未登录 8 MonoGerm: Phase II trial of carboplatin or vinblastine monotherapy prior to radiotherapy for intracranial germinoma, using novel proof-of-principle Bayesian design 8 MonoGerm：颅内生殖细胞瘤在放疗前使用卡铂或长春碱单药治疗的II期临床试验，采用新型原理验证贝叶斯设计 Laura Kirton, Dr; John Apps; Anna Lawson, Professor; Theodoros Arvanitis, Dr; Dipayan Mitra, Dr; Richard Gagen, Dr; Hiten Patel, Professor; Andrew Peet, Dr; Lorna Fern, Dr; Emma Williams, Professor; Nicholas Coleman, Dr; Thankamma Ajithkumar, Dr; Brigitte Bison, Professor; Gareth Veal, Professor; Daniel Stark, Dr; Shivani Bailey, Dr; Cinzia Scarpini, Professor; Giovanni Morana, Dr; James Nicholson, Professor; Lucinda Billingham, Professor; Matthew Murray 分享 收藏
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Lingual hamartoma-like lipoblastoma: the diagnostic value of routine whole-genome sequencing Kan, Sheng-Yuan; Ferro, Ashley; Watkins, James A.; Behjati, Sam; Murray, Matthew J.; Coleman, Nicholas; Roberts, Thomas; Cross, Justin; Trotman, Jamie; Tarpey, Patrick; Hook, C. Elizabeth; Cameron, Malcolm; Tadross, John A. 分享 收藏
MONOGERM, A NOVEL PROOF-OF-PRINCIPLE BAYESIAN PHASE II TRIAL DESIGN OF CARBOPLATIN OR VINBLASTINE MONOTHERAPY INDUCTION PRIOR TO RADIOTHERAPY FOR INTRACRANIAL GERMINOMA Kirton, Laura; Apps, John; Lawson, Anna; Arvanitis, Theodoros; Mitra, Dipayan; Gagan, Richard; Patel, Hiten; Peet, Andrew; Fern, Lorna; Williams, Emma; Coleman, Nicholas; Ajithkumar, Thankamma; Bison, Brigitte; Veal, Gareth; Stark, Daniel; Morana, Giovanni; Nicholson, James; Billingham, Lucinda; Murray, Matthew 分享 收藏
METASTATIC BIFOCAL GERMINOMA: A CASE HIGHLIGHTING DRAMATIC EARLY RADIOLOGICAL RESPONSE TO STEROIDS AND REBOUND FOLLOWING DISCONTINUATION, AND THE UTILITY OF CIRCULATING MIR-371A-3P QUANTIFICATION AND VINBLASTINE MONOTHERAPY PRIOR TO DEFINITIVE CRANIOSPINAL IRRADIATION Scarpini, Cinzia; Ward, Dawn; Phyu, Poe; Jalloh, Ibrahim; Thorp, Nicky; Fisher, Benjamin; Hendriks, Emile; Salisbury, Lyndsay; Nicholson, James; Ajithkumar, Thankamma; Horan, Gail; Burke, Amos; Coleman, Nicholas; Allinson, Kieren; Murray, Matthew 分享 收藏
Replenishing co-downregulated miR-100-5p and miR-125b-5p in malignant germ cell tumors causes growth inhibition through cell cycle disruption Ferraresso, Marta; Bailey, Shivani; Alonso-Crisostomo, Luz; Ward, Dawn; Panayi, Christos; Scurlock, Zachary G. L.; Saini, Harpreet K.; Smith, Stephen P.; Nicholson, James C.; Enright, Anton J.; Scarpini, Cinzia G.; Coleman, Nicholas; Murray, Matthew J. 分享 收藏
Molecular analysis improves the diagnosis of young people with renal tumors Leiter, Sarah M.; Guobadia, Aisosa; Fleming, Ben; Ajithkumar, Thankamma; Armitage, James; Armstrong, Ruth; Burke, G. A. Amos; Burns, Charlotte; Chowdhury, Tanzina; Coleman, Nicholas; Hatcher, Helen; Horan, Gail; Howell, Lisa; Long, Anna-May; McDonald, Sarah; Mitchell, Thomas J.; Nicholson, James C.; Roberts, Thomas; Stewart, Grant D.; Tadross, John A.; Tarpey, Patrick; Trayers, Claire; Trotman, Jamie; Watkins, James; Warren, Anne Y.; Vujanic, Godran; Hook, C. Elizabeth; Behjati, Sam; Murray, Matthew J. 分享 收藏
Whole genome sequencing provides practice-changing benefits when performed on consecutive, unselected children with suspected cancer Hodder, Angus; Leiter, Sarah M.; Kennedy, Jonathan; Addy, Dilys; Ahmed, Munaza; Ajithkumar, Thankamma; Allinson, Kieren; Ancliff, Phil; Bailey, Shivani; Barnard, Gemma; Burke, G. A. Amos; Burns, Charlotte; Cano-Flanagan, Julian; Chalker, Jane; Coleman, Nicholas; Cheng, Danny; Clinch, Yasmin; Dryden, Caryl; Ghorashian, Sara; Griffin, Blanche; Horan, Gail; Hubank, Michael; May, Phillippa; McDerra, Joanna; Nagrecha, Rajvi; Nicholson, James; O'Connor, David; Pavasovic, Vesna; Quaegebeur, Annelies; Rao, Anupama; Roberts, Thomas; Samarasinghe, Sujith; Stasevich, Iryna; Tadross, John A.; Trayers, Claire; Trotman, Jamie; Vora, Ajay; Watkins, James; Chitty, Lyn S.; Bowdin, Sarah; Armstrong, Ruth; Murray, Matthew J.; Hook, Catherine E.; Tarpey, Patrick; Vedi, Aditi; Bartram, Jack; Behjati, Sam 分享 收藏
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Benefits for children with suspected cancer from routine whole-genome sequencing Hodder, Angus; Leiter, Sarah M.; Kennedy, Jonathan; Addy, Dilys; Ahmed, Munaza; Ajithkumar, Thankamma; Allinson, Kieren; Ancliff, Phil; Bailey, Shivani; Barnard, Gemma; Burke, G. A. Amos; Burns, Charlotte; Cano-Flanagan, Julian; Chalker, Jane; Coleman, Nicholas; Cheng, Danny; Clinch, Yasmin; Dryden, Caryl; Ghorashian, Sara; Griffin, Blanche; Horan, Gail; Hubank, Michael; May, Phillippa; McDerra, Joanna; Nagrecha, Rajvi; Nicholson, James; O'Connor, David; Pavasovic, Vesna; Quaegebeur, Annelies; Rao, Anupama; Roberts, Thomas; Samarasinghe, Sujith; Stasevich, Iryna; Tadross, John A.; Trayers, Claire; Trotman, Jamie; Vora, Ajay; Watkins, James; Chitty, Lyn S.; Bowdin, Sarah; Armstrong, Ruth; Murray, Matthew J.; Hook, Catherine E.; Tarpey, Patrick; Vedi, Aditi; Bartram, Jack; Behjati, Sam 分享 收藏
MONOGERM, A NOVEL PROOF-OF-PRINCIPLE BAYESIAN PHASE II TRIAL DESIGN OF CARBOPLATIN OR VINBLASTINE MONOTHERAPY INDUCTION PRIOR TO RADIOTHERAPY FOR INTRACRANIAL GERMINOMA Kirton, Laura; Apps, John R.; Lawson, Anna; Arvanitis, Theodoros; Mitra, Dipayan; Gagen, Richard; Patel, Hiten; Peet, Andrew; Fern, Lorna; Williams, Emma; Coleman, Nicholas; Ajithkumar, Thankamma; Bison, Brigitte; Veal, Gareth; Stark, Daniel P.; Morana, Giovanni; Nicholson, James C.; Billingham, Lucinda; Murray, Matthew J. 分享 收藏
Targeting oncogenic microRNAs from the miR-371∼373 and miR-302/367 clusters in malignant germ cell tumours causes growth inhibition through cell cycle disruption (vol 129, pg 1451, 2023) Bailey, Shivani; Ferraresso, Marta; Alonso-Crisostomo, Luz; Ward, Dawn; Smith, Stephen; Nicholson, James C.; Saini, Harpreet; Enright, Anton J.; Scarpini, Cinzia G.; Coleman, Nicholas; Murray, Matthew J. 分享 收藏
Targeting oncogenic microRNAs from the miR-371∼373 and miR-302/267 clusters in malignant germ cell tumours causes growth inhibition through cell cycle disruption Bailey, Shivani; Ferraresso, Marta; Alonso-Crisostomo, Luz; Ward, Dawn; Smith, Stephen; Nicholson, James C.; Saini, Harpreet; Enright, Anton J.; Scarpini, Cinzia G.; Coleman, Nicholas; Murray, Matthew J. 分享 收藏
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Testicular germ cell tumour cells release microRNA-containing extracellular vesicles that induce phenotypic and genotypic changes in cells of the tumour microenvironment 睾丸生殖细胞肿瘤细胞释放含有microRNA的细胞外囊泡，诱导肿瘤微环境细胞的表型和基因型变化 Alonso-Crisostomo, Luz; Trendell, Jennifer; Ferraresso, Marta; Bailey, Shivani; Ward, Dawn; Scurlock, Zachary G. L.; Wenlock, Stephanie C.; Bastos, Carlos A. P.; Jugdaohsingh, Ravin; Faria, Nuno J.; Enright, Anton J.; Scarpini, Cinzia G.; Coleman, Nicholas; Murray, Matthew J. 分享 收藏
Refining the serum miR-371a-3p test for viable germ cell tumor detection Lafin, John T.; Scarpini, Cinzia G.; Amini, Armon; Konneh, Bendu; Howard, Jeffrey M.; Gerald, Thomas; Nuno, Michelle; Piao, Jin; Savelyeva, Anna; Wang, Zhaohui; Gagan, Jeffrey; Jia, Liwei; Lewis, Cheryl M.; Murray, Sarah; Sawa, Yun C.; Margulis, Vitaly; Woldu, Solomon L.; Strand, Douglas W.; Coleman, Nicholas; Amatruda, James F.; Frazier, A. Lindsay; Murray, Matthew J.; Bagrodia, Aditya 分享 收藏
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