未登录 Melanoma of unknown primary shows an oncogenic pattern and clinical course of sun-exposed melanoma 未知原发灶黑色素瘤表现出日晒暴露型黑色素瘤的致癌模式和临床病程 Lodde, Georg; Dollani, Jonida; Galetzka, Wolfgang; Mohr, Peter; Meier, Friedegund; Gutzmer, Ralf; Weichenthal, Michael; Utikal, Jochen; Herbst, Rudolf; Leiter, Ulrike; Pfoehler, Claudia; Schilling, Bastian; Terheyden, Patrick; Berking, Carola; Sucker, Antje; Stang, Andreas; Rambow, Florian; Tilkorn, Daniel; Roesch, Alexander; Zaremba, Anne; Zimmer, Lisa; Tasdogan, Alpaslan; Schadendorf, Dirk; Ugurel, Selma; Griewank, Klaus; Livingstone, Elisabeth 分享 收藏
Real-world data on anti-PD-1 plus lenvatinib as a treatment option in pretreated advanced melanoma patients-a retrospective DeCOG study PD-1抑制剂联合仑伐替尼作为经治晚期黑色素瘤患者治疗方案的现况数据——一项回顾性DeCOG研究 Albrecht, Lea Jessica; Garnier, Jana; Zaremba, Anne; Brauch, Lisa; Brunnert, Fiona; Rauschenberg, Ricarda; Forschner, Andrea; Vazquez, Xiomara Garza; Mangana, Joanna; Erdmann, Michael; Angela, Yenny; Franklin, Cindy; Tietze, Julia; Lodde, Georg; Tasdogan, Alpaslan; Seier, Johanna A.; Roesch, Alexander; Ugurel, Selma; Berking, Carola; Gutzmer, Ralf; Heinzerling, Lucie; Meier, Friedegund; Mohr, Peter; Hassel, Jessica C.; Schadendorf, Dirk; Livingstone, Elisabeth; Zimmer, Lisa 分享 收藏
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Presence of brain metastasis differentially impacts long-term survival after first-line therapy in melanoma depending on BRAF mutation status 根据BRAF突变状态，脑转移的存在会对黑色素瘤一线治疗后的长期生存产生不同的影响 Placke, Jan-Malte; Rajcsanyi, Luisa Sophie; Herbst, Rudolf; Terheyden, Patrick; Utikal, Jochen; Pfoehler, Claudia; Kreuter, Alexander; Mohr, Peter; Gutzmer, Ralf; Weichenthal, Michael; Meier, Friedegund; Berking, Carola; Leiter, Ulrike; Seier, Johanna; Krefting, Frederik; Tasdogan, Alpaslan; Lodde, Georg C.; Livingstone, Elisabeth; Zimmer, Lisa; Roesch, Alexander; Griewank, Klaus; Schadendorf, Dirk; Ugurel, Selma 分享 收藏
Early versus late response to PD-1-based immunotherapy in metastatic melanoma 转移性黑色素瘤对PD-1-based免疫治疗的早期与晚期反应 Lodde, Georg C.; Zhao, Fang; Herbst, Rudolf; Terheyden, Patrick; Utikal, Jochen; Pfoehler, Claudia; Ulrich, Jens; Kreuter, Alexander; Mohr, Peter; Gutzmer, Ralf; Meier, Friedegund; Dippel, Edgar; Weichenthal, Michael; Jansen, Philipp; Kowall, Bernd; Galetzka, Wolfgang; Hoerst, Fabian; Kleesiek, Jens; Hellwig, Birte; Rahnenfuehrer, Jorg; Rajcsanyi, Luisa; Peters, Triinu; Hinney, Anke; Placke, Jan-Malte; Sucker, Antje; Paschen, Annette; Becker, Juergen C.; Livingstone, Elisabeth; Zimmer, Lisa; Tasdogan, Alpaslan; Roesch, Alexander; Hadaschik, Eva; Schadendorf, Dirk; Griewank, Klaus; Ugurel, Selma 分享 收藏
Early switch from targeted to immunotherapy in advanced BRAFV600-positive melanoma: Long-term OS and final PFS results of the randomized phase II ImmunoCobiVem trial 在BRAFV600阳性晚期黑色素瘤中早期从靶向治疗转为免疫治疗：随机II期ImmunoCobiVem试验的长期OS和最终PFS结果 Schadendorf, D.; Gogas, H.; Sekulovic, L. Kandolf; Meier, F.; Eigentler, T. K.; Ziemer, M.; Terheyden, P.; Gesierich, A.; Herbst, R.; Kaeler, K. C.; Ziogas, D. C.; Mijuskovic, Z.; Garzarolli, M.; Garbe, C.; Roesch, A.; Ugurel-Becker, S.; Gutzmer, R.; Grob, J. J.; Zimmer, L.; Livingstone, E. 分享 收藏
Anti-PD-(L)1 plus BRAF/MEK inhibitors (triplet therapy) after failure of immune checkpoint inhibition and targeted therapy in patients with advanced melanoma 晚期黑色素瘤患者免疫检查点抑制和靶向治疗失败后，抗PD-(L)1联合BRAF/MEK抑制剂 (三联疗法) Albrecht, Lea Jessica; Dimitriou, Florentia; Grover, Piyush; Hassel, Jessica C.; Erdmann, Michael; Forschner, Andrea; Johnson, Douglas B.; Varaljai, Renata; Lodde, Georg; Placke, Jan Malte; Krefting, Frederik; Zaremba, Anne; Ugurel, Selma; Roesch, Alexander; Schulz, Carsten; Berking, Carola; Poettgen, Christoph; Menzies, Alexander M.; Long, Georgina V.; Dummer, Reinhard; Livingstone, Elisabeth; Schadendorf, Dirk; Zimmer, Lisa 分享 收藏
Comprehensive pan-cancer analysis of cfDNA methylation marks in tumors reveals complex epigenetic regulatory circuits and diagnostic biomarkers Lueong, Smiths Sengkwawoh; Metzenmacher, Martin; Zaun, Gregor; Mayer, Gina Lauren; Hemmer, Erik Jan; Luckerath, Katharina; Pomykala, Kelsey; Hegedus, Balazs; Horn, Peter A.; Trajkovic-Arsic, Marija; Szarvas, Tibor; Varaljai, Renata; Keup, Corinna; Tinhofer, Ingeborg; George, Stephen; Kasimir-Bauer, Sabine; Pena-Llopis, Samuel; Roesch, Alexander; Kurten, Cornelius; Boosfeld, Lukas; Bruderek, Kirsten; Darr, Christopher; Hilser, Thomas; Grunwald, Viktor; Brandau, Sven; Hadaschik, Boris; Neubauer, Hans; Esposito, Irene Irene Irene Esposito; Fehm, Tanja; Olah, Csilla; Csizmarik, Anita; Thangarajah, Fabinshy; Reetz, Laura; Jamal, Ghanam; Thakur, Basant Kumar; Kalkavan, Halime; Schramm, Alexander; Schuler, Martin; Siveke, Jens T. 分享 收藏
Association of antibiotic treatment with survival outcomes in treatment-naïve melanoma patients receiving immune checkpoint blockade 抗生素治疗与接受免疫检查点阻断的治疗初治黑色素瘤患者的生存结果的关联 Chorti, Eleftheria; Kowall, Bernd; Hassel, Jessica C.; Schilling, Bastian; Sachse, Michael; Gutzmer, Ralf; Loquai, Carmen; Kaehler, Katharina C.; Huesing, Anika; Gilde, Catharina; Thielmann, Carl M.; Zaremba-Montenari, Anne; Placke, Jan-Malte; Gratsias, Emmanouil; Martaki, Anna; Roesch, Alexander; Ugurel, Selma; Schadendorf, Dirk; Livingstone, Elisabeth; Stang, Andreas; Zimmer, Lisa 分享 收藏
Correlation of tumor PD-L1 expression in different tissue types and outcome of PD-1-based immunotherapy in metastatic melanoma - analysis of the DeCOG prospective multicenter cohort study ADOREG/TRIM 不同组织类型中肿瘤PD-L1表达与转移性黑色素瘤PD-1-based免疫治疗结果的相关性-DeCOG前瞻性多中心队列研究adorig/TRIM的分析 Placke, Jan-Malte; Kimmig, Mona; Griewank, Klaus; Herbst, Rudolf; Terheyden, Patrick; Utikal, Jochen; Pfoehler, Claudia; Ulrich, Jens; Kreuter, Alexander; Mohr, Peter; Gutzmer, Ralf; Meier, Friedegund; Dippel, Edgar; Welzel, Julia; Engel, Daniel Robert; Kreft, Sophia; Sucker, Antje; Lodde, Georg; Krefting, Frederik; Stoffels, Ingo; Klode, Joachim; Roesch, Alexander; Zimmer, Lisa; Livingstone, Elisabeth; Hadaschik, Eva; Becker, Juergen C.; Weichenthal, Michael; Tasdogan, Alpaslan; Schadendorf, Dirk; Ugurel, Selma 分享 收藏
Adjuvant treatment and outcome of stage III melanoma patients: Results of a multicenter real-world German Dermatologic Cooperative Oncology Group (DeCOG) study III期黑色素瘤患者的辅助治疗和结果: 多中心真实世界德国皮肤肿瘤协作组 (DeCOG) 研究的结果 Lodde, Georg C.; Hassel, Jessica; Wulfken, Lena M.; Meier, Friedegund; Mohr, Peter; Kaehler, Katharina; Hauschild, Axel; Schilling, Bastian; Loquai, Carmen; Berking, Carola; Huening, Svea; Eckardt, Julia; Gutzmer, Ralf; Reinhardt, Lydia; Glutsch, Valerie; Nikfarjam, Ulrike; Erdmann, Michael; Beckmann, Catharina L.; Stang, Andreas; Kowall, Bernd; Galetzka, Wolfgang; Roesch, Alexander; Ugurel, Selma; Zimmer, Lisa; Schadendorf, Dirk; Forschner, Andrea; Livingstone, Elisabeth 分享 收藏
Early switch from run-in treatment with vemurafenib plus cobimetinib to atezolizumab after 3 months leads to rapid loss of tumour control in patients with advanced BRAFV600-positive melanoma: The ImmunoCobiVem phase 2 randomised trial Livingstone, E.; Gogas, H.; Kandolf-Sekulovic, L.; Meier, F.; Eigentler, T. K.; Ziemer, M.; Terheyden, P. A. M.; Gesierich, A. H.; Herbst, R. A.; Kaehler, K. C.; Ziogas, D. C.; Mijuskovic, Z.; Garzarolli, M.; Garbe, C.; Roesch, A.; Ugurel, S.; Gutzmer, R.; Grob, J. J.; Kiecker, F.; Utikal, J.; Windemuth-Kieselbach, C.; Eckhardt, S.; Zimmer, L.; Schadendorf, D. 分享 收藏
Integrative multi-omics reveals two biologically distinct groups of pilocytic astrocytoma 整合多组学揭示了两个生物学上不同的毛细胞星形细胞瘤组 Picard, Daniel; Felsberg, Joerg; Langini, Maike; Stachura, Pawel; Qin, Nan; Macas, Jadranka; Reiss, Yvonne; Bartl, Jasmin; Selt, Florian; Sigaud, Romain; Meyer, Frauke-D.; Stefanski, Anja; Stuehler, Kai; Roque, Lucia; Roque, Rafael; Pandyra, Aleksandra A.; Brozou, Triantafyllia; Knobbe-Thomsen, Christiane; Plate, Karl H.; Roesch, Alexander; Milde, Till; Reifenberger, Guido; Leprivier, Gabriel; Faria, Claudia C.; Remke, Marc 分享 收藏
Interleukin 17 signaling supports clinical benefit of dual CTLA-4 and PD-1 checkpoint inhibition in melanoma (Jul, 10.1038/s43018-023-00610-2, 2023) 白细胞介素17信号支持双重CTLA-4和PD-1检查点抑制在黑色素瘤中的临床益处 (7月，10.1038/s43018-023-00610-2，2023) Varaljai, Renata; Zimmer, Lisa; Al-Matary, Yahya; Kaptein, Paulien; Albrecht, Lea J.; Shannan, Batool; Brase, Jan C.; Gusenleitner, Daniel; Amaral, Teresa; Wyss, Nina; Utikal, Jochen; Flatz, Lukas; Rambow, Florian; Reinhardt, Hans Christian; Dick, Jenny; Engel, Daniel R.; Horn, Susanne; Ugurel, Selma; Sondermann, Wiebke; Livingstone, Elisabeth; Sucker, Antje; Paschen, Annette; Zhao, Fang; Placke, Jan M.; Klose, Jasmin M.; Fendler, Wolfgang P.; Thommen, Daniela S.; Helfrich, Iris; Schadendorf, Dirk; Roesch, Alexander 分享 收藏
Interleukin 17 signaling supports clinical benefit of dual CTLA-4 and PD-1 checkpoint inhibition in melanoma 白细胞介素17信号支持黑色素瘤双重CTLA-4和PD-1检查点抑制的临床益处 Varaljai, Renata; Zimmer, Lisa; Al-Matary, Yahya; Kaptein, Paulien; Albrecht, Lea J.; Shannan, Batool; Brase, Jan C.; Gusenleitner, Daniel; Amaral, Teresa; Wyss, Nina; Utikal, Jochen; Flatz, Lukas; Rambow, Florian; Reinhardt, Hans Christian; Dick, Jenny; Engel, Daniel R.; Horn, Susanne; Ugurel, Selma; Sondermann, Wiebke; Livingstone, Elisabeth; Sucker, Antje; Paschen, Annette; Zhao, Fang; Placke, Jan M.; Klose, Jasmin M.; Fendler, Wolfgang P.; Thommen, Daniela S.; Helfrich, Iris; Schadendorf, Dirk; Roesch, Alexander 分享 收藏
Reduced Staphylococcus Abundance Characterizes the Lesional Microbiome of Actinic Keratosis Patients after Field-Directed Therapies Kehrmann, Jan; Koch, Fiona; Zumdick, Skrollan; Hoewner, Anna; Best, Lara; Masshoefer, Lars; Scharfenberg, Sarah; Zeschnigk, Michael; Becker, Juergen C.; Schadendorf, Dirk; Buer, Jan; Roesch, Alexander 分享 收藏
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Circulating cell-free messenger RNA enables non-invasive pan-tumour monitoring of melanoma therapy independent of the mutational genotype Albrecht, Lea Jessica; Hoewner, Anna; Griewank, Klaus; Lueong, Smiths S.; von Neuhoff, Nils; Horn, Peter A.; Sucker, Antje; Paschen, Annette; Livingstone, Elisabeth; Ugurel, Selma; Zimmer, Lisa; Horn, Susanne; Siveke, Jens T.; Schadendorf, Dirk; Varaljai, Renata; Roesch, Alexander 分享 收藏
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