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W

William M. Oldham

Harvard Medical School
H指数:33
被引数:5,593

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Lactate transport inhibition therapeutically reprograms fibroblast metabolism in experimental pulmonary fibrosis

乳酸转运抑制在实验性肺纤维化中治疗性重编程成纤维细胞代谢

Science Translational Medicine
IF14.6
2026-05-060
PRE
David R. Ziehr; Fei Li; K. Mark Parnell; Nathan M. Krah; Kevin J. Leahy; Christelle Guillermier; Ce Gao; Sean A. Prell; Niv Vigder; Sergio Poli; Jack Varon; Rebecca M. Baron; Bradley A. Maron; Nancy J. Philp; Lida P. Hariri; Edy Y. Kim; Kevin S. Wei; Matthew L. Steinhauser; Rachel S. Knipe; Jared Rutter; William M. Oldham
Mechano-dependent sorbitol accumulation supports biomolecular condensate

力依赖性的山梨醇积累支持生物分子凝聚体

CELL
IF42.5
2025-01-012
PRE
Torrino, Stephanie; Oldham, William M.; Tejedor, Andres R.; Burgos, Ignacio S.; Nasr, Lara; Rachedi, Nesrine; Fraissard, Keren; Chauvet, Caroline; Sbai, Chaima; O'Hara, Brendan P.; Abelanet, Sophie; Brau, Frederic; Favard, Cyril; Clavel, Stephan; Collepardo-Guevara, Rosana; Espinosa, Jorge R.; Ben-Sahra, Issam; Bertero, Thomas
Leukemia inhibitory factor (LIF) receptor amplifies pathogenic activation of fibroblasts in lung fibrosis
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2024-12-050
OAAI
Nguyen, Hung N.; Jeong, Yunju; Kim, Yunhye; Kamiya, Mari; Kim, Yaunghyun; Athar, Humra; Castaldi, Peter J.; Hersh, Craig P.; Menon, Jaivardhan A.; Wong, Jessie; Chan, Ian; Oldham, William M.; Padera, Robert F.; Sharma, Nirmal S.; Sholl, Lynette M.; Vivero, Marina; Watts, Gerald F. M.; Knipe, Rachel S.; Black, Katharine E.; Hariri, Lida P.; Yun, Jeong H.; Merriam, Louis T.; Yuan, Ke; Kim, Edy Y.; Brenner, Michael B.
Tipping Point Analysis Identifies C-terminal src kinase-Collagen 22 Regulation by Inflammation in the Pathogenesis of Early-Stage Pulmonary Arterial Hypertension

转折点分析确定了炎症在早期肺动脉高压发病机制中对C末端src激酶-胶原22的调控。

CIRCULATION
IF38.6
2024-11-120
PRE
Wertheim, Bradley; Wang, Ruisheng; Arons, Elena; Oldham, William; Alba, George; Bowman, Frederick; Sharma, Nirmal; Haley, Kathleen; Samokhin, Andriy; Padera, Robert; Loscalzo, Joseph; Maron, Brad
Dietary intake and glutamine-serine metabolism control pathologic vascular stiffness
CELL METABOLISM
IF30.9
2024-06-013
PRE
Rachedi, Nesrine S.; Tang, Ying; Tai, Yi-Yin; Zhao, Jingsi; Chauvet, Caroline; Grynblat, Julien; Akoumia, Kouame Kan Firmin; Estephan, Leonard; Torrino, Stephanie; Sbai, Chaima; Ait-Mouffok, Amel; Latoche, Joseph D.; Al Aaraj, Yassmin; Brau, Frederic; Abelanet, Sophie; Clavel, Stephan; Zhang, Yingze; Guillermier, Christelle; Kumar, Naveen V. G.; Tavakoli, Sina; Mercier, Olaf; Risbano, Michael G.; Yao, Zhong-Ke; Yang, Guangli; Ouerfelli, Ouathek; Lewis, Jason S.; Montani, David; Humbert, Marc; Steinhauser, Matthew L.; Anderson, Carolyn J.; Oldham, William M.; Perros, Frederic; Bertero, Thomas; Chan, Stephen Y.
Fatty acid metabolism promotes TRPV4 activity in lung microvascular endothelial cells in pulmonary arterial hypertension
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
IF3.5
2024-03-012
PRE
Philip, Nicolas; Yun, Xin; Pi, Hongyang; Murray, Samuel; Hill, Zack; Fonticella, Jay; Perez, Preston; Zhang, Cissy; Pathmasiri, Wimal; Sumner, Susan; Servinsky, Laura; Jiang, Haiyang; Huetsch, John C.; Oldham, William M.; Visovatti, Scott; Leary, Peter J.; Gharib, Sina A.; Brittain, Evan; Simpson, Catherine E.; Le, Anne; Shimoda, Larissa A.; Suresh, Karthik
Single-cell transcriptomics reveal a hyperacute cytokine and immune checkpoint axis after cardiac arrest in patients with poor neurological outcome

单细胞转录组学揭示了心脏骤停后神经功能不良患者的超急性细胞因子和免疫检查点轴

MED
IF11.8
2023-07-013
OAAI
Tamura, Tomoyoshi; Cheng, Changde; Chen, Wenan; Merriam, Louis T.; Athar, Humra; Kim, Yaunghyun H.; Manandhar, Reshmi; Sheikh, Muhammad Dawood Amir; Pinilla-Vera, Mayra; Varon, Jack; Hou, Peter C.; Lawler, Patrick R.; Oldham, William M.; Seethala, Raghu R.; Tesfaigzi, Yohannes; Weissman, Alexandra J.; Baron, Rebecca M.; Ichinose, Fumito; Berg, Katherine M.; Bohula, Erin A.; Morrow, David A.; Chen, Xiang; Kim, Edy Y.

研究方向

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J
Joseph Loscalzo
H 指数:141论文数:1,006被引数:8.3万
B
Bradley A. Maron
H 指数:52论文数:343被引数:1.1万
R
Rui‐Sheng Wang
H 指数:45论文数:231被引数:8,287
H
Heidi E. Hamm
H 指数:71论文数:334被引数:2.1万
E
Elena Arons
H 指数:22论文数:64被引数:1,913
S
Stephen Y. Chan
H 指数:57论文数:354被引数:1.3万
J
Jane A. Leopold
H 指数:58论文数:303被引数:1.2万
A
Andriy O. Samokhin
H 指数:12论文数:37被引数:715
B
Bradley M. Wertheim
H 指数:13论文数:39被引数:882
A
Aaron B. Waxman
H 指数:57论文数:338被引数:1.1万