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L

Laura K. Mackay

University of Melbourne
H指数:47
被引数:1.2万

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Tumor-resident T cells and dendritic cells form an in situ archetype during immunotherapy response in melanoma

肿瘤内T细胞和树突状细胞在黑色素瘤免疫治疗反应中形成原位原型

Nature Communications
IF15.7
2026-06-010
PRE
Di Pietro, Andrea; Au, Lewis; Crock, Patrick; Thio, Niko; Pizzolla, Angela; Nguyen, Thu Ngoc; Macdonald, Sean; Chalmers, Hugh; Zhu, Ruiqing; Airaghi, Alessia; Molden-Hauer, Tristan; Bacac, Marina; Schwalie, Petra; Schlenker, Ramona; Levesque, Mitchell P.; Mailer, Sonia; Barnes-Cullen, Kristy; Winch, Karen; Chan, Joanna; Yeung, George Au; Spain, Lavinia; Rao, Aparna D.; Sandhu, Shahneen; Gyorki, David E.; McArthur, Grant A.; Mackay, Laura K.; Neeson, Paul J.
Flt3L-mediated tumor cDC1 expansion enhances immunotherapy by priming stem-like CD8+ T cells in lymph nodes

Flt3L-mediated肿瘤cDC1扩增通过引发淋巴结中的干细胞样cd8t 细胞来增强免疫治疗

Nature Immunology
IF27.6
2026-02-100
PREAI
Junyun Lai; Cheok Weng Chan; Jesse D. Armitage; Katherine M. Audsley; Yu-Kuan Huang; Emily B. Derrick; Laura S. Carstensen; Christina M. Scheffler; Matt E. Jones; Kevin Sek; Nicola Principe; Joelle S. Kim; Imran G. House; Amanda X. Y. Chen; Kah Min Yap; Jim Middelburg; Isabelle Munoz; Dat Nguyen; Junming Tong; Thang X. Hoang; Kirsten L. Todd; Maximilien Evrard; Jonathan Chee; Laura K. Mackay; Alistair R. R. Forrest; Ian A. Parish; Anthony Bosco; Jason Waithman; Paul A. Beavis; Phillip K. Darcy
γδ T cell-derived IL-4 initiates CD8+ T cell immunity

Γ δ T细胞源性IL-4启动CD8 T细胞免疫

Nature Immunology
IF27.6
2026-01-300
OAAI
Shirley Le; Nick Dooley; Declan Murphy; Shangyi Liu; Luke C. Gandolfo; Zhengyu Ge; Rose May; Anton Cozijnsen; Thomas N. Burn; Charlie Jennison; Annabell Bachem; Calvin Xu; Hui-Fern Koay; Jan Schröder; Damian Oyong; Mayimuna Nalubega; Enny Kenangalem; Stephanie Gras; Ian A. Cockburn; Sammy Bedoui; Laura K. Mackay; Geoffrey I. McFadden; Daniel Fernandez-Ruiz; Michelle Boyle; William R. Heath; Lynette Beattie
Macrophage MR1 antigen presentation promotes MAIT cell immunity and lung microbiota modulation

Deng, J.; Yan, Y.; Zhang, X.; Walsh, C.J.; Montassier, E.; Sinha, D.; Wang, H.; Mousavizadeh, A.; Ashayeripanah, M.; Mak, J.Y.W.; et al. 巨噬细胞MR1抗原呈递促进MAIT细胞免疫和肺微生物群调节。Science 2026, 391, eadr6322. [Google Scholar] [CrossRef]

Science
IF45.8
2026-01-155
PRE
Deng, Jieru; Yan, Yuting; Zhang, Xiaoyue; Walsh, Calum J.; Montassier, Emmanuel; Sinha, Debajyoti; Wang, Huimeng; Mousavizadeh, Atieh; Ashayeripanah, Mitra; Mak, Jeffrey Y. W.; Koay, Hui-Fern; Poch, Tobias; Alexandre, Yannick O.; Mueller, Scott N.; Vasanthakumar, Ajithkumar; Stinear, Tim P.; Jameson, Vanta J.; Perez-Gonzalez, Alexis; Kingham, Jenny; Phan, Tri Giang; Potemkin, Nikita; Dryburgh, Lachlan; Schroeder, Jan; Fairlie, David P.; Mackay, Laura K.; Chen, Zhenjun; Cook, Laura; Hachani, Abderrahman; Corbett, Alexandra J.; Roquilly, Antoine; Villadangos, Jose A.; McWilliam, Hamish E. G.
Antigen reactivity defines tissue-resident memory and exhausted T cells in tumors

抗原反应性定义了肿瘤中的组织驻留记忆T细胞和耗竭T细胞。

Nature Immunology
IF27.6
2025-12-290
OAAI
Thomas N. Burn; Jan Schröder; Luke C. Gandolfo; Maleika Osman; Elanor N. Wainwright; Enid Y. N. Lam; Keely M. McDonald; Rachel B. Evans; Shihan Li; Daniel Rawlinson; Lachlan Dryburgh; Ali Zaid; Zoltan Maliga; Dominick Schienstock; Philippa Meiser; Hyun Jae Lee; Hongjin Lai; Marcela L. Moreira; Pirooz Zareie; Louis H-Y. Lee; Lutfi Huq; Susan N. Christo; Justine J. W. Seow; Keith A. Ching; Stéphane M. Guillaume; Kathy Knezevic; Simone L. Park; Maximilien Evrard; Jason Waithman; Thomas Gebhardt; Scott N. Mueller; Georgina E. Riddiough; Marcos V. Perini; Simon C. H. Tsao; Terence P. Speed; Peter K. Sorger; Sherene Loi; Francis R. Carbone; Stephanie Gras; Timothy S. Fisher; Bas J. Baaten; Mark A. Dawson; Laura K. Mackay
Guidelines for T cell nomenclature

T细胞命名指南

Nature Reviews Immunology
IF60.9
2025-11-180
OAAI
David Masopust; Amit Awasthi; Rémy Bosselut; David G. Brooks; Marcus Buggert; Kenji Chamoto; Weiguo Cui; Chen Dong; Donna L. Farber; Thomas Gebhardt; Carmen Gerlach; Ananda Goldrath; Philip D. Greenberg; J. Scott Hale; Adrian Hayday; Dirk Homann; Matteo Iannacone; Stephen C. Jameson; Marc K. Jenkins; Nikhil S. Joshi; Susan M. Kaech; Axel Kallies; Alice O. Kamphorst; Mark H. Kaplan; Paul Klenerman; Marco Künzli; Antonio Lanzavecchia; Georg M. Lauer; Enrico Lugli; Andrew D. Luster; Laura K. Mackay; M. Juliana McElrath; Scott N. Mueller; Zaza Ndhlovu; Thumbi Ndung’u; Pamela S. Ohashi; Annette Oxenius; Giuseppe Pantaleo; Marion Pepper; Louis J. Picker; Clare F. Quarnstrom; Gustavo Reyes-Terán; Mario Roederer; Pamela C. Rosato; Gonzalo Salgado-Montes de Oca; Federica Sallusto; Ton N. Schumacher; Daniella M. Schwartz; Eui-Cheol Shin; Andrew G. Soerens; Daniela S. Thommen; Vaiva Vezys; João P. B. Viola; Bruce D. Walker; Tania H. Watts; Casey T. Weaver; E. John Wherry; Hai-Hui Xue; Ben Youngblood; Rafi Ahmed
Unconventional T cell development in the human postnatal thymus
JOURNAL OF IMMUNOLOGY
IF3.4
2025-11-010
PRE
Perriman, Louis; Tavakolinia, Naeimeh; Jalali, Sedigheh; Li, Shuo; Hickey, Peter F.; Amann-Zalcenstein, Daniela; Ho, William Wing Ho; Baldwin, Tracey M.; Piers, Adam T.; Konstantinov, Igor E.; Anderson, Jeremy; Stanley, Edouard G.; Licciardi, Paul V.; Kannourakis, George; Naik, Shalin H.; Koay, Hui-Fern; Mackay, Laura K.; Berzins, Stuart P.; Pellicci, Daniel G.
Transcriptional regulator SATB1 limits CD8+ T cell population expansion and effector differentiation in chronic infection and cancer

转录因子SATB1限制CD8+ T细胞群体扩增和效应分化，这在慢性感染和癌症中尤为明显。

Nature Immunology
IF27.6
2025-10-270
PRE
Leonie Heyden; Lisa Rausch; Michael H. Shannon; Lachlan Dryburgh; Marcela L. Moreira; Aleksej Frolov; Christina M. Scheffler; Marit J. van Elsas; Junming Tong; Olivia Hidajat; Sharanya K. M. Wijesinghe; Sining Li; Helena Horvatic; Nhat Truong Huynh-Anh; Catarina Gago da Graça; Carlson Tsui; Maren Köhne; Daniel Sommer; F. Thomas Wunderlich; Bianca von Scheidt; Simone L. Park; Laura K. Mackay; Daniel T. Utzschneider; Jan Schröder; Stephen J. Turner; Phillip K. Darcy; Marc D. Beyer; Zeinab Abdullah; Axel Kallies
Parity and lactation induce T cell mediated breast cancer protection

同源性和哺乳诱导T细胞介导的乳腺癌保护作用

Nature
IF48.5
2025-10-200
PRE
Balaji Virassamy; Franco Caramia; Peter Savas; Michael A. Harris; Jia-Wern Pan; Jianan Wang; Emmaline Brown; Megan M. R. O’Malley; Courtney T. van Geelen; Michael Hun; Thomas N. Burn; Sneha Sant; Jamieson D. Ballan; Jasmine Kay; Luis E. Lara Gonzalez; Kylie Clarke; Han Xian Aw Yeang; Rejhan Idrizi; Metta Jana; Damon J. Challice; Roberto Salgado; Heather Thorne; Cathie Poliness; Sophie Nightingale; Soo-Hwang Teo; Terence P. Speed; Jane Visvader; Paul J. Neeson; Phillip K. Darcy; Laura K. Mackay; Sherene Loi
PD-1 is requisite for skin TRM cell formation and specification by TGFβ

PD-1是tgf β 形成和规范皮肤TRM细胞的必要条件

Nature Immunology
IF27.6
2025-07-290
OA
K. Sanjana P. Devi; Eric Wang; Abhinav Jaiswal; Piotr Konieczny; Tae-Gyun Kim; Christopher J. Nirschl; Akanksha Verma; Yong Liu; Julia Milczanowski; Susan N. Christo; Luke C. Gandolfo; Karyn Haitz; Trupti D. Vardam; Pinru Wu; Sandra L. King; Sze-Wah Tse; Komal Pradhan; Xiaodong Jiang; Tian Tian; Robert C. Fuhlbrigge; Chrysalyne D. Schmults; Rachael A. Clark; Thomas S. Kupper; Gordon J. Freeman; Laura K. Mackay; Shruti Naik; Evan W. Newell; Olivier Elemento; Mayte Suarez-Farinas; Niroshana Anandasabapathy
Rewiring endogenous genes in CAR T cells for tumour-restricted payload delivery

在CAR T细胞中重新连接内源性基因以进行肿瘤限制性有效载荷递送

Nature
IF48.5
2025-07-020
OA
Amanda X. Y. Chen; Kah Min Yap; Joelle S. Kim; Kevin Sek; Yu-Kuan Huang; Phoebe A. Dunbar; Volker Wiebking; Jesse D. Armitage; Isabelle Munoz; Kirsten L. Todd; Emily B. Derrick; Dat Nguyen; Junming Tong; Cheok Weng Chan; Thang X. Hoang; Katherine M. Audsley; Marit J. van Elsas; Jim Middelburg; Joel N. Lee; Maria N. de Menezes; Thomas J. Cole; Jasmine Li; Christina Scheffler; Andrew M. Scott; Laura K. Mackay; Jason Waithman; Jane Oliaro; Simon J. Harrison; Ian A. Parish; Junyun Lai; Matthew H. Porteus; Imran G. House; Phillip K. Darcy; Paul A. Beavis
Splenic fibroblastic reticular cells orchestrate dendritic cell maturation and facilitate CD8 + T cell priming and protective memory

脾脏纤维母细胞样网状细胞调控树突状细胞成熟，并促进CD8(+) T细胞的初始激活和保护性记忆。

Science Advances
IF12.5
2025-01-010
OA
Yannick O. Alexandre; Nikita Potemkin; Dominik Schienstock; Baptiste Duchamp; Annika Poch; Susan N. Christo; Shihan Li; Lei Qin; Lynette Beattie; Daniel T. Utzschneider; Masahiro Ono; Jan Schröder; Laura K. Mackay; Scott N. Mueller

研究方向

暂未获取到该数据
S
Scott N. Mueller
H 指数:56论文数:191被引数:1.4万
S
Susan N. Christo
H 指数:26论文数:50被引数:2,989
S
Simone L. Park
H 指数:20论文数:46被引数:2,742
W
William R. Heath
H 指数:101论文数:331被引数:4.1万
T
Thomas Gebhardt
H 指数:43论文数:156被引数:1.1万
M
Maximilien Evrard
H 指数:29论文数:65被引数:5,905
H
Hui‐Fern Koay
H 指数:23论文数:74被引数:4,946
Y
Yannick O. Alexandre
H 指数:22论文数:47被引数:2,148
T
Thomas N. Burn
H 指数:12论文数:35被引数:907
A
Axel Kallies
H 指数:77论文数:319被引数:2.4万