Cristina Aguayo‐Mazzucato

harvard medical school

25H指数

63论文数

3.5K被引数

收录论文 35

发表时间

Small RNA profiling reveals inflammatory and mitochondrial changes in aging β cells and islet macrophages 小RNA分析揭示了衰老β细胞和胰岛巨噬细胞的炎症及线粒体变化

Communications Biology

IF5.1

2026-09-30

OAAI

Claudiane Guay; Jérôme Perrard; Eleonora Mangano; Véronique Menoud; Alessandra Galli; Francesco Alabiso; Elena Aiello; Daniela Fignani; Francesco Dotta; Susan Bonner-Weir; Guido Sebastiani; Cristina Aguayo-Mazzucato; Cristina Cosentino; Romano Regazzi

iCLAP: an innovative method for integrable co-detection of low-abundance antigens with high-plex immunostaining iCLAP：一种用于低丰度抗原可积联检与高通量免疫染色的创新方法

Nature Communications

IF15.7

2026-02-24

OAAI

Fan Wu; Shuyuan Zheng; Yani Chen; Peijia Ye; Moo Joong Kim; Seojin Lee; Geroge Kuo; Shriya Pillan; Ruihan Yuan; Kyu Sang Han; Bofei Yu; Qingfeng Zhu; Sarah M. Shin; Courtney D. Cannon; Gabriele Pierre; Kanako Iwasaki; Cristina Aguayo-Mazzucato; Nicolas Musi; George A. Kuchel; Birgit Schilling; Laura D. Wood; Won Jin Ho; Robert A. Anders; Denis Wirtz; Pei-Hsun Wu

Advancing biological understanding of cellular senescence with computational multiomics 通过计算多组学推进对细胞衰老的生物学理解

Nature Genetics

IF0

2025-09-15

PREAI

Sheng Li; Paula A. Agudelo Garcia; Constantin Aliferis; Michael J. Becich; Jazmin Calyeca; Benjamin D. Cosgrove; Jennifer Elisseeff; Negin Farzad; Elana J. Fertig; Carolyn Glass; Liangcai Gu; Qianjiang Hu; Zhicheng Ji; Melanie Königshoff; Nathan K. LeBrasseur; Dongmei Li; Anjun Ma; Qin Ma; Vilas Menon; Jacob T. Mitchell; Ana L. Mora; Sushma Nagaraj; Andrew C. Nelson; Laura J. Niedernhofer; Mauricio Rojas; Hash Brown Taha; Jinhua Wang; Siyuan Wang; Pei-Hsun Wu; Jichun Xie; Ming Xu; Miao Yu; Xu Zhang; Yue Zhao; Peter D. Adams; Cristina Aguayo-Mazzucato; Darren J. Baker; Christopher Benz; David A. Bernlohr; Marta Bueno; Jin Chen; Bennett G. Childs; Jeffrey H. Chuang; Dongjun Chung; Mythili Dileepan; Li Ding; Mingze Dong; Francesca Duncan; Archibald Enninful; William F. Flynn; Ana Catarina Franco; David Furman; Vesna Garovic; Stephanie Halene; Allison B. Herman; Ann V. Hertzel; Kanako Iwasaki; Hyeongseon Jeon; Jeon Woong Kang; Shilpita Karmakar; James L. Kirkland; Ron Korstanje; Erich Kummerfeld; Jun Hee Lee; Yang Liu; Yao Lu; Jose Lugo-Martinez; Helene Martini; Simon Melov; Nicolas Musi; João F. Passos; Samuel T. Peters; Irfan Rahman; Ramalakshmi Ramasamy; Alexandra N. Rindone; Paul D. Robbins; Paul Robson; Jhonny Rodriguez-Lopez; Lorena Rosas; Nadia Rosenthal; Marissa J. Schafer; Birgit Schilling; Elizabeth L. Schmidt; Kevin Schneider; Kaustav Sengupta; Jian Shu; Peter T. C. So; Li Sun; Tamar Tchkonia; Marcos G. Teneche; Natalia Vanegas; Julia Wang; Juan Xie; Shanshan Yin; Ke Zhang; Quan Zhu; Rong Fan

Exercise activates AMPK in mouse and human pancreatic islets to decrease senescence 运动激活小鼠和人胰岛中的AMPK以减少衰老

NATURE METABOLISM

IF20.8

2024-09-24

PREAI

Carapeto, Priscila; Iwasaki, Kanako; Hela, Francesko; Kahng, Jiho; Alves-Wagner, Ana B.; Middelbeek, Roeland J. W.; Hirshman, Michael F.; Rutter, Guy A.; Goodyear, Laurie J.; Aguayo-Mazzucato, Cristina

SenNet recommendations for detecting senescent cells in different tissues SenNet建议检测不同组织中的衰老细胞

NATURE REVIEWS MOLECULAR CELL BIOLOGY

IF90.2

2024-06-03

PREAI

Suryadevara, Vidyani; Hudgins, Adam D.; Rajesh, Adarsh; Pappalardo, Alberto; Karpova, Alla; Dey, Amit K.; Hertzel, Ann; Agudelo, Anthony; Rocha, Azucena; Soygur, Bikem; Schilling, Birgit; Carver, Chase M.; Aguayo-Mazzucato, Cristina; Baker, Darren J.; Bernlohr, David A.; Jurk, Diana; Mangarova, Dilyana B.; Quardokus, Ellen M.; Enninga, Elizabeth Ann L.; Schmidt, Elizabeth L.; Chen, Feng; Duncan, Francesca E.; Cambuli, Francesco; Kaur, Gagandeep; Kuchel, George A.; Lee, Gung; Daldrup-Link, Heike E.; Martini, Helene; Phatnani, Hemali; Al-Naggar, Iman M.; Rahman, Irfan; Nie, Jia; Passos, Joao F.; Silverstein, Jonathan C.; Campisi, Judith; Wang, Julia; Iwasaki, Kanako; Barbosa, Karina; Metis, Kay; Nernekli, Kerem; Niedernhofer, Laura J.; Ding, Li; Wang, Lichao; Adams, Lisa C.; Ruiyang, Liu; Doolittle, Madison L.; Teneche, Marcos G.; Schafer, Marissa J.; Xu, Ming; Hajipour, Mohammadjavad; Boroumand, Mozhgan; Basisty, Nathan; Sloan, Nicholas; Slavov, Nikolai; Kuksenko, Olena; Robson, Paul; Gomez, Paul T.; Vasilikos, Periklis; Adams, Peter D.; Carapeto, Priscila; Zhu, Quan; Ramasamy, Ramalakshmi; Perez-Lorenzo, Rolando; Fan, Rong; Dong, Runze; Montgomery, Ruth R.; Shaikh, Sadiya; Vickovic, Sanja; Yin, Shanshan; Kang, Shoukai; Suvakov, Sonja; Khosla, Sundeep; Garovic, Vesna D.; Menon, Vilas; Xu, Yanxin; Song, Yizhe; Suh, Yousin; Dou, Zhixun; Neretti, Nicola

Cellular senescence in diabetes: from markers to mechanisms and therapies

FRONTIERS IN ENDOCRINOLOGY

IF4.6

2023-12-18

OAAI

Aguayo-Mazzucato, Cristina; Cha, Jeeyeon; Thompson, Peter J.

Heterogeneity of increased biological age in type 2 diabetes correlates with differential tissue DNA methylation, biological variables, and pharmacological treatments

GEROSCIENCE

IF5.4

2023-11-21

OAAI

Cortez, Briana N.; Pan, Hui; Hinthorn, Samuel; Sun, Han; Neretti, Nicola; Gloyn, Anna L.; Aguayo-Mazzucato, Cristina

Interaction between Autophagy and Senescence in Pancreatic Beta Cells 自噬与胰岛 β 细胞衰老的相互作用

BIOLOGY-BASEL

IF3.5

2023-09-04

OAAI

Hela, Francesko; Aguayo-Mazzucato, Cristina

Pancreatic β-cell senescence in diabetes: mechanisms, markers and therapies 糖尿病胰岛 β 细胞衰老: 机制、标志物和治疗

FRONTIERS IN ENDOCRINOLOGY

IF4.6

2023-08-31

OAAI

Cha, Jeeyeon; Aguayo-Mazzucato, Cristina; Thompson, Peter J.

Regulation of Cellular Senescence in Type 2 Diabetes Mellitus: From Mechanisms to Clinical Applications 2型糖尿病细胞衰老的调控: 从机制到临床应用

DIABETES & METABOLISM JOURNAL

IF8.5

2023-07-31

OAAI

Iwasaki, Kanako; Abarca, Cristian; Aguayo-Mazzucato, Cristina

Decreased IGF1R attenuates senescence and improves function in pancreatic β-cells

FRONTIERS IN ENDOCRINOLOGY

IF4.6

2023-06-27

OAAI

Iwasaki, Kanako; Lalani, Benjamin; Kahng, Jiho; Carapeto, Priscila; Sanjines, Stephanie; Hela, Francesko; Abarca, Cristian; Tsuji, Tadataka; Darcy, Justin; Bartke, Andrzej; Tseng, Yu-Hua; Kulkarni, Rohit N. N.; Aguayo-Mazzucato, Cristina

FunDNAmethyl Mechanism for Developmental Restriction of a β-Cell Subpopulation

DIABETES

IF7.5

2023-04-20

OAAI

Aguayo-Mazzucato, Cristina; Stitzel, Michael L.

NIH SenNet Consortium to map senescent cells throughout the human lifespan to understand physiological health NIH SenNet联盟绘制人类整个生命周期中的衰老细胞以了解生理健康

NATURE AGING

IF19.4

2022-12-20

OAAI

Lee, Patty J.; Benz, Christopher C.; Blood, Philip; Boerner, Katy; Campisi, Judith; Chen, Feng; Daldrup-Link, Heike; De Jager, Phil; Ding, Li; Duncan, Francesca E.; Eickelberg, Oliver; Fan, Rong; Finkel, Toren; Furman, David; Garovic, Vesna; Gehlenborg, Nils; Glass, Carolyn; Heckenbach, Indra; Joseph, Ziv-Bar; Katiyar, Pragati; Kim, So-Jin; Koenigshoff, Melanie; Kuchel, George A.; Lee, Haesung; Lee, Jun Hee; Ma, Jian; Ma, Qin; Melov, Simon; Metis, Kay; Mora, Ana L.; Musi, Nicolas; Neretti, Nicola; Passos, Joao F.; Rahman, Irfan; Rivera-Mulia, Juan Carlos; Robson, Paul; Rojas, Mauricio; Roy, Ananda L.; Scheibye-Knudsen, Morten; Schilling, Birgit; Shi, Pixu; Silverstein, Jonathan C.; Suryadevara, Vidyani; Xie, Jichun; Wang, Jinhua; Wong, A. Ian; Niedernhofer, Laura J.; Wang, Siyuan (Steven); Anvari, Hannah; Balough, Julia; Benz, Christopher; Bons, Joanna; Brenerman, Boris; Evans, William; Gerencser, Akos; Gregory, Heather; Hansen, Malene; Justice, Jamie; Kapahi, Pankaj; Murad, Natalia; O'Broin, Amy; Pavone, Mary Ellen; Powell, Mark; Scott, Gary; Shanes, Elisheva; Shankaran, Mahalakshmi; Verdin, Eric; Winer, Daniel; Wu, Fei; Adams, Andrew; Blood, Philip D.; Bueckle, Andreas; Cao-Berg, Ivan; Chen, Hao; Davis, Michael; Filus, Shane; Hao, Yuhan; Hartman, Austin; Hasanaj, Euxhen; Helfer, Jesse; Herr, Bruce, II; Bar Joseph, Ziv; Molla, Gesmira; Mou, Gloria; Puerto, Juan; Quardokus, Ellen M.; Ropelewski, Alexander J.; Ruffalo, Matt; Satija, Rahul; Schwenk, Melissa; Scibek, Robin; Shirey, William; Sibilla, Max; Welling, Joel; Yuan, Zhou; Bonneau, Richard; Christiano, Angela; Izar, Benjamin; Menon, Vilas; Owens, David M.; Phatnani, Hemali; Smith, Colin; Suh, Yousin; Teich, Andrew F.; Bekker, Valerie; Chan, Cliburn; Coutavas, Elias; Hartwig, Matthew G.; Ji, Zhicheng; Nixon, Andrew B.; Dou, Zhixun; Rajagopal, Jayaraj; Slavov, Nikolai; Holmes, David, III; Jurk, Diana; Kirkland, James L.; Lagnado, Anthony; Tchkonia, Tamara; Abraham, Kristin; Dibattista, Amanda; Fridell, Yih-Woei; Howcroft, T. Kevin; Jhappan, Chamelli; Montes, Viviana Perez; Prabhudas, Mercy; Resat, Haluk; Taylor, Veronica; Kumar, Manoj; Cigarroa, Francisco; Cohn, Rachel; Cortes, Tiffany M.; Courtois, Elise; Chuang, Jeffrey; Dave, Monica; Domanskyi, Sergii; Enninga, Elizabeth Ann Lieser; Eryilmaz, Giray Naim; Espinoza, Sara E.; Gelfond, Jon; Kirkland, James; Kuo, Chia-Ling; Lehman, Julia S.; Aguayo-Mazzucato, Cristina; Meves, Alexander; Rani, Meenakshi; Sanders, Shane; Thibodeau, Asa; Tullius, Stefan G.; Ucar, Duygu; White, Brian; Wu, Qian; Xu, Ming; Yamaguchi, Seiji; Assarzadegan, Naziheh; Cho, Chun-Seok; Hwang, Irene; Hwang, Yongha; Xi, Jingyue; Adeyi, Oyedele A.; Aliferis, Constantin F.; Bartolomucci, Alessandro; Dong, Xiao; DuFresne-To, Mickayla J.; Ikramuddin, Sayeed; Johnson, Steve G.; Nelson, Andrew C.; Revelo, Xavier S.; Trevilla-Garcia, Claudia; Sedivy, John M.; Thompson, Elizabeth L.; Robbins, Paul D.; Wang, Jinhua; Aird, Katherine M.; Alder, Jonathan K.; Beaulieu, Delphine; Bueno, Marta; Calyeca, Jazmin; Chamucero-Millaris, Julian A.; Chan, Stephen Y.; Chung, Dongjun; Corbett, Anthony; Gorbunova, Vera; Gowdy, Kymberly M.; Gurkar, Aditi; Horowitz, Jeffrey C.; Hu, Qianjiang; Kaur, Gagandeep; Khaliullin, Timur O.; Lafyatis, Robert; Lanna, Serafina; Li, Dongmei; Ma, Anjun; Morris, Alison; Muthumalage, Thivanka M.; Peters, Victor; Pryhuber, Gloria S.; Reader, Brenda F.; Rosas, Lorena; Sembrat, John C.; Shaikh, Sadiya; Shi, Hangchuan; Stacey, Sean D.; St Croix, Claudette; Wang, Cankun; Wang, Qixin; Watts, Andrew; Gu, Liangcai; Lin, Yiing; Rabinovitch, Peter S.; Sweetwyne, Mariya T.; Artyomov, Maxim N.; Ballentine, Samuel J.; Chheda, Milan G.; Davies, Sherri R.; DiPersio, John F.; Fields, Ryan C.; Fitzpatrick, James A. J.; Fulton, Robert S.; Imai, Shin-ichiro; Jain, Sanjay; Ju, Tao; Kushnir, Vladimir M.; Link, Daniel C.; Ben Major, Michael; Oh, Stephen T.; Rapp, Daniel; Rettig, Michael P.; Stewart, Shelia A.; Veis, Deborah J.; Vij, Kiran R.; Wendl, Michael C.; Wyczalkowski, Matthew A.; Craft, Joseph E.; Enninful, Archibald; Farzad, Negin; Gershkovich, Peter; Halene, Stephanie; Kluger, Yuval; VanOudenhove, Jennifer; Xu, Mina; Yang, Junchen; Yang, Mingyu

PAHSAs reduce cellular senescence and protect pancreatic beta cells from metabolic stress through regulation of Mdm2/p53 PAHSAs通过调节Mdm2/p53减少细胞衰老并保护胰岛 β 细胞免受代谢应激

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-11-14

OAAI

de Celis, Maria F. Rubin; Garcia-Martin, Ruben; Syed, Ismail; Lee, Jennifer; Aguayo-Mazzucato, Cristina; Bonner-Weir, Susan; Kahn, Barbara B.

Extracellular Nicotinamide Phosphoribosyltransferase Is a Component of the Senescence-Associated Secretory Phenotype

FRONTIERS IN ENDOCRINOLOGY

IF4.6

2022-07-14

OAAI

Kuehnemann, Chisaka; Hu, Kang-Quan; Butera, Kayla; Patel, Sandip K.; Bons, Joanna; Schilling, Birgit; Aguayo-Mazzucato, Cristina; Wiley, Christopher D.

Bromodomain Inhibition Reveals FGF15/19 As a Target of Epigenetic Regulation and Metabolic Control

DIABETES

IF7.5

2022-01-31

OAAI

Kozuka, Chisayo; Efthymiou, Vissarion; Sales, Vicencia M.; Zhou, Liyuan; Osataphan, Soravis; Yuchi, Yixing; Chimene-Weiss, Jeremy; Mulla, Christopher; Isganaitis, Elvira; Desmond, Jessica; Sanechika, Suzuka; Kusuyama, Joji; Goodyear, Laurie; Shi, Xu; Gerszten, Robert E.; Aguayo-Mazzucato, Cristina; Carapeto, Priscila; Teixeira, Silvania DaSilva; Sandoval, Darleen; Alonso-Curbelo, Direna; Wu, Lei; Qi, Jun; Patti, Mary-Elizabeth

Diabetes mellitus correlates with increased biological age as indicated by clinical biomarkers

GEROSCIENCE

IF5.4

2021-11-12

OAAI

Bahour, Nadine; Cortez, Briana; Pan, Hui; Shah, Hetal; Doria, Alessandro; Aguayo-Mazzucato, Cristina

Exercise as a Strategy to Decrease Pancreatic β-Cell Senescence

DIABETES

IF7.5

2021-06-01

PREAI

Carapeto, Priscila; Aguayo-Mazzucato, Cristina