Christophe Le Tourneau - Publications, H-index & Citations

Christophe Le Tourneau

Institut Curie

67H指数

629论文数

2.3W被引数

收录论文 218

发表时间

A viral-based individualized neoantigen vaccine as adjuvant treatment in resected head and neck squamous cell carcinoma: a randomized Phase I trial 基于病毒载体的个体化新抗原疫苗作为头颈部鳞状细胞癌切除术后辅助治疗：一项随机I期临床试验

Nature Communications

IF15.7

2026-08-17

OAAI

Christian Ottensmeier; Jean-Pierre Delord; Ana Lalanne; Camille Jamet; Anne-Laure Le Gac; Katell Bidet Huang; Benoît Grellier; Jules Deforges; Maud Brandely; Eric Quéméneur; Bérangère Bastien; Annette Tavernaro; Gisèle Lacoste; Valérie Schoettel; Clémentine Spring-Giusti; Nathalie Silvestre; Jean-Baptiste Marchand; Sylvain Robin; Emmanuelle Dochy; Maurizio Ceppi; Alessandro Riva; Naoko Yamagata; Per Brattas; Kazuhide Onoguchi; Yoshiko Yamashita; Hugues Fontenelle; Mariana Eggert Martinez; Oliver Baker; Terry Jones; Andrew Schache; Eliane Piaggio; Kaïdre Bendjama; Olivier Lantz; Christophe Le Tourneau

Efficacy of buparlisib according to PIK3CA mutation status in recurrent or metastatic head and neck squamous cell carcinoma: A multicenter phase II trial 根据PIK3CA突变状态评估buparlisib在复发或转移性头颈鳞状细胞癌中的疗效：一项多中心II期临床试验

Oral Oncology

IF3.9

2026-05-13

PREAI

Thibault Gauduchon; Laurence Digue; Céline Ferlay; Isabelle Treilleux; Qing Wang; Valéry Attignon; Gautier Lefebvre; Nuria Kotecki; Amaury Daste; Caroline Even; Sophie Couchon-Thaunat; Aurélie Guyennon; Frédéric Peyrade; Didier Cupissol; Benoît You; Christophe Le Tourneau; Séverine Tabone-Eglinger; Gwenaelle Garin; David Pérol; Jérome Fayette

Personalized and HPV cancer vaccines in head and neck squamous cell carcinoma: from concept to clinical implementation 个性化及HPV癌症疫苗在头颈鳞状细胞癌中的应用：从概念到临床实施

Translational Oncology

IF4.1

2026-03-13

OAAI

Daria Maria Filippini; Christophe Le Tourneau

Accelerating recruitment in clinical trials: A strategic challenge 加速临床试验中的招募：一项战略挑战

Therapie

IF1.8

2026-01-01

PREAI

Deplanque, Dominique; Galaup, Ariane; Trillou, Christine; Barthelemy, Philippe; Bayle, Arnaud; Da Cruz, Lionel; Domain, Erik; Duruisseaux, Michael; Fouret, Cecile; Gambotti, Laetitia; Girault, Cecile; Gonthier, Damien; Guerin, Aurelie; Hommais, Antoine; Hulot, Jean-Sebastien; Ko, Dorothee; Lang, Marie; Laugel, Vincent; Laviolle, Bruno; Le Tourneau, Christophe; Oheix, Julie; Simon, Tabassome; Skrzypski, Jeremy

Benchmarking progression-free survival ratio as primary endpoint in precision oncology clinical trials 将无进展生存比作为精准肿瘤学临床试验的主要终点进行基准测试

npj Precision Oncology

IF8

2025-12-15

OAAI

Federico Nichetti; Jennifer Hüllein; Pauline du Rusquec; Erin Pleasance; Li Chen; Andreas Mock; Peter Horak; Paolo Ambrosini; Simone Rota; Monica Niger; Luca Agnelli; Gabriele Tinè; Dominic Edelmann; Christophe Le Tourneau; Janessa Laskin; Giancarlo Pruneri; Chi Wang; Daniel Hübschmann; Filippo de Braud; Stefan Fröhling; Luigi Mariani

Management and survival of patients with cancer of unknown primary discussed by a French national multidisciplinary tumour board: a retrospective analysis 法国国家多学科肿瘤委员会讨论的未知原发灶癌症患者的管理及生存：一项回顾性分析

The Lancet Regional Health - Europe

IF0

2025-11-07

OAAI

Célia Dupain; Nicolas Jacquin; Aurélien Latouche; Zoé Nevière; Pierre Gestraud; Abderaouf Hamza; Kenza Nedara; Vincent Cockenpot; Janick Selves; Yves Allory; Laëtitia Chanas; Maud Milder; Isabelle Soubeyran; Hélène Blons; Anna Patrikidou; Axel de Bernardi; Julien Masliah-Planchon; Odette Mariani; Etienne Rouleau; Fabienne Escande; Sandrine Boyault; Pierre Saintigny; Florence de Fraipont; Pierre Blanc; Jennifer Wong; Camille Tlemsani; Isabelle Guillou; Julie Flavius; Noemie Fuentealba; Maud Kamal; Ivan Bièche; Nicolas Servant; Christophe Le Tourneau; Sarah Watson

MOVIE phase II trial of tremelimumab plus durvalumab combined with metronomic oral vinorelbine in patients with head and neck cancer MOVIE II期临床试验：曲美木单抗联合度伐利尤单抗与口服常规剂量长春瑞滨治疗头颈癌患者的疗效研究

ESMO Open

IF8.3

2025-11-06

OAAI

E. Borcoman; A. Hervieu; C. Cropet; E. Coquan; J. Guigay; F. Rolland; M. Bernadach; E. Charafe; F. Legrand; E. Dassé; C. Le Tourneau; A. Gonçalves

Acceptance of external control arms by HTA agencies: a review of oncology submissions in France, England, Germany and Norway from 2021 to 2023 HTA机构对外部对照的接受度：2021年至2023年法国、英格兰、德国和挪威肿瘤学提交案例的回顾

British Journal of Cancer

IF6.8

2025-09-12

PREAI

Matthias Monnereau; Jean-Pierre Delord; Stefan Michiels; Christophe Le Tourneau; Sebastien Marque; Louise Baschet; Thomas Filleron

Molecular analysis of lung adenocarcinomas from the SAFIR02-Lung cohort reveals new metastasis-associated copy-number alterations including frequent mutant-specific KRAS-allelic imbalance and identifies CDKN2A homozygous deletions as an independent biomarker of poor prognosis SAFIR02-Lung队列中肺腺癌的分子分析揭示了新的与转移相关的染色体拷贝数改变，包括频繁的突变特异性KRAS等位基因失衡，并将CDKN2A纯合子缺失鉴定为不良预后的独立生物标志物。

British Journal of Cancer

IF6.8

2025-09-11

PREAI

Abderaouf Hamza; Pierre Gestraud; Maryam Karimi; Alicia Tran-Dien; Laurène Syx; Sophie Vacher; Quentin Peretti; Ludovic Lacroix; Valery Attignon; Isabelle Soubeyran; Pascal Jézéquel; David Planchard; Samia Melaabi; Trenton Dailey-Chwalibóg; Marta Jimenez; Stefan Michiels; Nicolas Servant; Christophe Le Tourneau; Nicolas Girard; Fabrice André; Benjamin Besse; Maud Kamal; Fabrice Barlesi; Ivan Bièche

Efficacy of pembrolizumab and vorinostat combination in patients with recurrent and/or metastatic squamous cell carcinomas: a phase 2 basket trial 帕博利珠单抗和伏立诺他联合治疗复发性/转移性鳞状细胞癌的疗效：一项II期篮式试验

Nature Cancer

IF28.5

2025-06-30

OAAI

Edith Borcoman; Bastien Cabarrou; Miguel Francisco; Frédéric Bigot; François Ghiringhelli; Damien Vansteene; François Legrand; Maral Halladjian; Célia Dupain; Olivia Le Saux; Clelia Coutzac; Christian Borel; Raphael Chaltiel; Benoit You; Carlos Gomez-Roca; Sophie Cousin; Elodie Coquan; Aurélien Lambert; Esma Saada-Bouzid; Xavier Durando; Mathilde Saint-Ghislain; Gianmaria Frige; Elena Guerini-Rocco; Maria Manuela Tonini; Ivan Bièche; Zahra Castel-Ajgal; Grégoire Marret; Marie-Paule Sablin; Emmanuelle Jeannot; Fabrice Andre; Thomas Filleron; Marta Jimenez; Luca Mazzarella; Nicolas Servant; Maud Kamal; Christophe Le Tourneau

Clinical landscape for patients with head and neck cancers enrolled in phase I trials at a tertiary referral center 在三级转诊中心参与I期临床试验的头颈癌患者的临床现状

Therapeutic Advances in Medical Oncology

IF4.2

2025-06-30

OAAI

Daria Maria Filippini; Raphael Sanchez; Etienne Bastien; Nicolas Jacquin; Alexandro Paccapelo; Caroline Nhy; Jerzy Klijanienko; Valentin Calugaru; Anne Chilles; Wahib Ghanem; Guillaume Rougier; Antoine Dubray Vautrin; Nathalie Badois; Maria Lesnik; Olivier Choussy; Marie Paule Sablin; Christophe Le Tourneau; Grégoire Marret

Multicollinearity and redundancy of the PET radiomic feature set PET影像组学特征集的多重共线性与冗余性

EUROPEAN RADIOLOGY

IF4.7

2025-05-07

OAAI

Noortman, Wyanne A.; Vriens, Dennis; Bussink, Johan; Meijer, Tineke W. H.; Aarntzen, Erik H. J. G.; Deroose, Christophe M.; Lhommel, Renaud; Aide, Nicolas; Le Tourneau, Christophe; de Koster, Elizabeth J.; Oyen, Wim J. G.; Triemstra, Lianne; Ruurda, Jelle P.; Vegt, Erik; de Geus-Oei, Lioe-Fee; van Velden, Floris H. P.

A phase II study of monalizumab and durvalumab in patients with recurrent/metastatic squamous cell carcinoma of the head and neck: results of the I2 cohort of the EORTC-HNCG-1559 trial (UPSTREAM)一项关于monalizumab和durvalumab在复发性/转移性头颈鳞状细胞癌患者中的II期研究：EORTC-HNCG-1559试验（UPSTREAM）中I2组的成果

ESMO OPEN

IF8.3

2025-05-01

OAAI

Galot, R.; Le Tourneau, C.; Licitra, L.; Guigay, J.; Kong, A.; Tinhofer, I.; Even, C.; Daste, A.; Henry, S.; Borel, C.; Abdeddaim, C.; Seront, E.; Prevost, J. B.; Rutten, A.; Saada-Bouzid, E.; Rolland, F.; Bonomo, P.; Rasschaert, M.; Dirix, L.; Olungu, C.; Tsechilidou, K.; Govaerts, A. S.; Fortpied, C.; Joaquim, A.; Machiels, J. P.

Deciphering molecular relapse and intra-tumor heterogeneity in non-metastatic resectable head and neck squamous cell carcinoma using circulating tumor DNA

ORAL ONCOLOGY

IF3.9

2025-01-01

PREAI

Marret, Gregoire; Lamy, Constance; Vacher, Sophie; Cabel, Luc; Sene, Mathieu; Ahmanache, Ladidi; Courtois, Laura; El Beaino, Zakhia; Klijanienko, Jerzy; Martinat, Charlotte; Servant, Nicolas; Kamoun, Choumouss; Halladjian, Maral; Bronzini, Thierry; Balsat, Cedric; Laes, Jean-Francois; Prevot, Aubray; Sauvage, Sebastien; Lienard, Maxime; Martin, Emmanuel; Genin, Berengere; Badois, Nathalie; Lesnik, Maria; Dubray-Vautrin, Antoine; Choussy, Olivier; Ghanem, Wahib; Taouachi, Rabah; Planchon, Julien Masliah; Bieche, Ivan; Le Tourneau, Christophe; Kamal, Maud

Paving the path towards tissue-agnostic drug approval in oncology

ANNALS OF ONCOLOGY

IF65.4

2024-11-01

PREAI

Le Tourneau, C.; Bieche, I.; Kamal, M.

Comprehensive biomarker and modeling approach to support dose finding for BI 836880, a VEGF/Ang-2 inhibitor

JOURNAL OF TRANSLATIONAL MEDICINE

IF7.5

2024-10-14

OAAI

Keller, Sascha; Kunz, Ulrich; Schmid, Ulrike; Beusmans, Jack; Buechert, Martin; He, Min; Jayadeva, Girish; Le Tourneau, Christophe; Luedtke, Doreen; Niessen, Heiko G.; Oum'hamed, Zohra; Pleiner, Sina; Wang, Xiaoning; Graeser, Ralph

Methylation, Gene Expression, and Risk Genotypes at the TERT-CLPTM1L Locus in Cervical Cancer

MOLECULAR CARCINOGENESIS

IF3.2

2024-10-01

PREAI

Ramachandran, Dhanya; Mao, Qianqian; Liao, Dandan; Kamal, Maud; Schuermann, Peter; Eisenblaetter, Rieke; Geffers, Robert; Balint, Balazs; Lecompte, Lolita; Servant, Nicolas; Cherif, Linda Larbi; Lamy, Constance; Baulande, Sylvain; Legoix, Patricia; Le Tourneau, Christophe; Latouche, Aurelien; Hillemanns, Peter; Scholl, Suzy; Doerk, Thilo

Evasion of apoptosis and treatment resistance in squamous cell carcinoma of the head and neck 头颈部鳞状细胞癌的凋亡逃避和治疗抵抗

CANCER TREATMENT REVIEWS

IF10.5

2024-09-01

OAAI

O'Leary, Ben; Skinner, Heath; Schoenfeld, Jonathan; Licitra, Lisa; Le Tourneau, Christophe; Esdar, Christina; Schroeder, Andreas; Salmio, Satu; Psyrri, Amanda

Next-generation sequencing (NGS) in routine care: Medical practice in 24 countries from the pan-cancer WAYFIND-R registry 下一代测序(NGS)在常规护理中的应用：泛癌种WAYFIND-R登记研究中的24国医疗实践

ANNALS OF ONCOLOGY

IF65.4

2024-09-01

PREAI

Le Tourneau, C.; Dienstmann, R.; Hackshaw, A.; Geissler, J.; Ferro, A.; Cheese, E.; Schirghuber, E.; Blay, J-Y.

Biomarker analysis of the phase III KEYNOTE-040 study of pembrolizumab (pembro) versus methotrexate, docetaxel, or cetuximab (SOC) for recurrent/metastatic (R/M) head and neck squamous cell carcinoma (HNSCC)KEYNOTE-040研究第三阶段中，pembrolizumab（pembro）与甲氨蝶呤、多西他赛或西妥昔单抗（SOC）用于复发性/转移性（R/M）头颈鳞状细胞癌（HNSCC）的生物标志物分析

ANNALS OF ONCOLOGY

IF65.4

2024-09-01

PREAI

Soulieres, D.; Le Tourneau, C.; Machiels, J-P.; Burtness, B.; Harrington, K. J.; Shen, J.; Tao, J.; Webber, A.; Vajdi, A.; Loboda, A.; Lerman, N.; Gumuscu, B.; Licitra, L. F. L.

研究方向