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Adaptive evolution of drug responses to monotherapy ONC201 in PDOX models of pediatric brain tumors ONC201单药疗法在儿童脑肿瘤PDOX模型中的药物反应适应性进化 Chen, Jinnan; Abdallah, Aalaa; Palacios, Milagros Suarez; Zhai, Xin; Hang, Zilu; Jiang, Tongchao; Ciolak, Emily; Hoesley, Aria; Mei, Yiming; Bellis, James; Wadhwani, Nitin; Lenzen, Alicia; Kwon, Jee Young; Neuhauser, Steve; Stearns, Tim; Chuang, Jeff; Jocoy, Emily; Bult, Carol; Teicher, Beverly; Smith, Malcolm; Li, Xiaonan; Du, Yuchen 分享 收藏
The CD123 antibody-drug conjugate pivekimab sunirine exerts profound activity in preclinical models of pediatric acute lymphoblastic leukemia CD123抗体药物偶联物pivekimab sunirine在儿童急性淋巴细胞白血病临床前模型中表现出显著的活性。 Watts, Ben; Smith, Christopher M.; Evans, Kathryn; Gifford, Andrew J.; Mohamed, Sara M. A.; Erickson, Stephen W.; Earley, Eric J.; Neuhauser, Steven; Stearns, Timothy M.; Philip, Vivek M.; Chuang, Jeffrey H.; Zweidler-McKay, Patrick A.; Lakshmikanthan, Sribalaji; Jocoy, Emily L.; Bult, Carol J.; Teicher, Beverly A.; Smith, Malcolm A. 分享 收藏
The novel ATR inhibitor elimusertib is efficacious as monotherapy and in combination with radiation in pdox models of pediatric high-grade glioma 新型ATR抑制剂elimusertib在小儿高级别神经胶质瘤的pdox模型中作为单药治疗和与放射联合治疗有效 Palacios, M. Suarez; Du, Y.; Xiao, S.; Abdallah, A.; Zhai, X.; Ciolak, E.; Huang, Z.; Kalapurakal, J.; Wadhwani, N.; Lenzen, A.; Kwon, J. Y.; Neuhauser, S.; Stearns, T.; Chuang, J.; Jocoy, E. L.; Bult, C.; Teicher, B.; Smith, M. A.; Li, X. N. 分享 收藏
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Multicenter histology image integration and multiscale deep learning for pediatric sarcoma subtype classification Thiesen, Adam H.; Domanskyi, Sergii; Pour, Ali Foroughi; Sheridan, Todd B.; Neuhauser, Steven B.; Stetson, Alyssa; Dannheim, Katelyn; Cameron, Danielle B.; Ahn, Shawn; Wu, Hao; Christison-Lagay, Emily R.; Bult, Carol J.; Chuang, Jeffrey H.; Rubinstein, Jill C. 分享 收藏
A Pan-Cancer Patient-Derived Xenograft Histology Image Repository with Genomic and Pathologic Annotations Enables Deep Learning Analysis White, Brian S.; Woo, Xing Yi; Koc, Soner; Sheridan, Todd; Neuhauser, Steven B.; Wang, Shidan; Evrard, Yvonne A.; Chen, Li; Pour, Ali Foroughi; Landua, John D.; Mashl, R. Jay; Davies, Sherri R.; Fang, Bingliang; Rosa, Maria Gabriela; Evans, Kurt W.; Bailey, Matthew H.; Chen, Yeqing; Xiao, Min; Rubinstein, Jill C.; Sanderson, Brian J.; Lloyd, Michael W.; Domanskyi, Sergii; Dobrolecki, Lacey E.; Fujita, Maihi; Fujimoto, Junya; Xiao, Guanghua; Fields, Ryan C.; Mudd, Jacqueline L.; Xu, Xiaowei; Hollingshead, Melinda G.; Jiwani, Shahanawaz; Acevedo, Saul; Davis-Dusenbery, Brandi N.; Robinson, Peter N.; Moscow, Jeffrey A.; Doroshow, James H.; Mitsiades, Nicholas; Kaochar, Salma; Pan, Chong-xian; Carvajal-Carmona, Luis G.; Welm, Alana L.; Welm, Bryan E.; Govindan, Ramaswamy; Li, Shunqiang; Davies, Michael A.; Roth, Jack A.; Meric-Bernstam, Funda; Xie, Yang; Herlyn, Meenhard; Ding, Li; Lewis, Michael T.; Bult, Carol J.; Dean II, Dennis A.; Chuang, Jeffrey H. 分享 收藏
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Minimum information and guidelines for reporting a multiplexed assay of variant effect Claussnitzer, Melina; Parikh, Victoria N.; Wagner, Alex H.; Arbesfeld, Jeremy A.; Bult, Carol J.; Firth, Helen V.; Muffley, Lara A.; Ba, Alex N. Nguyen; Riehle, Kevin; Roth, Frederick P.; Tabet, Daniel; Bolognesi, Benedetta; Glazer, Andrew M.; Rubin, Alan F. 分享 收藏
In vivo efficacy of anti-B7-H3 antibody-drug conjugate (ADC) ifinatamab deruxtecan (I-DXd; DS-7300): An update from the Pediatric Preclinical In Vivo Testing (PIVOT) Program Gorlick, Richard; Gill, Jonathan; Zhang, Wendong; Mosse, Yael; Maris, John; Groff, David; Smith, Malcolm; Teicher, Beverly; Neuhauser, Steve; Stearns, Tim; Philip, Vivek; Jocoy, Emily; Chuang, Jeff; Bult, Carol J.; Hasegawa, Jun; Qian, Xiaozhong; Houghton, Peter; Kurmasheva, Raushan 分享 收藏
Updates to the Alliance of Genome Resources central infrastructure Aleksander, Suzanne A.; Anagnostopoulos, Anna V.; Antonazzo, Giulia; Arnaboldi, Valerio; Attrill, Helen; Becerra, Andres; Bello, Susan M.; Blodgett, Olin; Bradford, Yvonne M.; Bult, Carol J.; Cain, Scott; Calvi, Brian R.; Carbon, Seth; Chan, Juancarlos; Chen, Wen J.; Cherry, J. Michael; Cho, Jaehyoung; Crosby, Madeline A.; De Pons, Jeffrey L.; D'Eustachio, Peter; Diamantakis, Stavros; Dolan, Mary E.; dos Santos, Gilberto; Dyer, Sarah; Ebert, Dustin; Engel, Stacia R.; Fashena, David; Fisher, Malcolm; Foley, Saoirse; Gibson, Adam C.; Gollapally, Varun R.; Gramates, L. Sian; Grove, Christian A.; Hale, Paul; Harris, Todd; Hayman, G. Thomas; Hu, Yanhui; James-Zorn, Christina; Karimi, Kamran; Karra, Kalpana; Kishore, Ranjana; Kwitek, Anne E.; Laulederkind, Stanley J. F.; Lee, Raymond; Longden, Ian; Luypaert, Manuel; Markarian, Nicholas; Marygold, Steven J.; Matthews, Beverley; McAndrews, Monica S.; Millburn, Gillian; Miyasato, Stuart; Motenko, Howie; Moxon, Sierra; Muller, Hans-Michael; Mungall, Christopher J.; Muruganujan, Anushya; Mushayahama, Tremayne; Nash, Robert S.; Nuin, Paulo; Paddock, Holly; Pells, Troy; Perrimon, Norbert; Pich, Christian; Quinton-Tulloch, Mark; Raciti, Daniela; Ramachandran, Sridhar; Richardson, Joel E.; Gelbart, Susan Russo; Ruzicka, Leyla; Schindelman, Gary; Shaw, David R.; Sherlock, Gavin; Shrivatsav, Ajay; Singer, Amy; Smith, Constance M.; Smith, Cynthia L.; Smith, Jennifer R.; Stein, Lincoln; Sternberg, Paul W.; Tabone, Christopher J.; Thomas, Paul D.; Thorat, Ketaki; Thota, Jyothi; Tomczuk, Monika; Trovisco, Vitor; Tutaj, Marek A.; Urbano, Jose-Maria; Van Auken, Kimberly; Van Slyke, Ceri E.; Vize, Peter D.; Wang, Qinghua; Weng, Shuai; Westerfield, Monte; Wilming, Laurens G.; Wong, Edith D.; Wright, Adam; Yook, Karen; Zhou, Pinglei; Zorn, Aaron; Zytkovicz, Mark 分享 收藏
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The ROR1 antibody-drug conjugate, MK-2140, enhances the efficacy of established drugs in preclinical models of pediatric acute lymphoblastic leukemia Lock, Richard B.; Evans, Kathryn; Watts, Ben; Bowman, Edward P.; Neuhauser, Steven; Stearns, Timothy; Chuang, Jeffrey H.; Phillip, Vivek M.; Jessen, Katti A.; Jocoy, Emily L.; Bult, Carol J.; Teicher, Beverly A.; Smith, Malcolm A. 分享 收藏
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Spatial proteomics of lung adenocarcinoma mouse models with divergent propensities for metastasis Ramkissoon, Paige; Mitchell-Hutchinson, Naomi; Wells, Julie; Maser, Rick; Stodola, Tim; Hoffmann, Brian; Marchini, Anne; Bechtel, Elaine; Doty, Rosalinda; Bult, Carol J. 分享 收藏
Pediatric Preclinical In Vivo Testing (PIVOT) data portal enables access to 15 years of retrospective treatment study data in support of prospective study design Acevedo, Saul E.; Stearns, Tim M.; Webster, Phillip; Philip, Vivek; Lloyd, Michael W.; Srivastava, Anuj; Neuhauser, Steven; Begley, Dale; Krupke, Debbie; Jocoy, Emily L.; Bult, Carol J.; Chuang, Jeffrey H.; Dean, Dennis A. 分享 收藏
An evaluation of patritumab deruxtecan (HER3-DXd, U3-1402) against pediatric PDX models for hepatoblastoma and rhabdomyosarcoma - A report from the NCI PIVOT Program Kurmasheva, Raushan; Houghton, Peter; Del Pozo, Vanessa; Ghilu, Samson; Nakamura, Ryuichi; Fan, Pang-Dian; Jocoy, Emily; Stearns, Tim; Neuhauser, Steve; Chuang, Jeff; Bult, Carol J.; Teicher, Beverly A.; Smith, Malcolm A. 分享 收藏
GenomeMUSter mouse genetic variation service enables multitrait, multipopulation data integration and analysis Ball, Robyn L.; Bogue, Molly A.; Liang, Hongping; Srivastava, Anuj; Ashbrook, David G.; Lamoureux, Anna; Gerring, Matthew W.; Hatoum, Alexander S.; Kim, Matthew J.; He, Hao; Emerson, Jake; Berger, Alexander K.; Walton, David O.; Sheppard, Keith; El Kassaby, Baha; Castellanos, Francisco; Kunde-Ramamoorthy, Govindarajan; Lu, Lu; Bluis, John; Desai, Sejal; Sundberg, Beth A.; Peltz, Gary; Fang, Zhuoqing; Churchill, Gary A.; Williams, Robert W.; Agrawal, Arpana; Bult, Carol J.; Philip, Vivek M.; Chesler, Elissa J. 分享 收藏
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