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C

Cornelis J.M. Melief

leiden university medical center
H指数:86
被引数:3.2万

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工作经历

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荣誉奖项

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Final results of a phase II study of peltopepimut-S and cemiplimab in patients with relapsed/metastatic HPV16+oropharyngeal cancer that progressed with prior anti-PD-1 therapy

佩尔托肽-S和西米普利布在复发/转移性HPV16+口咽癌患者中的II期研究最终结果，这些患者在接受既往抗PD-1治疗后疾病进展。

ANNALS OF ONCOLOGY
IF65.4
2024-09-010
PRE
Kong, A.; Even, C.; Aguilera, B.; Hesselink, M. Klein; Visscher, S.; Chung, C. H.; Park, J. C.; Adkins, D. R.; Salas, S.; Harrington, K. J.; Fayette, J.; Rottey, S.; Algazi, A.; Fury, M. G.; Melief, C. J. M.; Hooftman, L. W.
THERAPEUTIC VACCINES CONSISTING OF CANCER GERMLINE ANTIGEN-BASED SYNTHETIC LONG PEPTIDES ARE IMMUNOGENIC IN HUMAN HEPATOCELLULAR CARCINOMA PATIENTS
JOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
2022-11-070
OA
Rakke, Yannick; Schoenmaekers-Welters, Marij; Noordam, Lisanne; Boekestijn, Sanne; Magre, Luc; Luijten, Robbie; van Gemerden, Rachelle; de Beijer, Monique; Doukas, Michael; Demmers, Jeroen; Wiekmeijer, Anna-Sophia; Krebber, Willem-Jan; Melief, Cornelis; IJzermans, Jan; Kwekkeboom, Jaap; van der Burg, Sjoerd; Buschow, Sonja; Sprengers, Dave
Intradermal vaccination of HPV-16 E6 synthetic peptides conjugated to an optimized Toll-like receptor 2 ligand shows safety and potent T cell immunogenicity in patients with HPV-16 positive (pre-)malignant lesions

与优化的Toll样受体2配体结合的HPV-16 E6合成肽的皮内疫苗接种在HPV-16阳性 (前) 恶性病变患者中显示出安全性和有效的T细胞免疫原性

JOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
2022-10-1916
OAAI
Speetjens, Frank M.; Welters, Marij J. P.; Slingerland, Marije; van Poelgeest, Mariette I. E.; van Steenwijk, Peggy J. de Vos; Roozen, Inge; Boekestijn, Sanne; Loof, Nikki M.; Zom, Gijs G.; Valentijn, A. Rob P. M.; Krebber, Willem-Jan; Meeuwenoord, Nico J.; Janssen, Catharina A. H.; Melief, Cornelis J. M.; van der Marel, Gijs A.; Filippov, Dmitri, V; van der Burg, Sjoerd H.; Gelderblom, Hans; Ossendorp, Ferry
A third vaccination with a single T cell epitope confers protection in a murine model of SARS-CoV-2 infection

用单个T细胞表位进行第三次疫苗接种可在SARS-CoV-2感染的小鼠模型中提供保护

NATURE COMMUNICATIONS
IF15.7
2022-07-0833
OAAI
Pardieck, Iris N.; van der Sluis, Tetje C.; van der Gracht, Esme T., I; Veerkamp, Dominique M. B.; Behr, Felix M.; van Duikeren, Suzanne; Beyrend, Guillaume; Rip, Jasper; Nadafi, Reza; Nejad, Elham Beyranvand; Mulling, Nils; Brasem, Dena J.; Camps, Marcel G. M.; Myeni, Sebenzile K.; Bredenbeek, Peter J.; Kikkert, Marjolein; Kim, Yeonsu; Cicin-Sain, Luka; Abdelaal, Tamim; van Gisbergen, Klaas P. J. M.; Franken, Kees L. M. C.; Drijfhout, Jan Wouter; Melief, Cornelis J. M.; Zondag, Gerben C. M.; Ossendorp, Ferry; Arens, Ramon
Strong vaccine responses during chemotherapy are associated with prolonged cancer survival

化疗期间强烈的疫苗反应与延长癌症生存期有关

SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2020-03-1890
OAAI
Melief, Cornelis J. M.; Welters, Marij J. P.; Vergote, Ignace; Kroep, Judith R.; Kenter, Gemma G.; Ottevanger, Petronella B.; Tjalma, Wiebren A. A.; Denys, Hannelore; van Poelgeest, Mariette I. E.; Nijman, Hans W.; Reyners, Anna K. L.; Velu, Thierry; Goffin, Frederic; Lalisang, Roy, I; Loof, Nikki M.; Boekestijn, Sanne; Krebber, Willem Jan; Hooftman, Leon; Visscher, Sonja; Blumenstein, Brent A.; Stead, Richard B.; Gerritsen, Winald; van der Burg, Sjoerd H.
Formation of Immune Complexes with a Tetanus-Derived B Cell Epitope Boosts Human T Cell Responses to Covalently Linked Peptides in an Ex Vivo Blood Loop System

与破伤风衍生的b细胞表位形成免疫复合物可增强人T细胞对离体血液循环系统中共价连接的肽的反应

JOURNAL OF IMMUNOLOGY
IF3.4
2018-07-0118
OAAI
Fletcher, Erika A. K.; van Maren, Wendy; Cordfunke, Robert; Dinkelaar, Jasper; Codee, Jeroen D. C.; van der Marel, Gijs; Melief, Cornelis J. M.; Ossendorp, Ferry; Drijfhout, Jan Wouter; Mangsbo, Sara M.
Anti-Melanoma immunity and local regression of cutaneous metastases in melanoma patients treated with monobenzone and imiquimod; a phase 2 a trial
ONCOIMMUNOLOGY
IF6.3
2018-01-1536
OAAI
Teulings, Hansje-Eva; Tjin, Esther P. M.; Willemsen, Karina J.; van der Kleij, Stephanie; ter Meulen, Sylvia; Kemp, E. Helen; Krebbers, Gabrielle; van Noesel, Carel J. M.; Franken, Cornelis L. M. C.; Drijfhout, Jan W.; Melief, Cornelis J. M.; Nieuweboer-Krobotova, Ludmila; Nieweg, Omgo E.; van der Hage, Jos A.; van der Veen, J. P. Wietze; Relyveld, Germaine N.; Luiten, Rosalie M.

研究方向

暂未获取到该数据
R
Rienk Offringa
H 指数:78论文数:356被引数:2.2万
F
Ferry Ossendorp
H 指数:72论文数:358被引数:1.8万
S
Sjoerd H. van der Burg
H 指数:0论文数:5被引数:67
J
Jan W. Drijfhout
H 指数:87论文数:400被引数:2.7万
G
Gemma G. Kenter
H 指数:77论文数:368被引数:2.1万
M
Marij J.P. Welters
H 指数:51论文数:329被引数:1.1万
G
Gert Jan Fleuren
H 指数:69论文数:358被引数:1.5万
K
Kees L. M. C. Franken
H 指数:59论文数:212被引数:1.0万
T
Thorbald van Hall
H 指数:55论文数:339被引数:1.1万
R
Ramon Arens
H 指数:0论文数:4被引数:29