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王

王兰 (Lan Wang)

shanghai institute of nutrition and health university of chinese academy of sciences chinese academy of sciences
H指数:31
被引数:4,411

个人简介

"2017－至 今 中国科学院上海营养与健康研究院，研究员 2015－2016 中国科学院上海生命科学研究院/上海交通大学医学院 健康科学研究所，研究员 2013－2015 美国迈阿密大学，生物化学与分子生物学系，助理教授（tenure track） 2007－2013 美国纪念斯隆凯特琳癌症中心博士后 2002－2007 中科院上海生命科学院健康科学研究所，生物化学与分子生物学博士 1998－2002 复旦大学生命科学院，生物学士"

教育背景

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工作经历

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荣誉奖项

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Tumor metastasis co-opts liver hematopoiesis to promote immunosuppression

肿瘤转移劫持肝脏造血以促进免疫抑制

Science
IF45.8
2026-11-050
PRE
Qiang Pan; Xuege Wang; Yaqi Li; Ni Li; Ying Han; Guoying Zhang; Jiacheng Guo; Le Zhang; Aoyuan Cui; Yongqiang Gu; Yannan Lian; Wei Zhang; Naiheng Lin; Beitao Xu; Zige Jin; Xin Zeng; Lan Wang; Yu Li; Junjie Peng; Xiaoming Wang; Zhengquan Yu; Gui-Hua Wang; Wei Lu; Jun Qin
Targeting RBPMS selectively eliminates FOXO1-mediated stem cell signatures in mouse models of acute myeloid leukemia

靶向RBPMS选择性消除小鼠急性髓系白血病模型中FOXO1介导的干细胞特征

Science Translational Medicine
IF14.6
2026-05-060
PRE
Ping Liu; Sulin Zhang; Bing-Yi Chen; Binhe Chang; Yilun Jiang; Xiya Li; Xinchi Chen; Zi-juan Li; Ruirui Yang; Xiaoning Wang; Chun-Hui Xu; Xiaomeng Liu; Na Liu; Yuanyuan Jia; Peng-Cheng Yu; Yong Wang; Li-juan Zong; Cheng-Long Hu; Hui Hou; Duanhua Cao; Xutong Li; Chu-Han Deng; Yi-Yi Ren; Mu-ying Zhao; Xinyi Ma; Rongrong Cui; Dan Teng; Miao Chen; Roujia Wang; Jiacheng Jin; Shi-yu Jiang; Xiaojing Yan; Kai Xue; Qunling Zhang; Jianfeng Li; Enyong Dai; Shuhong Shen; Zhikai Wang; Xueshi Ye; Jin Zhang; Yu Liu; Wenguo Cui; Min Lu; Wei-Li Zhao; Chun-Kang Chang; Peng-Cheng He; Zhu Chen; Sai-Juan Chen; Mingyue Zheng; Xiao-Jian Sun; Lan Wang
Site-specific methylation of SRSF2P95H by SETD2 inhibits MDSC-mediated proinflammatory niche formation in mouse models of myelodysplastic syndrome

SETD2介导的SRSF2P95H位点特异性甲基化抑制了小鼠骨髓增生异常综合征模型中MDSC介导的促炎微环境形成。

Science Translational Medicine
IF14.6
2026-04-010
PRE
Zi-Juan Li; Mu-Ying Zhao; Roujia Wang; Na Liu; Cheng-Long Hu; Binhe Chang; Fang Hu; Xi-Ya Li; Chun-Hui Xu; Ping Liu; Bing-Yi Chen; Shu-Bei Chen; Yong Wang; Qi-Jing Li; Bu-Sheng Xue; Chuhan Deng; Xinchi Chen; Yiyi Ren; Jia-Cheng Jin; Xiao Yan; Yuanliang Zhang; Robert Peter Gale; Jianfei Fu; Qun-ling Zhang; Xiaoning Wang; Qiuhua Huang; Yan Liu; Ju Qiu; Jun Qin; Xueshi Ye; Jin Zhang; Yang Liang; Zhu Chen; Sai-Juan Chen; Peng-Cheng He; Chun-Kang Chang; Xiao-Jian Sun; Lan Wang
Author Correction: setd2 knockout zebrafish is viable and fertile: differential and developmental stress-related requirements for Setd2 and histone H3K36 trimethylation in different vertebrate animals

作者更正：Setd2基因敲除斑马鱼具有存活能力和生育能力：不同脊椎动物中Setd2和组蛋白H3K36三甲基化在差异性和发育性应激相关需求上的差异

Cell Discovery
IF12.5
2025-11-170
OAAI
Dian-Jia Liu; Fan Zhang; Yi Chen; Yi Jin; Yuan-Liang Zhang; Shu-Bei Chen; Yin-Yin Xie; Qiu-Hua Huang; Wei-Li Zhao; Lan Wang; Peng-Fei Xu; Zhu Chen; Sai-Juan Chen; Bing Li; Aijun Zhang; Xiao-Jian Sun
Clinically associated genomic landscape of pediatric non-Down Syndrome acute megakaryoblastic leukemia in Chinese patients

中国患者中与临床相关的儿科非唐氏综合征急性巨核细胞白血病的基因组景观

Leukemia
IF13.4
2025-08-110
PRE
Kefei Wu; Hui Liu; Wenting Hu; Yuhan Liu; Wenyan Wu; Bowen Cui; Han Wang; Shuang Zhao; Yanjing Tang; Jiaoyang Cai; Yong Wang; Xiang Wang; Xiaoxiao Chen; Yixiao Mo; Ting Liu; Yangyang Xie; Huiying Sun; Ying Zhong; Jianan Rao; Rongrong Fan; Ying Wang; Changcheng Chen; Zhuo Wang; Ronghua Wang; Yuanlu Huang; Qiaoqiao Shi; Lan Wang; Jing Chen; Jing Chen; Benshang Li; Xiaolong Chen; Yu Liu; Shuhong Shen
ROBO1 deficiency impairs HSPC homeostasis and erythropoiesis via CDC42 and predicts poor prognosis in MDS
SCIENCE ADVANCES
IF12.5
2023-12-010
OAAI
Jin, Jia-Cheng; Chen, Bing-Yi; Chen, Jia-Nan; Deng, Chu-Han; Xu, Feng; Tao, Ying; Hu, Cheng-Long; Xu, Chun-Hui; Chang, Bin-He; Wang, Yong; Fei, Ming-Yue; Liu, Ping; Yu, Peng-Cheng; Li, Zi-Juan; Li, Xi-Ya; Chen, Shu-Bei; Jiang, Yi-Lun; Chen, Xin-Chi; Zong, Li-Juan; Zhang, Jia-Ying; Ren, Yi-Yi; Xu, Fan-Huan; Liu, Qi; Huang, Xin-Hui; Guo, Juan; He, Qi; Song, Lu-Xi; Zhou, Li-Yu; Su, Ji-Ying; Xiao, Chao; Zhang, Yu-Mei; Yan, Meng; Zhang, Zheng; Wu, Dong; Chang, Chun-Kang; Li, Xiao; Wang, Lan; Wu, Ling-Yun
STING activation in TET2-mutated hematopoietic stem/progenitor cells contributes to the increased self-renewal and neoplastic transformation

TET2-mutated造血干/祖细胞的STING激活有助于增加自我更新和肿瘤转化

LEUKEMIA
IF13.4
2023-10-1011
OAAI
Xie, Jiaying; Sheng, Mengyao; Rong, Shaoqin; Zhou, Dan; Wang, Chao; Wu, Wanling; Huang, Jingru; Sun, Yue; Wang, Yin; Chen, Pingyue; Wu, Yushuang; Wang, Yuanxian; Wang, Lan; Zhou, Bo O.; Huang, Xinxin; Walsh, Colum P.; Bohlander, Stefan K.; Huang, Jian; Wang, Xiaoqin; Xu, Guo-Liang; Gao, Hai; Shi, Yuheng
Inhibition of USP1 reverses the chemotherapy resistance through destabilization of MAX in the relapsed/refractory B-cell lymphoma
LEUKEMIA
IF13.4
2022-11-0916
OAAI
Li, Xi-Ya; Wu, Ji-Chuan; Liu, Ping; Li, Zi-Juan; Wang, Yong; Chen, Bing-Yi; Hu, Cheng-Long; Fei, Ming-Yue; Yu, Peng-Cheng; Jiang, Yi-Lun; Xu, Chun-Hui; Chang, Bin-He; Chen, Xin-Chi; Zong, Li-Juan; Zhang, Jia-Ying; Fang, Ying; Sun, Xiao-Jian; Xue, Kai; Wang, Li; Chen, Shu-Bei; Jiang, Shi-Yu; Gui, Ai-ling; Yang, Ling; Gu, Juan J.; Yu, Bao-Hua; Zhang, Qun-ling; Wang, Lan
Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia

靶向UHRF1-SAP30-MXD4轴在髓系白血病起始细胞根除中的应用

CELL RESEARCH
IF25.9
2022-10-2713
OA
Hu, Cheng-Long; Chen, Bing-Yi; Li, Zijuan; Yang, Tianbiao; Xu, Chun-Hui; Yang, Ruirui; Yu, Peng-Cheng; Zhao, Jingyao; Liu, Ting; Liu, Na; Shan, Bin; Zhang, Qunling; Song, Junhong; Fei, Ming-Yue; Zong, Li-Juan; Zhang, Jia-Ying; Wu, Ji-Chuan; Chen, Shu-Bei; Wang, Yong; Chang, Binhe; Hou, Dan; Liu, Ping; Jiang, Yilun; Li, Xiya; Chen, Xinchi; Deng, Chu-Han; Ren, Yi-Yi; Wang, Roujia; Jin, Jiacheng; Xue, Kai; Zhang, Ying; Du, Meirong; Shi, Jun; Wu, Ling-Yun; Chang, Chun-Kang; Shen, Shuhong; Chen, Zhu; Chen, Sai-Juan; Liu, Xiaolong; Sun, Xiao-Jian; Zheng, Mingyue; Wang, Lan

研究方向

造血干细胞恶性转化血液肿瘤研究造血干细胞/白血病干细胞自我更新调控白血病致病癌蛋白的翻译后修饰造血干细胞恶性转化的分子机制癌症诊疗应用表观遗传学及转录调控在血液肿瘤和造血干细胞中的作用血液肿瘤和造血干细胞的代谢机制RNA剪切在血液肿瘤和造血干细胞中的作用
SUN XiaoJian 封面图
SUN XiaoJian
H 指数:57论文数:197被引数:1.4万
C
Chunhui Xu
H 指数:38论文数:164被引数:1.0万
黄
黄秋花
H 指数:24论文数:136被引数:4,051
B
Bingyi Chen
H 指数:19论文数:81被引数:784
S
Stephen D. Nimer
H 指数:80论文数:524被引数:2.4万
陈
陈赛娟
H 指数:73论文数:458被引数:2.4万
S
Shu-Bei Chen
H 指数:7论文数:9被引数:193
Y
Yinyin Xie
H 指数:15论文数:57被引数:1,246
C
Cheng-Long Hu
H 指数:9论文数:19被引数:250
张
张元良
H 指数:16论文数:111被引数:1,046