Francis K.L. Chan - Publications, H-index & Citations

Francis K.L. Chan

Department of Medicine and Therapeutics

128H指数

1.3K论文数

7.1W被引数

收录论文 455

发表时间

Clinical applications of gut microbiome for non-invasive diagnosis of colorectal neoplasia 肠道微生物组在结直肠肿瘤非侵入性诊断中的临床应用

Journal of Gastroenterology

IF5.5

2026-07-30

OAAI

Colin Cui; Haiyun Shi; Yuji Naito; Koji Otani; Francis K. L. Chan

Novel bacterium Enterocloster sp. M3 promotes colorectal tumorigenesis via the production of the carcinogen styrene 新型细菌Enterocloster sp. M3通过产生致癌物苯乙烯促进结直肠肿瘤发生

Gut Microbes

IF11

2026-02-16

OAAI

Yao Zeng; Yao Huang; Silin Ye; Effie Yin Tung Lau; Man Chun Chiu; Linda Fenske; Yuting Sun; Liting Jiang; Jiangying Chen; Yanqing Huang; Tingyu Zhou; Jiawei Lu; Jie Zhou; Shu Zheng; Francis Ka Leung Chan; Jessie Qiaoyi Liang

Towards global healthy longevity: report from the 1st World Longevity Summit in Kyotango, Japan 迈向全球健康长寿：日本京丹后第一届世界长寿峰会报告

npj Aging

IF6

2025-11-18

OAAI

Tomoya Kitani; Satoaki Matoba; Yuji Naito; Steve Horvath; Tamotsu Yoshimori; Francis K. L. Chan; Tomoo Matsuda; Stefania Bandini; Hironori Nakagami; Ryuichi Morishita; Yasushi Nakayama; Hitoshi Yaku

The Mediating Role of Eating Behaviors Between Autistic Symptoms and Dietary Issues Among Chinese Children With Autism 自闭症症状与饮食问题之间饮食行为的中介作用：基于中国自闭症儿童的研究

Journal of Autism and Developmental Disorders

IF2.8

2025-11-17

OAAI

Yuqi Wu; Sandra S. M. Chan; Patrick W. L. Leung; Holly H. L. Lo; Stephy W. S. Ho; Flora Y. M. Mo; Carol S. W. Ho; Caroline K. S. Shea; Qi Su; Ting Fan Leung; Francis K. L. Chan; Siew Chien Ng; Oscar W. H. Wong

Questionnaire Survey on the Current Status of Advanced Therapy for Inflammatory Bowel Disease in Asia 亚洲地区炎症性肠病晚期治疗现状的问卷调查

DIGESTION

IF3.6

2025-11-01

PREAI

Toya, Yosuke; Shiotani, Akiko; Ono, Shoko; Saito, Yutaka; Sugimoto, Mitsushige; Naito, Yuji; Nomura, Sachiyo; Handa, Osamu; Hisamatsu, Tadakazu; Fujishiro, Mitsuhiro; Matsuda, Takahisa; Morita, Yoshinori; Yahagi, Naohisa; Chan, Francis K. L.; Ang, Tiing Leong; Abdullah, Murdani; Tablante, Maria Carla; Prachayakul, Varayu; Li, Baiwen; Jung, Hwoon-Yong; Matsumoto, Takayuki

The Distinctive Clinical Profiles of Children With Autism Suffering From Different Subtypes of Rome IV Functional Gastrointestinal Disorders 自闭症儿童罹患罗马IV功能性胃肠病不同亚型的独特临床特征

AUTISM RESEARCH

IF5.6

2025-11-01

PREAI

Wong, Isaac Ho Wai; Ng, Sze-mai; Lam, Angela Man Wai; Chan, Sandra Sau Man; Ng, Shing-him; Leung, Jet; Lee, Keith Chun Lok; Wong, Arthur Chun Chi; Wu, Yuqi; Chan, Francis Ka Leung; Ng, Siew Chien; Wong, Oscar Wing Ho

The resident gut microbiome modulates the effect of synbiotics on the immunogenicity after SARS-COV-2 vaccination in elderly and diabetes patients 常住肠道微生物组调节合生元对老年和糖尿病患者SARS-COV-2疫苗接种后免疫原性的影响

npj Biofilms and Microbiomes

IF9.2

2025-08-25

OAAI

Lin Zhang; Shilan Wang; Martin C. S. Wong; Chris K. P. Mok; Jessica Y. L. Ching; Joyce W. Y. Mak; Chunke Chen; Bing Huo; Shuai Yan; Chun Pan Cheung; Emily O. L. Chiu; Emily Y. T. Fung; Pui Kuan Cheong; Francis K. L. Chan; Siew C. Ng

The Role of Gut Microbiota in Insomnia: A Systematic Review of Case–Control Studies 肠道微生物群在失眠中的作用：病例对照研究的系统综述

Life 2025, Vol. 15, Page 1086

IF3.4

2025-08-23

PREAI

Yun Wang; Suyi Xie; Sizhe Chen; Chenyu Li; Yeuk Lam Chan; Ngan Yin Chan; Yun Kwok Wing; Francis K. L. Chan; Qi Su; Siew C. Ng

Gastrointestinal health and nutritional strategies in autism spectrum disorder 自闭症谱系障碍中的胃肠道健康与营养策略

Journal of Gastroenterology

IF5.5

2025-06-18

OAAI

Yuqi Wu; Oscar Wing Ho Wong; Sizhe Chen; Siew Chien Ng; Qi Su; Francis Ka Leung Chan

Microbiome mismatches from microbiota transplants lead to persistent off-target metabolic and immunomodulatory effects 微生物组移植导致的微生物组不匹配会引起持续性的非靶向代谢和免疫调节效应。

Cell

IF42.5

2025-06-06

PREAI

Orlando DeLeon; Mora Mocanu; Alan Tan; Ashley M. Sidebottom; Jason Koval; Hugo D. Ceccato; Sarah Kralicek; John J. Colgan; Marissa M. St. George; Joash M. Lake; Michael Cooper; Jingwen Xu; Julia Moore; Qi Su; Zhilu Xu; Siew C. Ng; Francis K.L. Chan; Hein M. Tun; Candace M. Cham; Cambrian Y. Liu; David T. Rubin; Kristina Martinez-Guryn; Eugene B. Chang

Diet outperforms microbial transplant to drive microbiome recovery in mice 饮食在推动小鼠肠道微生物群恢复方面优于微生物移植。

NATURE

IF48.5

2025-04-30

PREAI

Kennedy, M. S.; Freiburger, A.; Cooper, M.; Beilsmith, K.; George, M. L. St; Kalski, M.; Cham, C.; Guzzetta, A.; Ng, S. C.; Chan, F. K.; DeLeon, O.; Rubin, D.; Henry, C. S.; Bergelson, J.; Chang, E. B.

Preferred Reporting Items for Microbiotherapy (PRIM) Guidelines Across Medical Disciplines: An International Delphi Consensus

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

IF3.4

2025-03-01

OAAI

Zhang, Faming; Kamm, Michael A.; Wu, Xia; Kao, Dina; Borody, Thomas J.; Chen, Lea Ann; He, Xingxiang; Fischer, Monika; Wong, Sunny H.; Ng, Siew C.; Cui, Bota; Chan, Francis K-L; Nie, Yongzhan; Sood, Ajit; Li, Jingnan; Sun, Yang; Dai, Ishikawa; Chen, Qiyi; Lv, Muhan; Zhang, Zulun; Ianiro, Gianluca; Yang, Yunsheng; Kelly, Colleen R.

Roseburia hominis improves host metabolism in diet-induced obesity 罗氏菌属人种（Roseburia hominis）可改善饮食诱导肥胖宿主的代谢。

GUT MICROBES

IF11

2025-02-20

OAAI

Wenli Huang; Wenyi Zhu; Yu Lin; Francis K. L. Chan; Zhilu Xu; Siew C. Ng

Early-life antibiotic exposure aggravates hepatic steatosis through enhanced endotoxemia and lipotoxic effects driven by gut Parabacteroides 早期抗生素暴露通过增强由肠道Parabacteroides驱动的内毒素血症和脂毒性作用，加剧肝脂肪变性。

MEDCOMM

IF10.7

2025-02-17

OAAI

Zhang, Xi; Chan, Darren Chak Lun; Zhu, Jie; Sin, Daniel Zhen Ye; Peng, Ye; Wong, Matthew Kwok Leong; Zhu, Wenyi; Tsui, Yee; Haqq, Andrea M.; Ting, Joseph Y.; Kozyrskyj, Anita; Chan, Francis Ka Leung; Ng, Siew Chien

Questionnaire Survey on the Diagnosis and Treatments of Eosinophilic Gastrointestinal Diseases in Asia 亚洲地区嗜酸性胃肠道疾病诊断和治疗的问卷调查

DIGESTION

IF3.6

2025-02-13

PREAI

Tsuzuki, Yoshikazu; Shiotani, Akiko; Miyaguchi, Kazuya; Ono, Shouko; Saito, Yutaka; Sugimoto, Mitsushige; Naito, Yuji; Nomura, Sachiyo; Handa, Osamu; Hisamatsu, Tadakazu; Fujishiro, Mitsuhiro; Matsuda, Takahisa; Morita, Yoshinori; Yahagi, Naohisa; Chan, Francis K. L.; Ang, Tiing Leong; Abdullah, Murdani; Tablante, Maria Carla; Prachayakul, Varayu; Li, Baiwen; Jung, Hwoon-Yong; Matsumoto, Hisashi; Shiomi, Rie; Imaeda, Hiroyuki

Long-term use of low-dose aspirin for cancer prevention: A 20-year longitudinal cohort study of 1,506,525 Hong Kong residents

INTERNATIONAL JOURNAL OF CANCER

IF4.7

2025-01-18

OAAI

Lam, Amy; Hao, Ziyu; Yiu, Karen; Chan, Stephen; Chan, Francis; Sung, Joseph; Tsoi, Kelvin

Impacts of COVID-19 pandemic on early life gut microbiome COVID-19疫情对早期生命肠道微生物组的影响

GUT MICROBES

IF11

2024-12-31

OAAI

Lin Zhang; Wenye Xu; Henry Y. H. Meng; Jessica Y. L. Ching; Yingzhi Liu; Shilan Wang; Shuai Yan; Ling Lin; Pui K. Cheong; Ka L. Ip; Ye Peng; Jie Zhu; Chun P. Cheung; Ting F. Leung; Agnes S. Y. Leung; Wing H. Tam; Tak Y. Leung; Paul K. S. Chan; Eugene B. Chang; David T. Rubin; Erika C. Claud; William K. K. Wu; Hein M. Tun; Francis K. L. Chan; Siew C. Ng

The Long-Term Risk of Metachronous Advanced Adenoma Recurrence After Endoscopic Submucosal Dissection for Colorectal Neoplasia: A Propensity-Score Matched Longitudinal Cohort With 5-Year Follow-Up

UNITED EUROPEAN GASTROENTEROLOGY JOURNAL

IF6.7

2024-12-21

OAAI

Dai, Min; Xiao, Xiang; Guo, Cosmos L. T.; Lui, Rashid N.; Yip, Hon Chi; Chu, Simon; Hon, Sok Fei; Ng, Simon S. M.; Chiu, Philip W. Y.; Ng, Siew C.; Chan, Francis K. L.; Lau, Louis H. S.

Variation in the metagenomic analysis of fecal microbiome composition calls for a standardized operating approach

MICROBIOLOGY SPECTRUM

IF3.8

2024-12-05

OAAI

Xu, Zhilu; Yeoh, Yun Kit; Tun, Hein M.; Fei, Na; Zhang, Jingwan; Morrison, Mark; Kamm, Michael A.; Yu, Jun; Chan, Francis Ka Leung; Ng, Siew C.

Fecal Microbiota Transplantation for Sleep Disturbance in Post-acute COVID-19 Syndrome

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY

IF12

2024-12-01

PREAI

Lau, Raphaela I.; Su, Qi; Ching, Jessica Y. L.; Lui, Rashid N.; Chan, Ting Ting; Wong, Marc T. L.; Lau, Louis H. S.; Wing, Yun Kwok; Chan, Rachel N. Y.; Kwok, Hanson Y. H.; Ho, Agnes H. Y.; Tse, Yee Kit; Cheung, Chun Pan; Li, Moses K. T.; Siu, Wan Ying; Liu, Chengyu; Lu, Wenqi; Wang, Yun; Chiu, Emily O. L.; Cheong, Pui Kuan; Chan, Francis K. L.; Ng, Siew C.

研究方向