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Selumetinib in Combination with Anti Retroviral Therapy in HIV-associated Kaposi sarcoma (SCART): an open-label, multicentre, phase I/II trial Young, Robin J.; Kirkham, Amanda; Savage, Joshua; Gaskell, Charlotte; Johnson, Sarah; Dockrell, David H.; Bower, Mark; Westwell, Sarah; Bowman, Christine; Leahy, Michael; Woll, Penella; Billingham, Lucinda 分享 收藏
MONOGERM, A NOVEL PROOF-OF-PRINCIPLE BAYESIAN PHASE II TRIAL DESIGN OF CARBOPLATIN OR VINBLASTINE MONOTHERAPY INDUCTION PRIOR TO RADIOTHERAPY FOR INTRACRANIAL GERMINOMA Kirton, Laura; Apps, John; Lawson, Anna; Arvanitis, Theodoros; Mitra, Dipayan; Gagan, Richard; Patel, Hiten; Peet, Andrew; Fern, Lorna; Williams, Emma; Coleman, Nicholas; Ajithkumar, Thankamma; Bison, Brigitte; Veal, Gareth; Stark, Daniel; Morana, Giovanni; Nicholson, James; Billingham, Lucinda; Murray, Matthew 分享 收藏
MONOGERM, A NOVEL PROOF-OF-PRINCIPLE BAYESIAN PHASE II TRIAL DESIGN OF CARBOPLATIN OR VINBLASTINE MONOTHERAPY INDUCTION PRIOR TO RADIOTHERAPY FOR INTRACRANIAL GERMINOMA Kirton, Laura; Apps, John R.; Lawson, Anna; Arvanitis, Theodoros; Mitra, Dipayan; Gagen, Richard; Patel, Hiten; Peet, Andrew; Fern, Lorna; Williams, Emma; Coleman, Nicholas; Ajithkumar, Thankamma; Bison, Brigitte; Veal, Gareth; Stark, Daniel P.; Morana, Giovanni; Nicholson, James C.; Billingham, Lucinda; Murray, Matthew J. 分享 收藏
Multi-omic immunophenotyping to identify predictors of mRNA vaccine responsiveness in immunocompromised individuals Murray, Sam; Meacham, Georgina; Irwin, Sophie; Rao, Vishal; Rolt, Jordan; Dimitriadis, Stavros; Dooley, Kyla; Heslington, Amelia; Goodyear, Carl; Siebert, Stefan; Mcinnes, Iain; Willicombe, Michelle; Thomas, David; Billingham, Lucinda; Kearns, Pamela; Marjot, Thomas; Kronsteiner, Barbara 分享 收藏
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Histology independent drug development - Is this the future for cancer drugs? Billingham, Lucinda; Brown, Lynn; Framke, Theodor; Greystoke, Alastair; Hovig, Eivind; Mathur, Siddhartha; Page, Philippe; Pean, Elias; van Doorn-Khosrovani, Sahar Barjesteh van Waalwijk; Vonk, Richardus; Wissink, Sacha; Zander, Hilke; Plummer, Ruth 分享 收藏
A randomised phase II trial of temozolomide with or without cannabinoids in patients with recurrent glioblastoma (ARISTOCRAT): protocol for a multi-centre, double-blind, placebo-controlled trial 替莫唑胺联合或不联合大麻素治疗复发性胶质母细胞瘤患者的随机II期试验 (ARISTOCRAT): 多中心、双盲、安慰剂对照试验方案 Bhaskaran, Divyalakshmi; Savage, Joshua; Patel, Amit; Collinson, Fiona; Mant, Rhys; Boele, Florien; Brazil, Lucy; Meade, Sara; Buckle, Peter; Lax, Sian; Billingham, Lucinda; Short, Susan C. 分享 收藏
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Selenium and Vitamin E for Prevention of Non-Muscle-Invasive Bladder Cancer Recurrence and Progression A Randomized Clinical Trial 硒和维生素e预防非肌层浸润性膀胱癌复发和进展的随机临床试验 Bryan, Richard T.; Pirrie, Sarah J.; Abbotts, Ben; Maycock, Shanna; During, Vinnie; Lewis, Carolyn; Grant, Margaret; Bird, Deborah; Devall, Adam J.; Wallace, D. Michael A.; James, Nicholas D.; Billingham, Lucinda J.; Zeegers, Maurice P.; Cheng, K. K. 分享 收藏
DETERMINE: A pioneering UK precision medicine trial for rare cancers 确定: 英国针对罕见癌症的开创性精密医学试验 Middleton, G.; Marshall, L.; Billingham, L.; Duffus, K. D.; Greystoke, A.; Carter, L.; Forster, M. D.; Cook, N.; Hargrave, D.; Danson, S.; Roxburgh, P.; Beggs, A. D.; Chaturvedi, A.; Chesler, L.; Sarmiento-Castro, A.; Dive, C.; Rothwell, D.; Gath, J.; Halford, S.; Krebs, M. G. 分享 收藏
Axitinib in patients with advanced/metastatic soft tissue sarcoma (Axi-STS): an open-label, multicentre, phase II trial in four histological strata Woll, Penella J.; Gaunt, Piers; Gaskell, Charlotte; Young, Robin; Benson, Charlotte; Judson, Ian R.; Seddon, Beatrice M.; Marples, Maria; Ali, Nasim; Strauss, Sandra J.; Lee, Alexander; Hughes, Ana; Kaur, Baljit; Hughes, David; Billingham, Lucinda 分享 收藏
Technical development and validation of a clinically applicable microenvironment classifier as a biomarker of tumour hypoxia for soft tissue sarcoma Forker, Laura J.; Bibby, Becky; Yang, Lingjian; Lane, Brian; Irlam, Joely; Mistry, Hitesh; Khan, Mairah; Valentine, Helen; Wylie, James; Shenjere, Patrick; Leahy, Michael; Gaunt, Piers; Billingham, Lucinda; Seddon, Beatrice M.; Grimer, Rob; Robinson, Martin; Choudhury, Ananya; West, Catharine 分享 收藏
Venetoclax combined with low dose cytarabine compared to standard of care intensive chemotherapy for the treatment of favourable risk adult acute myeloid leukaemia (VICTOR): Study protocol for an international, open-label, multicentre, molecularly-guided randomised, phase II trial Dillon, Richard; Maycock, Shanna; Jackson, Aimee; Fox, Sonia; Freeman, Sylvie; Craddock, Charles; Thomas, Catherine; Homer, Emma; Leahy, Jane; Mamwell, Anna; Potter, Nicola; Russell, Nigel; Wei, Andrew; Ommen, Hans Beier; Hemmaway, Claire; Knapper, Steve; Billingham, Lucinda 分享 收藏
Assessing nivolumab in class II expressing microsatellite stable (pMMR) colorectal cancer (CRC): Results of the ANICCA-Class II trial Middleton, G.; Liu, W.; Savage, J.; Bridgewater, J. A.; Ross, P.; Saunders, M. P.; Plummer, R.; Clive, S.; Coyle, V.; Thomas, A.; Taniere, P.; Billingham, L. 分享 收藏
Outcomes from a mechanistic biomarker multi-arm and randomised study of liposomal MTP-PE (Mifamurtide) in metastatic and/or recurrent osteosarcoma (EuroSarc-Memos trial) Barnes, David J.; Dutton, Peter; Bruland, Oyvind; Gelderblom, Hans; Faleti, Ade; Buhnemann, Claudia; van Maldegem, Annemiek; Johnson, Hannah; Poulton, Lisa; Love, Sharon; Tiemeier, Gesa; van Beelen, Els; Herbschleb, Karin; Haddon, Caroline; Billingham, Lucinda; Bradley, Kevin; Ferrari, Stefano; Palmerini, Emanuela; Picci, Piero; Dirksen, Uta; Strauss, Sandra J.; Hogendoorn, Pancras C. W.; Buddingh, Emmeline; Blay, Jean-Yves; Cleton-Jansen, Anne Marie; Hassan, Andrew Bassim 分享 收藏
Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer Chrysostomou, Stelios; Roy, Rajat; Prischi, Filippo; Thamlikitkul, Lucksamon; Chapman, Kathryn L.; Mufti, Uwais; Peach, Robert; Ding, Laifeng; Hancock, David; Moore, Christopher; Molina-Arcas, Miriam; Mauri, Francesco; Pinato, David J.; Abrahams, Joel M.; Ottaviani, Silvia; Castellano, Leandro; Giamas, Georgios; Pascoe, Jennifer; Moonamale, Devmini; Pirrie, Sarah; Gaunt, Claire; Billingham, Lucinda; Steven, Neil M.; Cullen, Michael; Hrouda, David; Winkler, Mathias; Post, John; Cohen, Philip; Salpeter, Seth J.; Bar, Vered; Zundelevich, Adi; Golan, Shay; Leibovici, Dan; Lara, Romain; Klug, David R.; Yaliraki, Sophia N.; Barahona, Mauricio; Wang, Yulan; Downward, Julian; Skehel, J. Mark; Ali, Maruf M. U.; Seckl, Michael J.; Pardo, Olivier E. 分享 收藏
Beta-hydroxy beta-methylbutyrate/arginine/glutamine (HMB/Arg/Gln) supplementation to improve the management of cachexia in patients with advanced lung cancer: an open-label, multicentre, randomised, controlled phase II trial (NOURISH) Pascoe, Jennifer; Jackson, Aimee; Gaskell, Charlotte; Gaunt, Claire; Thompson, Joyce; Billingham, Lucinda; Steven, Neil 分享 收藏