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G

GutkindJ.Silvio (J. Silvio Gutkind)

University of California San Diego
H指数:140
被引数:6.6万

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教育背景

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工作经历

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荣誉奖项

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B cell subsets are associated with durable responses in distinct cancer types after immune checkpoint inhibition

B细胞亚群与免疫检查点抑制后不同癌症类型的持久性反应相关

Science Translational Medicine
IF14.6
2026-10-280
PRE
Sangwoo Shawn Kim; Sayuri Miyauchi; Riley N. Jones; Elizabeth Weihe; Lin Zhang; Jamillah Murtadha; Stephen T. Ryan; Shumei Kato; Razelle Kurzrock; Jason K. Sicklick; Ezra E. W. Cohen; Sandip P. Patel; Sarah G. Boles; Kathryn A. Gold; Gregory P. Botta; Hitendra Patel; Rebecca A. Shatsky; Susan M. Kaech; Souvick Roy; P. Dominick Sanders; James D. Murphy; Christopher J. Kane; Emily I. Pittman; Jingjing Zou; Minya Pu; Natalie E. Quach; J. Silvio Gutkind; Karen Messer; Diane Simeone; Loren K. Mell; Joseph A. Califano; Christina Jamieson; Arno J. Mundt; Andrew B. Sharabi
The COX2-PGE2-PKA axis suppresses antiviral immunity by inhibiting mtDNA-dependent STING activation

COX2-PGE<sub>2</sub>-PKA轴通过抑制线粒体DNA依赖的STING激活来抑制抗病毒免疫

Cell Reports
IF6.9
2026-10-160
OAAI
Pham Thuy Tien Vo; Julien Cicero; Zichen Wang; Hiroyuki Hakozaki; Thomas S. Hoang; Sendi Rafael Adame-Garcia; Dana J. Ramms; Kuniaki Sato; Erica Stevenson; Yuan Zhou; Katie Fan; Juliette A. Bokor; Vasiliya Kril; Cara Schiavon; Scott B. Biering; Danielle L. Swaney; Nevan J. Krogan; Johannes Schöneberg; Uri Manor; J. Silvio Gutkind
Interactions of Antibody Drug Conjugate Anti-Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

抗体药物偶联物中的微管蛋白靶向剂和拓扑异构酶I抑制剂有效载荷与放射治疗相互作用以增强免疫治疗

Advanced Science
IF14.1
2025-10-240
OAAI
Jacqueline Lesperance; Bryan S. Yung; Michael M. Allevato; Marcus M Cheng; Maria F. Camargo; Robert Saddawi-Konefka; Kanika Dhawan; Ashwyn K. Sharma; Mahsa Mortaja; Sophie Bice; Daniel J. Scanderbeg; Diego Alvarado; Jyoti Mayadev; Ramez N. Eskander; Stephen R. Adams; Pippa F. Cosper; J. Silvio Gutkind; Sunil J. Advani
Inhibition of anti-apoptotic BCL2 overcomes adaptive resistance to co-targeting of the protein kinase FAK and MEK in GNAQ-driven uveal melanoma

抑制抗凋亡BCL2克服了针对FAK和MEK蛋白激酶联合靶向在GNAQ驱动的眼葡萄膜黑色素瘤中的适应性耐药

Journal of Biological Chemistry
IF3.9
2025-09-110
OAAI
Simone Lubrano; Rodolfo Daniel Cervantes-Villagrana; Nadia Arang; Adam Officer; Sendi Rafael Adame-Garcia; Gabriela Cuesta-Margolles; Andrew E. Aplin; J.Silvio Gutkind
Multistate oral carcinogenesis-A prospective cohort study and a parallel case-control study in Taiwan
ORAL ONCOLOGY
IF3.9
2025-03-010
PRE
Wang, Cheng-Ping; Yu, Kelly J.; Chen, Tseng-Cheng; Tsai, Ming-shui; Kang, Chung-Jan; Chien, Chi-Yen; Engels, Eric A.; Hua, Chun-Hung; Hsu, Wan-Lun; Chang, Yih-Leong; Dawsey, Sanford M.; Wentzensen, Nicolas; Shi, Jianxin; Mao, Fangya; Cheung, Li C.; Katki, Hormuzd A.; Boyd, Eric; Wu, Chen-Tu; Gutkind, J. Silvio; Molinolo, Alfredo; Limbach, Abberly-Lott; Lingen, Mark W.; Lou, Pei-Jen; Chen, Chien-Jen; Hildesheim, Allan; Chaturvedi, Anil K.
Focal adhesion kinase-YAP signaling axis drives drug-tolerant persister cells and residual disease in lung cancer
NATURE COMMUNICATIONS
IF15.7
2024-05-0310
OAAI
Haderk, Franziska; Chou, Yu-Ting; Cech, Lauren; Fernandez-Mendez, Celia; Yu, Johnny; Olivas, Victor; Meraz, Ismail M.; Rabago, Dora Barbosa; Kerr, D. Lucas; Gomez, Carlos; Allegakoen, David V.; Guan, Juan; Shah, Khyati N.; Herrington, Kari A.; Gbenedio, Oghenekevwe M.; Nanjo, Shigeki; Majidi, Mourad; Tamaki, Whitney; Pourmoghadam, Yashar K.; Rotow, Julia K.; McCoach, Caroline E.; Riess, Jonathan W.; Gutkind, J. Silvio; Tang, Tracy T.; Post, Leonard; Huang, Bo; Santisteban, Pilar; Goodarzi, Hani; Bandyopadhyay, Sourav; Kuo, Calvin J.; Roose, Jeroen P.; Wu, Wei; Blakely, Collin M.; Roth, Jack A.; Bivona, Trever G.
The landscape of cancer-rewired GPCR signaling axes
CELL GENOMICS
IF9
2024-05-012
OAAI
Arora, Chakit; Matic, Marin; Bisceglia, Luisa; Di Chiaro, Pierluigi; Rosa, Natalia De Oliveira; Carli, Francesco; Clubb, Lauren; Fard, Lorenzo Amir Nemati; Kargas, Giorgos; Diaferia, Giuseppe R.; Vukotic, Ranka; Licata, Luana; Wu, Guanming; Natoli, Gioacchino; Gutkind, J. Silvio; Raimondi, Francesco

研究方向

蛋白质工程蛋白质结构信号转导G蛋白偶联受体G蛋白
A
Alfredo Molinolo
H 指数:72论文数:527被引数:1.4万
王
王志勇
H 指数:50论文数:302被引数:7,765
V
Vyomesh Patel
H 指数:54论文数:284被引数:1.1万
P
Panomwat Amornphimoltham
H 指数:37论文数:169被引数:4,961
D
Daniel Martı́n
H 指数:46论文数:169被引数:8,019
R
Ramiro Iglesias‐Bartolomé
H 指数:25论文数:66被引数:3,034
H
Hidemi Teramoto
H 指数:26论文数:73被引数:7,340
C
Colleen L. Doçi
H 指数:13论文数:57被引数:912
N
Nadia Arang
H 指数:20论文数:89被引数:1,955
C
Constantinos M. Mikelis
H 指数:32论文数:147被引数:3,714