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P

Philippe Froguel

Lille University Hospital
H指数:163
被引数:13.1万

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荣誉奖项

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IRF7 signalling in tanycytes controls brain–body–immune response across the ovarian cycle

IRF7信号在促黄体生成素细胞中调控卵巢周期内的脑-体-免疫反应

Nature Metabolism
IF20.8
2026-10-150
PRE
Sreekala Nampoothiri; Daniela Fernandois; Nathalie Journiac; Fabien Delahaye; Yvon Mbouamboua; Florent Sauve; Marie Couralet; Sarah Gallet; Naziha Mroueh; Maria Laura Serradas Aponte; Nathalie Jouy; Rachel Spenle; Ruth Schmidt-Ullrich; Ines Martinez Corral; Virginie Mattot; Carmen Ruiz de Almodovar; Andreas Schlitzer; Philippe Froguel; Claude-Alain Maurage; Pascal Barbry; Paolo Giacobini; Lennart T. Mars; Amelie Bonnefond; Ruben Nogueiras; Markus Schwaninger; Vincent Prevot
Epigenetic landscapes in human pancreatic islets reveal distinct drivers for adaptation to age and type 2 diabetes

表观遗传景观在人类胰腺胰岛中揭示了对年龄和2型糖尿病适应性转变的不同驱动因素

Nature Communications
IF15.7
2026-06-030
OAAI
Lucas Maurin; Lorella Marselli; Mathilde Boissel; Vincent Pascat; Mara Suleiman; Emma Henriques; Carmela De Luca; Lijiao Ning; Marie Fourcot; Marta Tesi; Bénédicte Toussaint; Souhila Amanzougarene; Mehdi Derhourhi; Frédérik Oger; Frederic Burdet; Mickael Canouil; Miriam Cnop; Mark Ibberson; Amélie Bonnefond; Piero Marchetti; Philippe Froguel; Amna Khamis
A gut microbiome-kidney-heart axis predictive of future cardiovascular diseases

一个预测未来心血管疾病的肠道微生物组-肾脏-心脏轴

Nature Communications
IF15.7
2026-03-050
OAAI
Kanta Chechi; Rima Chakaroun; Antonis Myridakis; Sofia K. Forslund-Startceva; Sebastien Fromentin; Trine Nielsen; Judith Aron-Wisneswky; Eugeni Belda; Edi Prifti; Pierre Bel Lassen; Gwen Falony; Sara Vieira-Silva; Julien Chilloux; Kazuhiro Sonomura; Lesley Hoyles; Laura Martinez-Gili; Francesco Pallotti; Petros Andrikopoulos; Francesc Puig-Castellví; Romina Pacheco Tapia; Inés Castro-Dionicio; Hugo Roume; Nicolas Pons; Emmanuelle Le Chatelier; Benoit Quinquis; Nathalie Galleron; Magali Berland; Michael T. Olanipekun; Manyi Jia; Angelos Manolias; Bridget Holmes; Solia Adriouch; Matthias Blüher; Luis Pedro Coelho; Kévin Da Silva; Pilar Galan; Boyang Ji; Ana Luisa Neves; Christine Rouault; Joe-Elie Salem; Valentina Tremaroli; Tue H. Hansen; Nadja B. Søndertoft; Christian Lewinter; Helle K. Pedersen; Peter D. Mark; Jens P. Goetze; Lars Køber; Henrik Vestergaard; Torben Hansen; Jean-Daniel Zucker; Taka-Aki Sato; Serge Hercberg; Fredrik Bäckhed; Ivica Letunic; Jean-Michel Oppert; Jens Nielsen; Jeroen Raes; Ioanna Tzoulaki; Abbas Dehghan; Verena Zuber; Emmanuelle Bouzigon; Mark Lathrop; Parminder Raina; Philippe Froguel; Fumihiko Matsuda; Florence Demenais; Dominique Gauguier; Michael Stumvoll; Peer Bork; Oluf Pedersen; S. Dusko Ehrlich; Karine Clément; Marc-Emmanuel Dumas
Partitioned polygenic scores show mechanistic heterogeneity in type 2 diabetes and hypertension comorbidity

分区域多基因评分显示2型糖尿病和高血压合并症的机制异质性

Nature Communications
IF15.7
2026-02-090
OAAI
Vincent Pascat; Liudmila Zudina; Lucas Maurin; Anna Ulrich; Jared G. Maina; Ayse Demirkan; Zhanna Balkhiyarova; Igor Pupko; Yevheniya Sharhorodska; François Pattou; Bart Staels; Marika Kaakinen; Amna Khamis; Amélie Bonnefond; Patricia Munroe; Philippe Froguel; Inga Prokopenko
Prominent mediatory role of gut microbiome in the effect of lifestyle on host metabolic phenotypes

肠道菌群在生活方式对宿主代谢表型影响中的中介作用

GUT MICROBES
IF11
2025-12-310
PRE
Adriouch, Solia; Belda, Eugeni; Swartz, Timothy D.; Forslund, Sofia; Prifti, Edi; Aron-Wisnewsky, Judith; Chakaroun, Rima; Nielsen, Trine; Poitou, Christine; Bel-Lassen, Pierre; Rouault, Christine; Le Roy, Tiphaine; Andrikopoulos, Petros; Chechi, Kanta; Puig-Castellvi, Francesc; Dionicio, Ines Castro; Froguel, Philippe; Holmes, Bridget; Alili, Rohia; Andreelli, Fabrizio; Soula, Hedi; Salem, Joe-Elie; Falony, Gwen; Vieira-Silva, Sara; Raes, Jeroen; Bork, Peer; Stumvoll, Michael; Pedersen, Oluf; Ehrlich, S. Dusko; Dumas, Marc-Emmanuel; Oppert, Jean-Michel; Dao, Maria Carlota; Zucker, Jean-Daniel; Clement, Karine
Exploring the role of readthrough-inducing molecule 2,6-diaminopurine to increase immune response against cancer cells

探索readthrough-inducing molecule 2,6-diaminopurine在增强抗肿瘤细胞免疫反应中的作用

Molecular Therapy
IF12
2025-09-120
OAAI
Carmen Sandoval Pacheco; Alice M. Leroy; Mehdi Derhourhi; Tristan Cardon; Catherine Leroy; Nathalie Jouy; Emmanuelle Com; Blandine Guevel; Roland Bourette; Julie Carrard; Daniela Barros; Belinda Duchêne; Bénédicte Toussaint; Philippe Froguel; Nicolas Jonckheere; Thierry Chassat; Isabelle Van Seuningen; Régis Lavigne; Charles Pineau; Philippe Pierre; Fabrice Soncin; Michel Salzet; Amélie Bonnefond; Fabrice Lejeune
Biallelic pathogenic variants in POMC can cause combined pituitary hormonal deficiency associated with severe obesity

POMC基因的双等位基因致病性变异可导致伴有严重肥胖的垂体联合性激素缺乏症。

EUROPEAN JOURNAL OF ENDOCRINOLOGY
IF5.2
2025-07-010
PRE
Vitellius, Geraldine; Poitou, Christine; Clement, Karine; Petit, Jean Michel; Gatta Cherifi, Blandine; Amanzougarene, Souhila; Derhourhi, Mehdi; Saveanu, Alexandru; Froguel, Philippe; Bonnefond, Amelie; Delemer, Brigitte; Le Collen, Lauriane
Canine genome-wide association study identifies DENND1B as an obesity gene in dogs and humans

犬全基因组关联研究将<i>DENND1B</i>确定为狗和人类中的肥胖基因

Science
IF45.8
2025-03-280
PRE
Natalie J. Wallis; Alyce McClellan; Alexander Mörseburg; Katherine A. Kentistou; Aqfan Jamaluddin; Georgina K. C. Dowsett; Ellen Schofield; Anna Morros-Nuevo; Sadia Saeed; Brian Y. H. Lam; Natasha T. Sumanasekera; Justine Chan; Sambhavi S. Kumar; Rey M. Zhang; Jodie F. Wainwright; Marie Dittmann; Gabriella Lakatos; Kara Rainbow; David Withers; Rebecca Bounds; Marcella Ma; Alexander J. German; Jane Ladlow; David Sargan; Philippe Froguel; I. Sadaf Farooqi; Ken K. Ong; Giles S. H. Yeo; John A. Tadross; John R. B. Perry; Caroline M. Gorvin; Eleanor Raffan
Intrahepatic levels of microbiome-derived hippurate associates with improved metabolic dysfunction-associated steatotic liver disease

微生物组衍生的马尿酸盐的肝内水平与改善的代谢功能障碍相关的脂肪性肝病相关

MOLECULAR METABOLISM
IF6.6
2025-02-010
OAAI
Deslande, Maxime; Puig-Castellvi, Francesc; Castro-Dionicio, Ines; Pacheco-Tapia, Romina; Raverdy, Violeta; Caiazzo, Robert; Lassailly, Guillaume; Leloire, Audrey; Andrikopoulos, Petros; Kahoul, Yasmina; Zaibi, Nawel; Toussaint, Benedicte; Oger, Frederik; Gambardella, Nicolas; Lefebvre, Philippe; Derhourhi, Mehdi; Amanzougarene, Souhila; Staels, Bart; Pattou, Francois; Froguel, Philippe; Bonnefond, Amelie; Dumas, Marc-Emmanuel
PNLIPRP1 Hypermethylation in Exocrine Pancreas Links Type 2 Diabetes and Cholesterol Metabolism
DIABETES
IF7.5
2024-08-131
PRE
Maurin, Lucas; Marselli, Lorella; Boissel, Mathilde; Ning, Lijiao; Boutry, Raphael; Fernandes, Justine; Suleiman, Mara; De Luca, Carmela; Leloire, Audrey; Pascat, Vincent; Toussaint, Benedicte; Amanzougarene, Souhila; Derhourhi, Mehdi; Joerns, Anne; Lenzen, Sigurd; Pattou, Francois; Kerr-Conte, Julie; Canouil, Mickael; Marchetti, Piero; Bonnefond, Amelie; Froguel, Philippe; Khamis, Amna
Functional genetics reveals the contribution of delta opioid receptor to type 2 diabetes and beta-cell function
NATURE COMMUNICATIONS
IF15.7
2024-08-050
OAAI
Meulebrouck, Sarah; Merrheim, Judith; Queniat, Gurvan; Bourouh, Cyril; Derhourhi, Mehdi; Boissel, Mathilde; Yi, Xiaoyan; Badreddine, Alaa; Boutry, Raphael; Leloire, Audrey; Toussaint, Benedicte; Amanzougarene, Souhila; Vaillant, Emmanuel; Durand, Emmanuelle; Loiselle, Helene; Huyvaert, Marlene; Dechaume, Aurelie; Scherrer, Victoria; Marchetti, Piero; Balkau, Beverley; Charpentier, Guillaume; Franc, Sylvia; Marre, Michel; Roussel, Ronan; Scharfmann, Raphael; Cnop, Miriam; Canouil, Mickael; Baron, Morgane; Froguel, Philippe; Bonnefond, Amelie

研究方向

暂未获取到该数据
A
Amélie Bonnefond
H 指数:61论文数:358被引数:1.7万
M
Martine Vaxillaire
H 指数:54论文数:169被引数:1.2万
M
Mark I. McCarthy
H 指数:222论文数:1,509被引数:26.6万
M
Michel Marre
H 指数:93论文数:862被引数:5.0万
O
Oluf Pedersen
H 指数:164论文数:1,264被引数:15.7万
T
Torben Hansen
H 指数:149论文数:1,371被引数:13.2万
C
Cécile Lecœur
H 指数:46论文数:120被引数:2.2万
B
Beverley Balkau
H 指数:102论文数:608被引数:4.1万
M
Meyre, David
H 指数:0论文数:0被引数:7
C
Christian Dina
H 指数:0论文数:1被引数:9