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Evolutionary and immune microenvironment dynamics during neoadjuvant treatment of esophageal adenocarcinoma 食管腺癌新辅助治疗期间的肿瘤进化与免疫微环境动力学 Barroux, Melissa; Househam, Jacob; Lakatos, Eszter; Ronel, Tahel; Baker, Ann-Marie; Salie, Henrike; Mossner, Maximilian; Smith, Kane; Kimberley, Chris; Nowinski, Salpie; Berner, Alison; Gunasri, Vinaya; Borgmann, Martin; Liffers, Sven; Jansen, Marnix; Caravagna, Giulio; Steiger, Katja; Slotta-Huspenina, Julia; Weichert, Wilko; Zapata, Luis; Giota, Eleftheria; Lorenzen, Sylvie; Alberstmeier, Markus; Chain, Benny; Friess, Helmut; Bengsch, Bertram; Schmid, Roland M.; Siveke, Jens T.; Quante, Michael; Graham, Trevor A. 分享 收藏
Low-coverage whole genome sequencing of low-grade dysplasia strongly predicts advanced neoplasia risk in ulcerative colitis 低覆盖度全基因组测序对溃疡性结肠炎中低级别异型增生的癌前病变进展风险具有强预测作用 Al Bakir, Ibrahim; Curtius, Kit; Cresswell, George D.; Grant, Heather E.; Nasreddin, Nadia; Smith, Kane; Nowinski, Salpie; Guo, Qingli; Belnoue-Davis, Hayley L.; Fisher, Jennifer; Clarke, Theo; Kimberley, Christopher; Mossner, Maximilian; Dunne, Philip D.; Loughrey, Maurice B.; Speight, Ally; East, James E.; Wright, Nicholas A.; Rodriguez-Justo, Manuel; Jansen, Marnix; Moorghen, Morgan; Baker, Ann-Marie; Leedham, Simon J.; Hart, Ailsa L.; Graham, Trevor A. 分享 收藏
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The Stratified Medicine Paediatrics programme for cancers of childhood: Cell free DNA and serial tumour sequencing identifies subtype specific evolution and epigenetic states 儿童癌症分层医学儿科计划: 无细胞DNA和连续肿瘤测序确定亚型特异性进化和表观遗传状态 George, Sally L.; Lynn, Claire; Stankunaite, Reda; Hughes, Debbie; Chalker, Jane; Ahmed, Saira Waqar; Oostveen, Minou; Proszek, Paula; Yuan, Lina; Shaikh, Ridwan; Jamal, Sabri; Tall, Jennifer; Shipley, Janet; Tweddle, Deborah; Marshall, Lynley; Jones, Chris; Gatz, Susanne; Vedi, Aditi; Angelini, Paola; Anderson, John; Cresswell, George; Graham, Trevor A.; Al-Lazikani, Bissan; Kearns, Pamela; Hutchinson, J. Ciaran; Hargrave, Darren; Jacques, Thomas; Hubank, Michael; Sottoriva, Andrea; Chesler, Louis 分享 收藏
Dynamic Prediction of Advanced Colorectal Neoplasia in Inflammatory Bowel Disease Wijnands, Anouk M.; de Vries, Bas B. L. Penning; Lutgens, Maurice W. M. D.; Bakhshi, Zeinab; Al Bakir, Ibrahim; Beaugerie, Laurent; Bernstein, Charles N.; Choi, Ryan Chang-ho; Coelho-Prabhu, Nayantara; Graham, Trevor A.; Hart, Ailsa L.; ten Hove, Joren R.; Itzkowitz, Steven H.; Kirchgesner, Julien; Mooiweer, Erik; Shaffer, Seth R.; Shah, Shailja C.; Elias, Sjoerd G.; Oldenburg, Bas 分享 收藏
Homopolymer switches mediate adaptive mutability in mismatch repair-deficient colorectal cancer 均聚物开关介导错配修复缺陷型结直肠癌的适应性可变性 Kayhanian, Hamzeh; Cross, William; van der Horst, Suzanne E. M.; Barmpoutis, Panagiotis; Lakatos, Eszter; Caravagna, Giulio; Zapata, Luis; Van Hoeck, Arne; Middelkamp, Sjors; Litchfield, Kevin; Steele, Christopher; Waddingham, William; Patel, Dominic; Milite, Salvatore; Jin, Chen; Baker, Ann-Marie; Alexander, Daniel C.; Khan, Khurum; Hochhauser, Daniel; Novelli, Marco; Werner, Benjamin; van Boxtel, Ruben; Hageman, Joris H.; Buissant des Amorie, Julian R.; Linares, Josep; Ligtenberg, Marjolijn J. L.; Nagtegaal, Iris D.; Lacle, Miangela M.; Moons, Leon M. G.; Brosens, Lodewijk A. A.; Pillay, Nischalan; Sottoriva, Andrea; Graham, Trevor A.; Rodriguez-Justo, Manuel; Shiu, Kai-Keen; Snippert, Hugo J. G.; Jansen, Marnix 分享 收藏
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Evolutionary and immune microenvironment dynamics determine response to neoadjuvant treatment of oesophageal adenocarcinoma Barroux, M.; Househam, J.; Lakatos, E.; Ronel, T.; Baker, A-M.; Salie, H.; Mossner, M.; Jansen, M.; Caravagna, G.; Steiger, K.; Slotta-Huspenina, J.; Weichert, W.; Alberstmeier, M.; Chain, B.; Friess, H.; Bengsch, B.; Schmid, R.; Siveke, J. T.; Quante, M.; Graham, T. 分享 收藏
Profiling of Copy Number Alterations Using Low-Coverage Whole-Genome Sequencing Informs Differential Diagnosis and Prognosis in Primary Cutaneous Follicle Center Lymphoma Batai, Bence; Kiss, Laura; Varga, Luca; Nagy, Akos; Househam, Jacob; Baker, Ann-Marie; Laszlo, Tamas; Udvari, Anna; Horvath, Robert; Nagy, Tibor; Csomor, Judit; Szakonyi, Jozsef; Schneider, Tamas; Graham, Trevor A.; Alpar, Donat; Fitzgibbon, Jude; Szepesi, Agota; Bodor, Csaba 分享 收藏
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Large-scale, low-cost, and accurate measurement of cancer evolutionary dynamics from clinical patient samples Gabbutt, Calum; Duran-Ferrer, Marti; Grant, Heather; Mallo, Diego; Nadeu, Ferran; Househam, Jacob; Villamor, Neus; Krali, Olga; Nordlund, Jessica; Zenz, Thorsten; Campo, Elias; Lopez-Guillermo, Armando; Fitzgibbon, Jude; Barnes, Chris P.; Shibata, Darryl; Martin-Subero, Jose I.; Graham, Trevor A. 分享 收藏
FUME-TCRseq Enables Sensitive and Accurate Sequencing of the T-cell Receptor from Limited Input of Degraded RNA Baker, Ann-Marie; Nageswaran, Gayathri; Nenclares, Pablo; Ronel, Tahel; Smith, Kane; Kimberley, Christopher; Lacle, Miangela M.; Bhide, Shreerang; Harrington, Kevin J.; Melcher, Alan; Rodriguez-Justo, Manuel; Chain, Benny; Graham, Trevor A. 分享 收藏
Poor Diagnostic Reproducibility in the Identification of Nonconventional Dysplasia in Colitis Impacts the Application of Histologic Stratification Tools Nasreddin, Nadia; Jansen, Marnix; Loughrey, Maurice B.; Wang, Lai Mun; Koelzer, Viktor H.; Rodriguez-Justo, Manuel; Novelli, Marco; Fisher, Jennifer; Brown, Matthew W.; Al Bakir, Ibrahim; Hart, Ailsa L.; Dunne, Philip; Graham, Trevor A.; Leedham, Simon J. 分享 收藏
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