未登录 Heterogeneity of IKZF1 genomic alterations and risk of relapse in childhood B-cell precursor acute lymphoblastic leukemia IKZF1基因组变异的异质性与儿童前体B细胞急性淋巴细胞白血病的复发风险 Wang'ondu, Ruth W.; Ashcraft, Emily; Chang, Ti-Cheng; Roberts, Kathryn G.; Brady, Samuel W.; Fan, Yiping; Evans, William; Relling, Mary V.; Crews, Kristine R.; Yang, Jun; Yang, Wenjian; Pounds, Stanley; Wu, Gang; Devidas, Meenakshi; Maloney, Kelly; Mattano, Leonard; Schore, Reuven J.; Angiolillo, Anne; Larsen, Eric; Salzer, Wanda; Burke, Michael J.; Loh, Mignon L.; Jeha, Sima; Pui, Ching-Hon; Inaba, Hiroto; Cheng, Cheng; Mullighan, Charles G. 分享 收藏
Outcomes in patients with ETV6::RUNX1 or high-hyperdiploid B-ALL treated in the St. Jude Total Therapy XV/XVI studies ETV6::RUNX1或高超二倍体B-ALL患者在接受St. Jude Total Therapy XV/XVI研究治疗后结果 Purvis, Katelyn; Zhou, Yinmei; Karol, Seth E.; Rubnitz, Jeffrey E.; Ribeiro, Raul C.; Lee, Shawn; Yang, Jun J.; Bowman, W. Paul; Wang, Lu; Dixon, Stephanie B.; Roberts, Kathryn G.; Gao, Qingsong; Cheng, Cheng; Mullighan, Charles G.; Jeha, Sima; Pui, Ching-Hon; Inaba, Hiroto 分享 收藏
Revolutionizing B-ALL Cell Line Development: Novel Generation to Uncover Therapeutic Vulnerabilities 革新B-ALL细胞系开发：新型构建以揭示治疗易感性 Wu, Yiming; Szoltysek, Katarzyna; Brown, Tony; Backhaus, Emily; Khan, Tanya; Gao, Qingsong; Brewer, Amanda; Chang, Yunchao; Roberts, Kathryn G.; Crews, Kristine R.; Iacobucci, Ilaria; Wang'ondu, Ruth; Mullighan, Charles G. 分享 收藏
Blinatumomab for MRD-Negative Acute Lymphoblastic Leukemia in Adults Blinatumomab治疗成人MRD阴性急性淋巴细胞白血病 Litzow, M. R.; Sun, Z.; Mattison, R. J.; Paietta, E. M.; Roberts, K. G.; Zhang, Y.; Racevskis, J.; Lazarus, H. M.; Rowe, J. M.; Arber, D. A.; Wieduwilt, M. J.; Liedtke, M.; Bergeron, J.; Wood, B. L.; Zhao, Y.; Wu, G.; Chang, T-C; Zhang, W.; Pratz, K. W.; Dinner, S. N.; Frey, N.; Gore, S. D.; Bhatnagar, B.; Atallah, E. L.; Uy, G. L.; Jeyakumar, D.; Lin, T. L.; Willman, C. L.; DeAngelo, D. J.; Patel, S. B.; Elliott, M. A.; Advani, A. S.; Tzachanis, D.; Vachhani, P.; Bhave, R. R.; Sharon, E.; Little, R. F.; Erba, H. P.; Stone, R. M.; Luger, S. M.; Mullighan, C. G.; Tallman, M. S. 分享 收藏
Biologic and Clinical Analysis of Childhood Gamma Delta T-ALL Identifies LMO2/STAG2 Rearrangements as Extremely High Risk 儿童 γ δ t-all的生物学和临床分析将LMO2/STAG2重排确定为极高风险 Kimura, Shunsuke; Park, Chun Shik; Montefiori, Lindsey E.; Iacobucci, Ilaria; Poeloenen, Petri; Gao, Qingsong; Arnold, Elizabeth D.; Attarbaschi, Andishe; Brown, Anthony; Buldini, Barbara; Caldwell, Kenneth J.; Chang, Yunchao; Chen, Chelsey; Cheng, Cheng; Cheng, Zhongshan; Choi, John; Conter, Valentino; Crews, Kristine R.; de Groot-Kruseman, Hester A.; Deguchi, Takao; Eguchi, Mariko; Muhle, Hannah E.; Elitzur, Sarah; Escherich, Gabriele; Freeman, Burgess B.; Gu, Zhaohui; Han, Katie; Horibe, Keizo; Imamura, Toshihiko; Jeha, Sima; Kato, Motohiro; Chiew, Kean H.; Khan, Tanya; Kicinski, Michal; Koehrer, Stefan; Kornblau, Steven M.; Kotecha, Rishi S.; Li, Chi-Kong; Liu, Yen-Chun; Locatelli, Franco; Luger, Selina M.; Paietta, Elisabeth M.; Manabe, Atsushi; Marquart, Hanne V.; Masetti, Riccardo; Maybury, Mellissa; Mazilier, Pauline; Meijerink, Jules P. P.; Mitchell, Sharnise; Miyamura, Takako; Moore, Andrew S.; Oshima, Koichi; Pawinska-Wasikowska, Katarzyna; Pieters, Rob; Prater, Mollie S.; Pruett-Miller, Shondra M.; Pui, Ching-Hon; Qu, Chunxu; Reiterova, Michaela; Reyes, Noemi; Roberts, Kathryn G.; Rowe, Jacob M.; Sato, Atsushi; Schmiegelow, Kjeld; Schrappe, Martin; Shen, Shuhong; Skoczen, Szymon; Spinelli, Orietta; Stary, Jan; Svaton, Michael; Takagi, Masatoshi; Takita, Junko; Tang, Yanjing; Teachey, David T.; Thomas, Paul G.; Tomizawa, Daisuke; Trka, Jan; Varotto, Elena; Vincent, Tiffaney L.; Yang, Jun J.; Yeoh, Allen E. J.; Zhou, Yinmei; Zimmermann, Martin; Inaba, Hiroto; Mullighan, Charles G. 分享 收藏
Association of leukemic molecular profile with efficacy of inotuzumab ozogamicin in adults with relapsed/refractory ALL Zhao, Yaqi; Laird, A. Douglas; Roberts, Kathryn G.; Yafawi, Rolla; Kantarjian, Hagop; DeAngelo, Daniel J.; Stelljes, Matthias; Liedtke, Michaela; Stock, Wendy; Goekbuget, Nicola; O'Brien, Susan; Jabbour, Elias; Cassaday, Ryan D.; Loyd, Melanie R.; Olsen, Scott; Neale, Geoffrey; Liu, Xueli; Vandendries, Erik; Advani, Anjali; Mullighan, Charles G. 分享 收藏
Enhanced Risk Stratification for Children and Young Adults with B-Cell Acute Lymphoblastic Leukemia: A Children's Oncology Group Report Delrocco, N. J.; Loh, M. L.; Borowitz, M. J.; Gupta, S.; Rabin, K. R.; Zweidler-McKay, P.; Maloney, K. W.; Mattano, L. A.; Larsen, E.; Angiolillo, A.; Schore, R. J.; Burke, M. J.; Salzer, W. L.; Wood, B. L.; Carroll, A. J.; Heerema, N. A.; Reshmi, S. C.; Gastier-Foster, J. M.; Harvey, R.; Chen, I. M.; Roberts, K. G.; Mullighan, C. G.; Willman, C.; Winick, N.; Carroll, W. L.; Rau, R. E.; Teachey, D. T.; Hunger, S. P.; Raetz, E. A.; Devidas, M.; Kairalla, J. A. 分享 收藏
Outcomes of adult patients with relapsed/refractory CRLF2 rearranged B-cell acute lymphoblastic leukemia Desikan, Sai Prasad; Senapati, Jayastu; Jabbour, Elias; Abuasab, Tareq; Short, Nicholas; Tang, Guilin; Wang, Sa; Kebriaei, Partow; Kadia, Tapan; Borthakur, Gautam; Ravandi, Farhad; Roberts, Kathryn; Mullighan, Charles; Konopleva, Marina; Kantarjian, Hagop; Jain, Nitin 分享 收藏
Whole genome sequencing provides comprehensive genetic testing in childhood B-cell acute lymphoblastic leukaemia Ryan, Sarra L.; Peden, John F.; Kingsbury, Zoya; Schwab, Claire J.; James, Terena; Polonen, Petri; Mijuskovic, Martina; Becq, Jenn; Yim, Richard; Cranston, Ruth E.; Hedges, Dale J.; Roberts, Kathryn G.; Mullighan, Charles G.; Vora, Ajay; Russell, Lisa J.; Bain, Robert; Moorman, Anthony V.; Bentley, David R.; Harrison, Christine J.; Ross, Mark T. 分享 收藏
Pharmacotypes across the genomic landscape of pediatric acute lymphoblastic leukemia and impact on treatment response Lee, Shawn H. R.; Yang, Wenjian; Gocho, Yoshihiro; John, August; Rowland, Lauren; Smart, Brandon; Williams, Hannah; Maxwell, Dylan; Hunt, Jeremy; Yang, Wentao; Crews, Kristine R. R.; Roberts, Kathryn G. G.; Jeha, Sima; Cheng, Cheng; Karol, Seth E. E.; Relling, Mary V. V.; Rosner, Gary L. L.; Inaba, Hiroto; Mullighan, Charles G. G.; Pui, Ching-Hon; Evans, William E. E.; Yang, Jun J. J. 分享 收藏
A convergent malignant phenotype in B-cell acute lymphoblastic leukemia involving the splicing factor SRRM1 Closa, Adria; Reixachs-Sole, Marina; Fuentes-Fayos, Antonio C.; Hayer, Katharina E.; Melero, Juan L.; Adriaanse, Fabienne R. S.; Bos, Romy S.; Torres-Diz, Manuel; Hunger, Stephen P.; Roberts, Kathryn G.; Mullighan, Charles G.; Stam, Ronald W.; Thomas-Tikhonenko, Andrei; Castano, Justo P.; Luque, Raul M.; Eyras, Eduardo 分享 收藏
NUDT21 limits CD19 levels through alternative mRNA polyadenylation in B cell acute lymphoblastic leukemia NUDT21通过替代mRNA聚腺苷酸化限制b细胞急性淋巴细胞白血病的CD19水平 Witkowski, Matthew T.; Lee, Soobeom; Wang, Eric; Lee, Anna K.; Talbot, Alexis; Ma, Chao; Tsopoulidis, Nikolaos; Brumbaugh, Justin; Zhao, Yaqi; Roberts, Kathryn G.; Hogg, Simon J.; Nomikou, Sofia; Ghebrechristos, Yohana E.; Thandapani, Palaniraja; Mullighan, Charles G.; Hochedlinger, Konrad; Chen, Weiqiang; Abdel-Wahab, Omar; Eyquem, Justin; Aifantis, Iannis 分享 收藏
Amino acid stress response genes promote L-asparaginase resistance in pediatric acute lymphoblastic leukemia Ferguson, Daniel C.; McCorkle, J. Robert; Barnett, Kelly R.; Bonten, Erik J.; Bergeron, Brennan P.; Bhattarai, Kashi Raj; Yang, Wenjian; Smith, Colton; Hansen, Baranda S.; Bajpai, Richa; Dong, Qian; Autry, Robert J.; Gocho, Yoshihiro; Diedrich, Jonathan D.; Crews, Kristine R.; Pruett-Miller, Shondra M.; Roberts, Kathryn G.; Stock, Wendy; Mullighan, Charles G.; Inaba, Hiroto; Jeha, Sima; Pui, Ching-Hon; Yang, Jun J.; Relling, Mary, V; Evans, William E.; Savic, Daniel 分享 收藏
Acute lymphoblastic leukemia displays a distinct highly methylated genome 急性淋巴细胞白血病显示出独特的高度甲基化的基因组 Hetzel, Sara; Mattei, Alexandra L.; Kretzmer, Helene; Qu, Chunxu; Chen, Xiang; Fan, Yiping; Wu, Gang; Roberts, Kathryn G.; Luger, Selina; Litzow, Mark; Rowe, Jacob; Paietta, Elisabeth; Stock, Wendy; Mardis, Elaine R.; Wilson, Richard K.; Downing, James R.; Mullighan, Charles G.; Meissner, Alexander 分享 收藏
ZNF384 Fusion Oncoproteins Drive Lineage Aberrancy in Acute Leukemia ZNF384融合癌蛋白在急性白血病中驱动谱系异常 Dickerson, Kirsten M.; Qu, Chunxu; Gao, Qingsong; Iacobucci, Ilaria; Gu, Zhaohui; Yoshihara, Hiroki; Backhaus, Emily A.; Chang, Yunchao; Janke, Laura J.; Xu, Beisi; Wu, Gang; Papachristou, Evangelia K.; D'Santos, Clive S.; Roberts, Kathryn G.; Mullighan, Charles G. 分享 收藏
Noncoding genetic variation in GATA3 increases acute lymphoblastic leukemia risk through local and global changes in chromatin conformation Yang, Hongbo; Zhang, Hui; Luan, Yu; Liu, Tingting; Yang, Wentao; Roberts, Kathryn G.; Qian, Mao-xiang; Zhang, Bo; Yang, Wenjian; Perez-Andreu, Virginia; Xu, Jie; Iyyanki, Sriranga; Kuang, Da; Stasiak, Lena A.; Reshmi, Shalini C.; Gastier-Foster, Julie; Smith, Colton; Pui, Ching-Hon; Evans, William E.; Hunger, Stephen P.; Platanias, Leonidas C.; Relling, Mary, V; Mullighan, Charles G.; Loh, Mignon L.; Yue, Feng; Yang, Jun J. 分享 收藏
The impact of genetic ancestry on the biology and prognosis of childhood acute lymphoblastic leukemia Lee, Shawn; Antillon, Federico; Pei, Deqing; Yang, Wenjian; Roberts, Kathryn G.; Li, Zhenhua; Devidas, Meenakshi; Yang, Wentao; Najera, Cesar; Lin, Hai Peng; Tan, Ah Moy; Ariffin, Hany; Cheng, Cheng; Evans, William E.; Hunger, Stephen P.; Jeha, Sima; Mullighan, Charles G.; Loh, Mignon L.; Yeoh, Allen Ej; Pui, Ching-Hon; Yang, Jun J. 分享 收藏
Interleukin-7 receptor α mutational activation can initiate precursor B-cell acute lymphoblastic leukemia Almeida, Afonso R. M.; Neto, Joao L.; Cachucho, Ana; Euzebio, Mayara; Meng, Xiangyu; Kim, Rathana; Fernandes, Marta B.; Raposo, Beatriz; Oliveira, Mariana L.; Ribeiro, Daniel; Fragoso, Rita; Zenatti, Priscila P.; Soares, Tiago; de Matos, Mafalda R.; Correa, Juliana Ronchi; Duque, Mafalda; Roberts, Kathryn G.; Gu, Zhaohui; Qu, Chunxu; Pereira, Clara; Pyne, Susan; Pyne, Nigel J.; Barreto, Vasco M.; Bernard-Pierrot, Isabelle; Clappier, Emannuelle; Mullighan, Charles G.; Grosso, Ana R.; Yunes, J. Andres; Barata, Joao T. 分享 收藏
Enhancer Hijacking Drives Oncogenic BCL11B Expression in Lineage-Ambiguous Stem Cell Leukemia Montefiori, Lindsey E.; Bendig, Sonja; Gu, Zhaohui; Chen, Xiaolong; Polonen, Petri; Ma, Xiaotu; Murison, Alex; Zeng, Andy; Garcia-Prat, Laura; Dickerson, Kirsten; Iacobucci, Ilaria; Abdelhamed, Sherif; Hiltenbrand, Ryan; Mead, Paul E.; Mehr, Cyrus M.; Xu, Beisi; Cheng, Zhongshan; Chang, Ti-Cheng; Westover, Tamara; Ma, Jing; Stengel, Anna; Kimura, Shunsuke; Qu, Chunxu; Valentine, Marcus B.; Rashkovan, Marissa; Luger, Selina; Litzow, Mark R.; Rowe, Jacob M.; den Boer, Monique L.; Wang, Victoria; Yin, Jun; Kornblau, Steven M.; Hunger, Stephen P.; Loh, Mignon L.; Pui, Ching-Hon; Yang, Wenjian; Crews, Kristine R.; Roberts, Kathryn G.; Yang, Jun J.; Relling, Mary, V; Evans, William E.; Stock, Wendy; Paietta, Elisabeth M.; Ferrando, Adolfo A.; Zhang, Jinghui; Kern, Wolfgang; Haferlach, Torsten; Wu, Gang; Dick, John E.; Klco, Jeffery M.; Haferlach, Claudia; Mullighan, Charles G. 分享 收藏
Clinical Significance of novel Subtypes of Acute Lymphoblastic Leukemia in the Context of Minimal Residual Disease-Directed Therapy 微小残留病导向治疗背景下急性淋巴细胞白血病新亚型的临床意义 Jeha, Sima; Choi, John; Roberts, Kathryn G.; Pei, Deqing; Coustan-Smith, Elaine; Inaba, Hiroto; Rubnitz, Jeffrey E.; Ribeiro, Raul C.; Gruber, Tanja A.; Raimondi, Susana C.; Karol, Seth E.; Qu, Chunxu; Brady, Samuel W.; Gu, Zhaohui; Yang, Jun J.; Cheng, Cheng; Downing, James R.; Evans, Williams E.; Relling, Mary, V; Campana, Dario; Mullighan, Charles G.; Pui, Ching-Hon 分享 收藏
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