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D

David K. Chang

wolfson wohl cancer research centre
H指数:75
被引数:4.7万

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Cancer-associated fibroblasts regulate DNA repair in pancreatic cancer through NDRG1-mediated R-loop processing

癌症相关成纤维细胞通过NDRG1介导的R环处理调控胰腺癌的DNA修复

Nature Cell Biology
IF19.1
2026-04-010
PRE
Kozlova, Nina; Cruz, Kayla A.; Ruzette, Antoine A.; Doh, Hanna M.; Willis, Nicholas A.; Hong, Su Min; Gonzalez, Raul S.; Vyas, Monika; Selfors, Laura M.; Dreyer, Stephan; Upstill-Goddard, Rosie; Faia, Kerrie L.; Wenglowsky, Steve; Close, Josh; Beutel, Alica; Jutric, Zeljka; Oliphant, Michael U. J.; Poluben, Larysa; Thapa, Byanjana; Taylor, Martin S.; Mustonen, Venla; Mangalath, Pradeep; Halbrook, Christopher J.; Grossman, Joseph E.; Hwang, Rosa F.; Clohessy, John G.; Ruskamo, Salla; Kursula, Petri; Petrova, Boryana; Kanarek, Naama; Cole, Philip A.; Chang, David K.; Evans, Conor L.; Norrelykke, Simon F.; Scully, Ralph; Muranen, Taru
Clonal evolutionary analysis reveals patterns of malignant transformation of Intraductal Papillary Mucinous Neoplasms of the pancreas

克隆进化分析揭示了胰腺导管内乳头状黏液性肿瘤的恶性转化模式

Nature Communications
IF15.7
2026-03-040
OAAI
Antonio Pea; Xiaotong He; Rosie Upstill-Goddard; Claudio Luchini; Leonor Patricia Schubert Santana; Stephan Dreyer; Fraser Duthie; Nigel B. Jamieson; Colin J. McKay; Euan J. Dickson; Alessandra Pulvirenti; Selma Rebus; Paola Piccoli; Nicola Sperandio; Rita T. Lawlor; Michele Milella; Fieke E. M. Froeling; Roberto Salvia; Aldo Scarpa; Andrew V. Biankin; David C. Wedge; David K. Chang
Jorunnamycin A induces apoptosis in pancreatic ductal adenocarcinoma cells, spheroids, and patient-derived organoids by modulating KRAS-mediated survival pathways

Jorunnamycin A通过调节KRAS介导的存活途径诱导胰腺导管腺癌细胞，球体和患者来源的类器官凋亡

SCIENTIFIC REPORTS
IF3.9
2025-04-030
OAAI
Khine, Hnin Ei Ei; Suriya, Utid; Rungrotmongkol, Thanyada; Chamni, Supakarn; Lu, Yanxi; Benard, Alan; Lan, Bin; Mukhopadhyay, Debabrata; Chang, David; Biankin, Andrew; Schneider-Stock, Regine; Gruetzmann, Robert; Sungthong, Rungroch; Pilarsky, Christian; Chaotham, Chatchai
nSMase2-mediated exosome secretion shapes the tumor microenvironment to immunologically support pancreatic cancer
CANCER RESEARCH
IF16.6
2024-09-150
PRE
Hendley, Audrey M.; Ashe, Sudipta; Urano, Atsushi; Ng, Martin; Phu, Tuan A.; Peng, Xianlu Laura; Luan, Changfei; Finger, Anna-Marie; Jang, Gun Ho; Kerper, Natanya R.; Berrios, David I.; Jin, David; Lee, Jonghyun; Riahi, Irene R.; Gbenedio, Oghenekevwe M.; Chung, Christina; Roose, Jeroen P.; Yeh, Jen Jen; Gallinger, Steven; Biankin, Andrew V.; O'Kane, Grainne M.; Ntranos, Vasilis; Chang, David K.; Dawson, David W.; Kim, Grace E.; Weaver, Valerie M.; Raffai, Robert L.; Hebrok, Matthias
Integrating metabolic profiling of pancreatic juice with transcriptomic analysis of pancreatic cancer tissue identifies distinct clinical subgroups
FRONTIERS IN ONCOLOGY
IF3.3
2024-06-262
OAAI
Pulvirenti, Alessandra; Barbagallo, Marialuisa; Putignano, Anna Rita; Pea, Antonio; Polidori, Rebecca; Upstill-Goddard, Rosie; Cortese, Nina; Kunderfranco, Paolo; Brunelli, Laura; De Simone, Giulia; Pastorelli, Roberta; Spaggiari, Paola; Nappo, Gennaro; Jamieson, Nigel B.; Zerbi, Alessandro; Chang, David K.; Capretti, Giovanni; Marchesi, Federica
JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
IF12.8
2024-03-018
OAAI
Pennel, Kathryn A. F.; Hatthakarnkul, Phimmada; Wood, Colin S.; Lian, Guang-Yu; Al-Badran, Sara S. F.; Quinn, Jean A.; Legrini, Assya; Inthagard, Jitwadee; Alexander, Peter G.; van Wyk, Hester; Kurniawan, Ahmad; Hashmi, Umar; Gillespie, Michael A.; Mills, Megan; Ammar, Aula; Hay, Jennifer; Andersen, Ditte; Nixon, Colin; Rebus, Selma; Chang, David K.; Kelly, Caroline; Harkin, Andrea; Graham, Janet; Church, David; Tomlinson, Ian; Saunders, Mark; Iveson, Tim; Lannagan, Tamsin R. M.; Jackstadt, Rene; Maka, Noori; Horgan, Paul G.; Roxburgh, Campbell S. D.; Sansom, Owen J.; McMillan, Donald C.; Steele, Colin W.; Jamieson, Nigel B.; Park, James H.; Roseweir, Antonia K.; Edwards, Joanne
nSMase2-generated ceramide promotes PDA aggression through exosome reprogramming of the stroma
CANCER RESEARCH
IF16.6
2024-01-160
PRE
Hendley, Audrey M.; Urano, Atsushi; Peng, Xianlu L.; Ashe, Sudipta; Phu, Tuan A.; Ng, Martin; Kerper, Natanya R.; Berrios, David I.; Lee, Jonghyun; Jin, David; Jang, Gun H.; Gbenedio, Oghenekevwe M.; Roose, Jeroen P.; Yeh, Jen J.; Gallinger, Steven; Biankin, Andrew V.; Ntranos, Vasilis; Chang, David K.; Dawson, David W.; Kim, Grace E.; Weaver, Valerie M.; Raffai, Robert L.; Hebrok, Matthias

研究方向

暂未获取到该数据
A
Andrew V. Biankin
H 指数:101论文数:705被引数:6.3万
N
Nigel B. Jamieson
H 指数:73论文数:451被引数:3.3万
S
Stephan B. Dreyer
H 指数:20论文数:124被引数:2,143
P
Peter J. Bailey
H 指数:79论文数:376被引数:4.5万
S
Sean M. Grimmond
H 指数:106论文数:548被引数:7.2万
M
Marina Pajic
H 指数:62论文数:366被引数:4.0万
A
Anthony J. Gill
H 指数:117论文数:1,226被引数:8.2万
N
Neil D. Merrett
H 指数:54论文数:298被引数:2.9万
N
Nicola Waddell
H 指数:81论文数:601被引数:4.9万
F
Fieke E. M. Froeling
H 指数:20论文数:98被引数:3,867