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T

Taku Kobayashi

kitasato university kitasato institute hospital
H指数:48
被引数:9,489

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工作经历

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荣誉奖项

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Effectiveness, safety, and clinical outcomes of treatment with the oral α4-integrin antagonist carotegrast methyl in patients with active ulcerative colitis: a multicenter observational study (CANAL study)

奥法木单抗（carotegrast methyl）口服α4整合素拮抗剂治疗活动性溃疡性结肠炎的有效性、安全性和临床结局：一项多中心观察性研究（CANAL研究）

Inflammatory Bowel Diseases
IF4.3
2026-09-280
OAAI
Fumihito Hirai, MD, PhD; Katsuyoshi Matsuoka, MD, PhD; Kenji Watanabe, MD, PhD; Ryota Hokari, MD, PhD; Taku Kobayashi, MD, PhD; Masayuki Saruta, MD, PhD; Hiroshi Nakase, MD, PhD; Takayuki Yamamoto, MD, PhD; Mao Matsubayashi, MD, PhD; Ryuichi Okamoto, MD, PhD; Shinichiro Shinzaki, MD, PhD; Makoto Naganuma, MD, PhD; Hitoshi Hongo, MD, PhD; Hirozumi Obata, MD, PhD; Katsuya Endo, MD, PhD; Akihiro Yamada, MD, PhD; Shinya Ashizuka, MD, PhD; Noritaka Takatsu, MD, PhD; Toshiyuki Sakurai, MD, PhD; Tetsuya Ishida, MD, PhD; Jun Kato, MD, PhD; Masayuki Fukata, MD, PhD; Yusuke Takashima, MD; Yoshiyuki Hosoi, BSc; Takahiro Suzuki, MSc; Gakuto Yamazaki, BS; Toshifumi Hibi, MD, PhD; Mamoru Watanabe, MD, PhD; Tadakazu Hisamatsu, MD, PhD
Association Between Bowel Urgency and Intestinal Ultrasound Parameters in Ulcerative Colitis: Insights Into Transmural Inflammation and Symptom Pathophysiology

溃疡性结肠炎中肠道急迫性与肠超声参数的相关性：对肠壁炎症和症状病理生理学的见解

United European Gastroenterology Journal
IF6.7
2026-09-090
OAAI
Kanade Serizawa; Shintaro Sagami; Satoko Umeda; Kunio Asonuma; Moeko Komatsu; Shunsuke Shibui; Masa Maeda; Akira Nogami; Ryo Karashima; Masaru Nakano; Ichiro Maeda; Toshifumi Hibi; Chika Kusano; Taku Kobayashi
Distinct predictive factors for acute severe ulcerative colitis in East Asian and Western populations

东亚和西方人群中急性重度溃疡性结肠炎的不同预测因素

Inflammatory Bowel Diseases
IF4.3
2026-06-050
OAAI
Eun Soo Kim, MD; Dong Hyun Kim, MD; Seong-Jung Kim, MD; Sang Hyoung Park, MD; Hyun Seok Lee, MD; Sung Kook Kim, MD; Hyun Soo Kim, MD; Jun Lee, MD; Kyeong Ok Kim, MD; Byung Ik Jang, MD; Yoo Jin Lee, MD; Eun Mi Song, MD; Dae Sung Kim, MD; Chun-Chi Lin, MD; Joyce Wing Yan Mak, MD; Jing Liu, MD; Qian Cao, MD; Shu-Chen Wei, MD; Wei-Chen Lin, MD; Wen-Hung Hsu, MD; Shintaro Sagami, MD; Taku Kobayashi, MD; Richard G Fernandes, MD; Robert Gilmore, MD; Yoon-Kyo An, MD; Jakob Begun, MD; Katie Rice, MD; Leonie Ruddick-Collins, PhD; Abhinav Vasudevan, MD; Jennifer Zhang, MD; Anthony Brownson, MD; Benjamin Ngoi, MD; Kate Lynch, MD; Craig Haifer, MD; Lucy Mary Lilian Bracken, MD; Ei Swe, MD; Emily Wright, MD; Nicholas Clark, MD; Tamar Schildkraut, MD; Gillian Mahy, MD; Gregory Moore, MD; Kathryn Gazelakis, MD; Mayur Garg, MD; Michael Schultz, MD
Asian Pacific Association of Gastroenterology (APAGE) Clinical Practice Guidelines on the Use of Small Molecules and IL-23 p19 Inhibitors in Ulcerative Colitis and Crohn's Disease

亚太胃肠病学协会(APAGE)关于小分子和IL-23 p19抑制剂在溃疡性结肠炎和克罗恩病中应用的临床实践指南

Journal of Gastroenterology and Hepatology
IF3.4
2026-05-120
OAAI
Choon Jin Ooi; Khoon Lin Ling; Julajak Limsrivilai; Shu-Chen Wei; Joyce Wing Yan Mak; Taku Kobayashi; Luan Minh Dang; Rupert W. Leong; Huiyu Lin; Meng-Tzu Weng; Wan Chee Ong; Vineet Ahuja; Satimai Aniwan; Ryota Hokari; Wei Jie Jonathan Lee; Alex Hwong-Ruey Leow; Wai-Keung Leung; Wee-Chian Lim; Govind Makharia; Katsuyoshi Matsuoka; Nazri Mustaffa; Siew-Chien Ng; Mathew Philip; Pises Pisespongsa; Raja Affendi Raja Ali; Zhi Hua Ran; Marcellus Simadibrata; Jose Sollano; Malcolm Tan; Hang Dao Viet; Nik Razima Wan Ibrahim; Kai Chun Wu; Byong Duk Ye; Ida Hilmi; Asian Pacific Association of Gastroenterology (APAGE) Inflammatory Bowel Disease Committee and Asian Education Network in IBD (AEN-IBD)
Time to rethink washout periods in inflammatory bowel disease clinical trials: an international Delphi consensus

是时候重新思考炎症性肠病临床试验中的清洗期：一项国际德尔菲共识

Journal of Crohn's and Colitis
IF8.7
2026-05-010
PRE
Pauline Wils; Vipul Jairath; Bruce E Sands; Axel Dignass; Fernando Magro; David T Rubin; Iris Dotan; Walter Reinisch; Parambir Dulai; Richard Gearry; Christopher Ma; Millie Long; Alessandro Armuzzi; Taku Kobayashi; Dan Turner; Sophie Vieujean; Bram Verstockt; Ailsa Hart; Silvio Danese; Laurent Peyrin-Biroulet
Mirikizumab four-year sustained and durable efficacy and safety in ulcerative colitis: Final findings from the LUCENT-3 open-label extension study

美瑞克zumab治疗溃疡性结肠炎四年的持续和持久疗效与安全性：来自LUCENT-3开放标签扩展研究的最终结果

Inflammatory Bowel Diseases
IF4.3
2026-03-020
OA
Bruce E Sands, MD; David B Clemow, PhD; Geert D’Haens, MD, PhD; Peter M Irving, MA, MD, FRCP; Taku Kobayashi, MD, PhD; Laurent Peyrin-Biroulet, MD, PhD; Karen Samaan, PharmD, BCCCP, BCNSP; Anil Gaur, PhD; Ravneet Arora, MD; Kris Todd, MSN; Richard Moses, DO, JD; Axel Dignass, MD, PhD
Personalized infliximab rescue therapy to maximize colectomy-free survival in patients with acute severe ulcerative colitis

针对急性重症溃疡性结肠炎患者的个性化英夫利昔单抗挽救治疗以最大化结肠切除术-free生存率

Journal of Crohns & Colitis
IF8.7
2026-03-010
PRE
Niyigena, Emmanuel; Hoffert, Yannick; Afif, Waqqas; Pedicelli, Alessandro; Roblin, Xavier; Hanzel, Jurij; Papamichael, Konstantinos; Kobayashi, Taku; Elens, Laure; Wang, Zhigang; Ferrante, Marc; Verstockt, Bram; Vermeire, Severine; Vande Casteele, Niels; Battat, Robert; Dreesen, Erwin
Safety and Efficacy of Ozanimod in Patients With Moderately to Severely Active Ulcerative Colitis Stratified by Age

奥扎尼妥（Ozanimod）在按年龄分层的中度至重度活动性溃疡性结肠炎患者中的安全性与有效性

INFLAMMATORY BOWEL DISEASES
IF4.3
2025-11-010
PRE
Faye, Adam S.; Rubin, David T.; Siegel, Corey A.; Long, Millie D.; Khan, Nabeel; Danese, Silvio; Irving, Peter M.; Cross, Raymond K.; Blumenstein, Irina; Armuzzi, Alessandro; Horst, Sara N.; Dignass, Axel; Kobayashi, Taku; Lawlor, Garrett; Krakovich, Anthony; Petersen, Annkatrin; Liu, Zhaohui; Wang, Dong; Jain, Anjali; Ananthakrishnan, Ashwin N.; Sabino, Joao
Mirikizumab Provides Sustained Long-Term Efficacy Up to 4 Years of Treatment for Ulcerative Colitis: Extended Induction Results From the LUCENT-3 Open-Label Study

Mirikizumab为溃疡性结肠炎患者提供长达4年的持续长期疗效：来自LUCENT-3开放标签研究的扩展诱导结果

AMERICAN JOURNAL OF GASTROENTEROLOGY
IF7.6
2025-10-010
PRE
Sands, Bruce E.; Clemow, David; D'Haens, Geert R.; Vermeire, Severine; Irving, Peter; Kobayashi, Taku; Peyrin-Biroulet, Laurent; Samaan, Karen; Gaur, Anil; Folian, Sarah; Arora, Ravneet; Paquette, Nicholas; Moses, Richard E.; Dignass, Axel
Optimising carotegrast methyl use in ulcerative colitis: patient profiling, predictive biomarkers, and timing of efficacy evaluation (ASPECT study)

优化卡托格斯特甲基在溃疡性结肠炎中的使用：患者特征分析、预测性生物标志物及疗效评估时机（ASPECT研究）

Journal of Gastroenterology
IF5.5
2025-09-220
OAAI
Katsuyoshi Matsuoka; Fumihito Hirai; Kenji Watanabe; Ryota Hokari; Taku Kobayashi; Masayuki Saruta; Hiroshi Nakase; Takahiro Suzuki; Gakuto Yamazaki; Toshifumi Hibi; Mamoru Watanabe; Tadakazu Hisamatsu
Mirikizumab impact on disease clearance in patients with moderately to severely active ulcerative colitis: analysis of a pre-specified LUCENT trial endpoint

Mirikizumab对中度至重度活动性溃疡性结肠炎患者疾病清除率的影响：对LUCENT试验预设终点的分析

JOURNAL OF CROHNS & COLITIS
IF8.7
2025-09-010
OAAI
Colombel, Jean-Frederic; Wu, Jianmin; Kobayashi, Taku; Zhu, Baojin; Paulissen, Jerome; Dhanabal, Agni; Jairath, Vipul; Siegel, Corey; Siegmund, Britta; Redondo, Isabel; Moses, Richard; Magro, Fernando
Asia Pacific association of gastroenterology consensus statements on histopathological evaluation of inflammatory bowel diseases

亚太胃肠病学协会关于炎症性肠病组织病理学评估的共识声明

Therapeutic Advances in Gastroenterology
IF3.4
2025-08-190
OA
Rupert W. Leong; Thanaboon Chaemsupaphan; Huiyu Lin; Wee Chian Lim; Choon Jin Ooi; John D. Chetwood; Ren Mao; Hsin Yun Wu; Shu Chen Wei; Govind Makharia; Vineet Ahuja; Rupa Banerjee; Raja Atreya; Julajak Limsrivilai; Satimai Aniwan; Pises Pisespongsa; Ida Hilmi; Raja Affendi Raja Ali; Wai Keung Leung; Siew C. Ng; Byong Duk Ye; Taku Kobayashi; Katsuyoshi Matsuoka; Cora Chau; Anapat Sanpavat; Chia-Tung Shun; Pavitratha Puspanathan; Richard B. Gearry; Silvio Danese; Christopher Ma; Aviv Pudipeddi; Sudarshan Paramsothy
Comparative effectiveness of tofacitinib versus upadacitinib for the treatment of acute severe ulcerative colitis

托法替布与乌帕替尼治疗急性重度溃疡性结肠炎的疗效比较

Clinical Gastroenterology and Hepatology
IF12
2025-07-260
OAAI
Sailish Honap; Joelle St-Pierre; Michael Colwill; Kamal Patel; Catherine Le Berre; Bénédicte Caron; Akira Nogami; Taku Kobayashi; Romain Altwegg; David Laharie; Xavier Hebuterne; Maria Nachury; Xavier Roblin; Mathieu Uzzan; Paulo Gustavo Kotze; Milan Lukáš; Sophie Vieujean; Ferdinando D’Amico; Ahmad Albshesh; Lucas Guillo; Mathurin Fumery; Stephane Nancey; Byong Duk Ye; Daniel Bergemalm; Jonas Halfvarson; Anthony Buisson; Konstantinos Karmiris; David Rubin; Eric Vicaut; Laurent Peyrin-Biroulet
Characteristic gene expression profile of intestinal mucosa early in life promotes bacterial colonization leading to healthy development of the intestinal environment

肠道黏膜早期生命中的特征性基因表达谱促进细菌定植，从而导致肠道环境的健康发育。

SCIENTIFIC REPORTS
IF3.9
2025-05-260
OA
Nishinarita, Yuu; Miyoshi, Jun; Kuronuma, Satoshi; Wada, Haruka; Oguri, Noriaki; Hibi, Noritaka; Takeuchi, Osamu; Akimoto, Yoshihiro; Lee, Sonny T. M.; Matsuura, Minoru; Kobayashi, Taku; Hibi, Toshifumi; Hisamatsu, Tadakazu
Real-World Effectiveness and Safety of Vedolizumab in Patients ≥ 70 Versus < 70 Years With Ulcerative Colitis: Multicenter Retrospective Study

溃疡性结肠炎患者中≥70岁与<70岁患者接受维多利珠单抗治疗的实际有效性与安全性：多中心回顾性研究

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
IF3.4
2025-05-150
OA
Hisamatsu, Tadakazu; Kobayashi, Taku; Motoya, Satoshi; Fujii, Toshimitsu; Kunisaki, Reiko; Shibuya, Tomoyoshi; Matsuura, Minoru; Hiraoka, Sakiko; Takeuchi, Ken; Yasuda, Hiroshi; Yokoyama, Kaoru; Takatsu, Noritaka; Maemoto, Atsuo; Tahara, Toshiyuki; Tominaga, Keiichi; Shimada, Masaaki; Kuno, Nobuaki; Fernandez, Jovelle L.; Hirose, Lisa; Ishiguro, Kaori; Cavaliere, Mary; Hibi, Toshifumi
Real-World Effectiveness and Safety of Mirikizumab Induction Therapy in Patients With Ulcerative Colitis: A Multicentre Retrospective Observational Study

真实世界中溃疡性结肠炎患者接受Mirikizumab诱导治疗的有效性与安全性：一项多中心回顾性观察性研究

ALIMENTARY PHARMACOLOGY & THERAPEUTICS
IF0
2025-04-092
OAAI
Takagi, Y; Sato, T; Nishiguchi, T; Nogami, A; Igeta, M; Yagi, S; Ikenouchi, M; Kawai, M; Kamikozuru, K; Yokoyama, Y; Tomita, T; Fukui, H; Fukata, M; Kobayashi, T; Shinzaki, S

研究方向

暂未获取到该数据
T
Toshifumi Hibi∥
H 指数:101论文数:1,436被引数:4.2万
K
Katsuyoshi Matsuoka
H 指数:52论文数:436被引数:1.0万
T
Tadakazu Hisamatsu
H 指数:60论文数:626被引数:1.4万
S
Shintaro Sagami
H 指数:14论文数:88被引数:613
S
Shinichiro Shinzaki
H 指数:35论文数:357被引数:4,813
M
Minoru Matsuura
H 指数:33论文数:278被引数:4,786
M
Mamoru Watanabe
H 指数:95论文数:1,448被引数:3.7万
M
Masayuki Saruta
H 指数:36论文数:302被引数:5,081
K
Kenji Watanabe
H 指数:50论文数:599被引数:1.0万
F
Fumihito Hirai
H 指数:40论文数:316被引数:6,215