E. Premkumar Reddy - Publications, H-index & Citations

E. Premkumar Reddy

Icahn School of Medicine at Mount Sinai

69H指数

261论文数

2.1W被引数

收录论文 102

发表时间

Master Transcription Factor Reprogramming Unleashes Selective Translation Promoting Castration Resistance and Immune Evasion in Lethal Prostate Cancer

CANCER DISCOVERY

IF33.3

2023-09-07

OAAI

Santasusagna, Sandra; Zhu, Shijia; Jawalagatti, Vijayakumar; Carceles-Cordon, Marc; Ertel, Adam; Garcia-Longarte, Saioa; Song, Won-Min; Fujiwara, Naoto; Li, Peiyao; Mendizabal, Isabel; Petrylak, Daniel P.; Kelly, William Kevin; Reddy, E. Premkumar; Wang, Liguo; Schiewer, Matthew J.; Lujambio, Amaia; Karnes, Jeffrey; Knudsen, Karen E.; Cordon-Cardo, Carlos; Dong, Haidong; Huang, Haojie; Carracedo, Arkaitz; Hoshida, Yujin; Rodriguez-Bravo, Veronica; Domingo-Domenech, Josep

Abrogation of interleukin-3 dependence of myeloid cells by the v-src oncogene requires SH2 and SH3 domains which specify activation of STATs

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-29

OAAI

Chaturvedi, P; Sharma, S; Reddy, EP

The C-terminal domain of B-Myb acts as a positive regulator of transcription and modulates its biological functions

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

OAAI

Oh, IH; Reddy, EP

Germ line transmission of the Cdk4R24C mutation facilitates tumorigenesis and escape from cellular senescence

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

154

OAAI

Rane, SG; Cosenza, SC; Mettus, RV; Reddy, EP

Molecular mechanisms associated with the regulation of apoptosis by the two alternatively spliced products of c-Myb

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Kumar, A; Baker, SJ; Lee, CM; Reddy, EP

Posiphen Reduces the Levels of Huntingtin Protein through Translation Suppression

PHARMACEUTICS

IF5.5

2021-12-07

OAAI

Chen, Xu-Qiao; Barrero, Carlos A.; Vasquez-Del Carpio, Rodrigo; Reddy, E. Premkumar; Fecchio, Chiara; Merali, Salim; Deglincerti, Alessia; Fang, Cheng; Rogers, Jack; Maccecchini, Maria L.

Simultaneous CK2/TNIK/DYRK1 inhibition by 108600 suppresses triple negative breast cancer stem cells and chemotherapy-resistant disease

NATURE COMMUNICATIONS

IF15.7

2021-08-03

OAAI

Sato, Katsutoshi; Padgaonkar, Amol A.; Baker, Stacey J.; Cosenza, Stephen C.; Rechkoblit, Olga; Venkata Subbaiah, D. R. C.; Domingo-Domenech, Josep; Bartkowski, Alison; Port, Elisa R.; Aggarwal, Aneel K.; Ramana Reddy, M. V.; Irie, Hanna Y.; Premkumar Reddy, E.

Novel induction of CD40 expression by tumor cells with RAS/RAF/PI3K pathway inhibition augments response to checkpoint blockade RAS/RAF/PI3K通路抑制肿瘤细胞CD40表达的新诱导增强了对检查点阻断的反应

MOLECULAR CANCER

IF33.9

2021-06-06

OAAI

Yan, Chi; Saleh, Nabil; Yang, Jinming; Nebhan, Caroline A.; Vilgelm, Anna E.; Reddy, E. Premkumar; Roland, Joseph T.; Johnson, Douglas B.; Chen, Sheau-Chiann; Shattuck-Brandt, Rebecca L.; Ayers, Gregory D.; Richmond, Ann

critical interactions between TGF-β signaling/ELF, and E-cadherin/β-catenin mediated tumor suppression (vol 25, pg 1871, 2006)

ONCOGENE

IF7.3

2021-04-19

OAAI

Katuri, V.; Tang, Y.; Li, C.; Jogunoori, W.; Deng, C. -X.; Rashid, A.; Sidawy, A. N.; Evans, S.; Reddy, E. P.; Mishra, B.; Mishra, L.

A Contaminant Impurity, Not Rigosertib, Is a Tubulin Binding Agent

MOLECULAR CELL

IF16.6

2020-07-01

OAAI

Baker, Stacey J.; Cosenza, Stephen C.; Athuluri-Divakar, Saikrishna; Reddy, M. V. Ramana; Vasquez-Del Carpio, Rodrigo; Jain, Rinku; Aggarwal, Aneel K.; Reddy, E. Premkumar

A novel inhibitor of cancer stem cells overcomes chemotherapy resistance of triple negative breast cancers

CANCER RESEARCH

IF16.6

2020-02-15

PREAI

Sato, Katsutoshi; Padgaonkar, Amol; Cosenza, Stephen; Baker, Stacey; Reddy, Ramana; Reddy, Epremkumar; Irie, Hanna Y.

Rigosertib (RIG) modulates MAPK and hematopoiesis signaling and synergizes Azacitidine (AZA) altering viral mimicry pathway in myelodysplastic syndrome (MDS)

CANCER RESEARCH

IF16.6

2019-07-01

PREAI

Melana, Stella M.; Rai, Richa; Navada, Shyamala C.; Odchimar-Reissig, Rosalie; Demakos, Erin P.; Reddy, E. Premkumar; Silverman, Lewis R.

Dual inhibition of FLT3 and Src pathways by ON150030, a type 1 inhibitor, as a novel strategy for relapsed and refractory AML therapy

CANCER RESEARCH

IF16.6

2017-07-01

PREAI

Ghaffari, Helya; Reddy, M. V. Ramana; Cosenza, Stephen C.; del Carpio, Rodrigo Vasques; Reddy, E. Premkumar

Drugging the 'undruggable' cancer targets 给 “不可下药” 的癌症目标下药

NATURE REVIEWS CANCER

IF66.8

2017-06-23

673

OAAI

Dang, Chi V.; Reddy, E. Premkumar; Shokat, Kevan M.; Soucek, Laura

Dual targeting of ARK5 and CDK4 pathways with ON 123300 as a therapeutic strategy for colorectal carcinoma

CANCER RESEARCH

IF16.6

2016-07-15

PREAI

Divakar, Saikrishna A.; Reddy, M. V. Ramana; Cosenza, Stephen C.; Baker, Stacey J.; Purohit, Vinee; Gunda, Venugopal; Singh, Pankaj K.; Reddy, E. Premkumar

Dual Targeting of CDK4 and ARK5 Using a Novel Kinase Inhibitor ON123300 Exerts Potent Anticancer Activity against Multiple Myeloma

CANCER RESEARCH

IF16.6

2016-02-29

OAAI

Perumal, Deepak; Kuo, Pei-Yu; Leshchenko, Violetta V.; Jiang, Zewei; Divakar, Sai Krishna Athaluri; Cho, Hearn Jay; Chari, Ajai; Brody, Joshua; Reddy, M. V. Ramana; Zhang, Weijia; Reddy, E. Premkumar; Jagannath, Sundar; Parekh, Samir

Discovery of 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one (7ao) as a potent selective inhibitor of Polo like kinase 2 (PLK2)

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2016-02-01

OAAI

Reddy, M. V. Ramana; Akula, Balireddy; Jatiani, Shashidhar; Vasquez-Del Carpio, Rodrigo; Billa, Vinay K.; Mallireddigari, Muralidhar R.; Cosenza, Stephen C.; Subbaiah, D. R. C. Venkata; Bharathi, E. Vijaya; Pallela, Venkat R.; Ramkumar, Poornima; Jain, Rinku; Aggarwal, Aneel K.; Reddy, E. Premkumar

JNK-associated Leucine Zipper Protein Functions as a Docking Platform for Polo-like Kinase 1 and Regulation of the Associating Transcription Factor Forkhead Box Protein K1

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2015-12-01

OAAI

Ramkumar, Poornima; Lee, Clement M.; Moradian, Annie; Sweredoski, Michael J.; Hess, Sonja; Sharrocks, Andrew D.; Haines, Dale S.; Reddy, E. Premkumar

The dual CK2/TNIK inhibitor, ON108600 targets cancer stem cells and induces apoptosis of paclitaxel resistant triple-negative breast cancer cells

CANCER RESEARCH

IF16.6

2015-08-01

PREAI

Padgaonkar, Amol; Cosenza, Stephen; Pallela, Venkat; Subbaiah, Venkata D. R. C.; Reddy, M. V. Ramana; Reddy, E. Premkumar