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L

Luc Friboulet

Université Paris-Saclay
H指数:42
被引数:9,984

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Decoding drug-tolerant persister states in cancer: insights from single-cell, spatial, and computational approaches

解码癌症中药物耐受的持久性状态：单细胞、空间和计算方法的见解

npj Precision Oncology
IF8
2026-09-220
OAAI
Naomi Kaste Mfonfu; Floriane Brayé; Mariana Quiroga Londoño; Hanaé Benamira Carrié; Gleb Simanov; Barbara Luisa Soares; Yasmine Adimi; Théo Perochon; Matteo Cesaroni; Christophe Marcireau; Andrey Yurchenko; Galina Boldina; Sergey Nikolaev; Luc Friboulet
Outcomes of patients treated by FGFR inhibitors according to alteration types: an agnostic monocentric retrospective cohort

FGFR抑制剂治疗患者的结局与变异类型的关系：一项无偏倚的单中心回顾性队列研究

European Journal of Cancer
IF7.1
2026-06-190
PRE
Cedric Pobel; Hassan Badreddine; Cristina Smolenschi; Alice Boileve; Michel Ducreux; Luc Friboulet; Rastislav Bahledal; Anas Gazzah; Kristi Beshiri; Marie Porte; Imen Ben-Ammar; Marie-Anne Audisio; Kaissa Ouali; Mohamed Bani; Yohann Loriot; Damien Vasseur; Maximilliano Gelli; Christophe Massard; Francesco Facchinetti; Antoine Hollebecque
The novel ALK K1150dup mutation mediates resistance to frontline lorlatinib and retains sensitivity to gilteritinib

ALK K1150dup突变介导对一线lorlatinib的耐药性并保留对gilteritinib的敏感性

npj Precision Oncology
IF8
2026-05-130
OAAI
Mai Nagasaka; Francesco Facchinetti; Ludovic Bigot; Floriane Brayé; Matthew R. Groves; Juvenal Yosa; Anthonie van der Wekken; Mihaela Aldea; Benjamin Besse; David Planchard; Charles Naltet; Ryohei Katayama; Ken André Olaussen; Yohann Loriot; Luc Friboulet
Saturation mutagenesis identifies activating and resistance-inducing FGFR kinase domain mutations

饱和诱变鉴定激活和抗性诱导FGFR激酶结构域突变

Nature Genetics
IF29
2025-12-080
OAAI
Carla Tangermann; Avantika Ghosh; Martin Ziegler; Francesco Facchinetti; Jannis Stappenbeck; Yagmur Oyku Carus Sahin; Marisa Riester; Luise Carmina Viardot; Tobias Zundel; Luc Friboulet; Antoine Hollebecque; José J. Naveja; Angela Wanninger; Maria Elena Hess; Tilman Brummer; Melanie Boerries; Sonja Loges; Yohann Loriot; Anna L. Illert; Sven Diederichs
Comprehensive molecular landscape of anal squamous cell carcinoma: analysis of tissue and liquid biopsies from 1844 patients

肛门鳞状细胞癌的全面分子图谱：1844例患者的组织活检和液体活检分析

npj Precision Oncology
IF8
2025-11-240
OAAI
Cristina Smolenschi; Saumya D. Sisoudiya; Antoine Hollebecque; Smruthy Sivakumar; Meagan Montesion; Victor Euzen; Valérie Boige; Alice Boilève; Marine Valery; Isabelle Sourouille; Arnaud Bayle; Mihaela Aldea; Julieta Elena Rodriguez; Massimiliano Gelli; Filippo Gustavo Dall’Olio; Anthony Tarabay; Thomas Pudlarz; Rastislav Bahleda; Alina Fuerea; Léonor Benhaim; Elena Fernandez de Sevilla; Mohamed Bani; Peggy Dartigues; Simon Pernot; Gautier Boillet; Kristi Beshiri; Christophe Massard; Luc Friboulet; Francesco Facchinetti; Ludovic Lacroix; Etienne Rouleau; Fabrice Barlesi; Michel Ducreux; Antoine Italiano; Radwa Sharaf; Damien Vasseur
Personalized Therapy in a Patient With EGFR- Mutated NSCLC Developing Sequential CCDC6-RET Fusion and BRAF V600E Mutation as Bypass Resistance Mechanisms

EGFR突变的NSCLC患者的个性化治疗发展序贯CCDC6-RET融合和BRAF V600E突变作为旁路耐药机制

JTO CLINICAL AND RESEARCH REPORTS
IF3.5
2025-03-010
OA
Marinello, Arianna; Parisi, Claudia; Vasseur, Damien; Combarel, David; Bihoreau, Juliette; Lavaud, Pernelle; Ezzedine, Remy; Zullo, Lodovica; Friboulet, Luc; Zalcman, Gerard; Italiano, Antoine; Besse, Benjamin; Aldea, Mihaela
A model for decoding resistance in precision oncology: acquired resistance to FGFR inhibitors in cholangiocarcinoma

精准肿瘤学中耐药性解码模型：胆管癌对FGFR抑制剂的获得性耐药

ANNALS OF ONCOLOGY
IF65.4
2024-12-011
OAAI
Goyal, L.; DiToro, D.; Facchinetti, F.; Martin, E. E.; Peng, P.; Baiev, I.; Iyer, R.; Maurer, J.; Reyes, S.; Zhang, K.; Majeed, U.; Berchuck, J. E.; Chen, C. T.; Walmsley, C.; Pinto, C.; Vasseur, D.; Gordan, J. D.; Mody, K.; Borad, M.; Karasic, T.; Damjanov, N.; Danysh, B. P.; Wehrenberg-Klee, E.; Kambadakone, A. R.; Saha, S. K.; Hoffman, I. D.; Nelson, K. J.; Iyer, S.; Qiang, X.; Sun, C.; Wang, H.; Li, L.; Javle, M.; Lin, B.; Harris, W.; Zhu, A. X.; Cleary, J. M.; Flaherty, K. T.; Harris, T.; Shroff, R. T.; Leshchiner, I.; Parida, L.; Kelley, R. K.; Fan, J.; Stone, J. R.; Uboha, N. V.; Hirai, H.; Sootome, H.; Wu, F.; Bensen, D. C.; Hollebecque, A.; Friboulet, L.; Lennerz, J. K.; Getz, G.; Juric, D.
Deciphering resistance mechanisms in cancer: final report of MATCH-R study with a focus on molecular drivers and PDX development

破译癌症的耐药机制: MATCH-R研究的最终报告，重点是分子驱动和PDX的发展

MOLECULAR CANCER
IF33.9
2024-10-040
OAAI
Vasseur, Damien; Bigot, Ludovic; Beshiri, Kristi; Florez-Arango, Juan; Facchinetti, Francesco; Hollebecque, Antoine; Tselikas, Lambros; Aldea, Mihaela; Blanc-Durand, Felix; Gazzah, Anas; Planchard, David; Lacroix, Ludovic; Pata-Merci, Noemie; Nobre, Catline; Da Silva, Alice; Nicotra, Claudio; Ngo-Camus, Maud; Braye, Floriane; Nikolaev, Sergey I.; Michiels, Stefan; Jules-Clement, Gerome; Olaussen, Ken Andre; Andre, Fabrice; Scoazec, Jean-Yves; Barlesi, Fabrice; Ponce, Santiago; Soria, Jean-Charles; Besse, Benjamin; Loriot, Yohann; Friboulet, Luc
NVL-655 Is a Selective and Brain-Penetrant Inhibitor of Diverse ALK-Mutant Oncoproteins, Including Lorlatinib-Resistant Compound Mutations

NVL-655是多种ALK突变癌蛋白的选择性和脑渗透性抑制剂，包括对氯拉替尼耐药的化合物突变

CANCER DISCOVERY
IF33.3
2024-09-133
OAAI
Lin, Jessica J.; Horan, Joshua C.; Tangpeerachaikul, Anupong; Swalduz, Aurelie; Valdivia, Augusto; Johnson, Melissa L.; Besse, Benjamin; Camidge, D. Ross; Fujino, Toshio; Yoda, Satoshi; Nguyen-Phuong, Linh; Mizuta, Hayato; Bigot, Ludovic; Nobre, Catline; Lee, Jii Bum; Yu, Mi Ra; Mente, Scot; Sun, Yuting; Kohl, Nancy E.; Porter, James R.; Shair, Matthew D.; Zhu, Viola W.; Felip, Enriqueta; Cho, Byoung Chul; Friboulet, Luc; Hata, Aaron N.; Pelish, Henry E.; Drilon, Alexander
Understanding and Overcoming Resistance to Selective FGFR Inhibitors across FGFR2-Driven Malignancies

了解和克服FGFR2-Driven恶性肿瘤对选择性FGFR抑制剂的耐药性

CLINICAL CANCER RESEARCH
IF10.2
2024-09-030
OAAI
Facchinetti, Francesco; Loriot, Yohann; Braye, Floriane; Vasseur, Damien; Bahleda, Rastislav; Bigot, Ludovic; Barbe, Remy; Nobre, Catline; Combarel, David; Michiels, Stefan; Italiano, Antoine; Smolenschi, Cristina; Tselikas, Lambros; Scoazec, Jean-Yves; Ponce-Aix, Santiago; Besse, Benjamin; Andre, Fabrice; Olaussen, Ken A.; Hollebecque, Antoine; Friboulet, Luc
Development of Novel Models of Aggressive Variants of Castration-resistant Prostate Cancer

去势抵抗性前列腺癌侵袭性变异体新模型的建立

EUROPEAN UROLOGY ONCOLOGY
IF9.3
2024-06-011
PRE
Bigot, Ludovic; Sabio, Jonathan; Poiraudeau, Loic; Annereau, Maxime; Menssouri, Naoual; Helissey, Carole; Deas, Olivier; Aglave, Marine; Ibrahim, Tony; Pobel, Cedric; Nobre, Catline; Nicotra, Claudio; Ngo-Camus, Maud; Lacroix, Ludovic; Rouleau, Etienne; Tselikas, Lambros; Judde, Jean -Gabriel; Chauchereau, Anne; Bernard-Tessier, Alice; Patrikidou, Anna; Naoun, Natacha; Flippot, Ronan; Colomba, Emeline; Fuerea, Alina; Albiges, Laurence; Lavaud, Pernelle; Massard, Christophe; Friboulet, Luc; Fizazi, Karim; Besse, Benjamin; Scoazec, Jean-Yves; Loriot, Yohann
Genomic landscape of liquid biopsy mutations in TP53 and DNA damage genes in cancer patients

癌症患者中TP53和DNA损伤基因的液体活检突变的基因组景观

NPJ PRECISION ONCOLOGY
IF8
2024-02-263
OA
Vasseur, Damien; Arbab, Ahmadreza; Giudici, Fabiola; Marzac, Christophe; Michiels, Stefan; Tagliamento, Marco; Bayle, Arnaud; Smolenschi, Cristina; Sakkal, Madona; Aldea, Mihaela; Sassi, Hela; Dall'Olio, Filippo Gustavo; Pata-Merci, Noemie; Cotteret, Sophie; Fievet, Alice; Auger, Nathalie; Friboulet, Luc; Facchinetti, Francesco; Geraud, Arthur; Ponce, Santiago; Hollebecque, Antoine; Besse, Benjamin; Micol, Jean Baptiste; Italiano, Antoine; Lacroix, Ludovic; Rouleau, Etienne
Resistance to BRAF inhibition explored through single circulating tumour cell molecular profiling in BRAF-mutant non-small-cell lung cancer

通过单个循环肿瘤细胞分子谱分析探索BRAF突变型非小细胞肺癌对BRAF抑制的耐药机制

BRITISH JOURNAL OF CANCER
IF6.8
2024-01-042
OA
Mezquita, Laura; Oulhen, Marianne; Aberlenc, Agathe; Deloger, Marc; Aldea, Mihaela; Honore, Aurelie; Lecluse, Yann; Howarth, Karen; Friboulet, Luc; Besse, Benjamin; Planchard, David; Farace, Francoise
Unraveling resistance and optimizing treatment through molecular profiling in patients with NSCLC and oncogenic fusions
MOLECULAR CANCER THERAPEUTICS
IF5.5
2023-12-010
PRE
Aldea, Mihaela; Pop, Vlad; Marinello, Arianna; Ivashkin, Andrei; Vasseur, Damien; Gendarme, Sebastien; Tagliamento, Marco; Gazzah, Anas; Remon, Jordi; Ben-Ammar, Imen; Frelaut, Maxime; Abdayem, Pamela; Lavaud, Pernelle; Hollebecque, Antoine; Rouleau, Etienne; Loriot, Yohann; Friboulet, Luc; Nikolaev, Sergey; Italiano, Antoine; Barlesi, Fabrice; Planchard, David; Besse, Benjamin
Alkylating Agent-Induced High Tumor Mutational Burden in Medullary Thyroid Cancer and Response to Immune Checkpoint Inhibitors: Two Case Reports

烷化剂诱导的甲状腺髓样癌的高肿瘤突变负荷和对免疫检查点抑制剂的反应: 两例病例报告

THYROID
IF6.7
2023-11-011
PRE
Moog, Sophie; Lamartina, Livia; Bani, Mohamed-Amine; Al Ghuzlan, Abir; Friboulet, Luc; Italiano, Antoine; Lacroix, Ludovic; Vinay, Sophie Postel; Tselikas, Lambros; Deschamps, Frederic; Bonnet, Baptiste; Pani, Fabiana; Baudin, Eric; Hadoux, Julien

研究方向

暂未获取到该数据
B
Benjamin Besse
H 指数:100论文数:1,844被引数:5.6万
K
Ken A. Olaussen
H 指数:35论文数:252被引数:5,954
Y
Yohann Loriot
H 指数:76论文数:1,129被引数:5.4万
F
Fabrice André
H 指数:148论文数:1,829被引数:10.3万
F
Francesco Facchinetti
H 指数:34论文数:310被引数:3,858
J
Jean‐Charles Soria
H 指数:128论文数:1,612被引数:9.0万
A
Antoine Hollebecque
H 指数:65论文数:987被引数:2.6万
L
Ludovic Bigot
H 指数:12论文数:329被引数:990
S
Stefan Michiels
H 指数:85论文数:1,028被引数:3.1万
D
David Planchard
H 指数:87论文数:989被引数:5.1万