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Mutational signature-based identification of DNA repair deficient gastroesophageal adenocarcinomas for therapeutic targeting (vol 8, 87, 2024) Prosz, Aurel; Sahgal, Pranshu; Huffman, Brandon M.; Sztupinszki, Zsofia; Morris, Clare X.; Chen, David; Borcsok, Judit; Diossy, Miklos; Tisza, Viktoria; Spisak, Sandor; Likasitwatanakul, Pornlada; Rusz, Orsolya; Csabai, Istvan; Cecchini, Michael; Baca, Yasmine; Elliott, Andrew; Enzinger, Peter; Singh, Harshabad; Ubellaker, Jessalyn; Lazaro, Jean-Bernard; Cleary, James M.; Szallasi, Zoltan; Sethi, Nilay S. 分享 收藏
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Mutational signature-based identification of DNA repair deficient gastroesophageal adenocarcinomas for therapeutic targeting Prosz, Aurel; Sahgal, Pranshu; Huffman, Brandon M.; Sztupinszki, Zsofia; Morris, Clare X.; Chen, David; Borcsok, Judit; Diossy, Miklos; Tisza, Viktoria; Spisak, Sandor; Likasitwatanakul, Pornlada; Rusz, Orsolya; Csabai, Istvan; Cecchini, Michael; Baca, Yasmine; Elliot, Andrew; Enzinger, Peter; Singh, Harshabad; Ubellaker, Jessalyn; Lazaro, Jean-Bernard; Cleary, James M.; Szallasi, Zoltan; Sethi, Nilay S. 分享 收藏
Identifying regulators of aberrant stem cell and differentiation activity in colorectal cancer using a dual endogenous reporter system Spisak, Sandor; Chen, David; Likasitwatanakul, Pornlada; Doan, Paul; Li, Zhixin; Bala, Pratyusha; Vizkeleti, Laura; Tisza, Viktoria; De Silva, Pushpamali; Giannakis, Marios; Wolpin, Brian; Qi, Jun; Sethi, Nilay S. 分享 收藏
Nucleotide excision repair deficiency is a targetable therapeutic vulnerability in clear cell renal cell carcinoma Prosz, Aurel; Duan, Haohui; Tisza, Viktoria; Sahgal, Pranshu; Topka, Sabine; Klus, Gregory T.; Boercsoek, Judit; Sztupinszki, Zsofia; Hanlon, Timothy; Diossy, Miklos; Vizkeleti, Laura; Stormoen, Dag Rune; Csabai, Istvan; Pappot, Helle; Vijai, Joseph; Offit, Kenneth; Ried, Thomas; Sethi, Nilay; Mouw, Kent W.; Spisak, Sandor; Pathania, Shailja; Szallasi, Zoltan 分享 收藏
Aberrant cell state plasticity mediated by developmental reprogramming precedes colorectal cancer initiation Bala, Pratyusha; Rennhack, Jonathan P.; Aitymbayev, Daulet; Morris, Clare; Moyer, Sydney M.; Duronio, Gina N.; Doan, Paul; Li, Zhixin; Liang, Xiaoyan; Hornick, Jason L.; Yurgelun, Matthew B.; Hahn, William C.; Sethi, Nilay S. 分享 收藏
Integrated clinical and genomic analysis identifies driver events and molecular evolution of colitis-associated cancers Chatila, Walid K.; Walch, Henry; Hechtman, Jaclyn F.; Moyer, Sydney M.; Sgambati, Valeria; Faleck, David M.; Srivastava, Amitabh; Tang, Laura; Benhamida, Jamal; Ismailgeci, Dorina; Campos, Carl; Wu, Fan; Chang, Qing; Vakiani, Efsevia; de Stanchina, Elisa; Weiser, Martin R.; Widmar, Maria; Yantiss, Rhonda K.; Shah, Manish A.; Bass, Adam J.; Stadler, Zsofia K.; Katz, Lior H.; Mellinghoff, Ingo K.; Sethi, Nilay S.; Schultz, Nikolaus; Ganesh, Karuna; Kelsen, David; Yaeger, Rona 分享 收藏
Development of Combination Strategies for Focal Adhesion Kinase Inhibition in Diffuse Gastric Cancer Peng, Ke; Zhang, Feifei; Wang, Yichen; Sahgal, Pranshu; Li, Tianxia; Zhou, Jin; Liang, Xiaoyan; Zhang, Yanxi; Sethi, Nilay; Liu, Tianshu; Zhang, Haisheng; Bass, Adam J. 分享 收藏
A novel β-catenin/BCL9 complex inhibitor blocks oncogenic Wnt signaling and disrupts cholesterol homeostasis in colorectal cancer Tanton, Helen; Sewastianik, Tomasz; Seo, Hyuk-Soo; Remillard, David; St Pierre, Roodolph; Bala, Pratyusha; Aitymbayev, Daulet; Dennis, Peter; Adler, Keith; Geffken, Ezekiel; Yeoh, Zoe; Vangos, Nicholas; Garbicz, Filip; Scott, David; Sethi, Nilay; Bradner, James; Dhe-Paganon, Sirano; Carrasco, Ruben D. 分享 收藏
YAP1 and PRDM14 converge to promote cell survival and tumorigenesis Kim, Miju; Ly, Seav Huong; Xie, Yingtian; Duronio, Gina N.; Ford-Roshon, Dane; Hwang, Justin H.; Sulahian, Rita; Rennhack, Jonathan P.; So, Jonathan; Gjoerup, Ole; Talamas, Jessica A.; Grandclaudon, Maximilien; Long, Henry W.; Doench, John G.; Sethi, Nilay S.; Giannakis, Marios; Hahn, William C. 分享 收藏
An Enhancer-Driven Stem Cell-Like Program Mediated by SOX9 Blocks Intestinal Differentiation in Colorectal Cancer Liang, Xiaoyan; Duronio, Gina N.; Yang, Yaying; Bala, Pratyusha; Hebbar, Prajna; Spisak, Sandor; Sahgal, Pranshu; Singh, Harshabad; Zhang, Yanxi; Xie, Yingtian; Cejas, Paloma; Long, Henry W.; Bass, Adam J.; Sethi, Nilay S. 分享 收藏
Early TP53 alterations engage environmental exposures to promote gastric premalignancy in an integrative mouse model Sethi, Nilay S.; Kikuchi, Osamu; Duronio, Gina N.; Stachler, Matthew D.; McFarland, James M.; Ferrer-Luna, Ruben; Zhang, Yanxi; Bao, Chunyang; Bronson, Roderick; Patil, Deepa; Sanchez-Vega, Francisco; Liu, Jie-Bin; Sicinska, Ewa; Lazaro, Jean-Bernard; Ligon, Keith L.; Beroukhim, Rameen; Bass, Adam J. 分享 收藏
Precision oncology decision support within the Gastrointestinal Cancer Center at Dana-Farber Cancer Institute (GI TARGET) Keller, Rachel B.; Mazor, Tali; Giannakis, Marios; Nowak, Jonathan; Sholl, Lynette; Aguirre, Andrew; Bass, Adam; Sethi, Nilay; Nagaraja, Ankur; Brais, Lauren; Reilly, Emma; Cerami, Ethan; Wolpin, Brian 分享 收藏
Mutant p53 induces a hypoxia transcriptional program in gastric and esophageal adenocarcinoma Sethi, Nilay; Kikuchi, Osamu; McFarland, James; Zhang, Yanxi; Chung, Max; Kafker, Nicholas; Islam, Mirazul; Lampson, Benjamin; Chakraborty, Abhishek; Kaelin, William G., Jr.; Bass, Adam J. 分享 收藏
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