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M

Michael S.Y. Huen

The University of Hong Kong

H指数:39

被引数:5,983

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BRCAness in FLT3-ITD AML confers vulnerability to PARP inhibition

FLT3-ITD急性髓系白血病中的BRCA样表型赋予对PARP抑制剂的敏感性

Cell Death & Disease

IF9.6

2026-10-140

OAAI

SAPCD2 phosphorylation modulates astral microtubule stability to control spindle orientation

SAPCD2磷酸化调控星状微管稳定性以控制纺锤体取向

Communications Biology

IF5.1

2026-05-180

OAAI

The PARP1–EXD2 axis orchestrates R-loop resolution to safeguard genome stability

PARP1–EXD2轴调控R-环的解析以保护基因组稳定性

Nature Chemical Biology

IF13.7

2025-06-270

PRE

PHF8 facilitates transcription recovery following DNA double-strand break repair

NUCLEIC ACIDS RESEARCH

IF13.1

2024-08-011

OAAI

R-loop resolution by ARIP4 helicase promotes androgen-mediated transcription induction

SCIENCE ADVANCES

IF12.5

2024-07-190

OAAI

Nuclear F-actin assembly on damaged chromatin is regulated by DYRK1A and Spir1 phosphorylation

NUCLEIC ACIDS RESEARCH

IF13.1

2024-07-050

OAAI

Synergistic anticancer effect by targeting CDK2 and EGFR-ERK signaling

JOURNAL OF CELL BIOLOGY

IF6.4

2023-11-133

OAAI

Noncanonical E2 variant-independent function of UBC13 in promoting checkpoint protein assembly

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-2750

OAAI

Histone Ubiquitination Associates with BRCA1-Dependent DNA Damage Response

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-21135

OAAI

RNF4 controls the extent of replication fork reversal to preserve genome stability

NUCLEIC ACIDS RESEARCH

IF13.1

2022-05-3012

OAAI

Regulation of Wnt/PCP signaling through p97/VCP-KBTBD7-mediated Vangl ubiquitination and endoplasmic reticulum-associated degradation

SCIENCE ADVANCES

IF12.5

2021-05-1431

OAAI

ATM controls the extent of DNA end resection by eliciting sequential posttranslational modifications of CtIP

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-03-1516

OA

PRMT6 deficiency induces autophagy in hostile microenvironments of hepatocellular carcinoma tumors by regulating BAG5-associated HSC70 stability

IF10.1

2021-03-0122

PREAI

A DYRK1B-dependent pathway suppresses rDNA transcription in response to DNA damage

NUCLEIC ACIDS RESEARCH

IF13.1

2021-01-1913

OAAI

RECQL5 KIX domain splicing isoforms have distinct functions in transcription repression and DNA damage response

RECQL5 KIX结构域剪接同工型在转录抑制和DNA损伤反应中具有不同的功能

IF2.7

2021-01-012

PREAI

The novel male meiosis recombination regulator coordinates the progression of meiosis prophase I

JOURNAL OF GENETICS AND GENOMICS

IF7.1

2020-08-019

OAAI

Screen identifies DYRK1B network as mediator of transcription repression on damaged chromatin

屏幕识别DYRK1B网络作为受损染色质转录抑制的介体

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-07-0122

OAAI

Perfecting DNA double-strand break repair on transcribed chromatin

GUARDIANS OF THE GENOME: DNA DAMAGE AND REPAIR

IF0

2020-04-209

PRE

53BP1 loss rescues embryonic lethality but not genomic instability of BRCA1 total knockout mice

CELL DEATH AND DIFFERENTIATION

IF15.4

2020-03-0530

OAAI

LC8/DYNLL1 is a 53BP1 effector and regulates checkpoint activation

NUCLEIC ACIDS RESEARCH

IF13.1

2019-04-1537

OAAI