Miguel C. Seabra - Publications, H-index & Citations

Miguel C. Seabra

Universidade Nova de Lisboa

83H指数

286论文数

2.6W被引数

收录论文 123

发表时间

Enhancing lysosome function via TFEB activation reduces lipofuscin-like granules in the retinal pigment epithelium 通过TFEB激活增强溶酶体功能可减少视网膜色素上皮中的脂褐素样颗粒

Experimental Eye Research

IF2.7

2026-08-24

OAAI

Ana S. Falcão; Mafalda Lopes-da-Silva; Pedro Antas; Cristina Escrevente; Margarida Pedro; Beatriz Felgueiras; Beatriz Caires; Rita Coelho; Inês S. Ferreira; Inês P. Santos; Thomas Ciossek; Paul Nicklin; Sandra Tenreiro; Miguel C. Seabra

NRF2 as a guardian of health: from an ancient survival pathway to a modern therapeutic target NRF2作为健康守护者：从古老的生存通路到现代治疗靶点

Redox Biology

IF11.9

2026-05-15

OAAI

Sandra Tenreiro; Ana Sofia Falcão; Nicole Bender; Iveta Bernatova; Alessandra Berry; Antonio Cuadrado; Patrick Eppenberger; Letizia Giona; Anna Grochot-Przeczek; Elke Heiss; Monika Jakubowska; Paul F. Long; Asya Makhro; Mojgan Masoodi; Christina Morgenstern; Luciano Saso; Miguel C. Seabra; Alicja Sznarkowska; Gerasimos Sykiotis; Ioannis P. Trougakos

Insights into lysosome-related organelle biogenesis: melanosome as a model organelle

Frontiers in Cell and Developmental Biology

IF4.3

2026-01-17

OAAI

Duarte C. Barral†‡; Cédric Delevoye†‡; Lionel Larue†‡; Miguel C. Seabra†‡; Graça Raposo†‡; Subba Rao Gangi Setty†‡

Daily Light Onset and Plasma Membrane Tethers Regulate Mitochondria Redistribution within the Retinal Pigment Epithelium

CELLS

IF5.2

2024-06-25

OAAI

Neto, Matilde V.; De Rossi, Giulia; Berkowitz, Bruce A.; Seabra, Miguel C.; Luthert, Philip J.; Futter, Clare E.; Burgoyne, Thomas

Toward low-cost gene therapy: mRNA-based therapeutics for treatment of inherited retinal diseases

Trends in Molecular Medicine

IF13.8

2024-02-01

OAAI

Antas, Pedro; Carvalho, Claudia; Cabral-Teixeira, Joaquim; de Lemos, Luisa; Seabra, Miguel C.

Impaired Lysosome Reformation in Chloroquine-Treated Retinal Pigment Epithelial Cells

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

IF4.7

2023-08-07

OAAI

Cardoso, M. Helena; Hall, Michael J.; Burgoyne, Thomas; Fale, Pedro; Storm, Tina; Escrevente, Cristina; Antas, Pedro; Seabra, Miguel C.; Futter, Clare E.

Deacidification of endolysosomes by neuronal aging drives synapse loss

TRAFFIC

IF2.5

2023-05-23

OAAI

Burrinha, Tatiana; Cunha, Cesar; Hall, Michael J.; Lopes-da-Silva, Mafalda; Seabra, Miguel C.; Almeida, Claudia Guimas

Genipin prevents alpha-synuclein aggregation and toxicity by affecting endocytosis, metabolism and lipid storage

NATURE COMMUNICATIONS

IF15.7

2023-04-06

OAAI

Rosado-Ramos, Rita; Pocas, Goncalo M.; Marques, Daniela; Foito, Alexandre; Sevillano, David M.; Lopes-da-Silva, Mafalda; Goncalves, Luis G.; Menezes, Regina; Ottens, Marcel; Stewart, Derek; de Opakua, Alain Ibanez; Zweckstetter, Markus; Seabra, Miguel C.; Mendes, Cesar S.; Outeiro, Tiago Fleming; Domingos, Pedro M.; Santos, Claudia N.

Choroidal Vascular Impairment in Intermediate Age-Related Macular Degeneration 中等年龄相关性黄斑变性的脉络膜血管损害

DIAGNOSTICS

IF3.3

2022-05-22

OAAI

Flores, Rita; Carneiro, Angela; Neri, Guilherme; Fradinho, Ana C.; Quenderra, Bruno; Barata, Maria Joao; Tenreiro, Sandra; Seabra, Miguel C.

Melanocore uptake by keratinocytes occurs through phagocytosis and involves protease-activated receptor-2 internalization

TRAFFIC

IF2.5

2022-05-15

OAAI

Moreiras, Hugo; Bento-Lopes, Liliana; Neto, Matilde V.; Escrevente, Cristina; Cabaco, Luis C.; Hall, Michael J.; Ramalho, Jose S.; Seabra, Miguel C.; Barral, Duarte C.

Current methods to analyze lysosome morphology, positioning, motility and function

TRAFFIC

IF2.5

2022-04-24

OAAI

Barral, Duarte C.; Staiano, Leopoldo; Guimas Almeida, Claudia; Cutler, Dan F.; Eden, Emily R.; Futter, Clare E.; Galione, Antony; Marques, Andre R. A.; Medina, Diego Luis; Napolitano, Gennaro; Settembre, Carmine; Vieira, Otilia V.; Aerts, Johannes M. F. G.; Atakpa-Adaji, Peace; Bruno, Gemma; Capuozzo, Antonella; De Leonibus, Elvira; Di Malta, Chiara; Escrevente, Cristina; Esposito, Alessandra; Grumati, Paolo; Hall, Michael J.; Teodoro, Rita O.; Lopes, Susana S.; Luzio, J. Paul; Monfregola, Jlenia; Montefusco, Sandro; Platt, Frances M.; Polishchuck, Roman; De Risi, Maria; Sambri, Irene; Soldati, Chiara; Seabra, Miguel C.

Reconstructed human pigmented skin/epidermis models achieve epidermal pigmentation through melanocore transfer

PIGMENT CELL & MELANOMA RESEARCH

IF2.6

2022-04-07

OAAI

Hall, Michael J.; Lopes-Ventura, Sara; Neto, Matilde V.; Charneca, Joao; Zoio, Patricia; Seabra, Miguel C.; Oliva, Abel; Barral, Duarte C.

Retinal Progression Biomarkers of Early and Intermediate Age-Related Macular Degeneration 早期和中期年龄相关性黄斑变性的视网膜进展生物标志物

LIFE-BASEL

IF3.4

2021-12-27

OAAI

Flores, Rita; Carneiro, Angela; Tenreiro, Sandra; Seabra, Miguel C.

Formation of Lipofuscin-Like Autofluorescent Granules in the Retinal Pigment Epithelium Requires Lysosome Dysfunction

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

IF4.7

2021-07-27

OAAI

Escrevente, Cristina; Falcao, Ana S.; Hall, Michael J.; Lopes-da-Silva, Mafalda; Antas, Pedro; Mesquita, Miguel M.; Ferreira, Ines S.; Cardoso, M. Helena; Oliveira, Daniela; Fradinho, Ana C.; Ciossek, Thomas; Nicklin, Paul; Futter, Clare E.; Tenreiro, Sandra; Seabra, Miguel C.

Symmetric arrangement of mitochondria:plasma membrane contacts between adjacent photoreceptor cells regulated by Opa1

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-06-22

OAAI

Meschede, Ingrid P.; Ovenden, Nicholas C.; Seabra, Miguel C.; Futter, Clare E.; Votruba, Marcelo; Cheetham, Michael E.; Burgoyne, Thomas

Rab27a Contributes to the Processing of Inflammatory Pain in Mice

CELLS

IF5.2

2020-06-18

OAAI

Gross, Tilman; Wack, Gesine; Syhr, Katharina M. J.; Tolmachova, Tanya; Seabra, Miguel C.; Geisslinger, Gerd; Niederberger, Ellen; Schmidtko, Achim; Kallenborn-Gerhardt, Wiebke

Transfer of extracellular vesicle-microRNA controls germinal center reaction and antibody production 细胞外囊泡的转移-microRNA控制生发中心反应和抗体产生

EMBO REPORTS

IF6.2

2020-02-19

OAAI

Fernandez-Messina, Lola; Rodriguez-Galan, Ana; de Yebenes, Virginia G.; Gutierrez-Vazquez, Cristina; Tenreiro, Sandra; Seabra, Miguel C.; Ramiro, Almudena R.; Sanchez-Madrid, Francisco

The exocyst is required for melanin exocytosis from melanocytes and transfer to keratinocytes

PIGMENT CELL & MELANOMA RESEARCH

IF2.6

2019-11-19

OAAI

Moreiras, Hugo; Pereira, Francisco J. C.; Neto, Matilde V.; Bento-Lopes, Liliana; Festas, Tiago C.; Seabra, Miguel C.; Barral, Duarte C.

Remodeling of the Basal Labyrinth of Retinal Pigment Epithelial Cells With Osmotic Challenge, Age, and Disease

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

IF4.7

2019-06-13

OAAI

Hayes, Matthew J.; Burgoyne, Thomas; Wavre-Shapton, Silene T.; Tolmachova, Tanya; Seabra, Miguel C.; Futter, Clare E.

Nucleotide exchange factor Rab3GEP requires DENN and non- DENN elements for activation and targeting of Rab27a

JOURNAL OF CELL SCIENCE

IF3.6

2019-04-30

OAAI

Sanza, Paolo; Evans, Richard D.; Briggs, Deborah A.; Cantero, Marta; Montoliu, Lluis; Patel, Shyamal; Sviderskaya, Elena V.; Itzen, Aymelt; Figueiredo, Ana C.; Seabra, Miguel C.; Hume, Alistair N.

研究方向