Brendan W. Wren - Publications, H-index & Citations

Brendan W. Wren

christian medical college & hospital (cmch) vellore

85H指数

480论文数

2.8W被引数

收录论文 167

发表时间

Development and evaluation of a dual-target glycoconjugate against Shigella sonnei 针对志贺氏菌 Sonnei 的双靶点糖缀合物的开发与评价

Frontiers in Immunology

IF5.9

2026-09-22

OAAI

CL Catherine L. Hall; TL Tom L. Flood; SC Simon Clare; KH Katherine Harcourt; EJ Emily J. Kay; SB Stephen Baker; BW Brendan W. Wren

High-throughput antigen discovery using Functional Genomic Vaccinology (FGV) identifies protective Streptococcus pneumoniae vaccine candidates 利用功能基因组学疫苗学（FGV）进行高通量抗原发现，鉴定出具有保护性的肺炎链球菌疫苗候选物

Nature Communications

IF15.7

2026-07-21

OAAI

Giuseppe Ercoli; Elisa Ramos-Sevillano; Samantha Palethorpe; Trisha Kerai; Timothy Scott; Rafael R. de Assis; Aarti Jain; Algis Jasinskas; Rie Nakajima; Jiin Felgner; Stephanie W. Lo; Brendan W. Wren; Philip Felgner; Jeremy S. Brown

Geographic clustering and population structures of Campylobacter jejuni and Campylobacter coli in South and Southeast Asian poultry systems 南亚和东南亚家禽体系中空肠弯曲杆菌和大肠弯曲杆菌的地理聚集与种群结构

Microbial Genomics

IF4

2026-05-01

PREAI

Lehri, Burhan; Nhung, Le Thi Hong; Ghosh, Keya; Logno, Tahia Ahmed; Hasan, Mahamudul; Weerasooriya, G.; Priyantha, M. A. R.; De Alwis, P. S.; Janagaraj, Venkateshprabhu; Manoharan, Zayina Zondervenni; Dantroliya, Sadiq; Pandit, Ramesh; Joshi, Chaitanya; Huong, Luu Quynh; Anandachitra, M.; Joshi, Madhvi; Mahmud, Rashed; Ngoc, Pham Thi; Coombs, Archibald; Li, Ying Ying Chrystal; Ramachandra, Mahati; Butt, Saira; Ronald, Samuel M.; Conan, Anne; Biswas, Paritosh Kumar; Samad, Mohammed Abdus; Kalupahana, Ruwani; Ajjampur, Sitara Swarna Rao; Fournie, Guillaume; Wren, Brendan W.; Tomley, Fiona; Blake, Damer P.; Stabler, Richard A.

A two-step actin-mediated strategy enables Campylobacter jejuni to promote mitochondrial aggregation and iron homeostasis, for intracellular survival and persistence 一种两步肌动蛋白介导的策略使弯曲杆菌促进线粒体聚集和铁稳态，以实现细胞内生存和持续存在。

Communications Biology

IF5.1

2026-02-14

OAAI

Fauzy Nasher; Brendan W. Wren

The unfolded protein response is a critical mediator in Campylobacter jejuni pathogenesis and host defence 未折叠蛋白反应是 *Campylobacter jejuni* 病原性和宿主防御的关键介导因子。

Microbes and Infection

IF2.7

2025-10-28

OAAI

Geunhye Hong; Zahra Omole; Cadi Davies; Janie Liaw; Anna D. Grabowska; Barbara Canonico; Nicolae Corcionivoschi; Brendan W. Wren; Ezra Aksoy; Nick Dorrell; Abdi Elmi; Ozan Gundogdu

Surface visualisation of bacterial biofilms using neutral atom microscopy 利用中性原子显微镜对细菌生物膜进行表面可视化

Journal of Microscopy

IF1.9

2025-10-01

OAAI

von Jeinsen, Nick A.; Ward, David J.; Bergin, Matthew; Lambrick, Sam M.; Williamson, David M.; Langford, Richard M.; Dawson, Lisa F.; Rana, Vibhuti; Shivaswamy, Sushma; Zhou, Xuening; Mikesh, Michelle; Gordon, Vernita D.; Wren, Brendan W.; Brown, Katherine A.; Dastoor, Paul C.

Host-Derived Reactive Oxygen Species in the Gut Epithelium: Defence Mechanism and Target of Bacterial Subversion 宿源反应性氧物质在肠道上皮中的作用：防御机制与细菌操纵的靶点

Antioxidants 2025, Vol. 14, Page 1156

IF6.6

2025-09-26

OAAI

Pranaya Kansakar; Subhadeep Gupta; Amirul Islam Mallick; Brendan W. Wren; Ezra Aksoy; Abdi Elmi; Ozan Gundogdu

Recent Advances in Bioconjugate Vaccine Development 生物缀合物疫苗开发的最新进展

Vaccines 2025, Vol. 13, Page 703

IF3.4

2025-08-23

PREAI

Brendan W. Wren; Catherine L. Hall; Vanessa S. Terra; Mark A. Harrison; Elizabeth Atkins; Fauzy Nasher; Ian J. Passmore

Opportunities and challenges for the adoption of novel platform technologies to develop veterinary bacterial vaccines 新型平台技术在兽用细菌疫苗开发中的应用机遇与挑战

VACCINE

IF3.5

2025-04-01

OAAI

Entrican, Gary; Bredell, Helba; Charlier, Johannes; Cunningham, Adam F.; Jarvis, Michael A.; Wood, Paul R.; Wren, Brendan W.; Hope, Jayne C.

Modular Combinatorial DNA Assembly of Group B Streptococcus Capsular Polysaccharide Biosynthesis Pathways to Expediate the Production of Novel Glycoconjugate Vaccines 模块化组合DNA组装法用于构建B族链球菌荚膜多糖生物合成途径，以加速新型糖蛋白偶联疫苗的生产

VACCINES

IF3.4

2025-03-06

OAAI

Harrison, Mark A.; Atkins, Elizabeth; Faulds-Pain, Alexandra; Heap, John T.; Wren, Brendan W.; Passmore, Ian J.

Recombinant production platform for Group A Streptococcus glycoconjugate vaccines

NPJ VACCINES

IF6.5

2025-01-22

OAAI

Castro, Sowmya Ajay; Passmore, Ian J.; Ndeh, Didier; Shaw, Helen Alexandra; Ruda, Alessandro; Burns, Keira; Thomson, Sarah; Nagar, Rupa; Alagesan, Kathirvel; Reglinski, Mark; Lucas, Kieron; Abouelhadid, Sherif; Schwarz-Linek, Ulrich; Mawas, Fatme; Widmalm, Goeran; Wren, Brendan W.; Dorfmueller, Helge C.

Pathogenicity and virulence of Campylobacter jejuni: What do we really know?空肠弯曲菌的致病性和毒力: 我们真正知道什么？

VIRULENCE

IF5.4

2024-12-08

OAAI

Omole, Zahra; Dorrell, Nick; Elmi, Abdi; Nasher, Fauzy; Gundogdu, Ozan; Wren, Brendan W.

Essential role of proline synthesis and the one-carbon metabolism pathways for systemic virulence of Streptococcus pneumoniae 脯氨酸合成途径与一碳代谢途径在肺炎链球菌全身性毒力中的关键作用

MBIO

IF4.7

2024-11-13

OAAI

Ramos-Sevillano, Elisa; Ercoli, Giuseppe; Betts, Modupeh; Guerra-Assuncao, Jose Afonso; Iverson, Amy; Frank, Matthew; Partridge, Frederick; Lo, Stephanie W.; Fernandes, Vitor E.; Nasher, Fauzy; Wall, Emma; Wren, Brendan; Gordon, Stephen B.; Ferreira, Daniela M.; Heyderman, Rob; Rosch, Jason; Brown, Jeremy S.

Unravelling mechanisms of bacterial recognition by Acanthamoeba: insights into microbial ecology and immune responses

FRONTIERS IN MICROBIOLOGY

IF4.5

2024-08-23

OAAI

Nasher, Fauzy; Wren, Brendan W.

Investigation into the efficiency of diverse N-linking oligosaccharyltransferases for glycoengineering using a standardised cell-free assay

MICROBIAL BIOTECHNOLOGY

IF5.2

2024-06-10

OAAI

Lehri, Burhan; Atkins, Elizabeth; Scott, Timothy A.; Abouelhadid, Sherif; Wren, Brendan W.; Cuccui, Jon

Evaluation of a FlpA Glycoconjugate Vaccine with Ten N-Heptasaccharide Glycan Moieties to reduce Campylobacter jejuni Colonisation in Chickens

VACCINES

IF3.4

2024-04-09

OAAI

Corona-Torres, Ricardo; Vohra, Prerna; Chintoan-Uta, Cosmin; Bremner, Abi; Terra, Vanessa S.; Mauri, Marta; Cuccui, Jon; Vervelde, Lonneke; Wren, Brendan W.; Stevens, Mark P.

Engineering Escherichia coli for increased Und-P availability leads to material improvements in glycan expression technology

MICROBIAL CELL FACTORIES

IF4.9

2024-03-01

OAAI

Kay, Emily J.; Dooda, Manoj K.; Bryant, Joseph C.; Reid, Amanda J.; Wren, Brendan W.; Troutman, Jerry M.; Jorgenson, Matthew A.

Revised Model for the Type A Glycan Biosynthetic Pathway in Clostridioides difficile Strain 630Δerm Based on Quantitative Proteomics of cd0241-cd0244 Mutant Strains

ACS INFECTIOUS DISEASES

IF3.8

2023-11-15

OAAI

Claushuis, Bart; de Ru, Arnoud H.; Rotman, Sarah A.; van Veelen, Peter A.; Dawson, Lisa F.; Wren, Brendan W.; Corver, Jeroen; Smits, Wiep Klaas; Hensbergen, Paul J.

Development of a novel glycoengineering platform for the rapid production of conjugate vaccines 用于快速生产结合疫苗的新型糖工程平台的开发

MICROBIAL CELL FACTORIES

IF4.9

2023-08-18

OAAI

Abouelhadid, Sherif; Atkins, Elizabeth R.; Kay, Emily J.; Passmore, Ian J.; North, Simon J.; Lehri, Burhan; Hitchen, Paul; Bakke, Eirik; Rahman, Mohammed; Bosse, Janine T.; Li, Yanwen; Terra, Vanessa S.; Langford, Paul R.; Dell, Anne; Wren, Brendan W.; Cuccui, Jon

Identification of novel p-cresol inhibitors that reduce Clostridioides difficile's ability to compete with species of the gut microbiome

SCIENTIFIC REPORTS

IF3.9

2023-06-11

OAAI

Harrison, Mark A.; Farthing, Rebecca J.; Allen, Nyasha; Ahern, Lucy M.; Birchall, Kristian; Bond, Michael; Kaur, Harparkash; Wren, Brendan W.; Bergeron, Julien R. C.; Dawson, Lisa F.

研究方向