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P

Pascal Meier

The Institute of Cancer Research
H指数:54
被引数:1.8万

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IAP antagonist tolinapant (ASTX660) in combination with pembrolizumab in advanced solid tumors: a phase I trial

IAP拮抗剂托利那潘特（ASTX660）联合帕博利珠单抗治疗晚期实体瘤：一项I期临床试验

Nature Communications
IF15.7
2026-09-300
OA
Crescens Tiu; Wing Yau; Tencho Tenev; Daniel Lionarons; Ching Leung; Victoria Sanchez-Perez; Giovanni Codacci-Pisanelli; Xiaoran Lai; Anna Zachariou; Aasia Hussain; Toby Prout; Mona Parmar; Bindu Baikady; Maria Goicoechea; Scott Layzell; Naomi Guppy; Ioannis Roxanis; Thomas Lund; Diego Carlos Dos Reis; Camila Pereira Almeida; Tatiany Luiza Silveira; Ana Ferreira; Bora Gurel; Claudia Bertan; Mateus Crespo; Penny Flohr; Ann-Marie Baker; Trevor Graham; Luis Zapata; Claudio Salas; Soham Mandal; Alan Dunlop; Martin Sims; George Ward; Tomoko Smyth; Simone Jueliger; Matthew Davis; Ilya Potapov; Aram Oganesian; Danna Chan; Mattias Leino; Subham Basu; Andre Samson; James M. Murphy; Nina Tunariu; Edward W. Johnston; Alistair Ring; Nick Turner; Andrew N. J. Tutt; Amanda Swain; Anna Minchom; Adam Sharp; Alec Paschalis; Udai Banerji; Johann de Bono; Bristi Basu; Christina Yap; Syed Haider; Juanita Lopez; Pascal Meier
Author Correction: Palbociclib and dsRNA sensor co-operate to enhance anti-cancer effects through ER stress and modulation of immune evasion

作者更正: Palbociclib和dsRNA传感器合作通过ER应激和调节免疫逃避来增强抗癌作用

Nature Communications
IF15.7
2025-07-150
OAAI
Victoria Roulstone; Joan Kyula-Currie; James Wright; Emmanuel C. Patin; Isaac Dean; Lu Yu; Aida Barreiro-Alonso; Miriam Melake; Jyoti Choudhary; Richard Elliott; Christopher J. Lord; David Mansfield; Nik Matthews; Ritika Chauhan; Victoria Jennings; Charleen Chan Wah Hak; Holly Baldock; Francesca Butera; Elizabeth Appleton; Pablo Nenclares; Malin Pedersen; Shane Foo; Amarin Wongariyapak; Antonio Rullan; Tencho Tenev; Pascal Meier; Richard Vile; Hardev Pandha; Alan Melcher; Martin McLaughlin; Kevin J. Harrington
The PARP inhibitor talazoparib synergizes with reovirus to induce cancer killing and tumour control in vivo in mouse models

PARP抑制剂talazoparib与呼肠孤病毒协同作用，在小鼠模型中体内诱导癌症杀伤和肿瘤控制

Nature Communications
IF15.7
2025-07-080
OAAI
Joan Kyula-Currie; Victoria Roulstone; James Wright; Francesca Butera; Arnaud Legrand; Richard Elliott; Martin McLaughlin; Galabina Bozhanova; Dragomir Krastev; Stephen Pettitt; Tencho Tenev; Magnus Dillon; Shane Foo; Emmanuel C. Patin; Victoria Jennings; Charleen Chan Wah Hak; Elizabeth Appleton; Amarin Wongariyapak; Malin Pedersen; Antonio Rullan; Jyoti Choudhary; Chris Bakal; Pascal Meier; Christopher J. Lord; Alan Melcher; Kevin J. Harrington
Palbociclib and dsRNA sensor co-operate to enhance anti-cancer effects through ER stress and modulation of immune evasion
Nature Communications
IF15.7
2025-05-250
OAAI
Victoria Roulstone; Joan Kyula-Currie; James Wright; Emmanuel C. Patin; Isaac Dean; Lu Yu; Aida Barreiro-Alonso; Miriam Melake; Jyoti Choudhary; Richard Elliott; Christopher J. Lord; David Mansfield; Nik Matthews; Ritika Chauhan; Victoria Jennings; Charleen Chan Wah Hak; Holly Baldock; Francesca Butera; Elizabeth Appleton; Pablo Nenclares; Malin Pedersen; Shane Foo; Amarin Wongariyapak; Antonio Rullan; Tencho Tenev; Pascal Meier; Richard Vile; Hardev Pandha; Alan Melcher; Martin McLaughlin; Kevin J. Harrington
RIPK1 is required for ZBP1-driven necroptosis in human cells

RIPK1是ZBP1驱动的坏死性凋亡在人细胞中所需的。

PLOS BIOLOGY
IF7.2
2025-02-210
OA
Amusan, Oluwamuyiwa T.; Wang, Shuqi; Yin, Chaoran; Koehler, Heather S.; Li, Yixun; Tenev, Tencho; Wilson, Rebecca; Bellenie, Benjamin; Zhang, Ting; Wang, Jian; Liu, Chang; Seong, Kim; Poorbaghi, Seyedeh L.; Yates, Joseph; Shen, Yuchen; Upton, Jason W.; Meier, Pascal; Balachandran, Siddharth; Guo, Hongyan
A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death

RIPK1-specific的PROTAC降解剂通过增强免疫原性细胞死亡来实现有效的抗肿瘤活性

IMMUNITY
IF26.3
2024-07-013
OA
Mannion, Jonathan; Gifford, Valentina; Bellenie, Benjamin; Fernando, Winnie; Garcia, Laura Ramos; Wilson, Rebecca; John, Sidonie Wicky; Udainiya, Savita; Patin, Emmanuel C.; Tiu, Crescens; Smith, Angel; Goicoechea, Maria; Craxton, Andrew; Vasconcelos, Nathalia Moraes de; Cheung, Kwai-Ming J.; Cundy, Nicholas J.; Pierrat, Olivier; Brennan, Alfie; Benstead-Hume, Graeme; Roumeliotis, Theodoros I.; Alexander, John; Muirhead, Gareth; Layzell, Scott; Lyu, Wenxin; Roulstone, Victoria; Baldock, Holly; Legrand, Arnaud; Gabel, Florian; Serrano-Aparicio, Natalia; Starling, Chris; Guo, Hongyan; Upton, Jason; Gyrd-Hansen, Mads; Seddon, Benedict; Roxanis, Ioannis; Harrington, Kevin; Haider, Syed; Choudhary, Jyoti S.; Haider, Swen; Tenev, Tencho; Meier, Pascal
Proof-of-concept and preliminary efficacy of triple IAP blockade to maximize immunogenic cell death and induce efficient adaptive immune response: First report on the ASTEROID phase 1 trial
CANCER RESEARCH
IF16.6
2024-04-050
PRE
Tiu, Crescens; Yau, Wing; Sanchez-Perez, Victoria; Codacci-Pisanelli, Giovanni; Leung, Ching; Andrews, Eden S.; Basu, Bristi; Zachariou, Anna; Prout, Toby; Parmar, Mona; Turner, Alison; Lai, Xiaoran; Yin, Zhulin; Swales, Karen E.; Haider, Syed; Lund, Thomas; Dos Reis, Diego C.; Silveira, Tatiany L.; Dunlop, Alan S.; Baker, Ann-Marie; Gurel, Bora; Ferreira, Ana; Bertan, Claudia; Tunariu, Nina; Johnston, Edward W.; Ring, Alistair; Tenev, Tencho; Smyth, Tomoko; Jueliger, Simone; Banerji, Udai; de Bono, Johann S.; Paschalis, Alec; Sharp, Adam; Minchom, Anna; Yap, Christina; Meier, Pascal; Lopez, Juanita S.
Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth (vol 11, 2810, 2020)
NATURE COMMUNICATIONS
IF15.7
2023-09-061
OAAI
Lechertier, Tanguy; Reynolds, Louise E.; Kim, Hyojin; Pedrosa, Ana Rita; Gomez-Escudero, Jesus; Munoz-Felix, Jose M.; Batista, Silvia; Dukinfield, Matthew; Demircioglu, Fevzi; Wong, Ping Pui; Matchett, Kylie P.; Henderson, Neil C.; D'Amico, Gabriela; Parsons, Maddy; Harwood, Catherine; Meier, Pascal; Hodivala-Dilke, Kairbaan M.
Cleavage of cFLIP restrains cell death during viral infection and tissue injury and favors tissue repair
SCIENCE ADVANCES
IF12.5
2023-07-2810
OAAI
Lagunas, Kristel Martinez; Savcigil, Deniz Pinar; Zrilic, Matea; Fraile, Carlos Carvajal; Craxton, Andrew; Self, Emily; Uranga-Murillo, Iratxe; de Miguel, Diego; Arias, Maykel; Willenborg, Sebastian; Piekarek, Michael; Albert, Marie Christine; Nugraha, Kalvin; Lisewski, Ina; Janakova, Erika; Igual, Natalia; Tonnus, Wulf; Hildebrandt, Ximena; Ibrahim, Mohammed; Ballegeer, Marlies; Saelens, Xavier; Kueh, Andrew; Meier, Pascal; Linkermann, Andreas; Pardo, Julian; Eming, Sabine; Walczak, Henning; MacFarlane, Marion; Peltzer, Nieves; Annibaldi, Alessandro
Apoptotic cell death in disease-Current understanding of the NCCD 2023

疾病中的凋亡细胞死亡-对NCCD 2023的当前理解

CELL DEATH AND DIFFERENTIATION
IF15.4
2023-04-26143
OAAI
Vitale, Ilio; Pietrocola, Federico; Guilbaud, Emma; Aaronson, Stuart A.; Abrams, John M.; Adam, Dieter; Agostini, Massimiliano; Agostinis, Patrizia; Alnemri, Emad S.; Altucci, Lucia; Amelio, Ivano; Andrews, David W.; Aqeilan, Rami, I; Arama, Eli; Baehrecke, Eric H.; Balachandran, Siddharth; Bano, Daniele; Barlev, Nickolai A.; Bartek, Jiri; Bazan, Nicolas G.; Becker, Christoph; Bernassola, Francesca; Bertrand, Mathieu J. M.; Bianchi, Marco E.; Blagosklonny, Mikhail V.; Blander, J. Magarian; Blandino, Giovanni; Blomgren, Klas; Borner, Christoph; Bortner, Carl D.; Bove, Pierluigi; Boya, Patricia; Brenner, Catherine; Broz, Petr; Brunner, Thomas; Damgaard, Rune Busk; Calin, George A.; Campanella, Michelangelo; Candi, Eleonora; Carbone, Michele; Carmona-Gutierrez, Didac; Cecconi, Francesco; Chan, Francis K-M; Chen, Guo-Qiang; Chen, Quan; Chen, Youhai H.; Cheng, Emily H.; Chipuk, Jerry E.; Cidlowski, John A.; Ciechanover, Aaron; Ciliberto, Gennaro; Conrad, Marcus; Cubillos-Ruiz, Juan R.; Czabotar, Peter E.; D'Angiolella, Vincenzo; Daugaard, Mads; Dawson, Ted M.; Dawson, Valina L.; De Maria, Ruggero; De Strooper, Bart; Debatin, Klaus-Michael; Deberardinis, Ralph J.; Degterev, Alexei; Del Sal, Giannino; Deshmukh, Mohanish; Di Virgilio, Francesco; Diederich, Marc; Dixon, Scott J.; Dynlacht, Brian D.; El-Deiry, Wafik S.; Elrod, John W.; Engeland, Kurt; Fimia, Gian Maria; Galassi, Claudia; Ganini, Carlo; Garcia-Saez, Ana J.; Garg, Abhishek D.; Garrido, Carmen; Gavathiotis, Evripidis; Gerlic, Motti; Ghosh, Sourav; Green, Douglas R.; Greene, Lloyd A.; Gronemeyer, Hinrich; Haecker, Georg; Hajnoczky, Gyorgy; Hardwick, J. Marie; Haupt, Ygal; He, Sudan; Heery, David M.; Hengartner, Michael O.; Hetz, Claudio; Hildeman, David A.; Ichijo, Hidenori; Inoue, Satoshi; Jaeaettelae, Marja; Janic, Ana; Joseph, Bertrand; Jost, Philipp J.; Kanneganti, Thirumala-Devi; Karin, Michael; Kashkar, Hamid; Kaufmann, Thomas; Kelly, Gemma L.; Kepp, Oliver; Kimchi, Adi; Kitsis, Richard N.; Klionsky, Daniel J.; Kluck, Ruth; Krysko, Dmitri, V; Kulms, Dagmar; Kumar, Sharad; Lavandero, Sergio; Lavrik, Inna N.; Lemasters, John J.; Liccardi, Gianmaria; Linkermann, Andreas; Lipton, Stuart A.; Lockshin, Richard A.; Lopez-Otin, Carlos; Luedde, Tom; MacFarlane, Marion; Madeo, Frank; Malorni, Walter; Manic, Gwenola; Mantovani, Roberto; Marchi, Saverio; Marine, Jean-Christophe; Martin, Seamus J.; Martinou, Jean-Claude; Mastroberardino, Pier G.; Medema, Jan Paul; Mehlen, Patrick; Meier, Pascal; Melino, Gerry; Melino, Sonia; Miao, Edward A.; Moll, Ute M.; Munoz-Pinedo, Cristina; Murphy, Daniel J.; Niklison-Chirou, Maria Victoria; Novelli, Flavia; Nunez, Gabriel; Oberst, Andrew; Ofengeim, Dimitry; Opferman, Joseph T.; Oren, Moshe; Pagano, Michele; Panaretakis, Theocharis; Pasparakis, Manolis; Penninger, Josef M.; Pentimalli, Francesca; Pereira, David M.; Pervaiz, Shazib; Peter, Marcus E.; Pinton, Paolo; Porta, Giovanni; Prehn, Jochen H. M.; Puthalakath, Hamsa; Rabinovich, Gabriel A.; Rajalingam, Krishnaraj; Ravichandran, Kodi S.; Rehm, Markus; Ricci, Jean-Ehrland; Rizzuto, Rosario; Robinson, Nirmal; Rodrigues, Cecilia M. P.; Rotblat, Barak; Rothlin, Carla, V; Rubinsztein, David C.; Rudel, Thomas; Rufini, Alessandro; Ryan, Kevin M.; Sarosiek, Kristopher A.; Sawa, Akira; Sayan, Emre; Schroder, Kate; Scorrano, Luca; Sesti, Federico; Shao, Feng; Shi, Yufang; Sica, Giuseppe S.; Silke, John; Simon, Hans-Uwe; Sistigu, Antonella; Stephanou, Anastasis; Stockwell, Brent R.; Strapazzon, Flavie; Strasser, Andreas; Sun, Liming; Sun, Erwei; Sun, Qiang; Szabadkai, Gyorgy; Tait, Stephen W. G.; Tang, Daolin; Tavernarakis, Nektarios; Troy, Carol M.; Turk, Boris; Urbano, Nicoletta; Vandenabeele, Peter; Vanden Berghe, Tom; Vander Heiden, Matthew G.; Vanderluit, Jacqueline L.; Verkhratsky, Alexei; Villunger, Andreas; von Karstedt, Silvia; Voss, Anne K.; Vousden, Karen H.; Vucic, Domagoj; Vuri, Daniela; Wagner, Erwin F.; Walczak, Henning; Wallach, David; Wang, Ruoning; Wang, Ying; Weber, Achim; Wood, Will; Yamazaki, Takahiro; Yang, Huang-Tian; Zakeri, Zahra; Zawacka-Pankau, Joanna E.; Zhang, Lin; Zhang, Haibing; Zhivotovsky, Boris; Zhou, Wenzhao; Piacentini, Mauro; Kroemer, Guido; Galluzzi, Lorenzo
Novel biochemical, structural, and systems insights into inflammatory signaling revealed by contextual interaction proteomics

上下文相互作用蛋白质组学揭示的炎症信号的新型生化，结构和系统见解

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2022-09-309
OAAI
Ciuffa, Rodolfo; Uliana, Federico; Mannion, Jonathan; Mehnert, Martin; Tenev, Tencho; Marulli, Cathy; Satanowski, Ari; Keller, Lena Maria Leone; Ramirez, Pilar Natalia Rodilla; Ori, Alessandro; Gstaiger, Matthias; Meier, Pascal; Aebersold, Ruedi
ERG activity is regulated by endothelial FAK coupling with TRIM25/USP9x in vascular patterning
DEVELOPMENT
IF3.6
2022-07-124
OAAI
D'Amico, Gabriela; Fernandez, Isabelle; Gomez-Escudero, Jesus; Kim, Hyojin; Maniati, Eleni; Azman, Muhammad Syahmi; Mardakheh, Faraz K.; Serrels, Bryan; Serrels, Alan; Parsons, Maddy; Squire, Anthony; Birdsey, Graeme M.; Randi, Anna M.; Bolado-Carrancio, Alfonso; Gangeswaran, Rathi; Reynolds, Louise E.; Bodrug, Natalia; Wang, Yaohe; Wang, Jun; Meier, Pascal; Hodivala-Dilke, Kairbaan M.

研究方向

暂未获取到该数据
T
Tencho Tenev
H 指数:38论文数:81被引数:6,664
G
Gianmaria Liccardi
H 指数:18论文数:71被引数:2,304
J
John Silke
H 指数:91论文数:370被引数:3.6万
A
Anna Zachariou
H 指数:21论文数:51被引数:3,301
K
Katiuscia Bianchi
H 指数:24论文数:54被引数:1.2万
R
Rebecca Wilson
H 指数:13论文数:40被引数:1.2万
A
Alessandro Annibaldi
H 指数:22论文数:151被引数:2,109
M
Meike Broemer
H 指数:18论文数:28被引数:2,470
M
Mark Ditzel
H 指数:13论文数:22被引数:1,120
S
Sidonie Wicky John
H 指数:7论文数:17被引数:1,006