D. Borden Lacy - Publications, H-index & Citations

D. Borden Lacy

vanderbilt university

58H指数

280论文数

1.2W被引数

收录论文 91

发表时间

Mucosal vaccination clears Clostridioides difficile colonization 黏膜疫苗接种清除 *Clostridioides difficile* 定植

Nature

IF48.5

2026-02-18

OAAI

Audrey K. Thomas; F. Christopher Peritore-Galve; Alyssa G. Ehni; Bruno B. C. Lança; Jonathan Coggin; Eric J. Brady; Sandra M. Yoder; Rebecca Shrem; Rubén Cano Rodríguez; Heather K. Kroh; Katherine N. Gibson-Corley; M. Kay Washington; Danyvid Olivares-Villagómez; C. Buddy Creech; Maribeth R. Nicholson; Benjamin W. Spiller; D. Borden Lacy

Nanobodies against Clostridioides difficile CDTb provide a toolkit for potent toxin neutralization and highly sensitive quantitation 抗*Clostridioides difficile* CDTb的纳米抗体提供了一种用于强效毒素中和和高灵敏度定量分析的试剂盒

Journal of Biological Chemistry

IF3.9

2025-12-22

OAAI

Kateryna Nabukhotna; Heather K. Kroh; David M. Anderson; Rubén Cano Rodríguez; John A. Shupe; Maria McGresham; Carla V.T. O’Neale; Rebecca A. Shrem; Brian E. Wadzinski; Kevin L. Schey; Benjamin W. Spiller; D.Borden Lacy

Elucidating the crystal structure of botulinum neurotoxin type A: a personal remembrance 阐明肉毒杆菌神经毒素A型晶体结构：个人回忆

Journal of Neural Transmission

IF4

2025-11-06

OAAI

D. Borden Lacy

The monoclonal antibody AZD5148 confers broad protection against TcdB-diverse Clostridioides difficile strains in mice

PLOS PATHOGENS

IF4.9

2025-11-01

PREAI

Peritore-Galve, F. Christopher; Kroh, Heather K.; Shupe, John A.; Ehni, Alyssa G.; Cano Rodriguez, Ruben; Kordus, Shannon L.; Washington, M. Kay; Knippel, Reece J.; Stanley, Ann Marie; Gamson, Adam; Tkaczyk, Christine; Lacy, D. Borden

Clostridioides difficile toxin B inhibits antigen-specific adaptive immune responses through glucosyltransferase-dependent activity

JOURNAL OF IMMUNOLOGY

IF3.4

2025-11-01

PREAI

Maslanka, Jeffrey R.; Londregan, Jennifer; Denny, Joshua E.; Peritore, F. Christopher; Alameh, Mohamad-Gabriel; Zackular, Joseph P.; Lacy, D. Borden; Abt, Michael C.

Clostridioides difficile toxin A and toxin B inhibit toxin-specific adaptive immune responses through glucosyltransferase-dependent activity *Clostridioides difficile* toxin A和toxin B通过糖基转移酶依赖性活性抑制毒素特异性的适应性免疫应答

Mucosal Immunology

IF7.6

2025-08-16

OAAI

Jeffrey R. Maslanka; Jennifer A. Londregan; Joshua E. Denny; Ellie N. Hulit; Nontokozo V. Mdluli; F. Christopher Peritore-Galve; Md Zahidul Alam; Mohamad-Gabriel Alameh; D. Borden Lacy; Joseph P. Zackular; Michael C. Abt

Species-specific components of the Helicobacter pylori Cag type IV secretion system 幽门螺杆菌Cag IV型分泌系统的种特异性组分

INFECTION AND IMMUNITY

IF2.8

2025-05-13

OAAI

Bryant, Kaeli N.; Frick-Cheng, Arwen E.; Solecki, Lauren E.; Kroh, Heather K.; Mcdonald, W. Hayes; Lacy, D. Borden; McClain, Mark S.; Ohi, Melanie D.; Cover, Timothy L.

Multiomic spatial atlas shows deleted in malignant brain tumors 1 (DMBT1) glycoprotein is lost in colonic dysplasia 多组学空间图谱显示，在结肠异型增生中，恶性脑肿瘤1基因缺失的糖蛋白（DMBT1）丢失。

JOURNAL OF PATHOLOGY

IF5.2

2025-03-03

OAAI

Green, Emily H.; Kotrannavar, Subhag R.; Rutherford, Megan E.; Lunnemann, Hannah M.; Kaur, Harsimran; Heiser, Cody N.; Ding, Hua; Simmons, Alan J.; Liu, Xiao; Lacy, D. Borden; Washington, M. Kay; Shrubsole, Martha J.; Liu, Qi; Lau, Ken S.; Sears, Cynthia L.; Coffey, Robert J.; Drewes, Julia L.; Markham, Nicholas O.

Purified CDT toxins and a clean deletion within the CDT locus provide novel insights into the contribution of binary toxin in cellular inflammation and Clostridioides difficile infection

PLOS PATHOGENS

IF4.9

2024-09-19

OAAI

Nabukhotna, Kateryna; Kordus, Shannon L.; Shupe, John A.; Cano Rodriguez, Ruben; Smith, Anna; Bohannon, Julia K.; Washington, M. Kay; Lacy, D. Borden

Deleted in malignant brain tumors 1 (DMBT1) glycoprotein is lost in colonic dysplasia

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Green, Emily H.; Kotrannavar, Subhag R.; Rutherford, Megan E.; Kaur, Harsimran; Lunnemann, Hannah M.; Heiser, Cody N.; Wu, Shaoguang; Ding, Hua; Simmons, J. Alan; Liu, Xiao; Lacy, D. Borden; Shrubsole, Martha J.; Liu, Qi; Lau, Ken S.; Sears, Cynthia L.; Coffey, Robert J.; Drewes, Julia L.; Markham, Nicholas O.

Nectin-3 and shed forms of CSPG4 can serve as epithelial cell receptors for Clostridioides difficile TcdB

MBIO

IF4.7

2023-10-31

OAAI

Childress, Kevin O.; Cencer, Caroline S.; Tyska, Matthew J.; Lacy, D. Borden

Nonsteroidal anti-inflammatory drugs sensitize epithelial cells to Clostridioides difficile toxin-mediated mitochondrial damage 非甾体类抗炎药使上皮细胞对艰难梭菌毒素介导的线粒体损伤敏感

SCIENCE ADVANCES

IF12.5

2023-07-21

OAAI

Ocana, Joshua Soto; Bayard, Nile U.; Hart, Jessica L.; Thomas, Audrey K.; Furth, Emma E.; Lacy, D. Borden; Aronoff, David M.; Zackular, Joseph P.

Increased intestinal permeability and downregulation of absorptive ion transporters Nhe3, Dra, and Sglt1 contribute to diarrhea during Clostridioides difficile infection

GUT MICROBES

IF11

2023-06-23

OAAI

Peritore-Galve, F. Christopher; Kaji, Izumi; Smith, Anna; Walker, Lauren M.; Shupe, John A.; Washington, M. Kay; Algood, Holly M. Scott; Dudeja, Pradeep K.; Goldenring, James R.; Lacy, D. Borden

Cecum axis (CecAx) preservation reveals physiological and pathological gradients in mouse gastrointestinal epithelium

GUT MICROBES

IF11

2023-03-05

OAAI

Lunnemann, Hannah M.; Shealy, Nicolas G.; Reyzer, Michelle L.; Shupe, John A.; Green, Emily H.; Siddiqi, Uswah; Lacy, D. Borden; Byndloss, Mariana X.; Markham, Nicholas O.

Paeniclostridium sordellii uterine infection is dependent on the estrous cycle

PLOS PATHOGENS

IF4.9

2022-11-21

OAAI

Bernard, Sarah C.; Washington, M. Kay; Lacy, D. Borden

Molecular architecture of bacterial type IV secretion systems

PLOS PATHOGENS

IF4.9

2022-08-11

OAAI

Sheedlo, Michael J.; Ohi, Melanie D.; Lacy, D. Borden; Cover, Timothy L.

Strain Variation in Clostridioides difficile Cytotoxicity Associated with Genomic Variation at Both Pathogenic and Nonpathogenic Loci

MSPHERE

IF3.1

2022-06-29

OAAI

Saund, Katie; Pirani, Ali; Lacy, D. Borden; Hanna, Philip C.; Snitkin, Evan

Glucosyltransferase-dependent and independent effects of Clostridioides difficile toxins during infection

PLOS PATHOGENS

IF4.9

2022-02-17

OAAI

Peritore-Galve, F. Christopher; Shupe, John A.; Cave, Rory J.; Childress, Kevin O.; Washington, M. Kay; Kuehne, Sarah A.; Lacy, D. Borden

Clostridioides difficile toxins: mechanisms of action and antitoxin therapeutics

NATURE REVIEWS MICROBIOLOGY

IF103.3

2021-11-26

OAAI

Kordus, Shannon L.; Thomas, Audrey K.; Lacy, D. Borden

Clostridioides difficile infection induces a rapid influx of bile acids into the gut during colonization of the host

CELL REPORTS

IF6.9

2021-09-01

OAAI

Wexler, Aaron G.; Guiberson, Emma R.; Beavers, William N.; Shupe, John A.; Washington, M. Kay; Lacy, D. Borden; Caprioli, Richard M.; Spraggins, Jeffrey M.; Skaar, Eric P.

研究方向