Ralf‐Dieter Hofheinz - Publications, H-index & Citations

Ralf‐Dieter Hofheinz

universität heidelberg

57H指数

606论文数

1.9W被引数

收录论文 141

发表时间

STAR-TREC and TESAR trials: strengthening the evidence for organ preservation in rectal cancer STAR-TREC和TESAR试验：加强直肠癌保肛治疗的证据

Lancet Oncology

IF35.9

2026-08-23

PREAI

Emmanouil Fokas; Ralf-Dieter Hofheinz

Chemotherapy for patients with circulating tumour DNA positive, stage II colon cancer (CIRCULATE) – an AIO / ABCSG trial 循环肿瘤DNA阳性、II期结肠癌患者的化疗（CIRCULATE）——一项AIO/ABCSG试验

Annals of Oncology

IF65.4

2026-05-31

OAAI

G. Folprecht; S. Stasik; A. Reinacher-Schick; L. Weiss; E. Goekkurt; L. Jacobasch; L. Conradi; A. Kröcher; R.-D. Hofheinz; R. Liersch; U.M. Martens; J. Chater; M. Fuchs; J.U. Riera Knorrenschild; J. Schubert; A. Klimova; L. Reinhardt; C. Sperling; J. von Tresckow; J. Weitz

Aflibercept and 5-FU vs. FOLFOX as 1st line treatment for older adults or frail elderly patients with metastatic colorectal cancer – the randomized phase 2 AIO / IKF ELDERLY trial (AIO-KRK-0117 / IKF 629)阿柏西普和5-FU对比FOLFOX作为老年或虚弱老年患者转移性结直肠癌的一线治疗方案——随机II期AIO / IKF ELDERLY试验（AIO-KRK-0117 / IKF 629）。

European Journal of Cancer

IF7.1

2026-03-24

PREAI

Ralf-Dieter Hofheinz; Ludwig Fischer von Weikersthal; Tobias Dechow; Reinhard Depenbusch; Christian Müller; Thorsten O. Goetze; Silvan Becker; Alexander Kiani; Thomas Ettrich; Alexander Schmittel; Holger Schulz; Matthias Ebert; Disorn Sookthai; Claudia Volk; Claudia Pauligk; Maria Loose; Salah-Eddin Al-Batran; Sylvie Lorenzen

Preoperative Immunotherapy in Oncology 肿瘤学中的术前免疫疗法

Deutsches Arzteblatt International

IF7.1

2026-01-23

PREAI

Hofheinz, Ralf-Dieter; Lorenzen, Sylvie; Sebastian, Martin; Bolukbas, Servet; Fichtner-Feigl, Stefan; Loibl, Sibylle

Treatment landscape from first- to third-line therapy and quality of life data of patients with pancreatic cancer from the prospective German PARAGON (Platform for Outcome, Quality of Life, and Translational Research on Pancreatic Cancer) registry (IKF-PARAGON study)从一线到三线治疗的胰腺癌患者治疗格局及生活质量数据，来自德国PARAGON（胰腺癌结局、生活质量及转化研究平台）登记研究（IKF-PARAGON研究）。

INTERNATIONAL JOURNAL OF CANCER

IF4.7

2025-12-01

OAAI

Goetze, Thorsten O.; Al-Batran, Salah-eddin; Liersch, Ruediger; Scheuer, Lars; Goehler, Thomas; Kaiser, Ulrich; Denzlinger, Claudio; Brandl, Stephan; Pink, Daniel; Uhlig, Jens; Maasberg, Michael; Loose, Maria; Schaaf, Marina; Sookthai, Disorn; Zapf, Bianca; Pauligk, Claudia; Habibzade, Timursah; Hofheinz, Ralf-dieter; Koch, Christine

Expert-guided approaches to complementary interventions for common side effects of cancer therapies: a practice-based perspective from integrative oncology centers in Baden-Württemberg; Germany 专家指导的癌症治疗常见副作用补充干预方法：来自德国巴登-符腾堡州整合肿瘤中心的实践视角

Frontiers in Oncology

IF3.3

2025-11-06

OAAI

Marcela Winkler; Thomas Breitkreuz; Jürgen Brust; Stefanie Frenzel; Julia Gottfried; Wolfgang Heyl; Stefan Hiller; Ralf-Dieter Hofheinz; Meike Jocher; Elke Kaschdailewitsch; Hans Lampe; Maria Livas; Heike Mönnich; Claudia Raichle; Jane Reutter; Jens-Paul Seldte; Sigune Singer-Bayrle; Theresa Wagner; Anne-Kathrin Weise; Klaus Kramer

Perioperative pembrolizumab, trastuzumab and FLOT in HER2-positive localized esophagogastric adenocarcinoma: a phase 2 trial 围手术期帕博利珠单抗、曲妥珠单抗及FLOT方案在HER2阳性局限性食管胃腺癌中的疗效：一项Ⅱ期临床试验

Nature Medicine

IF50

2025-10-18

OAAI

Alexander Stein; Eray Goekkurt; Salah-Eddin Al-Batran; Nicolas Moosmann; Thomas J. Ettrich; Thorsten Goetze; Barbara Gruen; Nils Homann; Sylvie Lorenzen; Ralf-Dieter Hofheinz; Viktor Rempel; Gabriele Siegler; Christian Müller; Benjamin Thiele; Tobias Broering; Mariana Santos Cruz; Claudia Pauligk; Mascha Binder; Joseph Tintelnot

Structured Magnetic Resonance Imaging Assessment Improves Diagnosis of Pathological Complete Response in Rectal Cancer after Neoadjuvant Chemoradiation 结构化磁共振成像评估可提高直肠癌新辅助放化疗后病理完全缓解的诊断。

ONCOLOGY RESEARCH AND TREATMENT

IF1.6

2025-09-01

PREAI

Li, Moying; Dieckmann, Tobias; Herrle, Florian; Hofheinz, Ralf-Dieter; Hielscher, Thomas; Hertel, Alexander; Schweitzer, Sophia; Hetjens, Svetlana; Betge, Johannes; Belle, Sebastian; Schulte, Nadine; Reissfelder, Christoph; Boda-Heggemann, Judit; Dreher, Constantin; Brochhausen, Christoph; Ebert, Matthias P.; Froelich, Matthias F.; Zhan, Tianzuo

Predictors of Successful Whole-Body Hyperthermia in Cancer Patients: Target Temperature Achievement and Safety Analysis 癌症患者全身高温疗法成功的影响因素：目标温度达成与安全性分析

Cancers 2025, Vol. 17, Page 2716

IF4.4

2025-08-21

PREAI

Anna Lena Hohneck; Vivien Schmitz-Solheid; Deniz Gencer; Maik Schroeder; Hartmut Riess; Annette Gerhards; Iris Burkholder; Stefan Heckel-Reusser; Julia Gottfried; Ralf-Dieter Hofheinz

Individually compounded multi-chamber vs. standardized parenteral nutrition bags in solid tumors–A randomized clinical trial (IKF-010)个体化配制的多腔袋与标准化肠外营养袋在实体瘤中的应用比较——一项随机临床试验（IKF-010）

clinical nutrition

IF2.6

2025-06-24

OAAI

Thorsten Oliver Goetze; Ralf-Dieter Hofheinz; Ingeborg Roetzer; Wolfgang Blau; Thomas Zander; Kim Barbara Luley; Philipp Ivanyi; Matthias Groschek; Janine Kreiss-Sender; Christina Baur; Thomas Wolff; Barbara Wenning; Dirk Behringer; Florian Weißinger; Annegret Kunitz; Barbara Tschechne; Christiane Decker-Baumann; Melanie Frank; Luisa Wohn; Johanna Riedel; Georg Martin Haag

Localised rectal cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up☆局部直肠 cancer：ESMO 临床实践指南（用于诊断、治疗和随访）☆

Annals of Oncology

IF65.4

2025-05-22

PREAI

R.-D. Hofheinz; E. Fokas; L. Benhaim; T.J. Price; D. Arnold; R. Beets-Tan; M.G. Guren; G.A.P. Hospers; S. Lonardi; I.D. Nagtegaal; R.O. Perez; A. Cervantes; E. Martinelli

Quality of Life After Two Sequences of Total Neoadjuvant Treatment in Patients With Locally Advanced Rectal Cancer in the Randomized CAO/ARO/AIO-12 Phase 2 Trial CAO/ARO/AIO-12随机对照试验第2阶段中，局部晚期直肠癌患者接受两种序贯总新辅助治疗后生活质量研究

International Journal of Radiation Oncology*Biology*Physics

IF0

2025-05-21

OAAI

Rebekka Kosmala; Adriana Salazar Hammann; Patrick Paulus; Marcus Zimmermann; Andrea Wittig-Sauerwein; Christoph-Thomas Germer; Michael Ghadimi; Ralf-Dieter Hofheinz; Markus Diefenhardt; Emmanouil Fokas; Claus Rödel; Bülent Polat

Chemotherapy before or after preoperative chemoradiotherapy and surgery for locally advanced rectal cancer: 5-year results of the CAO/ARO/AIO-12 trial - a general pairwise comparison 术前或术后化疗联合新辅助放化疗及手术用于局部晚期直肠癌：CAO/ARO/AIO-12试验的5年结果——一项总体成对比较

ESMO OPEN

IF8.3

2025-03-01

OAAI

Diefenhardt, M.; Kosmala, R.; Fleischmann, M.; Martin, D.; Hofheinz, R. D.; Ghadimi, M.; Roedel, C.; Polat, B.; Fokas, E.

Prognosis and quality of life in patients with locally advanced rectal cancer after abdominoperineal resection in the CAO/ARO/AIO-04 randomized phase 3 trial

SCIENTIFIC REPORTS

IF3.9

2025-02-13

OAAI

Gaedcke, Jochen; Sahrhage, Malte; Ebeling, Marcel; Azizian, Azadeh; Ruehlmann, Felix; Bernhardt, Markus; Grade, Marian; Bechstein, Wolf Otto; Germer, Christoph-Thomas; Gruetzmann, Robert; Piso, Pompiliu; Hofheinz, Ralf-Dieter; Staib, Ludger; Beissbarth, Tim; Kosmala, Rebekka; Fokas, Emmanouil; Roedel, Claus; Ghadimi, Michael

mFOLFOX6 versus mFOLFOX6 D aflibercept as neoadjuvant treatment in MRI-defined T3-rectal cancer: a randomized phase-II-trial of the German Rectal Cancer Study Group (CAO/ARO/AIO 0214) and the ABCSG (R-06) (vol 9, 103703, 2024)

ESMO OPEN

IF8.3

2025-02-01

OAAI

Hofheinz, R. -D.; Herrle, F.; Dechow, T.; von Weikersthal, L. F.; Welslau, M.; Lettmaier, S.; Burkart, C.; Kubicka, S.; Kochen, L.; Merx, K.; Krause, K.; Ebert, M.; Roedel, C.; Fokas, E.; Ghadimi, M.; Reissfelder, C.; Gaiser, T.

Differential effects of sound interventions tuned to 432 Hz or 443 Hz on cardiovascular parameters in cancer patients: a randomized cross-over trial

BMC COMPLEMENTARY MEDICINE AND THERAPIES

IF3.4

2025-01-22

OAAI

Hohneck, Anna; Rodriguez, anxelo Maia; Weingaertner, Simone; Merx, Kirsten; Sarodnick, Felicitas; von Gagern, Fritjof; Mavratzas, Athanasios; Burkholder, Iris; Schumacher, Gerhard; Hofmann, Wolf-Karsten; Hofheinz, Ralf-Dieter

Immune Checkpoint Blockade Combined with AbnobaViscum® Therapy Is Linked to Improved Survival in Advanced or Metastatic Non-Small-Cell Lung Cancer Patients: A Registry Study in Accordance with the ESMO Guidance for Reporting Real-World Evidence

PHARMACEUTICALS

IF4.8

2024-12-18

OAAI

Schad, Friedemann; Thronicke, Anja; Hofheinz, Ralf-Dieter; Klein, Reinhild; Grabowski, Patricia; Oei, Shiao Li; Wuestefeld, Hannah; Grah, Christian

Chemoradiotherapy plus induction or consolidation chemotherapy as total neoadjuvant therapy for locally advanced rectal cancer: Pooled analysis of the CAO/ARO/AIO-12 and the OPRA randomized phase 2 trials 放化疗加诱导或巩固化疗作为局部晚期直肠癌的总新辅助治疗: CAO/ARO/AIO-12和OPRA随机2期试验的汇总分析

EUROPEAN JOURNAL OF CANCER

IF7.1

2024-10-01

PREAI

Fokas, Emmanouil; Williams, Hannah; Diefenhardt, Markus; Lin, Sabrina; Qin, Li-Xuan; Piso, Pompiliu; Dapper, Hendrik; Germer, Christoph-Thomas; Gruetzmann, Robert; Friede, J. Tim; Smith, J. Joshua; Saltz, Leonard B.; Wu, Abraham J.; Weiser, Martin R.; Omer, Dana; Ghadimi, Michael; Hofheinz, Ralf-Dieter; Garcia-Aguilar, Julio; Roedel, Claus

Functional status and quality of life in older patients with advanced esophageal squamous cell cancer receiving second-line nivolumab ± ipilimumab therapy: A post hoc analysis of the phase 2, multicenter RAMONA study

JOURNAL OF GERIATRIC ONCOLOGY

IF2.7

2024-09-01

PREAI

Li, Moying; Meindl-Beinker, Nadja M.; Maenz, Martin; Betge, Johannes; Schulte, Nadine; Zhan, Tianzuo; Hofheinz, Ralf-Dieter; Vogel, Arndt; Angermeier, Stefan; Bolling, Claus; de Wit, Maike; Jakobs, Ralf; Karthaus, Meinolf; Stocker, Gertraud; Thuss-Patience, Peter; Leidig, Tobias; Bauer, Hans; Ebert, Matthias P.; Haertel, Nicolai

Modified FOLFOX plus/minus nivolumab and ipilimumab vs FLOT plus nivolumab in patients with previously untreated advanced or metastatic adenocarcinoma of the stomach or gastroesophageal junction: Final results of the IKF-AIO-Moonlight trial 改良FOLFOX联合或不联合纳武利尤单抗和伊匹木单抗对比FLOT联合纳武利尤单抗治疗既往未接受治疗的胃或胃食管结合部腺癌晚期或转移性患者的最终结果：IKF-AIO-Moonlight试验

ANNALS OF ONCOLOGY

IF65.4

2024-09-01

PREAI

Lorenzen, S.; Goetze, T. O.; Thuss-Patience, P. C.; Knorrenschild, J. Riera; Goekkurt, E.; Dechow, T. N.; Ettrich, T. J.; Hofheinz, R. D.; Luley, K.; Pink, D.; Lindig, U.; Folprecht, G.; Schuch, G.; Bitzer, M.; Heinemann, V.; Angermeier, S.; Bolling, C.; Junge, S.; Pauligk, C.; Al-Batran, S-E.

研究方向