberg; Nadav Ahituv
Long term results of NRG Oncology RTOG 9601, a randomized trial of radiation with or without anti-androgens (AAT) in patients receiving salvage prostate bed radiation therapy post prostatectomy

NRG Oncology RTOG 9601试验的长期结果，该试验是一项随机试验，研究在前列腺切除术后接受挽救性前列腺床放射治疗的患者中，使用或不使用抗雄激素药物（AAT）的放射治疗效果。

international journal of radiation oncology biology physics
IF0
2025-08-050
PRE
Himanshu R. Lukka; Stephanie L. Pugh; William U. Shipley; Pierre P. Major; Oliver Sartor; Ian S. Dayes; Jean-Paul Bahary; Jason A. Efstathiou; Thomas M. Pisansky; Kenneth L. Zeitzer; Colleen A.F. Lawton; Robert T. Dess; Andrew S. Camarata; Alexander G. Balogh; Luis Souhami; Seth A. Rosenthal; J. Daniel Pennington; Wendy F. Seiferheld; Felix Y. Feng; Howard M. Sandler
Transcriptomic Analysis of Localized High-risk Prostate Cancer Improves Prognostication and Identifies Benefit from Adding Docetaxel to Definitive Radiotherapy with Androgen Suppression in the NRG Oncology/RTOG 0521 Phase 3 Trial

局部高危前列腺癌的转录组学分析改善了预后判断，并确定了在NRG肿瘤学/RTOG 0521 III期试验中，将多西他赛添加到根治性放疗联合雄激素抑制治疗中获益。

European Urology Oncology
IF9.3
2025-07-170
OAAI
Ryan M. Phillips; James A. Proudfoot; Elai Davicioni; Yang Liu; Daniel E. Spratt; Jeff M. Simko; Robert B. Den; Alan Pollack; Seth A. Rosenthal; A. Oliver Sartor; Christopher J. Sweeney; Gerhardt Attard; Leslie Longoria; Samir Patel; Michael W. Straza; Jason A. Efstathiou; Amit B. Shah; Karen E. Hoffman; Joseph P. Rodgers; Howard M. Sandler; Felix Y. Feng; Phuoc T. Tran
Transcriptional profiling clarifies a program of enzalutamide extreme non-response in lethal prostate cancer

转录谱阐明了致死性前列腺癌中恩扎鲁他胺极端无反应的程序

npj Precision Oncology
IF8
2025-07-070
OAAI
Anbarasu Kumaraswamy; Ya-Mei Hu; Joel A. Yates; Chao Zhang; Eva Rodansky; Dhruv Khokhani; Diana Flores; Zhi Duan; Yi Zhang; Shaadi Tabatabaei; Rachel Slottke; Shangyuan Ye; Primo Lara; Adam Foye; Charles J. Ryan; David A. Quigley; Jiaoti Huang; Rahul Aggarwal; Robert E. Reiter; Max S. Wicha; Tomasz M. Beer; Matthew Rettig; Martin Gleave; Christopher P. Evans; Owen N. Witte; Joshua M. Stuart; George V. Thomas; Felix Y. Feng; Eric J. Small; Zheng Xia; Joshi J. Alumkal
Impact of Gene Expression Classifier Testing on Adjuvant Treatment Following Radical Prostatectomy: The G-MINOR Prospective Randomized Cluster-crossover Trial

根治性前列腺切除术后的辅助治疗中基因表达分类器检测的影响：G-MINOR前瞻性随机集群交叉试验

EUROPEAN UROLOGY
IF25.2
2025-02-011
PRE
Morgan, Todd M.; Daignault-Newton, Stephanie; Spratt, Daniel E.; Dunn, Rodney L.; Singhal, Udit; Okoth, Linda A.; Feng, Felix Y.; Johnson, Anna M.; Lane, Brian R.; Linsell, Susan; Ghani, Khurshid R.; Montie, James E.; Mehra, Rohit; Hollenbeck, Brent K.; Maatman, Thomas; Wojno, Kirk; Burks, Frank N.; Bekong, Daniel; Curry, Jon; Rodriguez, Paul; Kleer, Eduardo; Sarle, Richard; Miller, David C.; Cher, Michael L.
Validation of an artificial intelligence-based prognostic biomarker in patients with oligometastatic Castration-Sensitive prostate cancer
RADIOTHERAPY AND ONCOLOGY
IF5.3
2025-01-010
PRE
Wang, Jarey H.; Deek, Matthew P.; Mendes, Adrianna A.; Song, Yang; Shetty, Amol; Bazyar, Soha; van der Eecken, Kim; Chen, Emmalyn; Showalter, Timothy N.; Royce, Trevor J.; Todorovic, Tamara; Huang, Huei-Chung; Houck, Scott A.; Yamashita, Rikiya; Kiess, Ana P.; Song, Daniel Y.; Lotan, Tamara; DeWeese, Theodore; Marchionni, Luigi; Ren, Lei; Sawant, Amit; Simone, Nicole; Berlin, Alejandro; Onal, Cem; Esteva, Andre; Feng, Felix Y.; Tran, Phuoc T.; Sutera, Philip; Ost, Piet
Canonical androgen response element motifs are tumor suppressive regulatory elements in the prostate

规范雄激素反应元件基序是前列腺中的肿瘤抑制调节元件

NATURE COMMUNICATIONS
IF15.7
2024-12-130
OAAI
Chen, Xuanrong; Augello, Michael A.; Liu, Deli; Lin, Kevin; Hakansson, Alex; Sjostrom, Martin; Khani, Francesca; Deonarine, Lesa D.; Liu, Yang; Travascio-Green, Jaida; Wu, Jiansheng; Chan, Un In; Owiredu, Jude; Loda, Massimo; Feng, Felix Y.; Robinson, Brian D.; Davicioni, Elai; Sboner, Andrea; Barbieri, Christopher E.
Genomic classifier performance in intermediate-risk prostate cancer: results from NRG Oncology/RTOG 0126 randomized phase 3 trial (vol 117, pg 370, 2023)
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
IF6.5
2024-12-010
PRE
Spratt, D. E.; Liu, V. Y. T.; Michalski, J.; Davicioni, E.; Berlin, A.; Simko, J. P.; Efstathiou, J. A.; Tran, P. T.; Sandler, H. M.; Hall, W. A.; Thompson, D. J. S.; Parliament, M. B.; Dayes, I. S.; Correa, R. J. M.; Robertson, J. M.; Gore, E. M.; Doncals, D. E.; Vigneault, E.; Souhami, L.; Karrison, T. G.; Feng, F. Y.
Meta-analysis of Individual Patient-level Data for a Multimodal Artificial Intelligence Biomarker in High-risk Prostate Cancer: Results from Six NRG/RTOG Phase 3 Randomized Trials

高风险前列腺癌中多模式人工智能生物标志物的个体患者水平数据的荟萃分析: 来自六项NRG/RTOG 3期随机试验的结果

EUROPEAN UROLOGY
IF25.2
2024-10-010
OA
Spratt, Daniel E.; Liu, Vinnie Y. T.; Jia, Angela Y.; Royce, Trevor J.; Sandler, Howard M.; Pugh, Stephanie L.; Tran, Phuoc T.; Feng, Felix Y.
CDK12 loss drives prostate cancer progression, transcription-replication conflicts, and synthetic lethality with paralog CDK13
CELL REPORTS MEDICINE
IF10.6
2024-10-010
OAAI
Tien, Jean Ching-Yi; Luo, Jie; Chang, Yu; Zhang, Yuping; Cheng, Yunhui; Wang, Xiaoju; Yang, Jianzhang; Mannan, Rahul; Mahapatra, Somnath; Shah, Palak; Wang, Xiao-Ming; Todd, Abigail J.; Eyunni, Sanjana; Cheng, Caleb; Rebernick, Ryan J.; Xiao, Lanbo; Bao, Yi; Neiswender, James; Brough, Rachel; Pettitt, Stephen J.; Cao, Xuhong; Miner, Stephanie J.; Zhou, Licheng; Wu, Yi-Mi; Labanca, Estefania; Wang, Yuzhuo; Parolia, Abhijit; Cieslik, Marcin; Robinson, Dan R.; Wang, Zhen; Feng, Felix Y.; Chou, Jonathan; Lord, Christopher J.; Ding, Ke; Chinnaiyan, Arul M.
External Validation of a Digital Pathology-based Multimodal Artificial Intelligence Architecture in the NRG/RTOG 9902 Phase 3 Trial

NRG/RTOG 9902 3期试验中基于数字病理学的多模态人工智能架构的外部验证

EUROPEAN UROLOGY ONCOLOGY
IF9.3
2024-10-012
OA
Ross, Ashley E.; Zhang, Jingbin; Huang, Huei-Chung; Yamashita, Rikiya; Keim-Malpass, Jessica; Simko, Jeffry P.; Devries, Sandy; Morgan, Todd M.; Souhami, Luis; Dobelbower, Michael C.; Mcginnis, L. Scott; Jones, Christopher U.; Dess, Robert T.; Zeitzer, Kenneth L.; Choi, Kwang; Hartford, Alan C.; Michalski, Jeff M.; Raben, Adam; Gomella, Leonard G.; Sartor, A. Oliver; Rosenthal, Seth A.; Sandler, Howard M.; Spratt, Daniel E.; Pugh, Stephanie L.; Mohamad, Osama; Esteva, Andre; Chen, Emmalyn; Schaeffer, Edward M.; Tran, Phuoc T.; Feng, Felix Y.
Clinical cell-surface targets in metastatic and primary solid cancers
JCI INSIGHT
IF6.1
2024-09-240
OA
Sharifi, Marina N.; Shi, Yue; Chrostek, Matthew R.; Callahan, S. Carson; Shang, Tianfu; Berg, Tracy J.; Helzer, Kyle T.; Bootsma, Matthew L.; Sjostrom, Martin; Josefsson, Andreas; Feng, Felix Y.; Huffman, Laura B.; Schulte, Chris; Blitzer, Grace C.; Sodji, Quaovi H.; Morris, Zachary S.; Ma, Vincent T.; Meimetis, Labros; Kosoff, David; Taylor, Amy K.; LeBeau, Aaron M.; Lang, Joshua M.; Zhao, Shuang G.

研究方向

暂未获取到该数据
D
Daniel E. Spratt
H 指数:76论文数:977被引数:2.4万
E
Elai Davicioni
H 指数:76论文数:982被引数:1.8万
S
Shuang G. Zhao
H 指数:51论文数:412被引数:1.1万
P
Paul L. Nguyen
H 指数:83论文数:936被引数:2.8万
H
Howard M. Sandler
H 指数:104论文数:941被引数:4.8万
A
Arul M. Chinnaiyan
H 指数:144论文数:1,700被引数:9.7万
T
Todd M. Morgan
H 指数:71论文数:755被引数:1.9万
E
Eric J. Small
H 指数:118论文数:1,322被引数:6.8万
S
Scott A. Tomlins
H 指数:102论文数:938被引数:5.2万
R
Robert B. Den
H 指数:55论文数:506被引数:1.0万