Linda G. Griffith - Publications, H-index & Citations

Linda G. Griffith

massachusetts institute of technology

86H指数

412论文数

2.9W被引数

收录论文 161

发表时间

Systems biology framework for the rational design of operational conditions for in vitro/in vivo translation of tissue models 用于组织模型体外/体内翻译的理性设计操作条件的系统生物学框架

Science Advances

IF12.5

2026-09-18

OAAI

Jose L. Cadavid; Nikolaos Meimetis; Tyler Matsuzaki; Erin N. Tevonian; Linda G. Griffith; Douglas A. Lauffenburger

Live-cell transcriptomics with engineered virus-like particles 利用工程病毒样颗粒进行活细胞转录组学

Cell

IF42.5

2026-09-01

OAAI

Mohamad Ali Najia; Anna Le; Jacob Borrajo; Lauren Pruett; FuNien Tsai; Ryan Ogi; Jeremy Y. Huang; Linda G. Griffith; George Q. Daley; Paul C. Blainey

Development of a Synthetic Hydrogel to Foster Microvascularization of an Endometriosis Microphysiological System 开发一种合成水凝胶以促进子宫内膜异位症微生理系统的微血管化

Advanced Healthcare Materials

IF9.6

2026-05-06

OAAI

Lauren Pruett; Laura Bahlmann; Ryan Ogi; Angela Jiao; Priyatanu Roy; Matthew Johnson; David Trumper; Linda Griffith

A vascularized liver microphysiological system captures key features of hepatic insulin resistance and monocyte infiltration 血管化的肝脏微生理系统捕获肝脏胰岛素抵抗和单核细胞浸润的关键特征

Nature Communications

IF15.7

2026-02-03

OAAI

Erin N. Tevonian; Ellen L. Kan; Kairav K. Maniar; Alex J. Wang; Anisha Datta; Roger D. Kamm; Douglas A. Lauffenburger; Linda G. Griffith

A microphysiological model of human MASLD reveals paradoxical response to resmetirom 人MASLD的微生理模型揭示了其对resmetirom的矛盾反应

Communications Biology

IF5.1

2026-01-14

OAAI

Dominick J. Hellen; Jessica Ungerleider; Erin Tevonian; Pierre Sphabmixay; Priyatanu Roy; Nikolaos Meimetis; Federico Presutti; Ashleigh M. Williams; Ryan C. Ogi; Caroline A. Lewis; Jacob Jeppesen; Sixian You; Damien Demozay; Linda G. Griffith

Lyme disease increases risk for uterine conditions and gynepathologies

JOURNAL OF IMMUNOLOGY

IF3.4

2025-11-01

PREAI

Colburn, Paige Hansen; Blacker, Grace; Galloway, Sarah D.; Feng, Qingying; Padmanabham, Prasanna; Lee, Brandon; Bruner-Tran, Kaylon; You, Sixian; Pollack, Beth; Weissman, Irving L.; Griffith, Linda; Sinnott-Armstrong, Nasa; Tal, Michal Caspi

Human mesofluidic intestinal model for studying transport of drug carriers and bacteria through a live mucosal barrier 人源介观流体肠道模型，用于研究药物载体和细菌通过活体黏膜屏障的转运

LAB ON A CHIP

IF5.4

2025-01-01

OAAI

Wang, Chia-Ming; Oberoi, Hardeep S.; Law, Devalina; Li, Yuan; Kassis, Timothy; Griffith, Linda G.; Breault, David T.; Carrier, Rebecca L.

Biology-Inspired Dynamic Microphysiological System Approaches to Revolutionize Basic Research, Healthcare and Animal Welfare 仿生动态微生理系统方法：革新基础研究、医疗保健和动物福利

ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION

IF5.8

2025-01-01

OAAI

Marx, U; Beken, S; Chen, ZZ; Dehne, EM; Doherty, A; Ewart, L; Fitzpatrick, SC; Griffith, LG; Gu, ZZ; Hartung, T; Hickman, J; Ingber, DE; Ishida, S; Jeong, J; Leist, M; Levin, L; Mendrick, DL; Pallocca, G; Platz, S; Raschke, M; Smirnova, L; Tagle, DA; Trapecar, M; van Balkom, BWM; van den Eijnden-van Raaij, J; van der Meer, A; Roth, A

Deep and dynamic metabolic and structural imaging in living tissues

SCIENCE ADVANCES

IF12.5

2024-12-13

OAAI

Liu, Kunzan; Cao, Honghao; Shashaty, Kasey; Yu, Li-Yu; Spitz, Sarah; Pramotton, Francesca Michela; Wan, Zhengpeng; Kan, Ellen L.; Tevonian, Erin N.; Levy, Manuel; Lendaro, Eva; Kamm, Roger D.; Griffith, Linda G.; Wang, Fan; Qiu, Tong; You, Sixian

An immune-competent human gut microphysiological system enables inflammation-modulation by Faecalibacterium prausnitzii

NPJ BIOFILMS AND MICROBIOMES

IF9.2

2024-03-29

OAAI

Zhang, Jianbo; Huang, Yu-Ja; Trapecar, Martin; Wright, Charles; Schneider, Kirsten; Kemmitt, John; Hernandez-Gordillo, Victor; Yoon, Jun Young; Poyet, Mathilde; Alm, Eric J.; Breault, David T.; Trumper, David L.; Griffith, Linda G.

A microfluidic hanging droplet as a programmable platform for mammalian egg vitrification

LAB ON A CHIP

IF5.4

2024-01-01

OAAI

Feng, Haidong; Katsikis, Georgios; Napier, India D.; Du, Gong; Lim, Josh; Doyle, Joseph O.; Manalis, Scott R.; Griffith, Linda G.

Report of the Assay Guidance Workshop on 3-Dimensional Tissue Models for Antiviral Drug Development

JOURNAL OF INFECTIOUS DISEASES

IF4.5

2023-09-05

OAAI

Jordan, Robert; Ford-Scheimer, Stephanie L.; Alarcon, Rodolfo M.; Atala, Anthony; Borenstein, Jeffrey T.; Brimacombe, Kyle R.; Cherry, Sara; Clevers, Hans; Davis, Mindy, I; Funnell, Simon G. P.; Gehrke, Lee; Griffith, Linda G.; Grossman, Abigail C.; Hartung, Thomas; Ingber, Donald E.; Kleinstreuer, Nicole C.; Kuo, Calvin J.; Lee, Emily M.; Mummery, Christine L.; Pickett, Thames E.; Ramani, Sasirekha; Rosado-Olivieri, Edwin A.; Struble, Evi B.; Wan, Zhengpeng; Williams, Mark S.; Hall, Matthew D.; Ferrer, Marc; Markossian, Sarine

Technology Insights Organoid co-culture model of the human endometrium in a fully synthetic extracellular matrix enables the of crosstalk

MED

IF11.8

2023-08-01

OAAI

Gnecco, Juan S.; Brown, Alexander; Buttrey, Kira; Ives, Clara; Goods, Brittany A.; Baugh, Lauren; Hernandez-Gordillo, Victor; Loring, Megan; Isaacson, Keith B.; Griffith, Linda G.

The dynamic clustering of insulin receptor underlies its signaling and is disrupted in insulin resistance 胰岛素受体的动态聚集是其信号传导的基础，并在胰岛素抵抗中被破坏

NATURE COMMUNICATIONS

IF15.7

2022-12-06

OAAI

Dall'Agnese, Alessandra; Platt, Jesse M.; Zheng, Ming M.; Friesen, Max; Dall'Agnese, Giuseppe; Blaise, Alyssa M.; Spinelli, Jessica B.; Henninger, Jonathan E.; Tevonian, Erin N.; Hannett, Nancy M.; Lazaris, Charalampos; Drescher, Hannah K.; Bartsch, Lea M.; Kilgore, Henry R.; Jaenisch, Rudolf; Griffith, Linda G.; Cisse, Ibrahim I.; Jeppesen, Jacob F.; Lee, Tong I.; Young, Richard A.

The nuclear receptor THRB facilitates differentiation of human PSCs into more mature hepatocytes (vol 29, 795, 2022)核受体THRB促进人psc分化为更成熟的肝细胞 (vol 29，795，2022)

CELL STEM CELL

IF20.4

2022-11-01

OAAI

Ma, Haiting; de Zwaan, Esmee; Guo, Yang Eric; Cejas, Paloma; Thiru, Prathapan; van de Bunt, Martijn; Jeppesen, Jacob F.; Syamala, Sudeepa; Dall'Agnese, Alessandra; Abraham, Brian J.; Fu, Dongdong; Garrett-Engele, Carrie; Lee, Tong Ihn; Long, Henry W.; Griffith, Linda G.; Young, Richard A.; Jaenisch, Rudolf

Synthetic extracellular matrices and astrocytes provide a supportive microenvironment for the cultivation and investigation of primary pediatric gliomas

NEURO-ONCOLOGY ADVANCES

IF4.1

2022-04-13

OAAI

Rota, Christopher M.; Brown, Alexander T.; Addleson, Emily; Ives, Clara; Trumper, Ella; Pelton, Kristine; Teh, Wei Pin; Schniederjan, Matthew J.; Castellino, Robert Craig; Buhrlage, Sara; Lauffenburger, Douglas A.; Ligon, Keith L.; Griffith, Linda G.; Segal, Rosalind A.

Engineering Modular 3D Liver Culture Microenvironments In Vitro to Parse the Interplay between Biophysical and Biochemical Microenvironment Cues on Hepatic Phenotypes

ADVANCED NANOBIOMED RESEARCH

IF4.4

2021-11-19

OAAI

Wang, Alex J.; Allen, Allysa; Sofman, Marianna; Sphabmixay, Pierre; Yildiz, Ece; Griffith, Linda G.

Flux-Biased, Energy-Efficient Electromagnetic Micropumps Utilizing Bistable Magnetic Latching and Energy-Storage Springs 利用双稳态磁锁和储能弹簧的磁通偏置，节能电磁微泵

IEEE-ASME TRANSACTIONS ON MECHATRONICS

IF7.3

2021-10-01

PREAI

Bhushan, Brij M.; Yoon, Jun Young; Griffith, Linda G.; Trumper, David L.

High resolution stereolithography fabrication of perfusable scaffolds to enable long-term meso-scale hepatic culture for disease modeling

BIOFABRICATION

IF8

2021-09-21

OAAI

Sphabmixay, Pierre; Raredon, Micha Sam Brickman; Wang, Alex J-S; Lee, Howon; Hammond, Paula T.; Fang, Nicholas X.; Griffith, Linda G.

A microenvironment-inspired synthetic three-dimensional model for pancreatic ductal adenocarcinoma organoids 胰腺导管腺癌类器官的微环境启发合成三维模型

NATURE MATERIALS

IF38.5

2021-09-13

106

OAAI

Below, Christopher R.; Kelly, Joanna; Brown, Alexander; Humphries, Jonathan D.; Hutton, Colin; Xu, Jingshu; Lee, Brian Y.; Cintas, Celia; Zhang, Xiaohong; Hernandez-Gordillo, Victor; Stockdale, Linda; Goldsworthy, Matthew A.; Geraghty, Joe; Foster, Lucy; O'Reilly, Derek A.; Schedding, Barbara; Askari, Janet; Burns, Jessica; Hodson, Nigel; Smith, Duncan L.; Lally, Catherine; Ashton, Garry; Knight, David; Mironov, Aleksandr; Banyard, Antonia; Eble, Johannes A.; Morton, Jennifer P.; Humphries, Martin J.; Griffith, Linda G.; Jorgensen, Claus

研究方向