Clifford P. Brangwynne - Publications, H-index & Citations

Clifford P. Brangwynne

princeton university

60H指数

190论文数

3.1W被引数

收录论文 71

发表时间

Deep learning of functional perturbations from condensate morphology 从凝聚体形态深度学习功能扰动

Cell

IF42.5

2026-06-04

OAAI

Anita Donlic; Troy J. Comi; Sofia A. Quinodoz; Nima Jaberi-Lashkari; Krist Antunes Fernandes; Lifei Jiang; Lennard W. Wiesner; Ai Ing Lim; Clifford P. Brangwynne

Kinase KEY1 controls pyrenoid condensate size throughout the cell cycle by disrupting phase separation interactions 激酶KEY1通过破坏相分离相互作用，调控细胞周期全程中蛋白核凝聚体的大小。

Nature Cell Biology

IF19.1

2026-03-17

OAAI

Shan He; Linnea M. Lemma; Alejandro Martinez-Calvo; Guanhua He; Jessica H. Hennacy; Lianyong Wang; Sabrina L. Ergun; Ashwani K. Rai; Colton Wang; Luke Bunday; Angelo Kayser-Browne; Quan Wang; Clifford P. Brangwynne; Ned S. Wingreen; Martin C. Jonikas

Design of de novo nucleolar surface proteins 从头设计核仁表面蛋白

Biophysical Journal

IF3.1

2025-12-03

PREAI

Amal Narayanan; Clifford P. Brangwynne

Mechanical Regulation And Activity of Nuclear Condensates 核凝胶的机械调控及其活性

Biophysical Journal

IF3.1

2025-10-08

PREAI

Jessica Z. Zhao; Jing Xia; Clifford P. Brangwynne

Chromatin heterogeneity modulates nuclear condensate dynamics and phase behavior 染色质异质性调节核凝聚体的动态和相行为

Nature Communications

IF15.7

2025-07-11

OAAI

Jing Xia; Jessica Z. Zhao; Amy R. Strom; Clifford P. Brangwynne

Mapping and engineering RNA-driven architecture of the multiphase nucleolus RNA驱动的多相核仁结构的映射和工程设计

Nature

IF48.5

2025-07-02

OAAI

Sofia A. Quinodoz; Lifei Jiang; Aya A. Abu-Alfa; Troy J. Comi; Hongbo Zhao; Qiwei Yu; Lennard W. Wiesner; Jordy F. Botello; Anita Donlic; Elizabeth Soehalim; Prashant Bhat; Christiane Zorbas; Ludivine Wacheul; Andrej Košmrlj; Denis L. J. Lafontaine; Sebastian Klinge; Clifford P. Brangwynne

The exchange dynamics of biomolecular condensates 生物分子缩合物的交换动力学

ELIFE

IF0

2024-09-25

OAAI

Zhang, Yaojun; Pyo, Andrew G. T.; Kliegman, Ross; Jiang, Yoyo; Brangwynne, Clifford P.; Stone, Howard A.; Wingreen, Ned S.

Interplay of condensation and chromatin binding underlies BRD4 targeting

MOLECULAR BIOLOGY OF THE CELL

IF2.7

2024-06-01

OAAI

Strom, Amy R.; Eeftens, Jorine M.; Polyachenko, Yury; Weaver, Claire J.; Watanabe, Hans -Frederick; Bracha, Dan; Orlovsky, Natalia D.; Jumper, Chanelle C.; Jacobs, William M.; Brangwynne, Clifford P.

Condensate interfaces can accelerate protein aggregation

BIOPHYSICAL JOURNAL

IF3.1

2024-06-01

OAAI

Choi, Chang-Hyun; Lee, Daniel S. W.; Sanders, David W.; Brangwynne, Clifford P.

Interfacial exchange dynamics of biomolecular condensates are highly sensitive to client interactions

JOURNAL OF CHEMICAL PHYSICS

IF3.1

2024-04-09

OAAI

Rana, Ushnish; Wingreen, Ned S.; Brangwynne, Clifford P.; Panagiotopoulos, Athanassios Z.

Evidence for widespread cytoplasmic structuring into mesoscale condensates 广泛的细胞质结构形成中尺度凝聚物的证据

NATURE CELL BIOLOGY

IF19.1

2024-02-29

PREAI

Keber, Felix C.; Nguyen, Thao; Mariossi, Andrea; Brangwynne, Clifford P.; Wuhr, Martin

Viscoelasticity and advective flow of RNA underlies nucleolar form and function

MOLECULAR CELL

IF16.6

2023-09-01

OAAI

Riback, Joshua A.; Eeftens, Jorine M.; Lee, Daniel S. W.; Quinodoz, Sofia A.; Donlic, Anita; Orlovsky, Natalia; Wiesner, Lennard; Beckers, Lien; Becker, Lindsay A.; Strom, Amy R.; Rana, Ushnish; Tolbert, Michele; Purse, Byron W.; Kleiner, Ralph; Kriwacki, Richard; Brangwynne, Clifford P.

Poly(GR) interacts with key stress granule factors promoting its assembly into cytoplasmic inclusions

CELL REPORTS

IF6.9

2023-08-01

OAAI

Park, Jinyoung; Wu, Yanwei; Shao, Wei; Gendron, Tania F.; van der Spek, Sophie J. F.; Sultanakhmetov, Grigorii; Basu, Avik; Otero, Paula Castellanos; Jones, Caroline J.; Jansen-West, Karen; Daughrity, Lillian M.; Phanse, Sadhna; del Rosso, Giulia; Tong, Jimei; Castanedes-Casey, Monica; Jiang, Lulu; Libera, Jenna; Oskarsson, Bjorn; Dickson, Dennis W.; Sanders, David W.; Brangwynne, Clifford P.; Emili, Andrew; Wolozin, Benjamin; Petrucelli, Leonard; Zhang, Yong-Jie

Intrinsically disordered regions of the ARID1A/B tumor suppressors encode an interaction network within biomolecular condensates that directs mSWI/SNF chromatin remodeler complex activity

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Patil, Ajinkya; Strom, Amy R.; Collings, Clayton K.; Paulo, Joao A.; Wauer, Tobias; Sankar, Akshay; St Laurent, Jessica D.; Cervantes, Kasey S.; Gygi, Steven P.; Brangwynne, Clifford P.; Kadoch, Cigall

Size distributions of intracellular condensates reflect competition between coalescence and nucleation

NATURE PHYSICS

IF18.4

2023-02-02

OAAI

Lee, Daniel S. W.; Choi, Chang-Hyun; Sanders, David W. W.; Beckers, Lien; Riback, Joshua A. A.; Brangwynne, Clifford P. P.; Wingreen, Ned S. S.

Fingerprinting Small Molecule Modulators of Nucleolar Biophysics

FASEB JOURNAL

IF4.2

2022-05-13

PREAI

Donlic, Anita; Brangwynne, Clifford P.

The mechanobiology of nuclear phase separation

APL BIOENGINEERING

IF4.1

2022-04-28

OAAI

Lee, Daniel S. W.; Strom, Amy R.; Brangwynne, Clifford P.

Compartmentalization of telomeres through DNA-scaffolded phase separation

DEVELOPMENTAL CELL

IF8.7

2022-01-01

OAAI

Jack, Amanda; Kim, Yoonji; Strom, Amy R.; Lee, Daniel S. W.; Williams, Byron; Schaub, Jeffrey M.; Kellogg, Elizabeth H.; Finkelstein, Ilya J.; Ferro, Luke S.; Yildiz, Ahmet; Brangwynne, Clifford P.

Polycomb condensates can promote epigenetic marks but are not required for sustained chromatin compaction

NATURE COMMUNICATIONS

IF15.7

2021-10-07

OAAI

Eeftens, Jorine M.; Kapoor, Manya; Michieletto, Davide; Brangwynne, Clifford P.

Phase separation vs aggregation behavior for model disordered proteins

JOURNAL OF CHEMICAL PHYSICS

IF3.1

2021-09-22

OAAI

Rana, Ushnish; Brangwynne, Clifford P.; Panagiotopoulos, Athanassios Z.

研究方向