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Blockade of interleukin-6 (IL-6) signaling in dedifferentiated liposarcoma (DDLPS) decreases mouse double minute 2 (MDM2) oncogenicity via alternative splicing 在去分化的脂肪肉瘤（DDLPS）中，阻断白介素-6（IL-6）信号通路可通过选择性剪接降低鼠双微体2（MDM2）的致癌性。 Zewdu, Abeba; Braggio, Danielle; Lopez, Gonzalo; Batte, Kara; Khurshid, Safiya; Costas C. de Faria, Fernanda; Bid, Hemant K.; Koller, David; Casadei, Lucia; Ladner, Katherine J.; Wang, David; Grignol, Valerie; Iwenofu, O. Hans; Chandler, Dawn; Guttridge, Denis C.; Pollock, Raphael E. 分享 收藏
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Muscle inflammation is regulated by NF-KB from multiple cells to control distinct states of wasting in cancer cachexia 肌肉炎症由来自多个细胞的nf-kb调节，以控制癌症恶病质中不同的消耗状态 Pryce, Benjamin R.; Oles, Alexander; Talbert, Erin E.; Romeo, Martin J.; Vaena, Silvia; Sharma, Sudarshana; Spadafora, Victoria; Tolliver, Lauren; Mahvi, David A.; Morgan, Katherine A.; Lancaster, William P.; Beal, Eryn; Koren, Natlie; Watts, Bailey; Overstreet, Morgan; Berto, Stefano; Subramanian, Suganya; Calisir, Kubra; Crawford, Anna; Neelon, Brian; Ostrowski, Michael C.; Zimmers, Teresa A.; Tidball, James G.; Wang, David J.; Guttridge, Denis C. 分享 收藏
NF-κB Regulates Innate Immunity in the Muscle Microenvironment to Control Distinct States of Wasting in Pancreatic Cancer-Induced Cachexia Guttridge, Denis C.; Pryce, Benjamin R.; Oles, Alexander; Talbert, Erin E.; Morgan, Katherine A.; Mahvi, David A.; Ostrowski, Michael C.; Zimmers, Teresa A.; Tidball, James G.; Wang, David J. 分享 收藏
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Optimization of a mouse model of pancreatic cancer to simulate the human phenotypes of metastasis and cachexia 模拟人类转移和恶病质表型的胰腺癌小鼠模型的优化 Spadafora, Victoria; Pryce, Benjamin R.; Oles, Alexander; Talbert, Erin E.; Romeo, Martin; Vaena, Silvia; Berto, Stefano; Ostrowski, Michael C.; Wang, David J.; Guttridge, Denis C. 分享 收藏
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Targeting protein tyrosine phosphatases for CDK6-induced immunotherapy resistance Gao, Xueliang; Wu, Yongxia; Chick, Joel M.; Abbott, Andrea; Jiang, Baishan; Wang, David J.; Comte-Walters, Susana; Johnson, Roger H.; Oberholtzer, Nathaniel; Nishimura, Michael I.; Gygi, Steven P.; Mehta, Anand; Guttridge, Denis C.; Ball, Lauren; Mehrotra, Shikhar; Sicinski, Piotr; Yu, Xue-Zhong; Wang, Haizhen 分享 收藏
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Role for activating transcription factor 3 in stress-induced β-cell apoptosis Hartman, MG; Lu, D; Kim, ML; Kociba, GJ; Shukri, T; Buteau, J; Wang, XZ; Frankel, WL; Guttridge, D; Prentki, M; Grey, ST; Ron, D; Hai, TW 分享 收藏
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Redundant Signaling as the Predominant Mechanism for Resistance to Antibodies Targeting the Type-I Insulin-Like Growth Factor Receptor in Cells Derived from Childhood Sarcoma Shackleford, Terry J.; Hariharan, Seethalakshmi; V. Vaseva, Angelina; Alagoa, Karina; Espinoza, Maricruz; Bid, Hemant K.; Li, Fuyang; Zhong, Haihong; Phelps, Doris A.; Roberts, Ryan D.; Cam, Hakan; London, Cheryl A.; Guttridge, Denis C.; Chen, Yidong; Rao, Manjeet; Shiio, Yuzuru; Houghton, Peter J. 分享 收藏
STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer Lefler, Julia E.; MarElia-Bennett, Catherine B.; Thies, Katie A.; Hildreth, Blake E., III; Sharma, Sudarshana M.; Pitarresi, Jason R.; Han, Lu; Everett, Caroline; Koivisto, Christopher; Cuitino, Maria C.; Timmers, Cynthia; O'Quinn, Elizabeth; Parrish, Melodie; Romeo, Martin J.; Linke, Amanda J.; Hobbs, G. Aaron; Leone, Gustavo; Guttridge, Denis C.; Zimmers, Teresa A.; Lesinski, Gregory B.; Ostrowski, Michael C. 分享 收藏
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Wnt signaling promotes oncogenic transformation by inhibiting c-Myc-induced apoptosis (vol 157, pg 429, 2002) You, Zongbing; Saims, Daniel; Chen, Shaoqiong; Zhang, Zhaocheng; Guttridge, Denis C.; Guan, Kun-liang; MacDougald, Ormond A.; Brown, Anthony M. C.; Evan, Gerard; Kitajewski, Jan; Wang, Cun-Yu 分享 收藏
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