Nigel J. Pyne - Publications, H-index & Citations

Nigel J. Pyne

university of strathclyde

58H指数

233论文数

1.2W被引数

收录论文 110

发表时间

The Concise Guide to PHARMACOLOGY 2023/24: Enzymes

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2023-12-20

172

OAAI

Alexander, Stephen P. H.; Fabbro, Doriano; Kelly, Eamonn; Mathie, Alistair A.; Peters, John A.; Veale, Emma L.; Armstrong, Jane F.; Faccenda, Elena; Harding, Simon D.; Davies, Jamie A.; Annett, Stephanie; Boison, Detlev; Burns, Kathryn Elisa; Dessauer, Carmen; Gertsch, Jurg; Helsby, Nuala Ann; Izzo, Angelo A.; Ostrom, Rennolds; Papapetropoulos, Andreas; Pyne, Nigel J.; Pyne, Susan; Robson, Tracy; Seifert, Roland; Stasch, Johannes-Peter; Szabo, Csaba; van der Stelt, Mario; van der Vliet, Albert; Watts, Val; Wong, Szu Shen

Sphingosine Kinase 1 Induces Tolerance to Human Epidermal Growth Factor Receptor 2 and Prevents Formation of a Migratory Phenotype in Response to Sphingosine 1-Phosphate in Estrogen Receptor-Positive Breast Cancer Cells

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

OAAI

Long, Jaclyn S.; Edwards, Joanne; Watson, Carol; Tovey, Sian; Mair, Kirsty M.; Schiff, Rachel; Natarajan, Viswanathan; Pyne, Nigel J.; Pyne, Susan

Native and Polyubiquitinated Forms of Dihydroceramide Desaturase Are Differentially Linked to Human Embryonic Kidney Cell Survival

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-03

OAAI

Alsanafi, Mariam; Kelly, Samuel L.; Jubair, Karawan; McNaughton, Melissa; Tate, Rothwelle J.; Merrill, Alfred H., Jr.; Pyne, Susan; Pyne, Nigel J.

Interleukin-7 receptor α mutational activation can initiate precursor B-cell acute lymphoblastic leukemia

NATURE COMMUNICATIONS

IF15.7

2021-12-14

OAAI

Almeida, Afonso R. M.; Neto, Joao L.; Cachucho, Ana; Euzebio, Mayara; Meng, Xiangyu; Kim, Rathana; Fernandes, Marta B.; Raposo, Beatriz; Oliveira, Mariana L.; Ribeiro, Daniel; Fragoso, Rita; Zenatti, Priscila P.; Soares, Tiago; de Matos, Mafalda R.; Correa, Juliana Ronchi; Duque, Mafalda; Roberts, Kathryn G.; Gu, Zhaohui; Qu, Chunxu; Pereira, Clara; Pyne, Susan; Pyne, Nigel J.; Barreto, Vasco M.; Bernard-Pierrot, Isabelle; Clappier, Emannuelle; Mullighan, Charles G.; Grosso, Ana R.; Yunes, J. Andres; Barata, Joao T.

Validation of highly selective sphingosine kinase 2 inhibitors SLM6031434 and HWG-35D as effective anti-fibrotic treatment options in a mouse model of tubulointerstitial fibrosis 在肾小管间质纤维化小鼠模型中验证高选择性鞘氨醇激酶2抑制剂SLM6031434和HWG-35D作为有效的抗纤维化治疗选择

CELLULAR SIGNALLING

IF3.7

2021-03-01

OAAI

Schwalm, Stephanie; Beyer, Sandra; Hafizi, Redona; Trautmann, Sandra; Geisslinger, Gerd; Adams, David R.; Pyne, Susan; Pyne, Nigel; Schaefer, Liliana; Huwiler, Andrea; Pfeilschifter, Josef

A new model for regulation of sphingosine kinase 1 translocation to the plasma membrane in breast cancer cells

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-01-01

OAAI

Brown, Ryan D. R.; Veerman, Ben E. P.; Oh, Jeongah; Tate, Rothwelle J.; Torta, Federico; Cunningham, Margaret R.; Adams, David R.; Pyne, Susan; Pyne, Nigel J.

Structure-function analysis of lipid substrates and inhibitors of sphingosine kinases

CELLULAR SIGNALLING

IF3.7

2020-12-01

OAAI

Adams, David R.; Pyne, Susan; Pyne, Nigel J.

Recent advances in the role of sphingosine 1-phosphate in cancer 1-磷酸鞘氨醇在肿瘤中的作用研究进展

FEBS LETTERS

IF3

2020-10-04

OAAI

Pyne, Nigel J.; Pyne, Susan

Sphingosine Kinase 1 Regulates the Survival of Breast Cancer Stem Cells and Non-stem Breast Cancer Cells by Suppression of STAT1

CELLS

IF5.2

2020-04-04

OAAI

Hii, Ling-Wei; Chung, Felicia Fei-Lei; Mai, Chun Wai; Yee, Zong Yang; Chan, Hong Hao; Raja, Vijay Joseph; Dephoure, Noah Elias; Pyne, Nigel J.; Pyne, Susan; Leong, Chee-Onn

The regulation of p53, p38 MAPK, JNK and XBP-1s by sphingosine kinases in human embryonic kidney cells

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

IF3.3

2020-04-01

OAAI

Alsanafi, Mariam; Kelly, Samuel L.; McNaughton, Melissa; Merrill, Alfred H., Jr.; Pyne, Nigel J.; Pyne, Susan

Short Periods of Hypoxia Upregulate Sphingosine Kinase 1 and Increase Vasodilation of Arteries to Sphingosine 1-Phosphate (S1P) via S1P3

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2019-10-01

OAAI

Alganga, H.; Almabrouk, T. A. M.; Katwan, O. J.; Daly, C. J.; Pyne, S.; Pyne, N. J.; Kennedy, S.

Small-molecule allosteric activators of PDE4 long form cyclic AMP phosphodiesterases

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2019-06-17

OAAI

Omar, Faisa; Findlay, Jane E.; Carfray, Gemma; Allcock, Robert W.; Jiang, Zhong; Moore, Caitlin; Muir, Amy L.; Lannoy, Morgane; Fertig, Bracy A.; Mai, Deborah; Day, Jonathan P.; Bolger, Graeme; Baillie, George S.; Schwiebert, Erik; Klussmann, Enno; Pyne, Nigel J.; Ong, Albert C. M.; Bowers, Keith; Adam, Julia M.; Adams, David R.; Houslay, Miles D.; Henderson, David J. P.

Ceramide and sphingosine 1-phosphate in adipose dysfunction

PROGRESS IN LIPID RESEARCH

IF14.9

2019-04-01

OAAI

Fang, Zijian; Pyne, Susan; Pyne, Nigel J.

Topographical Mapping of Isoform-Selectivity Determinants for J-Channel-Binding Inhibitors of Sphingosine Kinases 1 and 2

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2019-03-19

OAAI

Adams, David R.; Tawati, Salha; Berretta, Giacomo; Rivas, Paula Lopez; Baiget, Jessica; Jiang, Zhong; Alsfouk, Aisha; Mackay, Simon P.; Pyne, Nigel J.; Pyne, Susan

Requirement for sphingosine kinase 1 in mediating phase 1 of the hypotensive response to anandamide in the anaesthetised mouse

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2019-01-01

OAAI

Greig, Fiona H.; Nather, Katrin; Ballantyne, Margaret D.; Kazi, Zeshan H.; Alganga, Husam; Ewart, Marie-Ann; Zaborska, Karolina E.; Fertig, Bracy; Pyne, Nigel J.; Pyne, Susan; Kennedy, Simon

Does the Sphingosine 1-Phosphate Receptor-1 Provide a Better or Worse Prognostic Outcome for Breast Cancer Patients?1-磷酸鞘氨醇受体-1是否为乳腺癌患者提供更好或更差的预后结果？

FRONTIERS IN ONCOLOGY

IF3.3

2018-09-27

OAAI

Pyne, Nigel J.; Pyne, Susan

Cellular Signalling - Special issue to celebrate 75th birthday of Prof. Robert J. Lefkowitz

CELLULAR SIGNALLING

IF3.7

2018-01-01

OAAI

Shukla, Arun K.; Pyne, Nigel J.